JP5281222B2 - 表面試料から発せられた蛍光シグナルの増幅 - Google Patents

表面試料から発せられた蛍光シグナルの増幅 Download PDF

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Publication number
JP5281222B2
JP5281222B2 JP2001542193A JP2001542193A JP5281222B2 JP 5281222 B2 JP5281222 B2 JP 5281222B2 JP 2001542193 A JP2001542193 A JP 2001542193A JP 2001542193 A JP2001542193 A JP 2001542193A JP 5281222 B2 JP5281222 B2 JP 5281222B2
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Japan
Prior art keywords
thin layer
substrate
surface sample
refractive index
sample
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JP2001542193A
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Japanese (ja)
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JP2003515740A (ja
JP2003515740A5 (enExample
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フランソワ ペロ，
パトリック シャトン，
パトリック プートー，
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Biomerieux SA
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Biomerieux SA
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates

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  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2001542193A 1999-12-02 2000-12-01 表面試料から発せられた蛍光シグナルの増幅 Expired - Fee Related JP5281222B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9915193A FR2801977B1 (fr) 1999-12-02 1999-12-02 Amplification d'un signal de fluorescence emis par un echantillon surfacique
FR99/15193 1999-12-02
PCT/FR2000/003359 WO2001040778A1 (fr) 1999-12-02 2000-12-01 Amplification d'un signal de fluorescence emis par un echantillon surfacique

Publications (3)

Publication Number Publication Date
JP2003515740A JP2003515740A (ja) 2003-05-07
JP2003515740A5 JP2003515740A5 (enExample) 2011-04-07
JP5281222B2 true JP5281222B2 (ja) 2013-09-04

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JP2001542193A Expired - Fee Related JP5281222B2 (ja) 1999-12-02 2000-12-01 表面試料から発せられた蛍光シグナルの増幅

Country Status (6)

Country Link
US (1) US6893876B2 (enExample)
EP (1) EP1234170A1 (enExample)
JP (1) JP5281222B2 (enExample)
AU (1) AU2181701A (enExample)
FR (1) FR2801977B1 (enExample)
WO (1) WO2001040778A1 (enExample)

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US6818185B1 (en) 1999-05-28 2004-11-16 Cepheid Cartridge for conducting a chemical reaction
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
US8111401B2 (en) 1999-11-05 2012-02-07 Robert Magnusson Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats
US7070987B2 (en) 2000-10-30 2006-07-04 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7875434B2 (en) 2000-10-30 2011-01-25 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7142296B2 (en) 2000-10-30 2006-11-28 Sru Biosystems, Inc. Method and apparatus for detecting biomolecular interactions
US7175980B2 (en) 2000-10-30 2007-02-13 Sru Biosystems, Inc. Method of making a plastic colorimetric resonant biosensor device with liquid handling capabilities
US6951715B2 (en) 2000-10-30 2005-10-04 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7094595B2 (en) 2000-10-30 2006-08-22 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7371562B2 (en) 2000-10-30 2008-05-13 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7300803B2 (en) 2000-10-30 2007-11-27 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7023544B2 (en) 2000-10-30 2006-04-04 Sru Biosystems, Inc. Method and instrument for detecting biomolecular interactions
US7101660B2 (en) 2000-10-30 2006-09-05 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US7217574B2 (en) 2000-10-30 2007-05-15 Sru Biosystems, Inc. Method and apparatus for biosensor spectral shift detection
US7615339B2 (en) 2000-10-30 2009-11-10 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US7202076B2 (en) 2000-10-30 2007-04-10 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7575939B2 (en) 2000-10-30 2009-08-18 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7306827B2 (en) 2000-10-30 2007-12-11 Sru Biosystems, Inc. Method and machine for replicating holographic gratings on a substrate
US7264973B2 (en) 2000-10-30 2007-09-04 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant optical biosensor
US7153702B2 (en) 2000-10-30 2006-12-26 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
FR2818382B1 (fr) * 2000-12-20 2003-02-21 Commissariat Energie Atomique Support pour determiner un analyte tel qu'une cible adn ou arn, comportant un filtre spectral selectif
FR2829580B1 (fr) 2001-09-07 2004-02-13 Bio Merieux Procede de lecture, de detection ou de quantification, hybrides ou complexes utilises dans ce procede et biopuce mettant en oeuvre ledit procede
FR2831275B1 (fr) * 2001-10-18 2004-01-30 Commissariat Energie Atomique Substrat revetu d'un film organique transparent et procede de fabrication
FR2832506B1 (fr) 2001-11-22 2004-02-13 Centre Nat Rech Scient Dispositif perfectionne de type bio-puce
US7927822B2 (en) 2002-09-09 2011-04-19 Sru Biosystems, Inc. Methods for screening cells and antibodies
US7429492B2 (en) 2002-09-09 2008-09-30 Sru Biosystems, Inc. Multiwell plates with integrated biosensors and membranes
US7285789B2 (en) * 2003-06-06 2007-10-23 Oc Oerlikon Balzers Ag Optical device for surface-generated fluorescence
US8298780B2 (en) 2003-09-22 2012-10-30 X-Body, Inc. Methods of detection of changes in cells
US7185753B2 (en) * 2004-09-28 2007-03-06 Hartness International, Inc. Shuttle conveyor
US7796251B2 (en) * 2006-03-22 2010-09-14 Itt Manufacturing Enterprises, Inc. Method, apparatus and system for rapid and sensitive standoff detection of surface contaminants
US7511809B2 (en) * 2006-07-07 2009-03-31 Itt Manufacturing Enterprises, Inc. Air sampler module for enhancing the detection capabilities of a chemical detection device or system
WO2008055080A2 (en) * 2006-10-31 2008-05-08 Sru Biosystems, Inc. Method for blocking non-specific protein binding on a functionalized surface
US7636154B1 (en) 2006-12-21 2009-12-22 Itt Manufacturing Enterprises, Inc. Modular optical detection system for point airborne and area surface substance detection
US9134307B2 (en) 2007-07-11 2015-09-15 X-Body, Inc. Method for determining ion channel modulating properties of a test reagent
WO2009009718A1 (en) 2007-07-11 2009-01-15 Sru Biosystems, Inc. Methods of identifying modulators of ion channels
US8257936B2 (en) 2008-04-09 2012-09-04 X-Body Inc. High resolution label free analysis of cellular properties

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649280A (en) * 1985-05-10 1987-03-10 The University Of Rochester Method and system for the enhancement of fluorescence
GB8827853D0 (en) * 1988-11-29 1988-12-29 Ares Serono Res & Dev Ltd Sensor for optical assay
US5082629A (en) * 1989-12-29 1992-01-21 The Board Of The University Of Washington Thin-film spectroscopic sensor
US5552272A (en) * 1993-06-10 1996-09-03 Biostar, Inc. Detection of an analyte by fluorescence using a thin film optical device
PL317379A1 (en) * 1994-05-27 1997-04-01 Ciba Geigy Ag Supercritically excited luminescence detecting process
JP3236199B2 (ja) * 1995-08-25 2001-12-10 日本電気株式会社 平面光導波路型バイオケミカルセンサ
AU2924399A (en) * 1998-02-05 1999-08-23 Novartis Ag Method and device for measuring luminescence
US6130745A (en) * 1999-01-07 2000-10-10 Biometric Imaging, Inc. Optical autofocus for use with microtiter plates

Also Published As

Publication number Publication date
JP2003515740A (ja) 2003-05-07
US20020171045A1 (en) 2002-11-21
FR2801977A1 (fr) 2001-06-08
FR2801977B1 (fr) 2002-05-17
WO2001040778A1 (fr) 2001-06-07
EP1234170A1 (fr) 2002-08-28
AU2181701A (en) 2001-06-12
US6893876B2 (en) 2005-05-17

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