DE69005270T2 - Verfahren zur optischen analyse. - Google Patents

Verfahren zur optischen analyse.

Info

Publication number
DE69005270T2
DE69005270T2 DE69005270T DE69005270T DE69005270T2 DE 69005270 T2 DE69005270 T2 DE 69005270T2 DE 69005270 T DE69005270 T DE 69005270T DE 69005270 T DE69005270 T DE 69005270T DE 69005270 T2 DE69005270 T2 DE 69005270T2
Authority
DE
Germany
Prior art keywords
pct
optical
date dec
sec
optical analysis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69005270T
Other languages
English (en)
Other versions
DE69005270D1 (de
Inventor
John Attridge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Research Systems ARS Holding NV
Original Assignee
Ars Holding 89 Nv Curacao
ARS HOLDING 89 NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898914343A external-priority patent/GB8914343D0/en
Priority claimed from GB909008261A external-priority patent/GB9008261D0/en
Application filed by Ars Holding 89 Nv Curacao, ARS HOLDING 89 NV filed Critical Ars Holding 89 Nv Curacao
Publication of DE69005270D1 publication Critical patent/DE69005270D1/de
Application granted granted Critical
Publication of DE69005270T2 publication Critical patent/DE69005270T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G01N2021/6465—Angular discrimination
DE69005270T 1989-06-22 1990-06-21 Verfahren zur optischen analyse. Expired - Fee Related DE69005270T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898914343A GB8914343D0 (en) 1989-06-22 1989-06-22 Optical method of analysis
GB909008261A GB9008261D0 (en) 1990-04-11 1990-04-11 Method of improving assay sensitivity
PCT/GB1990/000953 WO1990015985A1 (en) 1989-06-22 1990-06-21 Method of optical analysis

Publications (2)

Publication Number Publication Date
DE69005270D1 DE69005270D1 (de) 1994-01-27
DE69005270T2 true DE69005270T2 (de) 1994-07-07

Family

ID=26295521

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69005270T Expired - Fee Related DE69005270T2 (de) 1989-06-22 1990-06-21 Verfahren zur optischen analyse.

Country Status (10)

Country Link
US (1) US5166515A (de)
EP (1) EP0429612B1 (de)
JP (1) JP2612641B2 (de)
AT (1) ATE98773T1 (de)
AU (1) AU619120B2 (de)
CA (1) CA2033168C (de)
DE (1) DE69005270T2 (de)
DK (1) DK0429612T3 (de)
ES (1) ES2047334T3 (de)
WO (1) WO1990015985A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9008261D0 (en) * 1990-04-11 1990-06-13 Ares Serono Res & Dev Ltd Method of improving assay sensitivity
WO1992008966A1 (en) * 1990-11-13 1992-05-29 Block Myron J Fluorescence assay apparatus
US5192510A (en) * 1991-01-30 1993-03-09 E. I. Du Pont De Nemours And Company Apparatus for performing fluorescent assays which separates bulk and evanescent fluorescence
US5677196A (en) * 1993-05-18 1997-10-14 University Of Utah Research Foundation Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
AU749504B2 (en) * 1993-05-18 2002-06-27 University Of Utah Research Foundation Apparatus and methods for multianalyte homogeneous fluoroimmunoassays
DE69429262T2 (de) * 1993-05-18 2002-07-25 Univ Utah Res Found Vorrichtung und verfahren fuer homogene multianalyt-immuno-assays
US5512492A (en) * 1993-05-18 1996-04-30 University Of Utah Research Foundation Waveguide immunosensor with coating chemistry providing enhanced sensitivity
US5919712A (en) 1993-05-18 1999-07-06 University Of Utah Research Foundation Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
JPH08116961A (ja) * 1994-10-25 1996-05-14 Hamamatsu Photonics Kk 培養観測用容器及び観測装置
US5814565A (en) 1995-02-23 1998-09-29 University Of Utah Research Foundation Integrated optic waveguide immunosensor
US5745231A (en) * 1995-06-12 1998-04-28 American Research Corporation Of Virginia Method of fluorescence analysis comprising evanescent wave excitation and out-of-plane photodetection
US5832165A (en) 1996-08-28 1998-11-03 University Of Utah Research Foundation Composite waveguide for solid phase binding assays
EP0922214A1 (de) * 1996-08-29 1999-06-16 Novartis AG Optischer chemischer/biochemischer fühler
US6222619B1 (en) 1997-09-18 2001-04-24 University Of Utah Research Foundation Diagnostic device and method
DE59915078D1 (de) * 1998-02-05 2009-10-22 Novartis Ag
US6300638B1 (en) 1998-11-12 2001-10-09 Calspan Srl Corporation Modular probe for total internal reflection fluorescence spectroscopy
EP1218727A1 (de) * 1999-10-01 2002-07-03 Fraunhofer-Gesellschaft Zur Förderung Der Angewandten Forschung E.V. Verfahren und einrichtung zur bestimmung von substanzen, wie z.b. dna-sequenzen, in einer probe
CA2397943A1 (en) * 2000-01-20 2001-07-26 Ikonisys, Inc. Device and method for detecting and localizing cells by means of photosensitive waveguides
EP1311824A4 (de) 2000-06-25 2010-12-08 Affymetrix Inc Optisch aktive substrate
ATE281658T1 (de) * 2000-08-18 2004-11-15 Koninkl Philips Electronics Nv Optisches bauteil und seine herstellung
US6947651B2 (en) * 2001-05-10 2005-09-20 Georgia Tech Research Corporation Optical waveguides formed from nano air-gap inter-layer dielectric materials and methods of fabrication thereof
US6890619B2 (en) * 2001-11-13 2005-05-10 Agilent Technologies, Inc. Optical systems and refractive index-matching compositions
US7029631B2 (en) * 2002-04-19 2006-04-18 Agilent Technologies, Inc. Apparatus for improved light collection
US7154598B2 (en) * 2002-07-12 2006-12-26 Decision Biomarkers, Inc. Excitation and imaging of fluorescent arrays
US7196788B2 (en) * 2002-07-22 2007-03-27 Ikonisys, Inc. Device and method for detecting and localizing cells by means of photosensitive waveguides
US20060127946A1 (en) * 2002-08-16 2006-06-15 Montagu Jean I Reading of fluorescent arrays
US7384742B2 (en) * 2002-08-16 2008-06-10 Decision Biomarkers, Inc. Substrates for isolating reacting and microscopically analyzing materials
US20070196863A1 (en) * 2006-02-17 2007-08-23 Hanson Technologies, Inc. Prion protein detection
US20080026373A1 (en) * 2006-07-26 2008-01-31 Rodionova Natalia A Assays Based On Light Emission From Analyte Complexes Within A Cassette
US8300993B2 (en) * 2009-03-02 2012-10-30 Mbio Diagnostics, Inc. Waveguide with integrated lens
US9212995B2 (en) 2009-03-02 2015-12-15 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay
US8331751B2 (en) * 2009-03-02 2012-12-11 mBio Diagnositcs, Inc. Planar optical waveguide with core of low-index-of-refraction interrogation medium
US9658222B2 (en) 2009-03-02 2017-05-23 Mbio Diagnostics, Inc. Planar waveguide based cartridges and associated methods for detecting target analyte
JP5351815B2 (ja) * 2010-03-31 2013-11-27 富士フイルム株式会社 光学部材および表面プラズモン共鳴測定装置
US9453791B2 (en) * 2014-07-01 2016-09-27 Octrolix Bv Flow cytometry system and method

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3990779A (en) * 1975-07-24 1976-11-09 International Telephone And Telegraph Corporation Single optical fiber connector
US4575181A (en) * 1983-04-26 1986-03-11 Tokyo Shibaura Denki Kabushiki Kaisha Optical fiber assembly with cladding light scattering means
CA1231136A (en) * 1984-06-13 1988-01-05 Ian A. Shanks Capillary action chemical test device
AT383684B (de) * 1984-09-17 1987-08-10 Avl Verbrennungskraft Messtech Anordnung zur fluoreszenzoptischen messung von stoffkonzentrationen in einer probe
US4668636A (en) * 1984-11-06 1987-05-26 Battelle Memorial Institute Analytical assembly usable in apparatuses for optically determining species in solution
US4844869A (en) * 1985-09-09 1989-07-04 Ord, Inc. Immunoassay apparatus
AU604364B2 (en) * 1987-08-13 1990-12-13 Dow Chemical Company, The Sulfur dioxide removal from gas streams using hydroxyalkyl substituted piperazinones

Also Published As

Publication number Publication date
JP2612641B2 (ja) 1997-05-21
DE69005270D1 (de) 1994-01-27
EP0429612B1 (de) 1993-12-15
EP0429612A1 (de) 1991-06-05
AU5827790A (en) 1991-01-08
CA2033168A1 (en) 1990-12-23
ATE98773T1 (de) 1994-01-15
ES2047334T3 (es) 1994-02-16
WO1990015985A1 (en) 1990-12-27
US5166515A (en) 1992-11-24
JPH04501612A (ja) 1992-03-19
DK0429612T3 (da) 1994-03-07
CA2033168C (en) 1998-08-18
AU619120B2 (en) 1992-01-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: APPLIED RESEARCH SYSTEMS ARS HOLDING N.V., CURACAO

8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC

8339 Ceased/non-payment of the annual fee