JP5351755B2 - ポリ（ａｄｐ−リボース）ポリメラーゼ（ｐａｒｐ）インヒビターとしてのピリジノン及びピリダジノン誘導体 - Google Patents

ポリ（ａｄｐ−リボース）ポリメラーゼ（ｐａｒｐ）インヒビターとしてのピリジノン及びピリダジノン誘導体 Download PDF

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JP5351755B2
JP5351755B2 JP2009512681A JP2009512681A JP5351755B2 JP 5351755 B2 JP5351755 B2 JP 5351755B2 JP 2009512681 A JP2009512681 A JP 2009512681A JP 2009512681 A JP2009512681 A JP 2009512681A JP 5351755 B2 JP5351755 B2 JP 5351755B2
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oxo
methyl
dihydropyridazin
fluorobenzoyl
alkyl
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JP2009538896A (ja
JP2009538896A5 (https=
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ジョーンズ，フィリップ
キンツエル，オラフ
ペスカトーレ，ジヨバンナ
リヤウヘル・ブフィ，ラウラ
シュルツ−ファデムレヒト，カルステン
フェリグノ，フェデリカ
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イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・エルレ・エルレ
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/50—Pyridazines; Hydrogenated pyridazines
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JP2009512681A 2006-05-31 2007-05-25 ポリ（ａｄｐ−リボース）ポリメラーゼ（ｐａｒｐ）インヒビターとしてのピリジノン及びピリダジノン誘導体 Active JP5351755B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0610680.1A GB0610680D0 (en) 2006-05-31 2006-05-31 Therapeutic compounds
GB0610680.1 2006-05-31
PCT/GB2007/050295 WO2007138351A2 (en) 2006-05-31 2007-05-25 Pyridinone and pyridazinone derivatives as inhibitors of poly(adp-ribose)polymerase (parp)

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JP2009538896A JP2009538896A (ja) 2009-11-12
JP2009538896A5 JP2009538896A5 (https=) 2013-08-22
JP5351755B2 true JP5351755B2 (ja) 2013-11-27

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US (1) US8188084B2 (https=)
EP (1) EP2029551B1 (https=)
JP (1) JP5351755B2 (https=)
KR (1) KR101529891B1 (https=)
CN (2) CN101501006A (https=)
AU (1) AU2007266836B2 (https=)
BR (1) BRPI0711741B8 (https=)
CA (1) CA2653529C (https=)
ES (1) ES2702781T3 (https=)
GB (1) GB0610680D0 (https=)
IL (1) IL195113A (https=)
MX (1) MX2008015014A (https=)
NO (1) NO343950B1 (https=)
NZ (1) NZ572815A (https=)
WO (1) WO2007138351A2 (https=)
ZA (1) ZA200809238B (https=)

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GB0622195D0 (en) * 2006-11-08 2006-12-20 Angeletti P Ist Richerche Bio Therapeutic agents
ES2524787T3 (es) 2007-11-15 2014-12-12 Msd Italia S.R.L. Derivados de piridazinona como inhibidores de PARP
DE102008019907A1 (de) * 2008-04-21 2009-10-22 Merck Patent Gmbh Pyridazinonderivate
ES2590987T3 (es) * 2009-04-29 2016-11-24 Glaxo Group Limited Derivados de 5,6,7,8-tetrahidro[1,2,4]triazolo[4,3-a]pirazina como moduladores de P2X7
GB0907515D0 (en) * 2009-04-30 2009-06-10 Glaxo Group Ltd Compounds
EP2552920B1 (en) * 2010-04-02 2017-03-15 Ogeda Sa Novel nk-3 receptor selective antagonist compounds, pharmaceutical composition and methods for use in nk-3 receptors mediated disorders
US10065960B2 (en) 2010-04-02 2018-09-04 Ogeda Sa NK-3 receptor selective antagonist compounds, pharmaceutical composition and methods for use in NK-3 receptors mediated disorders
JP2013526514A (ja) 2010-05-10 2013-06-24 ラディカル・セラピューティックス・インコーポレイテッド リポ酸およびニトロキシド誘導体およびその使用
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