FR2801977B1 - Amplification d'un signal de fluorescence emis par un echantillon surfacique - Google Patents

Amplification d'un signal de fluorescence emis par un echantillon surfacique

Info

Publication number
FR2801977B1
FR2801977B1 FR9915193A FR9915193A FR2801977B1 FR 2801977 B1 FR2801977 B1 FR 2801977B1 FR 9915193 A FR9915193 A FR 9915193A FR 9915193 A FR9915193 A FR 9915193A FR 2801977 B1 FR2801977 B1 FR 2801977B1
Authority
FR
France
Prior art keywords
surfacic
amplification
sample
fluorescence signal
signal emitted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9915193A
Other languages
English (en)
French (fr)
Other versions
FR2801977A1 (fr
Inventor
Francois Perraut
Patrick Chaton
Patrick Pouteau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA filed Critical Commissariat a lEnergie Atomique CEA
Priority to FR9915193A priority Critical patent/FR2801977B1/fr
Priority to US10/129,948 priority patent/US6893876B2/en
Priority to PCT/FR2000/003359 priority patent/WO2001040778A1/fr
Priority to JP2001542193A priority patent/JP5281222B2/ja
Priority to AU21817/01A priority patent/AU2181701A/en
Priority to EP00985381A priority patent/EP1234170A1/fr
Publication of FR2801977A1 publication Critical patent/FR2801977A1/fr
Application granted granted Critical
Publication of FR2801977B1 publication Critical patent/FR2801977B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates

Landscapes

  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
FR9915193A 1999-12-02 1999-12-02 Amplification d'un signal de fluorescence emis par un echantillon surfacique Expired - Fee Related FR2801977B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR9915193A FR2801977B1 (fr) 1999-12-02 1999-12-02 Amplification d'un signal de fluorescence emis par un echantillon surfacique
US10/129,948 US6893876B2 (en) 1999-12-02 2000-12-01 Enhancing surface-generated fluorescence signal emitted by a sample
PCT/FR2000/003359 WO2001040778A1 (fr) 1999-12-02 2000-12-01 Amplification d'un signal de fluorescence emis par un echantillon surfacique
JP2001542193A JP5281222B2 (ja) 1999-12-02 2000-12-01 表面試料から発せられた蛍光シグナルの増幅
AU21817/01A AU2181701A (en) 1999-12-02 2000-12-01 Enhancing surface-generated fluorescence signal emitted by sample
EP00985381A EP1234170A1 (fr) 1999-12-02 2000-12-01 Amplification d'un signal de fluorescence emis par un echantillon surfacique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9915193A FR2801977B1 (fr) 1999-12-02 1999-12-02 Amplification d'un signal de fluorescence emis par un echantillon surfacique

Publications (2)

Publication Number Publication Date
FR2801977A1 FR2801977A1 (fr) 2001-06-08
FR2801977B1 true FR2801977B1 (fr) 2002-05-17

Family

ID=9552796

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9915193A Expired - Fee Related FR2801977B1 (fr) 1999-12-02 1999-12-02 Amplification d'un signal de fluorescence emis par un echantillon surfacique

Country Status (6)

Country Link
US (1) US6893876B2 (enExample)
EP (1) EP1234170A1 (enExample)
JP (1) JP5281222B2 (enExample)
AU (1) AU2181701A (enExample)
FR (1) FR2801977B1 (enExample)
WO (1) WO2001040778A1 (enExample)

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6951715B2 (en) 2000-10-30 2005-10-04 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7023544B2 (en) 2000-10-30 2006-04-04 Sru Biosystems, Inc. Method and instrument for detecting biomolecular interactions
US7070987B2 (en) 2000-10-30 2006-07-04 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7101660B2 (en) 2000-10-30 2006-09-05 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US7142296B2 (en) 2000-10-30 2006-11-28 Sru Biosystems, Inc. Method and apparatus for detecting biomolecular interactions
US7153702B2 (en) 2000-10-30 2006-12-26 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7175980B2 (en) 2000-10-30 2007-02-13 Sru Biosystems, Inc. Method of making a plastic colorimetric resonant biosensor device with liquid handling capabilities
US7202076B2 (en) 2000-10-30 2007-04-10 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7217574B2 (en) 2000-10-30 2007-05-15 Sru Biosystems, Inc. Method and apparatus for biosensor spectral shift detection
US7264973B2 (en) 2000-10-30 2007-09-04 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant optical biosensor
US7300803B2 (en) 2000-10-30 2007-11-27 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7306827B2 (en) 2000-10-30 2007-12-11 Sru Biosystems, Inc. Method and machine for replicating holographic gratings on a substrate
US7371562B2 (en) 2000-10-30 2008-05-13 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7422891B2 (en) 2000-10-30 2008-09-09 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7429492B2 (en) 2002-09-09 2008-09-30 Sru Biosystems, Inc. Multiwell plates with integrated biosensors and membranes
US7575939B2 (en) 2000-10-30 2009-08-18 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7615339B2 (en) 2000-10-30 2009-11-10 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US7875434B2 (en) 2000-10-30 2011-01-25 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7927822B2 (en) 2002-09-09 2011-04-19 Sru Biosystems, Inc. Methods for screening cells and antibodies
US8257936B2 (en) 2008-04-09 2012-09-04 X-Body Inc. High resolution label free analysis of cellular properties
US8298780B2 (en) 2003-09-22 2012-10-30 X-Body, Inc. Methods of detection of changes in cells
US8514391B2 (en) 1999-11-05 2013-08-20 Board Of Regents, The University Of Texas System Resonant waveguide-grating devices and methods for using same
US9134307B2 (en) 2007-07-11 2015-09-15 X-Body, Inc. Method for determining ion channel modulating properties of a test reagent

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6818185B1 (en) 1999-05-28 2004-11-16 Cepheid Cartridge for conducting a chemical reaction
US8111401B2 (en) 1999-11-05 2012-02-07 Robert Magnusson Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats
FR2818382B1 (fr) * 2000-12-20 2003-02-21 Commissariat Energie Atomique Support pour determiner un analyte tel qu'une cible adn ou arn, comportant un filtre spectral selectif
FR2829580B1 (fr) 2001-09-07 2004-02-13 Bio Merieux Procede de lecture, de detection ou de quantification, hybrides ou complexes utilises dans ce procede et biopuce mettant en oeuvre ledit procede
FR2831275B1 (fr) * 2001-10-18 2004-01-30 Commissariat Energie Atomique Substrat revetu d'un film organique transparent et procede de fabrication
FR2832506B1 (fr) 2001-11-22 2004-02-13 Centre Nat Rech Scient Dispositif perfectionne de type bio-puce
US7285789B2 (en) * 2003-06-06 2007-10-23 Oc Oerlikon Balzers Ag Optical device for surface-generated fluorescence
US7185753B2 (en) * 2004-09-28 2007-03-06 Hartness International, Inc. Shuttle conveyor
US7796251B2 (en) * 2006-03-22 2010-09-14 Itt Manufacturing Enterprises, Inc. Method, apparatus and system for rapid and sensitive standoff detection of surface contaminants
US7511809B2 (en) * 2006-07-07 2009-03-31 Itt Manufacturing Enterprises, Inc. Air sampler module for enhancing the detection capabilities of a chemical detection device or system
WO2008055080A2 (en) * 2006-10-31 2008-05-08 Sru Biosystems, Inc. Method for blocking non-specific protein binding on a functionalized surface
US7636154B1 (en) 2006-12-21 2009-12-22 Itt Manufacturing Enterprises, Inc. Modular optical detection system for point airborne and area surface substance detection
WO2009009718A1 (en) 2007-07-11 2009-01-15 Sru Biosystems, Inc. Methods of identifying modulators of ion channels

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649280A (en) * 1985-05-10 1987-03-10 The University Of Rochester Method and system for the enhancement of fluorescence
GB8827853D0 (en) * 1988-11-29 1988-12-29 Ares Serono Res & Dev Ltd Sensor for optical assay
US5082629A (en) * 1989-12-29 1992-01-21 The Board Of The University Of Washington Thin-film spectroscopic sensor
US5552272A (en) * 1993-06-10 1996-09-03 Biostar, Inc. Detection of an analyte by fluorescence using a thin film optical device
PL317379A1 (en) * 1994-05-27 1997-04-01 Ciba Geigy Ag Supercritically excited luminescence detecting process
JP3236199B2 (ja) * 1995-08-25 2001-12-10 日本電気株式会社 平面光導波路型バイオケミカルセンサ
AU2924399A (en) * 1998-02-05 1999-08-23 Novartis Ag Method and device for measuring luminescence
US6130745A (en) * 1999-01-07 2000-10-10 Biometric Imaging, Inc. Optical autofocus for use with microtiter plates

Cited By (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8514391B2 (en) 1999-11-05 2013-08-20 Board Of Regents, The University Of Texas System Resonant waveguide-grating devices and methods for using same
US7371562B2 (en) 2000-10-30 2008-05-13 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US8101423B2 (en) 2000-10-30 2012-01-24 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7101660B2 (en) 2000-10-30 2006-09-05 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US7142296B2 (en) 2000-10-30 2006-11-28 Sru Biosystems, Inc. Method and apparatus for detecting biomolecular interactions
US7148964B2 (en) 2000-10-30 2006-12-12 Sru Biosystems, Inc. Method and apparatus for detecting biomolecular interactions
US7153702B2 (en) 2000-10-30 2006-12-26 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7158230B2 (en) 2000-10-30 2007-01-02 Sru Biosystems, Inc. Method and apparatus for detecting biomolecular interactions
US7170599B2 (en) 2000-10-30 2007-01-30 Sru Biosystems, Inc. Method and instrument for detecting biomolecular interactions
US7175980B2 (en) 2000-10-30 2007-02-13 Sru Biosystems, Inc. Method of making a plastic colorimetric resonant biosensor device with liquid handling capabilities
US7202076B2 (en) 2000-10-30 2007-04-10 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7217574B2 (en) 2000-10-30 2007-05-15 Sru Biosystems, Inc. Method and apparatus for biosensor spectral shift detection
US7264973B2 (en) 2000-10-30 2007-09-04 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant optical biosensor
US7292336B2 (en) 2000-10-30 2007-11-06 Sru Biosystems, Inc. Method and instrument for detecting biomolecular interactions
US7298477B1 (en) 2000-10-30 2007-11-20 Sru Biosystems, Inc. Method and apparatus for detecting biomolecular interactions
US7300803B2 (en) 2000-10-30 2007-11-27 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7301628B2 (en) 2000-10-30 2007-11-27 Sru Biosystems, Inc. Method and apparatus for detecting biomolecular interactions
US7306827B2 (en) 2000-10-30 2007-12-11 Sru Biosystems, Inc. Method and machine for replicating holographic gratings on a substrate
US7312090B2 (en) 2000-10-30 2007-12-25 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7327454B2 (en) 2000-10-30 2008-02-05 Srll Biosystems, Inc. Method and apparatus for detecting biomolecular interactions
US6951715B2 (en) 2000-10-30 2005-10-04 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7070987B2 (en) 2000-10-30 2006-07-04 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US8580578B2 (en) 2000-10-30 2013-11-12 X-Body, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic
US7422891B2 (en) 2000-10-30 2008-09-09 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7575939B2 (en) 2000-10-30 2009-08-18 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7611836B2 (en) 2000-10-30 2009-11-03 Sru Biosystems, Inc. Method of making a plastic colorimetric resonant biosensor device with liquid handling capabilities
US7615339B2 (en) 2000-10-30 2009-11-10 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US7718440B2 (en) 2000-10-30 2010-05-18 Sru Biosystems, Inc. Method and apparatus for biosensor spectral shift detection
US7875434B2 (en) 2000-10-30 2011-01-25 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7923239B2 (en) 2000-10-30 2011-04-12 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7023544B2 (en) 2000-10-30 2006-04-04 Sru Biosystems, Inc. Method and instrument for detecting biomolecular interactions
US7935520B2 (en) 2000-10-30 2011-05-03 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7435385B2 (en) 2000-10-30 2008-10-14 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US8247240B2 (en) 2000-10-30 2012-08-21 X-Body, Inc. Method and apparatus for biosensor spectral shift detection
US8202735B2 (en) 2002-09-09 2012-06-19 X-Body, Inc. Methods for screening cells and antibodies
US7927822B2 (en) 2002-09-09 2011-04-19 Sru Biosystems, Inc. Methods for screening cells and antibodies
US8551716B2 (en) 2002-09-09 2013-10-08 X-Body, Inc. Methods for screening cells and antibodies
US7429492B2 (en) 2002-09-09 2008-09-30 Sru Biosystems, Inc. Multiwell plates with integrated biosensors and membranes
US8298780B2 (en) 2003-09-22 2012-10-30 X-Body, Inc. Methods of detection of changes in cells
US9134307B2 (en) 2007-07-11 2015-09-15 X-Body, Inc. Method for determining ion channel modulating properties of a test reagent
US8257936B2 (en) 2008-04-09 2012-09-04 X-Body Inc. High resolution label free analysis of cellular properties
US8372592B2 (en) 2008-04-09 2013-02-12 X-Body, Inc. High resolution label free analysis of cellular properties

Also Published As

Publication number Publication date
JP2003515740A (ja) 2003-05-07
US20020171045A1 (en) 2002-11-21
JP5281222B2 (ja) 2013-09-04
FR2801977A1 (fr) 2001-06-08
WO2001040778A1 (fr) 2001-06-07
EP1234170A1 (fr) 2002-08-28
AU2181701A (en) 2001-06-12
US6893876B2 (en) 2005-05-17

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Year of fee payment: 17

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Effective date: 20170831