JP5206405B2 - イミダゾ［１，２−ａ］ピリジン誘導体：製造および医薬用途 - Google Patents

イミダゾ［１，２−ａ］ピリジン誘導体：製造および医薬用途 Download PDF

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JP5206405B2
JP5206405B2 JP2008502953A JP2008502953A JP5206405B2 JP 5206405 B2 JP5206405 B2 JP 5206405B2 JP 2008502953 A JP2008502953 A JP 2008502953A JP 2008502953 A JP2008502953 A JP 2008502953A JP 5206405 B2 JP5206405 B2 JP 5206405B2
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group
alkyl
aryl
optionally substituted
compound
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JP2008533198A (ja
JP2008533198A5 (https=
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リ，ケン・チ・リク
サン，エリック・ティー
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Lite Strategy Inc
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Mei Pharma Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A—HUMAN NECESSITIES
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P35/02—Antineoplastic agents specific for leukemia
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Transplantation (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
JP2008502953A 2005-03-21 2006-03-20 イミダゾ［１，２−ａ］ピリジン誘導体：製造および医薬用途 Expired - Fee Related JP5206405B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US66326505P 2005-03-21 2005-03-21
US60/663,265 2005-03-21
US75954406P 2006-01-18 2006-01-18
US60/759,544 2006-01-18
PCT/SG2006/000064 WO2006101455A1 (en) 2005-03-21 2006-03-20 Imidazo[1,2-a]pyridine derivatives: preparation and pharmaceutical applications

Publications (3)

Publication Number Publication Date
JP2008533198A JP2008533198A (ja) 2008-08-21
JP2008533198A5 JP2008533198A5 (https=) 2009-05-07
JP5206405B2 true JP5206405B2 (ja) 2013-06-12

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ID=37024054

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JP2008502953A Expired - Fee Related JP5206405B2 (ja) 2005-03-21 2006-03-20 イミダゾ［１，２−ａ］ピリジン誘導体：製造および医薬用途

Country Status (12)

Country Link
EP (1) EP1863811B1 (https=)
JP (1) JP5206405B2 (https=)
KR (1) KR101300831B1 (https=)
CN (1) CN101218238B (https=)
AR (1) AR056187A1 (https=)
AU (1) AU2006225355B2 (https=)
CA (1) CA2602328C (https=)
ES (1) ES2470766T3 (https=)
MX (1) MX2007011710A (https=)
MY (1) MY147647A (https=)
TW (1) TW200714600A (https=)
WO (1) WO2006101455A1 (https=)

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WO2008068392A1 (fr) * 2006-12-07 2008-06-12 Commissariat A L'energie Atomique Nouveaux derives fluorophores imidazo [1,2-a] pyridin-3-yl-amine et leur procede de preparation
WO2008124153A1 (en) 2007-04-10 2008-10-16 H. Lundbeck A/S Heteroaryl amide analogues as p2x7 antagonists
WO2008134553A1 (en) * 2007-04-26 2008-11-06 Xenon Pharmaceuticals Inc. Methods of using bicyclic compounds in treating sodium channel-mediated diseases
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WO2009019708A2 (en) * 2007-08-09 2009-02-12 Urifer Ltd Pharmaceutical compositions and methods for the treatment of cancer
DE102007040336A1 (de) 2007-08-27 2009-03-05 Johann Wolfgang Goethe-Universität Frankfurt am Main Neue Inhibitoren der 5-Lipoxygenase und deren Verwendungen
CN101918389A (zh) * 2007-11-02 2010-12-15 梅特希尔基因公司 组蛋白脱乙酰酶抑制剂
CA2724842A1 (en) * 2008-05-19 2009-11-26 Sunovion Pharmaceuticals Inc. Imidazo[1,2-a]pyridine compounds
EP2334675B1 (en) * 2008-09-16 2014-03-26 Csir Imidazopyridines and imidazopyrimidines as hiv-i reverse transcriptase inhibitors
WO2010043953A2 (en) * 2008-10-15 2010-04-22 Orchid Research Laboratories Ltd. Novel bridged cyclic compounds as histone deacetylase inhibitors
CN103140488A (zh) * 2010-08-03 2013-06-05 加利福尼亚大学董事会 缓和组织损伤和坏死的化合物和组合物
TW201242965A (en) 2011-02-01 2012-11-01 Kyowa Hakko Kirin Co Ltd Ring-fused heterocyclic derivative
EP2691392A1 (en) * 2011-03-31 2014-02-05 EMBLEM Technology Transfer GmbH Imidazo [1,2-a]pyridine compounds for use in therapy
US8883819B2 (en) 2011-09-01 2014-11-11 Irm Llc Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension
EP2881394B1 (en) * 2012-07-31 2018-03-21 Kyowa Hakko Kirin Co., Ltd. Condensed ring heterocyclic compound
US9073921B2 (en) 2013-03-01 2015-07-07 Novartis Ag Salt forms of bicyclic heterocyclic derivatives
MY169128A (en) * 2013-04-30 2019-02-18 Hoffmann La Roche Pd-catalyzed coupling of pyrazole amides
SG11201509650YA (en) * 2013-05-24 2015-12-30 Iomet Pharma Ltd Slc2a transporter inhibitors
WO2014209841A2 (en) * 2013-06-25 2014-12-31 F. Hoffmann-La Roche Ag Compounds for treating spinal muscular atrophy
EP3769757A3 (en) * 2013-10-18 2021-10-06 The General Hospital Corporation Imaging histone deacetylases with a radiotracer using positron emission tomography
US10723705B2 (en) 2015-08-14 2020-07-28 Incyte Corporation Heterocyclic compounds and uses thereof
KR101850062B1 (ko) * 2016-09-08 2018-04-19 가천대학교 산학협력단 신규 스피로퀴논 유도체 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 신경계 질환의 예방 또는 치료용 약학적 조성물
EP4019607B1 (en) 2020-12-22 2024-05-15 Essilor International Electrochromic compounds and optical articles containing them
CN113321651B (zh) * 2021-06-22 2022-06-14 四川省医学科学院·四川省人民医院 吡唑并吡啶异羟肟酸类化合物、其制备方法及其应用

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TW200714600A (en) 2007-04-16
EP1863811B1 (en) 2014-03-12
JP2008533198A (ja) 2008-08-21
AU2006225355B2 (en) 2010-12-09
KR20080005207A (ko) 2008-01-10
AU2006225355A1 (en) 2006-09-28
EP1863811A1 (en) 2007-12-12
CA2602328A1 (en) 2006-09-28
WO2006101455A1 (en) 2006-09-28
CN101218238B (zh) 2011-10-26
KR101300831B1 (ko) 2013-08-30
ES2470766T3 (es) 2014-06-24
AR056187A1 (es) 2007-09-26
MY147647A (en) 2012-12-31
EP1863811A4 (en) 2008-11-12
MX2007011710A (es) 2007-11-20
CN101218238A (zh) 2008-07-09
CA2602328C (en) 2014-07-29

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