JP5183479B2 - フェニル基を有するフェニル−［１，２，４］−オキサジアゾール−５−オン誘導体、その製造方法、及び医薬品としてのその使用 - Google Patents

フェニル基を有するフェニル−［１，２，４］−オキサジアゾール−５−オン誘導体、その製造方法、及び医薬品としてのその使用 Download PDF

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JP5183479B2
JP5183479B2 JP2008532648A JP2008532648A JP5183479B2 JP 5183479 B2 JP5183479 B2 JP 5183479B2 JP 2008532648 A JP2008532648 A JP 2008532648A JP 2008532648 A JP2008532648 A JP 2008532648A JP 5183479 B2 JP5183479 B2 JP 5183479B2
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Japan
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phenyl
alkyl
alkylene
trifluoromethyl
methyl
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Expired - Fee Related
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Japanese (ja)
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JP2009509989A (ja
JP2009509989A5 (https=
Inventor
シュテファーニエ・カイル
パトリック・ベルナルデリ
マティーアス・ウーアマン
ハンス・マター
ヴォルフガング・ヴェントラー
マイケ・グリエン
カレン・チャンドロス
ラン・リー
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Sanofi SA
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Sanofi SA
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
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    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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JP2008532648A 2005-09-29 2006-09-26 フェニル基を有するフェニル−［１，２，４］−オキサジアゾール−５−オン誘導体、その製造方法、及び医薬品としてのその使用 Expired - Fee Related JP5183479B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05021235 2005-09-29
EP05021235.6 2005-09-29
PCT/EP2006/009304 WO2007039178A2 (en) 2005-09-29 2006-09-26 Phenyl-[1,2,4]-oxadiazol-5-one derivatives with phenyl group, processes for their preparation and their use as pharmaceuticals

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JP2009509989A JP2009509989A (ja) 2009-03-12
JP2009509989A5 JP2009509989A5 (https=) 2009-11-05
JP5183479B2 true JP5183479B2 (ja) 2013-04-17

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JP2008532648A Expired - Fee Related JP5183479B2 (ja) 2005-09-29 2006-09-26 フェニル基を有するフェニル−［１，２，４］−オキサジアゾール−５−オン誘導体、その製造方法、及び医薬品としてのその使用
JP2008532645A Abandoned JP2009509986A (ja) 2005-09-29 2006-09-26 フェニル基を有する、フェニル−及びピリジル−１，２，４−オキサジアゾロン誘導体、その製造方法、及び医薬品としてのその使用

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JP2008532645A Abandoned JP2009509986A (ja) 2005-09-29 2006-09-26 フェニル基を有する、フェニル−及びピリジル−１，２，４−オキサジアゾロン誘導体、その製造方法、及び医薬品としてのその使用

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US (3) US7834030B2 (https=)
EP (2) EP1934206B1 (https=)
JP (2) JP5183479B2 (https=)
KR (2) KR20080048520A (https=)
CN (2) CN101268069A (https=)
AR (2) AR056541A1 (https=)
AT (1) ATE537167T1 (https=)
AU (2) AU2006299092A1 (https=)
BR (2) BRPI0616465A2 (https=)
CA (2) CA2624105C (https=)
CR (1) CR9784A (https=)
CY (1) CY1113376T1 (https=)
DK (1) DK1931660T3 (https=)
DO (2) DOP2006000204A (https=)
EC (1) ECSP088323A (https=)
ES (1) ES2392181T3 (https=)
IL (2) IL190228A0 (https=)
MA (2) MA29804B1 (https=)
MY (2) MY148982A (https=)
NO (2) NO20081367L (https=)
NZ (2) NZ566878A (https=)
PE (2) PE20070545A1 (https=)
PL (1) PL1931660T3 (https=)
PT (1) PT1931660E (https=)
RU (2) RU2008112201A (https=)
SI (1) SI1931660T1 (https=)
TN (1) TNSN08145A1 (https=)
TW (2) TWI398436B (https=)
UY (2) UY29830A1 (https=)
WO (2) WO2007039172A1 (https=)
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DE102007054497B3 (de) 2007-11-13 2009-07-23 Sanofi-Aventis Deutschland Gmbh Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
US10793515B2 (en) * 2008-03-19 2020-10-06 Aurimmed Pharma, Inc. Compounds advantageous in the treatment of central nervous system diseases and disorders
US20210130285A1 (en) * 2008-03-19 2021-05-06 Aurimmed Pharma, Inc. Novel compounds advantageous in the treatment of central nervous system diseases and disorders
WO2010003624A2 (en) 2008-07-09 2010-01-14 Sanofi-Aventis Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
MX2012001729A (es) 2009-08-26 2012-06-13 Sanofi Sa Nuevos hidratos cristalinos de fluoroglicosido heteroaromatico, productos farmaceuticos que comprenden estos compuestos, y su empleo.
WO2011107494A1 (de) 2010-03-03 2011-09-09 Sanofi Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
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WO2011157827A1 (de) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
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EP2683705B1 (de) 2011-03-08 2015-04-22 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8828995B2 (en) 2011-03-08 2014-09-09 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
WO2012120052A1 (de) 2011-03-08 2012-09-13 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8871758B2 (en) 2011-03-08 2014-10-28 Sanofi Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
EP2683699B1 (de) 2011-03-08 2015-06-24 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
EP2707367B1 (en) 2011-05-12 2019-10-09 Bionomics Limited Methods for preparing naphthyridines
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