JP5122980B2 - アルキルオキシ置換チアゾロキノリン類およびアルキルオキシ置換チアゾロナフチリデン類 - Google Patents
アルキルオキシ置換チアゾロキノリン類およびアルキルオキシ置換チアゾロナフチリデン類 Download PDFInfo
- Publication number
- JP5122980B2 JP5122980B2 JP2007555183A JP2007555183A JP5122980B2 JP 5122980 B2 JP5122980 B2 JP 5122980B2 JP 2007555183 A JP2007555183 A JP 2007555183A JP 2007555183 A JP2007555183 A JP 2007555183A JP 5122980 B2 JP5122980 B2 JP 5122980B2
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- compound
- het
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 0 *c(c1c2nc(*=C)[s]1)c(*)nc2N Chemical compound *c(c1c2nc(*=C)[s]1)c(*)nc2N 0.000 description 3
- SHEWPEGRZKMHAD-UHFFFAOYSA-N CCCc1nc(c(N)nc2c3ccc(OCCCCCCNC(OC(C)(C)C)=O)c2)c3[s]1 Chemical compound CCCc1nc(c(N)nc2c3ccc(OCCCCCCNC(OC(C)(C)C)=O)c2)c3[s]1 SHEWPEGRZKMHAD-UHFFFAOYSA-N 0.000 description 1
- PCNMVMAGJWTSBS-UHFFFAOYSA-N CCCc1nc(c(N)nc2c3ccc(OCCNC(OC(C)(C)C)=O)c2)c3[s]1 Chemical compound CCCc1nc(c(N)nc2c3ccc(OCCNC(OC(C)(C)C)=O)c2)c3[s]1 PCNMVMAGJWTSBS-UHFFFAOYSA-N 0.000 description 1
- UGXZMWDNPYXKQT-UHFFFAOYSA-N CCCc1nc(c(N)nc2c3ccc(OCCNS(C)(=O)=O)c2)c3[s]1 Chemical compound CCCc1nc(c(N)nc2c3ccc(OCCNS(C)(=O)=O)c2)c3[s]1 UGXZMWDNPYXKQT-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65158505P | 2005-02-09 | 2005-02-09 | |
| US60/651,585 | 2005-02-09 | ||
| US73303605P | 2005-11-03 | 2005-11-03 | |
| US60/733,036 | 2005-11-03 | ||
| PCT/US2006/004391 WO2006086449A2 (en) | 2005-02-09 | 2006-02-08 | Alkyloxy substituted thiazoloquinolines and thiazolonaphthyridines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008530099A JP2008530099A (ja) | 2008-08-07 |
| JP2008530099A5 JP2008530099A5 (enExample) | 2009-04-02 |
| JP5122980B2 true JP5122980B2 (ja) | 2013-01-16 |
Family
ID=36793669
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007555183A Expired - Fee Related JP5122980B2 (ja) | 2005-02-09 | 2006-02-08 | アルキルオキシ置換チアゾロキノリン類およびアルキルオキシ置換チアゾロナフチリデン類 |
Country Status (7)
| Country | Link |
|---|---|
| US (4) | US20080318998A1 (enExample) |
| EP (1) | EP1846419B1 (enExample) |
| JP (1) | JP5122980B2 (enExample) |
| AU (1) | AU2006212765B2 (enExample) |
| CA (1) | CA2597324C (enExample) |
| ES (1) | ES2475728T3 (enExample) |
| WO (1) | WO2006086449A2 (enExample) |
Families Citing this family (61)
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| US6797718B2 (en) | 2002-06-07 | 2004-09-28 | 3M Innovative Properties Company | Ether substituted imidazopyridines |
| US20040265351A1 (en) | 2003-04-10 | 2004-12-30 | Miller Richard L. | Methods and compositions for enhancing immune response |
| AU2004266658A1 (en) | 2003-08-12 | 2005-03-03 | 3M Innovative Properties Company | Hydroxylamine substituted imidazo-containing compounds |
| US7897597B2 (en) | 2003-08-27 | 2011-03-01 | 3M Innovative Properties Company | Aryloxy and arylalkyleneoxy substituted imidazoquinolines |
| JP2007504269A (ja) | 2003-09-05 | 2007-03-01 | スリーエム イノベイティブ プロパティズ カンパニー | Cd5+b細胞リンパ腫の治療方法 |
| US8871782B2 (en) | 2003-10-03 | 2014-10-28 | 3M Innovative Properties Company | Alkoxy substituted imidazoquinolines |
| US7544697B2 (en) | 2003-10-03 | 2009-06-09 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and analogs thereof |
| AU2004315876B2 (en) | 2003-10-03 | 2011-05-26 | 3M Innovative Properties Company | Pyrazolopyridines and analogs thereof |
| EP1682544A4 (en) | 2003-11-14 | 2009-05-06 | 3M Innovative Properties Co | HYDROXYLAMINE SUBSTITUTED IMIDAZO RING COMPOUNDS |
| AU2004291101A1 (en) | 2003-11-14 | 2005-06-02 | 3M Innovative Properties Company | Oxime substituted imidazo ring compounds |
| AU2004293078B2 (en) | 2003-11-25 | 2012-01-19 | 3M Innovative Properties Company | Substituted imidazo ring systems and methods |
| EP1701955A1 (en) | 2003-12-29 | 2006-09-20 | 3M Innovative Properties Company | Arylalkenyl and arylalkynyl substituted imidazoquinolines |
| EP1699788A2 (en) | 2003-12-30 | 2006-09-13 | 3M Innovative Properties Company | Imidazoquinolinyl, imidazopyridinyl and imidazonaphthyridinyl sulfonamides |
| EP1730143A2 (en) | 2004-03-24 | 2006-12-13 | 3M Innovative Properties Company | Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines |
| US8017779B2 (en) | 2004-06-15 | 2011-09-13 | 3M Innovative Properties Company | Nitrogen containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines |
| US8541438B2 (en) | 2004-06-18 | 2013-09-24 | 3M Innovative Properties Company | Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines |
| US7897609B2 (en) | 2004-06-18 | 2011-03-01 | 3M Innovative Properties Company | Aryl substituted imidazonaphthyridines |
| WO2006065280A2 (en) | 2004-06-18 | 2006-06-22 | 3M Innovative Properties Company | Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods |
| US8026366B2 (en) | 2004-06-18 | 2011-09-27 | 3M Innovative Properties Company | Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines |
| WO2006028962A2 (en) | 2004-09-02 | 2006-03-16 | 3M Innovative Properties Company | 1-alkoxy 1h-imidazo ring systems and methods |
| AU2005322898B2 (en) | 2004-12-30 | 2011-11-24 | 3M Innovative Properties Company | Chiral fused (1,2)imidazo(4,5-c) ring compounds |
| US8034938B2 (en) | 2004-12-30 | 2011-10-11 | 3M Innovative Properties Company | Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds |
| WO2006084251A2 (en) | 2005-02-04 | 2006-08-10 | Coley Pharmaceutical Group, Inc. | Aqueous gel formulations containing immune reponse modifiers |
| CA2597324C (en) | 2005-02-09 | 2015-06-30 | Coley Pharmaceutical Group, Inc. | Alkyloxy substituted thiazoloquinolines and thiazolonaphthyridines |
| EP1877056A2 (en) | 2005-02-09 | 2008-01-16 | Coley Pharmaceutical Group, Inc. | Oxime and hydroxylamine substituted thiazoloý4,5-c¨ring compounds and methods |
| AU2006213746A1 (en) | 2005-02-11 | 2006-08-17 | Coley Pharmaceutical Group, Inc. | Oxime and hydroxylamine substituted imidazo(4,5-c) ring compounds and methods |
| EP1845988A2 (en) | 2005-02-11 | 2007-10-24 | 3M Innovative Properties Company | Substituted imidazoquinolines and imidazonaphthyridines |
| JP2008531567A (ja) | 2005-02-23 | 2008-08-14 | コーリー ファーマシューティカル グループ,インコーポレイテッド | ヒドロキシアルキル置換イミダゾキノリン化合物および方法 |
| WO2006091647A2 (en) | 2005-02-23 | 2006-08-31 | Coley Pharmaceutical Group, Inc. | Method of preferentially inducing the biosynthesis of interferon |
| EP1851224A2 (en) | 2005-02-23 | 2007-11-07 | 3M Innovative Properties Company | Hydroxyalkyl substituted imidazoquinolines |
| CA2602683A1 (en) | 2005-04-01 | 2006-10-12 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridine-1,4-diamines and analogs thereof |
| AU2006232375A1 (en) | 2005-04-01 | 2006-10-12 | Coley Pharmaceutical Group, Inc. | 1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases |
| ZA200803029B (en) | 2005-09-09 | 2009-02-25 | Coley Pharm Group Inc | Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods |
| AU2006287270A1 (en) | 2005-09-09 | 2007-03-15 | Coley Pharmaceutical Group, Inc. | Amide and carbamate derivatives of N-{2-[4-amino-2- (ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-1,1-dimethylethyl}methanesulfonamide and methods |
| EP1948173B1 (en) | 2005-11-04 | 2013-07-17 | 3M Innovative Properties Company | Hydroxy and alkoxy substituted 1h-imidazoquinolines and methods |
| US8951528B2 (en) | 2006-02-22 | 2015-02-10 | 3M Innovative Properties Company | Immune response modifier conjugates |
| WO2007106854A2 (en) | 2006-03-15 | 2007-09-20 | Coley Pharmaceutical Group, Inc. | Hydroxy and alkoxy substituted 1h-imidazonaphthyridines and methods |
| WO2008008432A2 (en) | 2006-07-12 | 2008-01-17 | Coley Pharmaceutical Group, Inc. | Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods |
| US8178539B2 (en) | 2006-09-06 | 2012-05-15 | 3M Innovative Properties Company | Substituted 3,4,6,7-tetrahydro-5H-1,2a,4a,8-tetraazacyclopenta[cd]phenalenes and methods |
| US20080149123A1 (en) | 2006-12-22 | 2008-06-26 | Mckay William D | Particulate material dispensing hairbrush with combination bristles |
| JP5333454B2 (ja) * | 2008-11-06 | 2013-11-06 | 日産化学工業株式会社 | 液晶配向処理剤 |
| CN103800906B (zh) | 2009-03-25 | 2017-09-22 | 德克萨斯大学系统董事会 | 用于刺激哺乳动物对病原体的先天免疫抵抗力的组合物 |
| RS55819B1 (sr) | 2010-08-17 | 2017-08-31 | 3M Innovative Properties Co | Kompozicije sa lipidiranim modifikatorom imuno-odgovora, formulacije, i postupci |
| MX355623B (es) | 2011-06-03 | 2018-04-25 | 3M Innovative Properties Co | Hidrazino-1h-imidazoquinolin-4-aminas y conjugados elaborados a partir de las mismas. |
| MX347240B (es) | 2011-06-03 | 2017-04-20 | 3M Innovative Properties Co | Ligadores heterobifuncionales con segmentos polietilenglicol y conjugados modificadores de la respuesta inmunitaria elaborados a partir de los mismos. |
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- 2006-02-08 WO PCT/US2006/004391 patent/WO2006086449A2/en not_active Ceased
- 2006-02-08 US US11/884,052 patent/US20080318998A1/en not_active Abandoned
- 2006-02-08 AU AU2006212765A patent/AU2006212765B2/en not_active Ceased
-
2015
- 2015-06-08 US US14/732,815 patent/US9546184B2/en not_active Expired - Fee Related
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2016
- 2016-12-12 US US15/375,316 patent/US20170088559A1/en not_active Abandoned
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2017
- 2017-11-02 US US15/801,448 patent/US20180057509A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006212765A1 (en) | 2006-08-17 |
| AU2006212765B2 (en) | 2012-02-02 |
| WO2006086449A3 (en) | 2007-07-05 |
| ES2475728T3 (es) | 2014-07-11 |
| US20150266901A1 (en) | 2015-09-24 |
| CA2597324A1 (en) | 2006-08-17 |
| EP1846419A2 (en) | 2007-10-24 |
| US9546184B2 (en) | 2017-01-17 |
| EP1846419B1 (en) | 2014-04-16 |
| EP1846419A4 (en) | 2010-07-07 |
| US20170088559A1 (en) | 2017-03-30 |
| US20080318998A1 (en) | 2008-12-25 |
| JP2008530099A (ja) | 2008-08-07 |
| CA2597324C (en) | 2015-06-30 |
| WO2006086449A2 (en) | 2006-08-17 |
| US20180057509A1 (en) | 2018-03-01 |
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