ES2047334T3 - Metodo de analisis optico. - Google Patents
Metodo de analisis optico.Info
- Publication number
- ES2047334T3 ES2047334T3 ES90909063T ES90909063T ES2047334T3 ES 2047334 T3 ES2047334 T3 ES 2047334T3 ES 90909063 T ES90909063 T ES 90909063T ES 90909063 T ES90909063 T ES 90909063T ES 2047334 T3 ES2047334 T3 ES 2047334T3
- Authority
- ES
- Spain
- Prior art keywords
- pct
- optical
- date dec
- optical analysis
- sec
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N2021/0346—Capillary cells; Microcells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N2021/6463—Optics
- G01N2021/6465—Angular discrimination
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Optics & Photonics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
LA INVENCION SE REFIERE A UN METODO PARA ANALISIS OPTICO QUE PUEDE UTILIZARSE VENTAJOSAMENTE, JUNTO CON TECNICAS DE ENSAYOS OPTICOS, PARTICULARMENTE EN AQUELLOS EN LAS QUE SE VAN A ANALIZAR LAS SEÑALES EVANESCENTES. EL METODO UTILIZA LAS PROPIEDADES DE UNA ESTRUCTURA OPTICA (DESCRITA AQUI), QUE PERMITE UNA DISCRIMINACION ANGULAR FACIL DE LAS SEÑALES OPTICAS QUE EMERGEN DE UN OBJETO SOMETIDO A PRUEBA. LA INVENCION SE REFIERE TAMBIEN, A LOS APARATOS A UTILIZAR EN DICHO METODO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898914343A GB8914343D0 (en) | 1989-06-22 | 1989-06-22 | Optical method of analysis |
GB909008261A GB9008261D0 (en) | 1990-04-11 | 1990-04-11 | Method of improving assay sensitivity |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2047334T3 true ES2047334T3 (es) | 1994-02-16 |
Family
ID=26295521
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90909063T Expired - Lifetime ES2047334T3 (es) | 1989-06-22 | 1990-06-21 | Metodo de analisis optico. |
Country Status (10)
Country | Link |
---|---|
US (1) | US5166515A (es) |
EP (1) | EP0429612B1 (es) |
JP (1) | JP2612641B2 (es) |
AT (1) | ATE98773T1 (es) |
AU (1) | AU619120B2 (es) |
CA (1) | CA2033168C (es) |
DE (1) | DE69005270T2 (es) |
DK (1) | DK0429612T3 (es) |
ES (1) | ES2047334T3 (es) |
WO (1) | WO1990015985A1 (es) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9008261D0 (en) * | 1990-04-11 | 1990-06-13 | Ares Serono Res & Dev Ltd | Method of improving assay sensitivity |
WO1992008966A1 (en) * | 1990-11-13 | 1992-05-29 | Block Myron J | Fluorescence assay apparatus |
US5192510A (en) * | 1991-01-30 | 1993-03-09 | E. I. Du Pont De Nemours And Company | Apparatus for performing fluorescent assays which separates bulk and evanescent fluorescence |
AU749504B2 (en) * | 1993-05-18 | 2002-06-27 | University Of Utah Research Foundation | Apparatus and methods for multianalyte homogeneous fluoroimmunoassays |
US5677196A (en) * | 1993-05-18 | 1997-10-14 | University Of Utah Research Foundation | Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays |
US5512492A (en) * | 1993-05-18 | 1996-04-30 | University Of Utah Research Foundation | Waveguide immunosensor with coating chemistry providing enhanced sensitivity |
ES2169079T3 (es) * | 1993-05-18 | 2002-07-01 | Univ Utah Res Found | Aparato y metodos para fluoroinmunoensayos homogeneos multianalitos. |
US5919712A (en) | 1993-05-18 | 1999-07-06 | University Of Utah Research Foundation | Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays |
JPH08116961A (ja) * | 1994-10-25 | 1996-05-14 | Hamamatsu Photonics Kk | 培養観測用容器及び観測装置 |
US5814565A (en) * | 1995-02-23 | 1998-09-29 | University Of Utah Research Foundation | Integrated optic waveguide immunosensor |
US5745231A (en) * | 1995-06-12 | 1998-04-28 | American Research Corporation Of Virginia | Method of fluorescence analysis comprising evanescent wave excitation and out-of-plane photodetection |
US5832165A (en) | 1996-08-28 | 1998-11-03 | University Of Utah Research Foundation | Composite waveguide for solid phase binding assays |
US6395558B1 (en) * | 1996-08-29 | 2002-05-28 | Zeptosens Ag | Optical chemical/biochemical sensor |
US6222619B1 (en) | 1997-09-18 | 2001-04-24 | University Of Utah Research Foundation | Diagnostic device and method |
EP1057008B1 (de) * | 1998-02-05 | 2009-09-09 | Novartis AG | Verfahren und vorrichtung zur lumineszenzmessung |
US6300638B1 (en) | 1998-11-12 | 2001-10-09 | Calspan Srl Corporation | Modular probe for total internal reflection fluorescence spectroscopy |
WO2001025759A1 (de) * | 1999-10-01 | 2001-04-12 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren und einrichtung zur bestimmung von substanzen, wie z.b. dna-sequenzen, in einer probe |
US6759663B2 (en) * | 2000-01-20 | 2004-07-06 | Ikonisys, Inc. | Device and method for detecting and localizing cells by means of photosensitive waveguides |
WO2002001194A1 (en) | 2000-06-25 | 2002-01-03 | Affymetrix, Inc. | Optically active substrates |
ATE281658T1 (de) * | 2000-08-18 | 2004-11-15 | Koninkl Philips Electronics Nv | Optisches bauteil und seine herstellung |
US6947651B2 (en) * | 2001-05-10 | 2005-09-20 | Georgia Tech Research Corporation | Optical waveguides formed from nano air-gap inter-layer dielectric materials and methods of fabrication thereof |
US6890619B2 (en) * | 2001-11-13 | 2005-05-10 | Agilent Technologies, Inc. | Optical systems and refractive index-matching compositions |
US7029631B2 (en) * | 2002-04-19 | 2006-04-18 | Agilent Technologies, Inc. | Apparatus for improved light collection |
US7154598B2 (en) * | 2002-07-12 | 2006-12-26 | Decision Biomarkers, Inc. | Excitation and imaging of fluorescent arrays |
US7196788B2 (en) * | 2002-07-22 | 2007-03-27 | Ikonisys, Inc. | Device and method for detecting and localizing cells by means of photosensitive waveguides |
US7384742B2 (en) * | 2002-08-16 | 2008-06-10 | Decision Biomarkers, Inc. | Substrates for isolating reacting and microscopically analyzing materials |
US20060127946A1 (en) * | 2002-08-16 | 2006-06-15 | Montagu Jean I | Reading of fluorescent arrays |
US20070196863A1 (en) * | 2006-02-17 | 2007-08-23 | Hanson Technologies, Inc. | Prion protein detection |
US20080026373A1 (en) * | 2006-07-26 | 2008-01-31 | Rodionova Natalia A | Assays Based On Light Emission From Analyte Complexes Within A Cassette |
US8300993B2 (en) * | 2009-03-02 | 2012-10-30 | Mbio Diagnostics, Inc. | Waveguide with integrated lens |
US9212995B2 (en) | 2009-03-02 | 2015-12-15 | Mbio Diagnostics, Inc. | System and method for detecting multiple molecules in one assay |
US9658222B2 (en) | 2009-03-02 | 2017-05-23 | Mbio Diagnostics, Inc. | Planar waveguide based cartridges and associated methods for detecting target analyte |
US8331751B2 (en) | 2009-03-02 | 2012-12-11 | mBio Diagnositcs, Inc. | Planar optical waveguide with core of low-index-of-refraction interrogation medium |
JP5351815B2 (ja) * | 2010-03-31 | 2013-11-27 | 富士フイルム株式会社 | 光学部材および表面プラズモン共鳴測定装置 |
US9453791B2 (en) * | 2014-07-01 | 2016-09-27 | Octrolix Bv | Flow cytometry system and method |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3990779A (en) * | 1975-07-24 | 1976-11-09 | International Telephone And Telegraph Corporation | Single optical fiber connector |
US4575181A (en) * | 1983-04-26 | 1986-03-11 | Tokyo Shibaura Denki Kabushiki Kaisha | Optical fiber assembly with cladding light scattering means |
DE3568874D1 (en) * | 1984-06-13 | 1989-04-20 | Ares Serono Inc | Photometric instruments, their use in methods of optical analysis, and ancillary devices therefor |
AT383684B (de) * | 1984-09-17 | 1987-08-10 | Avl Verbrennungskraft Messtech | Anordnung zur fluoreszenzoptischen messung von stoffkonzentrationen in einer probe |
US4668636A (en) * | 1984-11-06 | 1987-05-26 | Battelle Memorial Institute | Analytical assembly usable in apparatuses for optically determining species in solution |
US4844869A (en) * | 1985-09-09 | 1989-07-04 | Ord, Inc. | Immunoassay apparatus |
AU604364B2 (en) * | 1987-08-13 | 1990-12-13 | Dow Chemical Company, The | Sulfur dioxide removal from gas streams using hydroxyalkyl substituted piperazinones |
-
1990
- 1990-06-21 US US07/623,817 patent/US5166515A/en not_active Expired - Lifetime
- 1990-06-21 DK DK90909063.1T patent/DK0429612T3/da active
- 1990-06-21 EP EP90909063A patent/EP0429612B1/en not_active Expired - Lifetime
- 1990-06-21 JP JP2508670A patent/JP2612641B2/ja not_active Expired - Fee Related
- 1990-06-21 DE DE69005270T patent/DE69005270T2/de not_active Expired - Fee Related
- 1990-06-21 WO PCT/GB1990/000953 patent/WO1990015985A1/en active IP Right Grant
- 1990-06-21 AT AT90909063T patent/ATE98773T1/de not_active IP Right Cessation
- 1990-06-21 ES ES90909063T patent/ES2047334T3/es not_active Expired - Lifetime
- 1990-06-21 AU AU58277/90A patent/AU619120B2/en not_active Ceased
- 1990-06-21 CA CA002033168A patent/CA2033168C/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2612641B2 (ja) | 1997-05-21 |
DE69005270T2 (de) | 1994-07-07 |
EP0429612A1 (en) | 1991-06-05 |
WO1990015985A1 (en) | 1990-12-27 |
DE69005270D1 (de) | 1994-01-27 |
AU619120B2 (en) | 1992-01-16 |
AU5827790A (en) | 1991-01-08 |
ATE98773T1 (de) | 1994-01-15 |
CA2033168C (en) | 1998-08-18 |
US5166515A (en) | 1992-11-24 |
DK0429612T3 (da) | 1994-03-07 |
EP0429612B1 (en) | 1993-12-15 |
JPH04501612A (ja) | 1992-03-19 |
CA2033168A1 (en) | 1990-12-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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