JP5154432B2 - 三次元コンプレックスコイル - Google Patents
三次元コンプレックスコイル Download PDFInfo
- Publication number
- JP5154432B2 JP5154432B2 JP2008541466A JP2008541466A JP5154432B2 JP 5154432 B2 JP5154432 B2 JP 5154432B2 JP 2008541466 A JP2008541466 A JP 2008541466A JP 2008541466 A JP2008541466 A JP 2008541466A JP 5154432 B2 JP5154432 B2 JP 5154432B2
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- JP
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- Prior art keywords
- loop
- complex coil
- pattern
- complex
- coil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 238000000034 method Methods 0.000 claims description 22
- 238000004519 manufacturing process Methods 0.000 claims description 3
- 230000002792 vascular Effects 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 238000004804 winding Methods 0.000 description 17
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 14
- 239000000463 material Substances 0.000 description 6
- 229910052697 platinum Inorganic materials 0.000 description 6
- 206010002329 Aneurysm Diseases 0.000 description 4
- 239000000017 hydrogel Substances 0.000 description 4
- 229910052721 tungsten Inorganic materials 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 3
- 230000003902 lesion Effects 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 229920004934 Dacron® Polymers 0.000 description 2
- 201000008450 Intracranial aneurysm Diseases 0.000 description 2
- 229920000954 Polyglycolide Polymers 0.000 description 2
- 229910001260 Pt alloy Inorganic materials 0.000 description 2
- 208000007536 Thrombosis Diseases 0.000 description 2
- 229910001080 W alloy Inorganic materials 0.000 description 2
- 238000000137 annealing Methods 0.000 description 2
- 239000000560 biocompatible material Substances 0.000 description 2
- 229920002988 biodegradable polymer Polymers 0.000 description 2
- 239000004621 biodegradable polymer Substances 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000000919 ceramic Substances 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
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- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 229910001000 nickel titanium Inorganic materials 0.000 description 2
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 2
- 229920001778 nylon Polymers 0.000 description 2
- 229920000747 poly(lactic acid) Polymers 0.000 description 2
- 239000005020 polyethylene terephthalate Substances 0.000 description 2
- 239000004633 polyglycolic acid Substances 0.000 description 2
- 239000004626 polylactic acid Substances 0.000 description 2
- 229910001220 stainless steel Inorganic materials 0.000 description 2
- 239000010935 stainless steel Substances 0.000 description 2
- 229910052715 tantalum Inorganic materials 0.000 description 2
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 2
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 2
- 239000010937 tungsten Substances 0.000 description 2
- KHOITXIGCFIULA-UHFFFAOYSA-N Alophen Chemical compound C1=CC(OC(=O)C)=CC=C1C(C=1N=CC=CC=1)C1=CC=C(OC(C)=O)C=C1 KHOITXIGCFIULA-UHFFFAOYSA-N 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
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- 239000007943 implant Substances 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
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- 230000004048 modification Effects 0.000 description 1
- 235000020004 porter Nutrition 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
- B21F—WORKING OR PROCESSING OF METAL WIRE
- B21F45/00—Wire-working in the manufacture of other particular articles
- B21F45/008—Wire-working in the manufacture of other particular articles of medical instruments, e.g. stents, corneal rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/12145—Coils or wires having a pre-set deployed three-dimensional shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/1215—Coils or wires comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/1214—Coils or wires
- A61B17/12154—Coils or wires having stretch limiting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/12—Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12181—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
- A61B17/1219—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices expandable in contact with liquids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
- B21F—WORKING OR PROCESSING OF METAL WIRE
- B21F45/00—Wire-working in the manufacture of other particular articles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00526—Methods of manufacturing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Reproductive Health (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Mechanical Engineering (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73808705P | 2005-11-17 | 2005-11-17 | |
| US60/738,087 | 2005-11-17 | ||
| US82265606P | 2006-08-17 | 2006-08-17 | |
| US60/822,656 | 2006-08-17 | ||
| PCT/US2006/060923 WO2007076179A2 (en) | 2005-11-17 | 2006-11-15 | Three-dimensional complex coil |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012034653A Division JP2012120869A (ja) | 2005-11-17 | 2012-02-21 | 三次元コンプレックスコイル |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009516547A JP2009516547A (ja) | 2009-04-23 |
| JP2009516547A5 JP2009516547A5 (enExample) | 2012-06-14 |
| JP5154432B2 true JP5154432B2 (ja) | 2013-02-27 |
Family
ID=38218744
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008541466A Active JP5154432B2 (ja) | 2005-11-17 | 2006-11-15 | 三次元コンプレックスコイル |
| JP2012034653A Withdrawn JP2012120869A (ja) | 2005-11-17 | 2012-02-21 | 三次元コンプレックスコイル |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012034653A Withdrawn JP2012120869A (ja) | 2005-11-17 | 2012-02-21 | 三次元コンプレックスコイル |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US8066036B2 (enExample) |
| EP (1) | EP1973680B1 (enExample) |
| JP (2) | JP5154432B2 (enExample) |
| CN (1) | CN101394955B (enExample) |
| AU (1) | AU2006330786B2 (enExample) |
| CA (1) | CA2630021C (enExample) |
| WO (1) | WO2007076179A2 (enExample) |
Families Citing this family (251)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8425549B2 (en) | 2002-07-23 | 2013-04-23 | Reverse Medical Corporation | Systems and methods for removing obstructive matter from body lumens and treating vascular defects |
| US9675476B2 (en) | 2004-05-25 | 2017-06-13 | Covidien Lp | Vascular stenting for aneurysms |
| EP1750619B1 (en) | 2004-05-25 | 2013-07-24 | Covidien LP | Flexible vascular occluding device |
| EP2419048A4 (en) | 2004-05-25 | 2014-04-09 | Covidien Lp | VACCINE PLANTATION FOR ANEURYSMA |
| JP2009512515A (ja) | 2005-10-19 | 2009-03-26 | パルサー バスキュラー インコーポレイテッド | 脈管内をクリッピングし、腔内および組織欠損を修復するための方法およびシステム。 |
| WO2007100556A1 (en) | 2006-02-22 | 2007-09-07 | Ev3 Inc. | Embolic protection systems having radiopaque filter mesh |
| US10123803B2 (en) | 2007-10-17 | 2018-11-13 | Covidien Lp | Methods of managing neurovascular obstructions |
| US20100256600A1 (en) * | 2009-04-04 | 2010-10-07 | Ferrera David A | Neurovascular otw pta balloon catheter and delivery system |
| US20100174309A1 (en) * | 2008-05-19 | 2010-07-08 | Mindframe, Inc. | Recanalization/revascularization and embolus addressing systems including expandable tip neuro-microcatheter |
| US8066757B2 (en) * | 2007-10-17 | 2011-11-29 | Mindframe, Inc. | Blood flow restoration and thrombus management methods |
| US8088140B2 (en) | 2008-05-19 | 2012-01-03 | Mindframe, Inc. | Blood flow restorative and embolus removal methods |
| US9220522B2 (en) * | 2007-10-17 | 2015-12-29 | Covidien Lp | Embolus removal systems with baskets |
| US8926680B2 (en) * | 2007-11-12 | 2015-01-06 | Covidien Lp | Aneurysm neck bridging processes with revascularization systems methods and products thereby |
| US8585713B2 (en) | 2007-10-17 | 2013-11-19 | Covidien Lp | Expandable tip assembly for thrombus management |
| US9198687B2 (en) * | 2007-10-17 | 2015-12-01 | Covidien Lp | Acute stroke revascularization/recanalization systems processes and products thereby |
| US8968382B2 (en) * | 2007-12-11 | 2015-03-03 | Cornell University | Method and apparatus for restricting flow through an opening in the side wall |
| RU2506912C2 (ru) | 2008-02-22 | 2014-02-20 | Микро Терапьютикс, Инк. | Способы и устройство для восстановления потока |
| JP2011517607A (ja) | 2008-04-11 | 2011-06-16 | マインドフレーム, インコーポレイテッド | 脳卒中を処置する医療デバイスの送達のためのモノレール神経マイクロカテーテル、モノレール神経マイクロカテーテルによるプロセス、およびモノレール神経マイクロカテーテルによる製品 |
| ES2430117T3 (es) | 2008-04-21 | 2013-11-19 | Covidien Lp | Dispositivos embólicos de bola de trenza y sistemas de colocación |
| US10716573B2 (en) | 2008-05-01 | 2020-07-21 | Aneuclose | Janjua aneurysm net with a resilient neck-bridging portion for occluding a cerebral aneurysm |
| US10028747B2 (en) | 2008-05-01 | 2018-07-24 | Aneuclose Llc | Coils with a series of proximally-and-distally-connected loops for occluding a cerebral aneurysm |
| WO2009140437A1 (en) | 2008-05-13 | 2009-11-19 | Nfocus Neuromedical, Inc. | Braid implant delivery systems |
| US9402707B2 (en) | 2008-07-22 | 2016-08-02 | Neuravi Limited | Clot capture systems and associated methods |
| EP3903696A1 (en) | 2008-09-05 | 2021-11-03 | Pulsar Vascular, Inc. | Systems and methods for supporting or occluding a physiological opening or cavity |
| US9089405B1 (en) * | 2008-09-12 | 2015-07-28 | Microvention, Inc. | Three-dimensional complex coil |
| DK2387383T3 (en) | 2009-01-18 | 2017-07-10 | Ocon Medical Ltd | HOW TO UNKNOWN INTRAUTERIN DEVICE |
| JP5750051B2 (ja) * | 2009-01-22 | 2015-07-15 | コーネル ユニヴァーシティー | 管腔の壁を通過する流れを制限するための方法および装置 |
| US8409269B2 (en) | 2009-12-21 | 2013-04-02 | Covidien Lp | Procedures for vascular occlusion |
| US9358140B1 (en) | 2009-11-18 | 2016-06-07 | Aneuclose Llc | Stent with outer member to embolize an aneurysm |
| EP2613735B1 (en) | 2010-09-10 | 2018-05-09 | Covidien LP | Devices for the treatment of vascular defects |
| US8998947B2 (en) | 2010-09-10 | 2015-04-07 | Medina Medical, Inc. | Devices and methods for the treatment of vascular defects |
| ES2683943T3 (es) | 2010-10-22 | 2018-09-28 | Neuravi Limited | Sistema de captura y extirpación de coágulos |
| WO2012078678A1 (en) | 2010-12-06 | 2012-06-14 | Tyco Healthcare Group Lp | Vascular remodeling device |
| US11259824B2 (en) | 2011-03-09 | 2022-03-01 | Neuravi Limited | Clot retrieval device for removing occlusive clot from a blood vessel |
| US12076037B2 (en) | 2011-03-09 | 2024-09-03 | Neuravi Limited | Systems and methods to restore perfusion to a vessel |
| ES3029850T3 (en) | 2011-03-09 | 2025-06-25 | Neuravi Ltd | A clot retrieval device for removing occlusive clot from a blood vessel |
| US9089332B2 (en) | 2011-03-25 | 2015-07-28 | Covidien Lp | Vascular remodeling device |
| WO2012135859A2 (en) | 2011-04-01 | 2012-10-04 | Cornell University | Method and apparatus for restricting flow through an opening in the side wall of a body lumen, and/or for reinforcing a weakness in the side wall of a body lumen, while still maintaining substantially normal flow through the body lumen |
| AU2012253583B2 (en) | 2011-05-11 | 2014-09-25 | Covidien Lp | Vascular remodeling device |
| JP6157453B2 (ja) | 2011-05-11 | 2017-07-05 | マイクロベンション インコーポレイテッド | コイルパッキン |
| EP2713904B1 (en) | 2011-06-03 | 2018-01-10 | Pulsar Vascular, Inc. | Aneurysm devices with additional anchoring mechanisms and associated systems |
| US10779855B2 (en) | 2011-08-05 | 2020-09-22 | Route 92 Medical, Inc. | Methods and systems for treatment of acute ischemic stroke |
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| US9662704B2 (en) * | 2011-10-05 | 2017-05-30 | Marius S. Winograd | Method for forming a spiral support structure with continuous wire coil |
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| US9011480B2 (en) | 2012-01-20 | 2015-04-21 | Covidien Lp | Aneurysm treatment coils |
| US9615833B2 (en) * | 2012-06-29 | 2017-04-11 | Kaneka Corporation | Method for producing in-vivo indwelling member |
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| US9452070B2 (en) | 2012-10-31 | 2016-09-27 | Covidien Lp | Methods and systems for increasing a density of a region of a vascular device |
| CN108354645A (zh) | 2012-11-13 | 2018-08-03 | 柯惠有限合伙公司 | 封堵装置 |
| US10603157B2 (en) | 2013-03-13 | 2020-03-31 | DePuy Synthes Products, Inc. | Braid implant delivery and retraction device with distal engagement |
| US10561509B2 (en) | 2013-03-13 | 2020-02-18 | DePuy Synthes Products, Inc. | Braided stent with expansion ring and method of delivery |
| PL2967611T3 (pl) | 2013-03-14 | 2019-08-30 | Neuravi Limited | Urządzenie do usuwania ostrych blokad z naczyń krwionośnych |
| CN105208950A (zh) | 2013-03-14 | 2015-12-30 | 尼尔拉维有限公司 | 一种用于从血管去除堵塞凝块的凝块收取装置 |
| US9433429B2 (en) | 2013-03-14 | 2016-09-06 | Neuravi Limited | Clot retrieval devices |
| CN105142545B (zh) | 2013-03-15 | 2018-04-06 | 柯惠有限合伙公司 | 闭塞装置 |
| WO2014145012A2 (en) | 2013-03-15 | 2014-09-18 | Covidien Lp | Delivery and detachment mechanisms for vascular implants |
| US9795400B2 (en) | 2013-11-13 | 2017-10-24 | Covidien Lp | Galvanically assisted attachment of medical devices to thrombus |
| US20170000495A1 (en) * | 2013-12-18 | 2017-01-05 | Blockade Medical, LLC | Implant System and Delivery Method |
| JP6661539B2 (ja) | 2013-12-20 | 2020-03-11 | テルモ株式会社 | 血管閉鎖 |
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| US9918718B2 (en) | 2014-08-08 | 2018-03-20 | DePuy Synthes Products, Inc. | Embolic coil delivery system with retractable mechanical release mechanism |
| US10206796B2 (en) | 2014-08-27 | 2019-02-19 | DePuy Synthes Products, Inc. | Multi-strand implant with enhanced radiopacity |
| US9782178B2 (en) | 2014-09-19 | 2017-10-10 | DePuy Synthes Products, Inc. | Vasculature occlusion device detachment system with tapered corewire and heater activated fiber detachment |
| US11253278B2 (en) | 2014-11-26 | 2022-02-22 | Neuravi Limited | Clot retrieval system for removing occlusive clot from a blood vessel |
| US10617435B2 (en) | 2014-11-26 | 2020-04-14 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
| WO2016083472A1 (en) | 2014-11-26 | 2016-06-02 | Neuravi Limited | A clot retrieval device for removing occlusive clot from a blood vessel |
| US11065019B1 (en) | 2015-02-04 | 2021-07-20 | Route 92 Medical, Inc. | Aspiration catheter systems and methods of use |
| EP3253437B1 (en) | 2015-02-04 | 2019-12-04 | Route 92 Medical, Inc. | Rapid aspiration thrombectomy system |
| US10426497B2 (en) | 2015-07-24 | 2019-10-01 | Route 92 Medical, Inc. | Anchoring delivery system and methods |
| US10314593B2 (en) | 2015-09-23 | 2019-06-11 | Covidien Lp | Occlusive devices |
| US10478194B2 (en) | 2015-09-23 | 2019-11-19 | Covidien Lp | Occlusive devices |
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2006
- 2006-11-15 JP JP2008541466A patent/JP5154432B2/ja active Active
- 2006-11-15 AU AU2006330786A patent/AU2006330786B2/en active Active
- 2006-11-15 EP EP06848957.4A patent/EP1973680B1/en active Active
- 2006-11-15 WO PCT/US2006/060923 patent/WO2007076179A2/en not_active Ceased
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Also Published As
| Publication number | Publication date |
|---|---|
| CN101394955B (zh) | 2012-07-18 |
| WO2007076179A3 (en) | 2008-05-29 |
| US8066036B2 (en) | 2011-11-29 |
| CA2630021A1 (en) | 2007-07-05 |
| US20070175536A1 (en) | 2007-08-02 |
| JP2009516547A (ja) | 2009-04-23 |
| EP1973680A2 (en) | 2008-10-01 |
| US10081048B2 (en) | 2018-09-25 |
| US20120041464A1 (en) | 2012-02-16 |
| JP2012120869A (ja) | 2012-06-28 |
| EP1973680A4 (en) | 2015-03-25 |
| US20170072452A1 (en) | 2017-03-16 |
| CN101394955A (zh) | 2009-03-25 |
| US9533344B2 (en) | 2017-01-03 |
| EP1973680B1 (en) | 2018-01-10 |
| AU2006330786B2 (en) | 2012-02-02 |
| US10857589B2 (en) | 2020-12-08 |
| WO2007076179A2 (en) | 2007-07-05 |
| AU2006330786A1 (en) | 2007-07-05 |
| WO2007076179A9 (en) | 2007-08-23 |
| US20180354020A1 (en) | 2018-12-13 |
| CA2630021C (en) | 2013-08-13 |
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