JP5070043B2 - プロバイオティックバクテリアを含む経口投与剤 - Google Patents

プロバイオティックバクテリアを含む経口投与剤 Download PDF

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Publication number
JP5070043B2
JP5070043B2 JP2007513729A JP2007513729A JP5070043B2 JP 5070043 B2 JP5070043 B2 JP 5070043B2 JP 2007513729 A JP2007513729 A JP 2007513729A JP 2007513729 A JP2007513729 A JP 2007513729A JP 5070043 B2 JP5070043 B2 JP 5070043B2
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Japan
Prior art keywords
lactobacillus
agent according
oral administration
coating
administration agent
Prior art date
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Expired - Fee Related
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JP2007513729A
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English (en)
Japanese (ja)
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JP2008500294A5 (cg-RX-API-DMAC10.html
JP2008500294A (ja
Inventor
マルクス ルドルフ
シュテファン ヘンケ
イリス マネック
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Merck Patent GmbH
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Merck Patent GmbH
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Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of JP2008500294A publication Critical patent/JP2008500294A/ja
Publication of JP2008500294A5 publication Critical patent/JP2008500294A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2007513729A 2004-05-28 2005-05-04 プロバイオティックバクテリアを含む経口投与剤 Expired - Fee Related JP5070043B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102004026706.5 2004-05-28
DE102004026706A DE102004026706A1 (de) 2004-05-28 2004-05-28 Orale Darreichungsform enthaltend probiotische Bakterien
PCT/EP2005/004835 WO2005117921A1 (de) 2004-05-28 2005-05-04 Orale darreichungsform enthaltend probiotische bakterien

Publications (3)

Publication Number Publication Date
JP2008500294A JP2008500294A (ja) 2008-01-10
JP2008500294A5 JP2008500294A5 (cg-RX-API-DMAC10.html) 2008-06-26
JP5070043B2 true JP5070043B2 (ja) 2012-11-07

Family

ID=34980007

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007513729A Expired - Fee Related JP5070043B2 (ja) 2004-05-28 2005-05-04 プロバイオティックバクテリアを含む経口投与剤

Country Status (20)

Country Link
US (2) US20090162322A1 (cg-RX-API-DMAC10.html)
EP (1) EP1753440B1 (cg-RX-API-DMAC10.html)
JP (1) JP5070043B2 (cg-RX-API-DMAC10.html)
KR (1) KR101289413B1 (cg-RX-API-DMAC10.html)
CN (1) CN1956724B (cg-RX-API-DMAC10.html)
AT (1) ATE386534T1 (cg-RX-API-DMAC10.html)
AU (1) AU2005249187B2 (cg-RX-API-DMAC10.html)
BR (1) BRPI0511615B8 (cg-RX-API-DMAC10.html)
CA (1) CA2568171C (cg-RX-API-DMAC10.html)
CY (1) CY1107399T1 (cg-RX-API-DMAC10.html)
DE (2) DE102004026706A1 (cg-RX-API-DMAC10.html)
DK (1) DK1753440T3 (cg-RX-API-DMAC10.html)
ES (1) ES2299034T3 (cg-RX-API-DMAC10.html)
MX (1) MXPA06013686A (cg-RX-API-DMAC10.html)
PL (1) PL1753440T3 (cg-RX-API-DMAC10.html)
PT (1) PT1753440E (cg-RX-API-DMAC10.html)
RU (1) RU2376023C2 (cg-RX-API-DMAC10.html)
SI (1) SI1753440T1 (cg-RX-API-DMAC10.html)
WO (1) WO2005117921A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA200610768B (cg-RX-API-DMAC10.html)

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EP1885207B1 (en) * 2005-05-18 2011-07-06 DSM IP Assets B.V. Compositions for enteral application of microorganisms
US9084434B2 (en) 2006-09-27 2015-07-21 Little Calumet Holdings Llc Probiotic oral dosage forms
DK2068899T3 (da) * 2006-10-02 2015-09-28 Dupont Nutrition Biosci Aps Lactobacillus acidophilus til anvendelse til reducering af forekomsten og varigheden af luftvejsinfektioner
WO2010114864A1 (en) * 2009-04-01 2010-10-07 Little Calumet Holdings, Llc Probiotic oral dosage forms
EP2464721B1 (en) 2009-08-14 2015-10-21 DuPont Nutrition Biosciences ApS Coated dehydrated microorganisms with enhanced stability and viability
WO2011111783A1 (ja) 2010-03-12 2011-09-15 カルピス株式会社 大腸におけるビフィズス菌の増加及び減少抑制剤
US9585922B2 (en) 2011-05-06 2017-03-07 Organobalance Medical Ag Lactic acid bacteria that co-aggregate with pathogenic bacteria
US9308227B2 (en) 2011-05-16 2016-04-12 Organobalance Medical Ag Lactic acid bacteria and compositions containing them against bacterial colds
ITMI20120131A1 (it) * 2012-02-01 2013-08-02 Probiotical Spa Batteri probiotici microincapsulati multistrato, loro produzione ed uso
EP2830599B1 (en) 2012-03-29 2018-08-15 Therabiome, Llc Gastrointestinal site-specific oral vaccination formulations active on the ileum and appendix
RU2491079C1 (ru) * 2012-07-13 2013-08-27 Федеральное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) Комплексный пробиотический препарат и способ его получения
TWI481409B (zh) * 2013-01-10 2015-04-21 Conmed Pharmaceutical & Bio Medical Corp 一種使用益生菌製備用於清除尿毒素之組合物的用途
US9907755B2 (en) 2013-03-14 2018-03-06 Therabiome, Llc Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents
US10849940B2 (en) * 2013-06-10 2020-12-01 Brock M. Lundberg Prebiotics of highly refined cellulose
KR101470995B1 (ko) * 2013-08-30 2014-12-09 주식회사 바이오리쏘스 프로피온산 생산능을 갖는 미생물 및 그를 포함하는 조사료 조성물
EP3164145A4 (en) 2014-07-01 2018-01-17 Probi Usa, Inc. Bi-layer dual release probiotic tablets
ES2575828B1 (es) * 2014-12-31 2017-07-07 Universidad De León Empleo de probióticos en el incremento de la fertilidad masculina
US10339273B2 (en) 2015-11-18 2019-07-02 Warsaw Orthopedic, Inc. Systems and methods for pre-operative procedure determination and outcome predicting
CN111870617B (zh) * 2019-11-04 2022-06-10 深圳碳云智能数字生命健康管理有限公司 肠道益生菌补剂配方的确定方法、装置、存储介质及处理器
CN111110703B (zh) * 2020-01-13 2020-12-01 华中农业大学 动物双歧杆菌及其制备的复合菌制剂在制备治疗或预防禽流感病毒感染的药物中的应用
KR102769334B1 (ko) * 2021-10-20 2025-02-14 경희대학교 산학협력단 대변 미생물총을 포함하는 가축 증체용 조성물
CN114917259B (zh) * 2022-02-15 2023-10-13 中国科学院上海硅酸盐研究所 一种二维氢硅烯-微生物复合材料及其制备方法和应用
TWI857740B (zh) * 2023-08-09 2024-10-01 統一企業股份有限公司 複合益生菌粉及其用途以及益生菌組合物

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58157726A (ja) * 1982-03-11 1983-09-19 Shin Etsu Chem Co Ltd 固形薬剤用腸溶性コ−テイング剤組成物
JPH024016A (ja) * 1988-06-20 1990-01-09 Fujitsu Ltd 半導体集積回路
JPH0441434A (ja) * 1990-06-07 1992-02-12 Asahi Breweries Ltd 腸溶性コーティングを施した乳酸菌錠剤
US5160742A (en) * 1991-12-31 1992-11-03 Abbott Laboratories System for delivering an active substance for sustained release
IT1265092B1 (it) * 1993-05-31 1996-10-30 Giuliani Spa Preparato per uso come integratore alimentare, o dietetico,a rilascio mirato nel colon
US5733568A (en) * 1993-12-03 1998-03-31 Lafor Laboratories Limited Micro-encapsulated lactobacilli for medical applications
US5482718A (en) * 1994-03-23 1996-01-09 Hoffmann-La Roche Inc. Colon-targeted delivery system
US6168806B1 (en) * 1999-03-05 2001-01-02 Fang-Yu Lee Orally administrable nifedipine pellet and process for the preparation thereof
EP1072258A1 (de) * 1999-07-28 2001-01-31 Greither, Peter Eine Kapsel für die Freisetzung von Bakterien, enthaltend ein Bakterienlyophilisat und ein Verfahren zu ihrer Herstellung
DE19937361A1 (de) * 1999-08-12 2001-02-22 Merck Patent Gmbh Orale Darreichungsform
CN1156271C (zh) * 2000-04-29 2004-07-07 中国科学技术大学 一种固体药剂用高分子包衣粉及其制备方法
RU2171672C1 (ru) * 2000-08-31 2001-08-10 Московская медицинская академия им. И.М. Сеченова Способ получения микрокапсулированных форм лактобактерий
US6749867B2 (en) * 2000-11-29 2004-06-15 Joseph R. Robinson Delivery system for omeprazole and its salts
US20020160048A1 (en) * 2001-02-15 2002-10-31 Karoline Bechtold-Peters Medical formulation containing a muscarinic agonist
BR0207948A (pt) * 2001-03-09 2004-07-27 Produits Nestel S A Soc D Composição que melhora os déficits fisiológicos relacionados com a idade e que aumenta a longevidade
US7101565B2 (en) * 2002-02-05 2006-09-05 Corpak Medsystems, Inc. Probiotic/prebiotic composition and delivery method
US20040001817A1 (en) * 2002-05-14 2004-01-01 Giampapa Vincent C. Anti-aging nutritional supplement
US20050266069A1 (en) * 2002-09-06 2005-12-01 Simmons Donald L Stable probiotic microsphere compositions and their methods of preparation

Also Published As

Publication number Publication date
CY1107399T1 (el) 2012-12-19
US20190110997A1 (en) 2019-04-18
BRPI0511615B1 (pt) 2018-01-23
PL1753440T3 (pl) 2008-05-30
RU2006145056A (ru) 2008-07-10
BRPI0511615B8 (pt) 2021-05-25
BRPI0511615A (pt) 2008-01-02
AU2005249187A1 (en) 2005-12-15
ATE386534T1 (de) 2008-03-15
DK1753440T3 (da) 2008-06-02
EP1753440B1 (de) 2008-02-20
ZA200610768B (en) 2008-07-30
ES2299034T3 (es) 2008-05-16
SI1753440T1 (sl) 2008-08-31
CA2568171A1 (en) 2005-12-15
MXPA06013686A (es) 2007-02-13
CN1956724B (zh) 2013-08-28
CN1956724A (zh) 2007-05-02
KR20070024539A (ko) 2007-03-02
EP1753440A1 (de) 2007-02-21
AU2005249187B2 (en) 2011-03-17
RU2376023C2 (ru) 2009-12-20
KR101289413B1 (ko) 2013-08-07
CA2568171C (en) 2013-09-17
DE102004026706A1 (de) 2005-12-15
US20090162322A1 (en) 2009-06-25
PT1753440E (pt) 2008-05-28
WO2005117921A1 (de) 2005-12-15
JP2008500294A (ja) 2008-01-10
DE502005002929D1 (de) 2008-04-03

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