WO2007073911A3 - Geschmacksmaskierung von pulvern - Google Patents

Geschmacksmaskierung von pulvern Download PDF

Info

Publication number
WO2007073911A3
WO2007073911A3 PCT/EP2006/012284 EP2006012284W WO2007073911A3 WO 2007073911 A3 WO2007073911 A3 WO 2007073911A3 EP 2006012284 W EP2006012284 W EP 2006012284W WO 2007073911 A3 WO2007073911 A3 WO 2007073911A3
Authority
WO
WIPO (PCT)
Prior art keywords
powders
taste
masking
inhaled
production
Prior art date
Application number
PCT/EP2006/012284
Other languages
English (en)
French (fr)
Other versions
WO2007073911A2 (de
Inventor
Rainer Bellinghausen
Daniel Rudhardt
Frank Ridder
Martin Steinbeck
Jesko Zank
Martin Weiss
Olaf Behrend
Stiphout Udo Van
Original Assignee
Bayer Technology Services Gmbh
Rainer Bellinghausen
Daniel Rudhardt
Frank Ridder
Martin Steinbeck
Jesko Zank
Martin Weiss
Olaf Behrend
Stiphout Udo Van
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AU2006331009A priority Critical patent/AU2006331009B2/en
Application filed by Bayer Technology Services Gmbh, Rainer Bellinghausen, Daniel Rudhardt, Frank Ridder, Martin Steinbeck, Jesko Zank, Martin Weiss, Olaf Behrend, Stiphout Udo Van filed Critical Bayer Technology Services Gmbh
Priority to NZ569279A priority patent/NZ569279A/en
Priority to JP2008546239A priority patent/JP5275039B2/ja
Priority to KR1020117031078A priority patent/KR101245627B1/ko
Priority to EP06829765A priority patent/EP1968555A2/de
Priority to CA002634481A priority patent/CA2634481A1/en
Priority to BRPI0620618-2A priority patent/BRPI0620618A2/pt
Priority to US12/158,725 priority patent/US20090269411A1/en
Publication of WO2007073911A2 publication Critical patent/WO2007073911A2/de
Publication of WO2007073911A3 publication Critical patent/WO2007073911A3/de
Priority to IL192085A priority patent/IL192085A0/en
Priority to TNP2008000284A priority patent/TNSN08284A1/en
Priority to CU20080124A priority patent/CU23877B1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Seasonings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Die vorliegende Erfindung betrifft neue, geschmacksmaskierte Pulver zur Inhalation oder oralen Darreichung, ein einfaches Verfahren zu deren Herstellung und deren Verwendung zur Applikation von biologisch aktiven Stoffen.
PCT/EP2006/012284 2005-12-24 2006-12-20 Geschmacksmaskierung von pulvern WO2007073911A2 (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
CA002634481A CA2634481A1 (en) 2005-12-24 2006-12-20 Masking the taste of powders
NZ569279A NZ569279A (en) 2005-12-24 2006-12-20 Masking the taste of powders
JP2008546239A JP5275039B2 (ja) 2005-12-24 2006-12-20 粉末の味覚遮蔽
KR1020117031078A KR101245627B1 (ko) 2005-12-24 2006-12-20 산제의 맛 차단
EP06829765A EP1968555A2 (de) 2005-12-24 2006-12-20 Geschmacksmaskierung von pulvern
AU2006331009A AU2006331009B2 (en) 2005-12-24 2006-12-20 Masking the taste of powders
BRPI0620618-2A BRPI0620618A2 (pt) 2005-12-24 2006-12-20 sólido revestido para o mascaramento do sabor de pós, processo para preparação e uso do mesmo
US12/158,725 US20090269411A1 (en) 2005-12-24 2006-12-20 Masking the taste of powders
IL192085A IL192085A0 (en) 2005-12-24 2008-06-12 Masking the taste of powders
TNP2008000284A TNSN08284A1 (en) 2005-12-24 2008-06-23 Masking the taste of powders
CU20080124A CU23877B1 (es) 2005-12-24 2008-06-23 Enmascaramiento del sabor de polvos

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005062270A DE102005062270A1 (de) 2005-12-24 2005-12-24 Geschmacksmaskierung von Pulvern
DE102005062270.4 2005-12-24

Publications (2)

Publication Number Publication Date
WO2007073911A2 WO2007073911A2 (de) 2007-07-05
WO2007073911A3 true WO2007073911A3 (de) 2007-08-23

Family

ID=38042692

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/012284 WO2007073911A2 (de) 2005-12-24 2006-12-20 Geschmacksmaskierung von pulvern

Country Status (24)

Country Link
US (1) US20090269411A1 (de)
EP (1) EP1968555A2 (de)
JP (2) JP5275039B2 (de)
KR (2) KR101245627B1 (de)
CN (1) CN101346133A (de)
AU (1) AU2006331009B2 (de)
BR (1) BRPI0620618A2 (de)
CA (1) CA2634481A1 (de)
CR (1) CR10112A (de)
CU (1) CU23877B1 (de)
DE (1) DE102005062270A1 (de)
EC (1) ECSP088577A (de)
GT (1) GT200800126A (de)
HN (1) HN2008000964A (de)
IL (1) IL192085A0 (de)
MA (1) MA30072B1 (de)
MY (1) MY149601A (de)
NZ (1) NZ569279A (de)
RU (1) RU2440103C2 (de)
SV (1) SV2009002971A (de)
TN (1) TNSN08284A1 (de)
UA (1) UA93072C2 (de)
WO (1) WO2007073911A2 (de)
ZA (1) ZA200805498B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0327723D0 (en) 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
EP2050437A1 (de) * 2007-10-15 2009-04-22 Laboratoires SMB Verbesserte pharmazeutische Trockenpulverzusammensetzungen zur Inhalation
JP2011511823A (ja) * 2008-02-13 2011-04-14 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト エストラジオール含有薬物の送達システム
MX2010008945A (es) * 2008-02-13 2010-09-07 Bayer Schering Pharma Ag Sistema de administracion de drogas con efecto estabilizante.
PE20120182A1 (es) * 2008-12-05 2012-02-24 Bayer Ip Gmbh Extruidos con sustancias activas con forma de agujas
WO2010111132A2 (en) 2009-03-27 2010-09-30 Bend Research, Inc. Spray-drying process
UY32836A (es) 2009-08-12 2011-03-31 Bayer Schering Pharma Ag Partículas estabilizadas que comprenden 5-metil-(6s)-tetrahidrofolato
EP2467126A1 (de) 2009-08-19 2012-06-27 Bayer Pharma Aktiengesellschaft Wirkstofffreisetzungssysteme (wafer) für die pädiatrie
US8815294B2 (en) 2010-09-03 2014-08-26 Bend Research, Inc. Pharmaceutical compositions of dextran polymer derivatives and a carrier material
WO2012031133A2 (en) 2010-09-03 2012-03-08 Bench Research, Inc. Spray-drying apparatus and methods of using the same
EP2611529B1 (de) 2010-09-03 2019-01-23 Bend Research, Inc. Sprühtrocknungsverfahren
AU2011305572B2 (en) 2010-09-20 2016-08-04 Diane Goll Microencapsulation process and product
US9248584B2 (en) 2010-09-24 2016-02-02 Bend Research, Inc. High-temperature spray drying process and apparatus
HU231017B1 (hu) 2012-05-08 2019-11-28 LAVET Gyógyszeripari Kft. Praziquantel tartalmú ízfedett formulációk
US8993041B2 (en) * 2012-10-15 2015-03-31 New Jersey Institute Of Technology Taste masked active pharmaceutical powder compositions and processes for making them
US11364203B2 (en) 2014-10-31 2022-06-21 Bend Reserch, Inc. Process for forming active domains dispersed in a matrix

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2204792A (en) * 1987-05-14 1988-11-23 Glaxo Group Ltd Cefuroxime axetil compositions
WO1999052510A1 (en) * 1998-04-09 1999-10-21 Eurand International S.P.A. Wettable microcapsules having hydrophobic polymer coated cores

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568559A (en) * 1984-02-06 1986-02-04 Biotek, Inc. Composite core coated microparticles and process of preparing same
FR2811913B1 (fr) * 2000-07-19 2003-09-19 Separex Sa Procede d'encapsulation sous forme de micro-capsules de fines particules solides
GB2405798A (en) * 2003-09-15 2005-03-16 Vectura Ltd Dry powder inhaler with primary and secondary piercing elements and a medicament pack for use with an inhalation device.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2204792A (en) * 1987-05-14 1988-11-23 Glaxo Group Ltd Cefuroxime axetil compositions
WO1999052510A1 (en) * 1998-04-09 1999-10-21 Eurand International S.P.A. Wettable microcapsules having hydrophobic polymer coated cores

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PILLAI R S ET AL.: "Controlled dissolution from wax-coated aerosol particles in canine lungs", J. APPL. PHYSIOL., vol. 84, no. 2, 1998, pages 717 - 725, XP002435141 *

Also Published As

Publication number Publication date
MY149601A (en) 2013-09-13
DE102005062270A1 (de) 2007-06-28
TNSN08284A1 (en) 2009-10-30
RU2440103C2 (ru) 2012-01-20
HN2008000964A (es) 2013-03-11
GT200800126A (es) 2010-06-25
SV2009002971A (es) 2009-04-28
ECSP088577A (es) 2008-07-30
UA93072C2 (ru) 2011-01-10
CN101346133A (zh) 2009-01-14
JP5275039B2 (ja) 2013-08-28
KR101245627B1 (ko) 2013-03-20
RU2008130171A (ru) 2010-01-27
CU20080124A7 (es) 2010-08-30
AU2006331009B2 (en) 2012-10-04
EP1968555A2 (de) 2008-09-17
KR20080081021A (ko) 2008-09-05
KR20120006085A (ko) 2012-01-17
CR10112A (es) 2009-01-07
JP2009521419A (ja) 2009-06-04
IL192085A0 (en) 2008-12-29
AU2006331009A1 (en) 2007-07-05
US20090269411A1 (en) 2009-10-29
ZA200805498B (en) 2009-11-25
BRPI0620618A2 (pt) 2011-11-16
WO2007073911A2 (de) 2007-07-05
MA30072B1 (fr) 2008-12-01
NZ569279A (en) 2011-06-30
JP2013144695A (ja) 2013-07-25
CA2634481A1 (en) 2007-07-05
CU23877B1 (es) 2013-04-19

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