JP5064630B2 - 薬草組成物ｐｈｙ９０６および化学療法におけるその使用 - Google Patents

薬草組成物ｐｈｙ９０６および化学療法におけるその使用 Download PDF

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JP5064630B2
JP5064630B2 JP2001564775A JP2001564775A JP5064630B2 JP 5064630 B2 JP5064630 B2 JP 5064630B2 JP 2001564775 A JP2001564775 A JP 2001564775A JP 2001564775 A JP2001564775 A JP 2001564775A JP 5064630 B2 JP5064630 B2 JP 5064630B2
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phy906
cpt
chemotherapeutic
treatment
mice
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JP2004500390A5 (enExample
JP2004500390A (ja
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ヤン−チー チェン，
シュー−フエイ リュー，
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エール ユニヴァーシティ
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2001564775A 2000-03-09 2001-03-08 薬草組成物ｐｈｙ９０６および化学療法におけるその使用 Expired - Lifetime JP5064630B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52205500A 2000-03-09 2000-03-09
US09/522,055 2000-03-09
PCT/US2001/007353 WO2001066123A2 (en) 2000-03-09 2001-03-08 Composition consisting of phy906 and chemotherapeutic agents

Related Child Applications (1)

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JP2012095816A Division JP2012167101A (ja) 2000-03-09 2012-04-19 薬草組成物ｐｈｙ９０６および化学療法におけるその使用

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JP2004500390A JP2004500390A (ja) 2004-01-08
JP2004500390A5 JP2004500390A5 (enExample) 2010-05-27
JP5064630B2 true JP5064630B2 (ja) 2012-10-31

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JP2001564775A Expired - Lifetime JP5064630B2 (ja) 2000-03-09 2001-03-08 薬草組成物ｐｈｙ９０６および化学療法におけるその使用
JP2012095816A Pending JP2012167101A (ja) 2000-03-09 2012-04-19 薬草組成物ｐｈｙ９０６および化学療法におけるその使用
JP2014136932A Pending JP2014208684A (ja) 2000-03-09 2014-07-02 薬草組成物ｐｈｙ９０６および化学療法におけるその使用

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JP2014136932A Pending JP2014208684A (ja) 2000-03-09 2014-07-02 薬草組成物ｐｈｙ９０６および化学療法におけるその使用

Country Status (13)

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US (1) US7025993B2 (enExample)
EP (1) EP1401458B1 (enExample)
JP (3) JP5064630B2 (enExample)
KR (1) KR100840213B1 (enExample)
CN (1) CN100490845C (enExample)
AT (1) ATE494899T1 (enExample)
AU (1) AU4550801A (enExample)
CA (1) CA2402466C (enExample)
DE (1) DE60143857D1 (enExample)
DK (1) DK1401458T3 (enExample)
ES (1) ES2358639T3 (enExample)
TW (1) TWI324069B (enExample)
WO (1) WO2001066123A2 (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
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WO2009152228A2 (en) * 2008-06-10 2009-12-17 Yale University Use of the combination of phy906 and a tyrosine kinase inhibitor as a cancer treatment regimen
US7534455B2 (en) * 2000-03-09 2009-05-19 Yale University Herbal composition PHY906 and its use in chemotherapy
WO2008101079A1 (en) 2007-02-15 2008-08-21 Yale University Herbal-composition phy906 and its use in chemotherapy
EP1487434B1 (en) * 2002-03-06 2007-05-09 The Medical Research and Education Trust Botanical extract compositions with anti-cancer activity comprising isoliquiritigenin
RU2209062C1 (ru) * 2002-03-19 2003-07-27 Институт физиологии им. И.П.Павлова РАН Вещество, обладающее седативным действием
WO2005077370A1 (ja) * 2004-02-13 2005-08-25 Kabushiki Kaisha Yakult Honsha カンプトテシン類含有水溶液製剤
EP2987495A1 (en) 2007-10-25 2016-02-24 Yale University Use of phy906 as treatment for inflammatory bowel disease and/or irritable bowel syndrome
WO2009067103A1 (en) * 2007-11-20 2009-05-28 Hewlett-Packard Development Company, L.P. Liquid handling device
KR100915457B1 (ko) * 2008-01-31 2009-09-04 세종대학교산학협력단 한국산 겨우살이 추출물이 함유된 미세캡슐을 유효성분으로포함하는 기능성 식품
TWI366466B (en) * 2008-05-08 2012-06-21 Ind Tech Res Inst Herbal extracts capable of inducing immune cells to produce interferon and activating toll-like receptors and the preparation thereof
US8574636B2 (en) * 2008-09-25 2013-11-05 Lifebiotic Medical Research Ltd Herbal formulations
KR101138461B1 (ko) * 2010-02-12 2012-04-26 한국생명공학연구원 감초 추출물을 포함하는 로타바이러스 감염의 예방 또는 치료용 조성물
US8541382B2 (en) 2010-11-13 2013-09-24 Sirbal Ltd. Cardiac glycoside analogs in combination with emodin for cancer therapy
US8597695B1 (en) 2010-11-13 2013-12-03 Sirbal Ltd. Herbal combinations for treatment of a skin condition
US9066974B1 (en) 2010-11-13 2015-06-30 Sirbal Ltd. Molecular and herbal combinations for treating psoriasis
US9095606B1 (en) 2010-11-13 2015-08-04 Sirbal Ltd. Molecular and herbal combinations for treating psoriasis
US20170049835A1 (en) 2015-07-29 2017-02-23 Sirbal Ltd. Herbal Combinations For Treating Scalp Conditions
CN102716421A (zh) * 2012-06-21 2012-10-10 中国人民解放军第三军医大学第一附属医院 治疗扁平疣的中药口服液及其制备方法
CN102698068B (zh) * 2012-07-02 2013-07-24 张秀香 一种预防化疗所致口腔黏膜炎的口腔护理液制备方法
KR101350143B1 (ko) 2013-05-30 2014-01-16 재단법인 통합의료진흥원 반하 및 황금 생약 추출물을 포함하는 항암제로 인한 부작용의 경감용 조성물
WO2015082950A1 (en) 2013-12-02 2015-06-11 Sirbal Ltd. Herbal combinations for treatment of a skin condition
JP2018523674A (ja) 2015-08-21 2018-08-23 ザ メソディスト ホスピタル 腸カルボキシルエステラーゼ２酵素活性を選択的に阻害するための組成物及び方法
CN114668839A (zh) * 2016-05-23 2022-06-28 耶鲁大学 包含phy906提取物、黄芩提取物或来自这些提取物的化合物的联合疗法
RU2762986C2 (ru) * 2016-06-22 2021-12-24 Йейл Юниверсити Основанный на механизме контроль качества лекарственного средства растительного происхождения
EP3760215A4 (en) * 2018-02-28 2022-01-12 Chung Ang University Industry Academic Cooperation Foundation COMPOSITION FOR THE PREVENTION, RELIEF OR TREATMENT OF CACHEXIA AND MUSCLE WASTING
WO2019204471A1 (en) * 2018-04-20 2019-10-24 Yale University Treatment of hepatitis c
WO2020255133A1 (en) * 2019-06-18 2020-12-24 The Cures Ltd. Novel therapeutic preparations comprising scutellaria barbata
CN111011136B (zh) * 2019-11-13 2021-11-02 云南中烟新材料科技有限公司 一种假秦艽的人工种植方法
US20220339233A1 (en) * 2019-12-09 2022-10-27 Yale University Compositions and methods for preventing recurrence of cancer
EP4125801A4 (en) * 2020-03-30 2024-05-15 Yale University METHODS OF TREATMENT OF INFLAMMATORY AND FIBROTIC DISEASES AND DISORDERS
CN114642732A (zh) * 2020-12-21 2022-06-21 苏州普瑞森生物科技有限公司 一种组合物及其在制备治疗肿瘤的药物中的应用
CN116712507B (zh) * 2023-08-10 2023-10-20 中国人民解放军总医院第六医学中心 一种辅助乳腺癌化疗的中药组合物及其制备方法、应用

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JPS5936619A (ja) 1982-08-23 1984-02-28 Tsumura Juntendo Inc 制癌補助剤
JPS5936621A (ja) 1982-08-25 1984-02-28 Tsumura Juntendo Inc 脂肪分解促進作用阻害剤
DE69030321T2 (de) 1989-11-03 1998-01-15 Alexander S Sun Phytotherapie von krebs
US5665393A (en) 1996-09-03 1997-09-09 International Medical Research, Inc. Herbal composition for treating prostate carcinoma
US6048847A (en) 1997-09-30 2000-04-11 Dabur Research Foundation Use of betulinic acid and its derivatives for inhibiting cancer growth and a method of monitoring this

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CA2402466C (en) 2014-11-18
KR20020086627A (ko) 2002-11-18
US7025993B2 (en) 2006-04-11
ES2358639T3 (es) 2011-05-12
WO2001066123A3 (en) 2004-01-08
JP2004500390A (ja) 2004-01-08
CA2402466A1 (en) 2001-09-13
AU4550801A (en) 2001-09-17
US20030211180A1 (en) 2003-11-13
EP1401458A2 (en) 2004-03-31
CN1612743A (zh) 2005-05-04
KR100840213B1 (ko) 2008-06-23
ATE494899T1 (de) 2011-01-15
EP1401458B1 (en) 2011-01-12
WO2001066123A2 (en) 2001-09-13
DE60143857D1 (de) 2011-02-24
JP2012167101A (ja) 2012-09-06
JP2014208684A (ja) 2014-11-06
CN100490845C (zh) 2009-05-27
TWI324069B (en) 2010-05-01
DK1401458T3 (da) 2011-05-09

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