DK1401458T3 - Sammensætning bestående af PHY906 og kemoterapeutiske midler - Google Patents
Sammensætning bestående af PHY906 og kemoterapeutiske midlerInfo
- Publication number
- DK1401458T3 DK1401458T3 DK01918429.0T DK01918429T DK1401458T3 DK 1401458 T3 DK1401458 T3 DK 1401458T3 DK 01918429 T DK01918429 T DK 01918429T DK 1401458 T3 DK1401458 T3 DK 1401458T3
- Authority
- DK
- Denmark
- Prior art keywords
- phy906
- chemotherapy
- chemotherapeutic agents
- composition consisting
- disease
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 239000009820 PHY 906 Substances 0.000 title abstract 2
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 229940127089 cytotoxic agent Drugs 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 238000002512 chemotherapy Methods 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 231100001274 therapeutic index Toxicity 0.000 abstract 2
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 229940044683 chemotherapy drug Drugs 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52205500A | 2000-03-09 | 2000-03-09 | |
| PCT/US2001/007353 WO2001066123A2 (en) | 2000-03-09 | 2001-03-08 | Composition consisting of phy906 and chemotherapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1401458T3 true DK1401458T3 (da) | 2011-05-09 |
Family
ID=24079273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01918429.0T DK1401458T3 (da) | 2000-03-09 | 2001-03-08 | Sammensætning bestående af PHY906 og kemoterapeutiske midler |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7025993B2 (enExample) |
| EP (1) | EP1401458B1 (enExample) |
| JP (3) | JP5064630B2 (enExample) |
| KR (1) | KR100840213B1 (enExample) |
| CN (1) | CN100490845C (enExample) |
| AT (1) | ATE494899T1 (enExample) |
| AU (1) | AU4550801A (enExample) |
| CA (1) | CA2402466C (enExample) |
| DE (1) | DE60143857D1 (enExample) |
| DK (1) | DK1401458T3 (enExample) |
| ES (1) | ES2358639T3 (enExample) |
| TW (1) | TWI324069B (enExample) |
| WO (1) | WO2001066123A2 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7534455B2 (en) * | 2000-03-09 | 2009-05-19 | Yale University | Herbal composition PHY906 and its use in chemotherapy |
| US8871279B2 (en) | 2000-03-09 | 2014-10-28 | Yale University | Use of the combination of PHY906 and a tyrosine kinase inhibitor as a cancer treatment regimen |
| AU2003217982A1 (en) * | 2002-03-06 | 2003-09-22 | The Medical Research And Education Trust | Botanical extract compositions with anti-cancer or phytoestrogenic activity comprising wogonin, isoliquiritigenin and/or coumestrol |
| RU2209062C1 (ru) * | 2002-03-19 | 2003-07-27 | Институт физиологии им. И.П.Павлова РАН | Вещество, обладающее седативным действием |
| EP1714653B1 (en) * | 2004-02-13 | 2010-11-24 | Kabushiki Kaisha Yakult Honsha | Aqueous solution preparation containing a camptothecin |
| CN101730535A (zh) | 2007-02-15 | 2010-06-09 | 耶鲁大学 | 草药组合物phy906及其在化疗中的用途 |
| CN101918017B (zh) * | 2007-10-25 | 2013-07-31 | 植物药学公司 | Phy906用于治疗炎性肠病和/或肠易激综合征的用途 |
| US9778276B2 (en) * | 2007-11-20 | 2017-10-03 | Hewlett-Packard Development Company, L.P. | Liquid handling device |
| KR100915457B1 (ko) * | 2008-01-31 | 2009-09-04 | 세종대학교산학협력단 | 한국산 겨우살이 추출물이 함유된 미세캡슐을 유효성분으로포함하는 기능성 식품 |
| TWI366466B (en) * | 2008-05-08 | 2012-06-21 | Ind Tech Res Inst | Herbal extracts capable of inducing immune cells to produce interferon and activating toll-like receptors and the preparation thereof |
| EP2341918B1 (en) | 2008-09-25 | 2018-02-28 | Life Biotech Medical Research Ltd | Herbal formulations |
| KR101138461B1 (ko) * | 2010-02-12 | 2012-04-26 | 한국생명공학연구원 | 감초 추출물을 포함하는 로타바이러스 감염의 예방 또는 치료용 조성물 |
| US8734859B1 (en) | 2010-11-13 | 2014-05-27 | Sirbal Ltd. | Molecular combinations for cancer or other disease treatment |
| US8541382B2 (en) | 2010-11-13 | 2013-09-24 | Sirbal Ltd. | Cardiac glycoside analogs in combination with emodin for cancer therapy |
| US9095606B1 (en) | 2010-11-13 | 2015-08-04 | Sirbal Ltd. | Molecular and herbal combinations for treating psoriasis |
| US9066974B1 (en) | 2010-11-13 | 2015-06-30 | Sirbal Ltd. | Molecular and herbal combinations for treating psoriasis |
| US20170049687A1 (en) | 2015-07-29 | 2017-02-23 | Sirbal Ltd. | Herbal Combinations For Treating Scalp Conditions |
| CN102716421A (zh) * | 2012-06-21 | 2012-10-10 | 中国人民解放军第三军医大学第一附属医院 | 治疗扁平疣的中药口服液及其制备方法 |
| CN102698068B (zh) * | 2012-07-02 | 2013-07-24 | 张秀香 | 一种预防化疗所致口腔黏膜炎的口腔护理液制备方法 |
| KR101350143B1 (ko) * | 2013-05-30 | 2014-01-16 | 재단법인 통합의료진흥원 | 반하 및 황금 생약 추출물을 포함하는 항암제로 인한 부작용의 경감용 조성물 |
| WO2015082950A1 (en) | 2013-12-02 | 2015-06-11 | Sirbal Ltd. | Herbal combinations for treatment of a skin condition |
| CA2995575A1 (en) * | 2015-08-21 | 2017-03-02 | The Methodist Hospital | Compositions and methods for selectively inhibiting intestinal carboxylesterase 2 enzyme activity |
| CA3024301A1 (en) * | 2016-05-23 | 2017-11-30 | Yale University | Improved therapeutic index of anti-immune checkpoint inhibitors using combination therapy comprising a phy906 extract, a scutellaria baicalensis georgi (s) extract or a compound from such extracts |
| SG11201901540UA (en) * | 2016-06-22 | 2019-04-29 | Univ Yale | Mechanism based quality control for botanical medicine |
| KR102166949B1 (ko) | 2018-02-28 | 2020-10-16 | 중앙대학교 산학협력단 | 악액질 및 근손실 예방, 개선 또는 치료용 조성물 |
| US20190314431A1 (en) * | 2018-04-14 | 2019-10-17 | Jianyi Zhang | Method of Discovery of Potential Bioactive Compounds in Herbals by Regrouping after Chromatography |
| WO2019204471A1 (en) * | 2018-04-20 | 2019-10-24 | Yale University | Treatment of hepatitis c |
| WO2020255133A1 (en) * | 2019-06-18 | 2020-12-24 | The Cures Ltd. | Novel therapeutic preparations comprising scutellaria barbata |
| CN111011136B (zh) * | 2019-11-13 | 2021-11-02 | 云南中烟新材料科技有限公司 | 一种假秦艽的人工种植方法 |
| JP2023504202A (ja) * | 2019-12-09 | 2023-02-01 | イエール ユニバーシティ | がんの再発を予防するための組成物および方法 |
| TW202200183A (zh) * | 2020-03-30 | 2022-01-01 | 耶魯大學 | 治療炎性和纖維化疾病和病症的方法 |
| CN114642732A (zh) * | 2020-12-21 | 2022-06-21 | 苏州普瑞森生物科技有限公司 | 一种组合物及其在制备治疗肿瘤的药物中的应用 |
| TW202337484A (zh) * | 2022-03-01 | 2023-10-01 | 耶魯大學 | 用於調節t細胞之活化t細胞核因子（nfat）活性的組成物及方法 |
| CN116712507B (zh) * | 2023-08-10 | 2023-10-20 | 中国人民解放军总医院第六医学中心 | 一种辅助乳腺癌化疗的中药组合物及其制备方法、应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5936619A (ja) | 1982-08-23 | 1984-02-28 | Tsumura Juntendo Inc | 制癌補助剤 |
| JPS5936621A (ja) | 1982-08-25 | 1984-02-28 | Tsumura Juntendo Inc | 脂肪分解促進作用阻害剤 |
| DK0500739T3 (da) | 1989-11-03 | 1997-04-14 | Alexander S Sun | Urtebehandling af malignitet |
| US5665393A (en) | 1996-09-03 | 1997-09-09 | International Medical Research, Inc. | Herbal composition for treating prostate carcinoma |
| US6048847A (en) | 1997-09-30 | 2000-04-11 | Dabur Research Foundation | Use of betulinic acid and its derivatives for inhibiting cancer growth and a method of monitoring this |
-
2001
- 2001-03-08 TW TW090105449A patent/TWI324069B/zh not_active IP Right Cessation
- 2001-03-08 US US10/220,876 patent/US7025993B2/en not_active Expired - Lifetime
- 2001-03-08 AT AT01918429T patent/ATE494899T1/de not_active IP Right Cessation
- 2001-03-08 WO PCT/US2001/007353 patent/WO2001066123A2/en not_active Ceased
- 2001-03-08 CN CNB018081975A patent/CN100490845C/zh not_active Expired - Lifetime
- 2001-03-08 AU AU4550801A patent/AU4550801A/xx active Pending
- 2001-03-08 KR KR1020027011817A patent/KR100840213B1/ko not_active Expired - Lifetime
- 2001-03-08 DK DK01918429.0T patent/DK1401458T3/da active
- 2001-03-08 CA CA2402466A patent/CA2402466C/en not_active Expired - Lifetime
- 2001-03-08 EP EP01918429A patent/EP1401458B1/en not_active Expired - Lifetime
- 2001-03-08 JP JP2001564775A patent/JP5064630B2/ja not_active Expired - Lifetime
- 2001-03-08 ES ES01918429T patent/ES2358639T3/es not_active Expired - Lifetime
- 2001-03-08 DE DE60143857T patent/DE60143857D1/de not_active Expired - Lifetime
-
2012
- 2012-04-19 JP JP2012095816A patent/JP2012167101A/ja active Pending
-
2014
- 2014-07-02 JP JP2014136932A patent/JP2014208684A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012167101A (ja) | 2012-09-06 |
| EP1401458A2 (en) | 2004-03-31 |
| KR100840213B1 (ko) | 2008-06-23 |
| CN100490845C (zh) | 2009-05-27 |
| DE60143857D1 (de) | 2011-02-24 |
| ATE494899T1 (de) | 2011-01-15 |
| WO2001066123A2 (en) | 2001-09-13 |
| US7025993B2 (en) | 2006-04-11 |
| CA2402466C (en) | 2014-11-18 |
| AU4550801A (en) | 2001-09-17 |
| CA2402466A1 (en) | 2001-09-13 |
| WO2001066123A3 (en) | 2004-01-08 |
| JP2004500390A (ja) | 2004-01-08 |
| TWI324069B (en) | 2010-05-01 |
| JP5064630B2 (ja) | 2012-10-31 |
| CN1612743A (zh) | 2005-05-04 |
| JP2014208684A (ja) | 2014-11-06 |
| KR20020086627A (ko) | 2002-11-18 |
| US20030211180A1 (en) | 2003-11-13 |
| ES2358639T3 (es) | 2011-05-12 |
| EP1401458B1 (en) | 2011-01-12 |
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