JP5275039B2 - 粉末の味覚遮蔽 - Google Patents

粉末の味覚遮蔽 Download PDF

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Publication number
JP5275039B2
JP5275039B2 JP2008546239A JP2008546239A JP5275039B2 JP 5275039 B2 JP5275039 B2 JP 5275039B2 JP 2008546239 A JP2008546239 A JP 2008546239A JP 2008546239 A JP2008546239 A JP 2008546239A JP 5275039 B2 JP5275039 B2 JP 5275039B2
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JP
Japan
Prior art keywords
solid
wax
coating
powder
drugs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2008546239A
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English (en)
Japanese (ja)
Other versions
JP2009521419A (ja
JP2009521419A5 (enExample
Inventor
ライナー・ベリングハウゼン
ダニエル・ルートハルト
フランク・リッダー
マルティン・シュタインベック
イェスコ・ツァンク
マルティン・ヴァイス
オラフ・ベーレント
ウド・ファン・スティップアウト
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Intellectual Property GmbH
Original Assignee
Bayer Intellectual Property GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Intellectual Property GmbH filed Critical Bayer Intellectual Property GmbH
Publication of JP2009521419A publication Critical patent/JP2009521419A/ja
Publication of JP2009521419A5 publication Critical patent/JP2009521419A5/ja
Application granted granted Critical
Publication of JP5275039B2 publication Critical patent/JP5275039B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Seasonings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2008546239A 2005-12-24 2006-12-20 粉末の味覚遮蔽 Expired - Fee Related JP5275039B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005062270.4 2005-12-24
DE102005062270A DE102005062270A1 (de) 2005-12-24 2005-12-24 Geschmacksmaskierung von Pulvern
PCT/EP2006/012284 WO2007073911A2 (de) 2005-12-24 2006-12-20 Geschmacksmaskierung von pulvern

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013042861A Division JP2013144695A (ja) 2005-12-24 2013-03-05 粉末の味覚遮蔽

Publications (3)

Publication Number Publication Date
JP2009521419A JP2009521419A (ja) 2009-06-04
JP2009521419A5 JP2009521419A5 (enExample) 2010-02-12
JP5275039B2 true JP5275039B2 (ja) 2013-08-28

Family

ID=38042692

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2008546239A Expired - Fee Related JP5275039B2 (ja) 2005-12-24 2006-12-20 粉末の味覚遮蔽
JP2013042861A Withdrawn JP2013144695A (ja) 2005-12-24 2013-03-05 粉末の味覚遮蔽

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013042861A Withdrawn JP2013144695A (ja) 2005-12-24 2013-03-05 粉末の味覚遮蔽

Country Status (24)

Country Link
US (1) US20090269411A1 (enExample)
EP (1) EP1968555A2 (enExample)
JP (2) JP5275039B2 (enExample)
KR (2) KR20080081021A (enExample)
CN (1) CN101346133A (enExample)
AU (1) AU2006331009B2 (enExample)
BR (1) BRPI0620618A2 (enExample)
CA (1) CA2634481A1 (enExample)
CR (1) CR10112A (enExample)
CU (1) CU23877B1 (enExample)
DE (1) DE102005062270A1 (enExample)
EC (1) ECSP088577A (enExample)
GT (1) GT200800126A (enExample)
HN (1) HN2008000964A (enExample)
IL (1) IL192085A0 (enExample)
MA (1) MA30072B1 (enExample)
MY (1) MY149601A (enExample)
NZ (1) NZ569279A (enExample)
RU (1) RU2440103C2 (enExample)
SV (1) SV2009002971A (enExample)
TN (1) TNSN08284A1 (enExample)
UA (1) UA93072C2 (enExample)
WO (1) WO2007073911A2 (enExample)
ZA (1) ZA200805498B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0327723D0 (en) 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
EP2050437A1 (en) * 2007-10-15 2009-04-22 Laboratoires SMB Improved pharmaceutical dry powder compositions for inhalation.
CA2714598A1 (en) * 2008-02-13 2009-08-20 Bayer Schering Pharma Aktiengesellschaft Drug delivery system with stabilising effect
US20110097405A1 (en) * 2008-02-13 2011-04-28 Bayer Schering Pharma Aktiengesellschaft Estradiol-containing drug delivery system
NZ593217A (en) * 2008-12-05 2013-05-31 Bayer Ip Gmbh Extrudate having spicular active substances
EP2411137B1 (en) 2009-03-27 2016-09-07 Bend Research, Inc. Spray-drying process
UY32836A (es) 2009-08-12 2011-03-31 Bayer Schering Pharma Ag Partículas estabilizadas que comprenden 5-metil-(6s)-tetrahidrofolato
EP2467126A1 (en) 2009-08-19 2012-06-27 Bayer Pharma Aktiengesellschaft Drug delivery systems (wafer) for pediatric use
US9084944B2 (en) 2010-09-03 2015-07-21 Bend Research, Inc. Spray-drying apparatus and methods of using the same
US8815294B2 (en) 2010-09-03 2014-08-26 Bend Research, Inc. Pharmaceutical compositions of dextran polymer derivatives and a carrier material
PT2611529T (pt) 2010-09-03 2019-05-09 Bend Res Inc Método de secagem por pulverização
KR101869114B1 (ko) 2010-09-20 2018-06-19 다이앤 골 마이크로캡슐화 방법 및 제품
WO2012040502A1 (en) 2010-09-24 2012-03-29 Bend Research, Inc. High-temperature spray drying process and apparatus
HU231017B1 (hu) 2012-05-08 2019-11-28 LAVET Gyógyszeripari Kft. Praziquantel tartalmú ízfedett formulációk
US8993041B2 (en) * 2012-10-15 2015-03-31 New Jersey Institute Of Technology Taste masked active pharmaceutical powder compositions and processes for making them
US11364203B2 (en) 2014-10-31 2022-06-21 Bend Reserch, Inc. Process for forming active domains dispersed in a matrix
CN114993892B (zh) * 2019-05-13 2024-10-18 南京制药厂有限公司 吡喹酮粒度的光散射检测法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568559A (en) * 1984-02-06 1986-02-04 Biotek, Inc. Composite core coated microparticles and process of preparing same
NL193682C (nl) * 1987-05-14 2000-07-04 Glaxo Group Ltd Beklede cefuroximaxetilsamenstelling.
CA2328080C (en) * 1998-04-09 2008-08-12 Eurand International S.P.A. Wettable microcapsules having hydrophobic polymer coated cores
FR2811913B1 (fr) * 2000-07-19 2003-09-19 Separex Sa Procede d'encapsulation sous forme de micro-capsules de fines particules solides
GB2405798A (en) * 2003-09-15 2005-03-16 Vectura Ltd Dry powder inhaler with primary and secondary piercing elements and a medicament pack for use with an inhalation device.

Also Published As

Publication number Publication date
UA93072C2 (ru) 2011-01-10
AU2006331009A1 (en) 2007-07-05
DE102005062270A1 (de) 2007-06-28
CU23877B1 (es) 2013-04-19
JP2013144695A (ja) 2013-07-25
KR20080081021A (ko) 2008-09-05
RU2440103C2 (ru) 2012-01-20
JP2009521419A (ja) 2009-06-04
MY149601A (en) 2013-09-13
SV2009002971A (es) 2009-04-28
BRPI0620618A2 (pt) 2011-11-16
AU2006331009B2 (en) 2012-10-04
KR101245627B1 (ko) 2013-03-20
US20090269411A1 (en) 2009-10-29
CA2634481A1 (en) 2007-07-05
ECSP088577A (es) 2008-07-30
CR10112A (es) 2009-01-07
EP1968555A2 (de) 2008-09-17
TNSN08284A1 (en) 2009-10-30
NZ569279A (en) 2011-06-30
CN101346133A (zh) 2009-01-14
WO2007073911A2 (de) 2007-07-05
HN2008000964A (es) 2013-03-11
CU20080124A7 (es) 2010-08-30
KR20120006085A (ko) 2012-01-17
ZA200805498B (en) 2009-11-25
IL192085A0 (en) 2008-12-29
GT200800126A (es) 2010-06-25
RU2008130171A (ru) 2010-01-27
WO2007073911A3 (de) 2007-08-23
MA30072B1 (fr) 2008-12-01

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