DE59915078D1 - - Google Patents

Info

Publication number
DE59915078D1
DE59915078D1 DE59915078T DE59915078T DE59915078D1 DE 59915078 D1 DE59915078 D1 DE 59915078D1 DE 59915078 T DE59915078 T DE 59915078T DE 59915078 T DE59915078 T DE 59915078T DE 59915078 D1 DE59915078 D1 DE 59915078D1
Authority
DE
Germany
Prior art keywords
luminescence
waveguiding layer
analyte sample
layer
generated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE59915078T
Other languages
German (de)
English (en)
Inventor
Gerd Marowsky
Dieter Neuschaefer
Michael Pawlak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Pharma GmbH Austria
Novartis AG
Original Assignee
Novartis Erfindungen Verwaltungs GmbH
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Erfindungen Verwaltungs GmbH, Novartis AG filed Critical Novartis Erfindungen Verwaltungs GmbH
Application granted granted Critical
Publication of DE59915078D1 publication Critical patent/DE59915078D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/66Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
    • G01N21/69Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence specially adapted for fluids, e.g. molten metal
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76Chemiluminescence; Bioluminescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Plasma & Fusion (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE59915078T 1998-02-05 1999-02-03 Expired - Lifetime DE59915078D1 (enExample)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH27898 1998-02-05
PCT/EP1999/000701 WO1999040415A1 (de) 1998-02-05 1999-02-03 Verfahren und vorrichtung zur lumineszenzmessung

Publications (1)

Publication Number Publication Date
DE59915078D1 true DE59915078D1 (enExample) 2009-10-22

Family

ID=4183357

Family Applications (1)

Application Number Title Priority Date Filing Date
DE59915078T Expired - Lifetime DE59915078D1 (enExample) 1998-02-05 1999-02-03

Country Status (8)

Country Link
US (1) US6710870B1 (enExample)
EP (1) EP1057008B1 (enExample)
JP (1) JP4662623B2 (enExample)
AT (1) ATE442579T1 (enExample)
AU (1) AU2924399A (enExample)
DE (1) DE59915078D1 (enExample)
ES (1) ES2333283T3 (enExample)
WO (1) WO1999040415A1 (enExample)

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US7697052B1 (en) 1999-02-17 2010-04-13 Semiconductor Energy Laboratory Co., Ltd. Electronic view finder utilizing an organic electroluminescence display
FR2801977B1 (fr) * 1999-12-02 2002-05-17 Commissariat Energie Atomique Amplification d'un signal de fluorescence emis par un echantillon surfacique
US7630063B2 (en) * 2000-08-02 2009-12-08 Honeywell International Inc. Miniaturized cytometer for detecting multiple species in a sample
US7978329B2 (en) * 2000-08-02 2011-07-12 Honeywell International Inc. Portable scattering and fluorescence cytometer
US7193711B2 (en) * 2000-07-11 2007-03-20 Maven Technologies, Llc Imaging method and apparatus
US7518724B2 (en) * 2000-07-11 2009-04-14 Maven Technologies Image acquisition, processing, and display
FR2812942B1 (fr) * 2000-08-08 2002-10-31 Commissariat Energie Atomique Dispositif d'imagerie de fluorescence en lumiere polarisee
WO2002012865A1 (de) * 2000-08-09 2002-02-14 Artificial Sensing Instruments Asi Ag Wellenleitergitterstruktur und optische messanordnung
WO2006002150A1 (en) * 2004-06-22 2006-01-05 Applied Materials Israel, Ltd. Wafer inspection system
DE102004034486B4 (de) * 2004-07-16 2007-08-23 Infineon Technologies Ag Verfahren zum Nachweis von Lumineszenzlicht aus einer porösen Trägerstruktur
JP2006234706A (ja) * 2005-02-28 2006-09-07 Fuji Photo Film Co Ltd バイオセンサー
DE102005062377A1 (de) * 2005-12-23 2007-06-28 Bayer Technology Services Gmbh Vorrichtung und Verfahren zum Nachweis von Mykotoxinen
SE529711C2 (sv) 2006-03-22 2007-11-06 Aamic Ab Fluorescensläsare
US20080081330A1 (en) * 2006-09-28 2008-04-03 Helicos Biosciences Corporation Method and devices for analyzing small RNA molecules
US7867783B2 (en) 2007-02-22 2011-01-11 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
JP4843543B2 (ja) * 2007-03-28 2011-12-21 株式会社日立ハイテクノロジーズ 蛍光検出装置及び方法
US7863037B1 (en) 2007-04-04 2011-01-04 Maven Technologies, Llc Ligand binding assays on microarrays in closed multiwell plates
EP2152417B1 (en) 2007-05-04 2018-07-11 Opko Diagnostics, LLC Device and method for analyses in microfluidic systems
US20090041633A1 (en) * 2007-05-14 2009-02-12 Dultz Shane C Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US7799558B1 (en) 2007-05-22 2010-09-21 Dultz Shane C Ligand binding assays on microarrays in closed multiwell plates
US7981664B1 (en) 2008-05-22 2011-07-19 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US8039270B2 (en) * 2008-05-22 2011-10-18 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US10493559B2 (en) * 2008-07-09 2019-12-03 Fei Company Method and apparatus for laser machining
JP2010160087A (ja) * 2009-01-09 2010-07-22 Nitto Denko Corp 光導波路型ケミカルセンサ
EP2391451B1 (en) 2009-02-02 2018-09-12 Opko Diagnostics, LLC Structures for controlling light interaction with microfluidic devices
EP2269737B1 (en) * 2009-07-02 2017-09-13 Amic AB Assay device comprising serial reaction zones
US8649014B2 (en) * 2009-10-02 2014-02-11 Lehigh University Vertical plasmonic Mach-Zehnder interferometer
US8355133B2 (en) * 2009-12-30 2013-01-15 Maven Technologies, Llc Biological testing with sawtooth-shaped prisms
JP2015514960A (ja) * 2011-12-28 2015-05-21 ポリマー テクノロジー システムズ インコーポレーテッド 検体モニタ
MX362555B (es) 2012-03-05 2019-01-24 Oy Arctic Partners Ab Metodos y aparatos para predecir riesgo de cancer de prostata y volumen de glandula prostatica.
EP3045895A1 (en) * 2015-01-13 2016-07-20 ARKRAY, Inc. Plasma spectrochemical analysis method and plasma spectrochemical analyzer
DE102015205699B4 (de) * 2015-03-30 2016-11-10 Technische Universität Dresden Spektrometer mit Monomodewellenleiter
DE102015214414B4 (de) * 2015-07-29 2020-10-22 Berthold Technologies Gmbh & Co. Kg Verfahren und System zur Ermittlung biologischer Eigenschaften von Proben
JP7219718B2 (ja) * 2017-03-31 2023-02-08 ユニバーシティ オブ ストラスクライド 赤外分光システム
CN112665618B (zh) * 2020-12-17 2022-05-17 安徽中元新材料技术有限公司 一种基于形态学的波长敏感模式提取装置及方法

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GB8415018D0 (en) * 1984-06-13 1984-07-18 Unilever Plc Chemical test procedures
EP0226604B1 (de) * 1985-05-29 1991-08-21 Artificial Sensing Instruments ASI AG Optischer sensor zum selektiven nachweis von substanzen und zum nachweis von brechzahländerungen in messubstanzen
US4945245A (en) * 1986-01-14 1990-07-31 Levin Herman W Evanescent wave background fluorescence/absorbance detection
EP0244394B1 (de) 1986-04-23 1992-06-17 AVL Medical Instruments AG Sensorelement zur Bestimmung von Stoffkonzentrationen
AT390677B (de) * 1986-10-10 1990-06-11 Avl Verbrennungskraft Messtech Sensorelement zur bestimmung von stoffkonzentrationen
US5166515A (en) * 1989-06-22 1992-11-24 Applied Research Systems Ars Holding, N.V. Method of optical analysis of a fluid including an optical waveguide
DE59109246D1 (de) * 1990-05-03 2003-04-03 Hoffmann La Roche Mikrooptischer Sensor
US5192510A (en) * 1991-01-30 1993-03-09 E. I. Du Pont De Nemours And Company Apparatus for performing fluorescent assays which separates bulk and evanescent fluorescence
US5677196A (en) * 1993-05-18 1997-10-14 University Of Utah Research Foundation Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
US5439647A (en) * 1994-02-25 1995-08-08 Fiberchem, Inc. Chip level waveguide sensor
JPH07318481A (ja) 1994-05-25 1995-12-08 Daikin Ind Ltd 光学的測定方法およびその装置
CN1149335A (zh) * 1994-05-27 1997-05-07 希巴-盖吉股份公司 探测短暂受激发光的方法
MX9708698A (es) 1995-05-12 1998-02-28 Novartis Ag Plataforma de sensor y metodo para la deteccion paralela de una pluralidad de analitos utilizando luminescencia evanescentemente excitada.
AT403745B (de) 1996-02-29 1998-05-25 Avl Verbrennungskraft Messtech Messanordnung mit einem für anregungs- und messstrahlung transparentem trägerelement
JP3748571B2 (ja) * 1996-11-18 2006-02-22 ノバルティス アクチエンゲゼルシャフト 測定装置及びその使用方法
US6208791B1 (en) * 1999-04-19 2001-03-27 Gemfire Corporation Optically integrating pixel microstructure

Also Published As

Publication number Publication date
ES2333283T3 (es) 2010-02-18
US6710870B1 (en) 2004-03-23
ATE442579T1 (de) 2009-09-15
EP1057008B1 (de) 2009-09-09
WO1999040415A1 (de) 1999-08-12
AU2924399A (en) 1999-08-23
JP2002502967A (ja) 2002-01-29
JP4662623B2 (ja) 2011-03-30
EP1057008A1 (de) 2000-12-06

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