JP5010281B2 - Epcamに対する二重特異性抗体を含む薬学的組成物 - Google Patents

Epcamに対する二重特異性抗体を含む薬学的組成物 Download PDF

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JP5010281B2
JP5010281B2 JP2006529930A JP2006529930A JP5010281B2 JP 5010281 B2 JP5010281 B2 JP 5010281B2 JP 2006529930 A JP2006529930 A JP 2006529930A JP 2006529930 A JP2006529930 A JP 2006529930A JP 5010281 B2 JP5010281 B2 JP 5010281B2
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pharmaceutical composition
epcam
acid sequence
cells
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JP2007530435A5 (enExample
JP2007530435A (ja
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ペーター クファー
メーラ ベリー
ソニア オフナー
クラウス ブリスクウェイン
アンドレアス ウォルフ
トビアス ラウム
ブライト コールエイゼン
ウラ レンケリ−シュッツ
パトリック ボエール
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マイクロメット アクツィエン ゲゼルシャフト
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    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3076Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
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    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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    • C07K2319/00Fusion polypeptide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit

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JP2006529930A 2003-05-31 2004-05-26 Epcamに対する二重特異性抗体を含む薬学的組成物 Expired - Lifetime JP5010281B2 (ja)

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EP03012134.7 2003-05-31
EP03012134 2003-05-31
EP03012133.9 2003-05-31
EP03012133 2003-05-31
PCT/EP2004/005687 WO2004106383A1 (en) 2003-05-31 2004-05-26 Pharmaceutical composition comprising a bispecific antibody for epcam

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JP2007530435A JP2007530435A (ja) 2007-11-01
JP2007530435A5 JP2007530435A5 (enExample) 2011-02-03
JP5010281B2 true JP5010281B2 (ja) 2012-08-29

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US (2) US7919089B2 (enExample)
EP (1) EP1629013B1 (enExample)
JP (1) JP5010281B2 (enExample)
KR (1) KR20060015602A (enExample)
AU (1) AU2004242847B2 (enExample)
BR (1) BRPI0410338A (enExample)
CA (1) CA2522894C (enExample)
NZ (1) NZ543202A (enExample)
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Cited By (1)

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US8513417B2 (en) 2007-01-31 2013-08-20 Kyushu University, National University Corporation Method for synthesis of nitroxyl radical

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