JP4949038B2 - 免疫組織化学的検出のための方法および組成物 - Google Patents

免疫組織化学的検出のための方法および組成物 Download PDF

Info

Publication number
JP4949038B2
JP4949038B2 JP2006541492A JP2006541492A JP4949038B2 JP 4949038 B2 JP4949038 B2 JP 4949038B2 JP 2006541492 A JP2006541492 A JP 2006541492A JP 2006541492 A JP2006541492 A JP 2006541492A JP 4949038 B2 JP4949038 B2 JP 4949038B2
Authority
JP
Japan
Prior art keywords
antibody
polymer
poly
dextran
linked
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2006541492A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007513334A (ja
JP2007513334A5 (enExample
Inventor
ウィンザー,ラーズ
クノール,アンソニー,ライオネル
ウェックワース,ケリー,アン
ロブボーグ,ウフェ
Original Assignee
ダコ デンマーク アクティーゼルスカブ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34657207&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP4949038(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by ダコ デンマーク アクティーゼルスカブ filed Critical ダコ デンマーク アクティーゼルスカブ
Publication of JP2007513334A publication Critical patent/JP2007513334A/ja
Publication of JP2007513334A5 publication Critical patent/JP2007513334A5/ja
Application granted granted Critical
Publication of JP4949038B2 publication Critical patent/JP4949038B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2474/00Immunochemical assays or immunoassays characterised by detection mode or means of detection
    • G01N2474/20Immunohistochemistry assay

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2006541492A 2003-12-01 2004-11-30 免疫組織化学的検出のための方法および組成物 Expired - Lifetime JP4949038B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US52596003P 2003-12-01 2003-12-01
US60/525,960 2003-12-01
US57080004P 2004-05-14 2004-05-14
US60/570,800 2004-05-14
PCT/US2004/039911 WO2005054860A1 (en) 2003-12-01 2004-11-30 Methods and compositions for immuno-histochemical detection

Publications (3)

Publication Number Publication Date
JP2007513334A JP2007513334A (ja) 2007-05-24
JP2007513334A5 JP2007513334A5 (enExample) 2008-01-17
JP4949038B2 true JP4949038B2 (ja) 2012-06-06

Family

ID=34657207

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006541492A Expired - Lifetime JP4949038B2 (ja) 2003-12-01 2004-11-30 免疫組織化学的検出のための方法および組成物

Country Status (6)

Country Link
US (1) US8632994B2 (enExample)
EP (1) EP1697750B1 (enExample)
JP (1) JP4949038B2 (enExample)
AU (1) AU2004295699A1 (enExample)
CA (1) CA2544577C (enExample)
WO (1) WO2005054860A1 (enExample)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE46351E1 (en) 2001-05-10 2017-03-28 Battelle Energy Alliance, Llc Antibody profiling sensitivity through increased reporter antibody layering
US6989276B2 (en) 2001-05-10 2006-01-24 Battelle Energy Alliance, Llc Rapid classification of biological components
US20050186642A1 (en) * 2004-02-24 2005-08-25 Biocare Medical, Inc. Immunoassay reagents and methods of use thereof
WO2007031874A2 (en) * 2005-07-01 2007-03-22 Dako Denmark A/S Method of simultaneously visualizing multiple biological targets
EP1984738A2 (en) 2006-01-11 2008-10-29 Raindance Technologies, Inc. Microfluidic devices and methods of use in the formation and control of nanoreactors
US20090061478A1 (en) * 2006-01-30 2009-03-05 Lene Have Poulsen High-Speed Quantification of Antigen Specific T-Cells in Whole Blood by Flow Cytometry
WO2007133710A2 (en) 2006-05-11 2007-11-22 Raindance Technologies, Inc. Microfluidic devices and methods of use thereof
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
EP2095117A2 (en) * 2006-12-01 2009-09-02 Dako Denmark A/S Systems and methods for biological and chemical detection, comprising automatic selection of reagent sets
JP5241100B2 (ja) * 2006-12-28 2013-07-17 シスメックス株式会社 抗原賦活化液、抗原賦活化方法及び細胞の検出方法
US8772046B2 (en) 2007-02-06 2014-07-08 Brandeis University Manipulation of fluids and reactions in microfluidic systems
WO2008116468A2 (en) 2007-03-26 2008-10-02 Dako Denmark A/S Mhc peptide complexes and uses thereof in infectious diseases
WO2008130623A1 (en) 2007-04-19 2008-10-30 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
GB0707870D0 (en) * 2007-04-23 2007-05-30 Selected Antibodies Ltd Assay Devices and Methods and Components for use Therein
US20080286881A1 (en) * 2007-05-14 2008-11-20 Apel William A Compositions and methods for combining report antibodies
WO2009003493A2 (en) 2007-07-03 2009-01-08 Dako Denmark A/S Mhc multimers, methods for their generation, labeling and use
US10611818B2 (en) 2007-09-27 2020-04-07 Agilent Technologies, Inc. MHC multimers in tuberculosis diagnostics, vaccine and therapeutics
US10968269B1 (en) 2008-02-28 2021-04-06 Agilent Technologies, Inc. MHC multimers in borrelia diagnostics and disease
WO2009120893A2 (en) * 2008-03-28 2009-10-01 The Regents Of The University Of California Polypeptide-polymer conjugates and methods of use thereof
JP2009244109A (ja) * 2008-03-31 2009-10-22 Japan Advanced Institute Of Science & Technology Hokuriku 標識物質
US12038438B2 (en) 2008-07-18 2024-07-16 Bio-Rad Laboratories, Inc. Enzyme quantification
WO2010009365A1 (en) 2008-07-18 2010-01-21 Raindance Technologies, Inc. Droplet libraries
WO2010009735A2 (en) * 2008-07-23 2010-01-28 Dako Denmark A/S Combinatorial analysis and repair
GB0817244D0 (en) * 2008-09-20 2008-10-29 Univ Cardiff Use of a protein kinase inhibitor to detect immune cells, such as T cells
US11992518B2 (en) 2008-10-02 2024-05-28 Agilent Technologies, Inc. Molecular vaccines for infectious disease
WO2010037402A1 (en) 2008-10-02 2010-04-08 Dako Denmark A/S Molecular vaccines for infectious disease
JP5749171B2 (ja) * 2008-10-30 2015-07-15 ルクセンブルグ・インスティテュート・オブ・ヘルス バイオマーカー
US8435735B2 (en) * 2009-02-19 2013-05-07 Dako Denmark A/S Methods and compounds for detection of molecular targets
WO2010101931A2 (en) * 2009-03-03 2010-09-10 Access Medical System Co., Ltd. Detection system and method for high sensitivity fluorescent assays
US8528589B2 (en) 2009-03-23 2013-09-10 Raindance Technologies, Inc. Manipulation of microfluidic droplets
EP2281632B1 (en) 2009-07-02 2013-11-13 Amic AB Capillary driven assay device and its manufacture
US9410965B2 (en) * 2009-09-17 2016-08-09 Battelle Energy Alliance, Llc Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual
US8969009B2 (en) * 2009-09-17 2015-03-03 Vicki S. Thompson Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual
JP5853703B2 (ja) * 2010-02-02 2016-02-09 コニカミノルタ株式会社 アナライト検出プローブ、アナライト検出試薬およびこれを用いたアナライトの検出方法
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
EP4484577A3 (en) 2010-02-12 2025-03-26 Bio-Rad Laboratories, Inc. Digital analyte analysis
EP2388324A1 (de) * 2010-05-20 2011-11-23 Siemens Healthcare Diagnostics Inc. Kontrollmaterial für Nukleinsäureteste
US9150852B2 (en) 2011-02-18 2015-10-06 Raindance Technologies, Inc. Compositions and methods for molecular labeling
US8852592B2 (en) 2011-05-10 2014-10-07 Biocare Medical, Llc Systems and methods for anti-PAX8 antibodies
EP3709018A1 (en) 2011-06-02 2020-09-16 Bio-Rad Laboratories, Inc. Microfluidic apparatus for identifying components of a chemical reaction
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
DE102011053541A1 (de) * 2011-09-12 2013-03-14 Nanospot Gmbh Marker zum optischen Nachweis der Bindung eines Biomoleküls und Verfahren zur Anwendung des Markers
US10316103B1 (en) 2012-03-30 2019-06-11 Biocare Medical, Llc Systems and methods for anti-Uroplakin III antibodies
US9429577B2 (en) 2012-09-27 2016-08-30 Biocare Medical, Llc Anti-uroplakin II antibodies systems and methods
WO2014100220A2 (en) 2012-12-18 2014-06-26 Biocare Medical, Llc Antibody cocktail systems and methods for classification of histologic subtypes in lung cancer
DK2962113T3 (da) 2013-02-28 2019-07-01 Biocare Medical Llc Systemer og fremgangsmåder med anti-p40-antistoffer
EP3052522B1 (en) 2013-10-03 2019-12-11 Biocare Medical, LLC Anti-sox10 antibody systems and methods
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
US10634590B2 (en) 2014-03-11 2020-04-28 Emd Millipore Corporation IHC, tissue slide fluid exchange disposable and system
BR112016024624B1 (pt) * 2014-04-23 2023-10-24 Nichirei Biosciences Inc. Produto de combinação para detectar marcador alvo, método para detectar um marcador alvo em uma amostra biológica obtida de um indivíduo e uso de um produto de combinação para detectar um marcador alvo em uma amostra biológica
RU2744836C2 (ru) 2014-05-08 2021-03-16 Новодиакс, Инк. Прямой иммуногистохимический анализ
CN104076153A (zh) * 2014-05-14 2014-10-01 中国科学院海洋研究所 一种基于活性功能分子标记蔗糖酶信号系统及其应用
EP3155426B1 (en) 2014-06-13 2023-07-19 Immudex ApS General detection and isolation of specific cells by binding of labeled molecules
US10579959B2 (en) 2014-09-10 2020-03-03 Cerner Innovation, Inc. Intelligent routing of radio-frequency identification data
CN104312588B (zh) * 2014-09-12 2016-08-03 中国科学院上海微系统与信息技术研究所 一种硒掺杂碳量子点的制备方法
US10746740B2 (en) 2015-01-22 2020-08-18 Konica Minolta, Inc. Biological substance quantitation method, pathological diagnosis support system, and recording medium storing computer readable program
US10839509B2 (en) 2015-07-10 2020-11-17 3Scan Inc. Spatial multiplexing of histological stains
CN113546178A (zh) 2015-12-09 2021-10-26 加利福尼亚大学董事会 治疗眼部疾病或病症的方法
CN105738616A (zh) * 2016-02-02 2016-07-06 基蛋生物科技股份有限公司 双重放大荧光免疫标记探针的制备方法及应用、用其制备荧光免疫层析试剂条的方法
WO2019197365A1 (en) * 2018-04-09 2019-10-17 Expedeon Ltd. Chemical and biological complexes and conjugates with multiple labels and applications thereof
US12258373B2 (en) 2018-12-17 2025-03-25 Immudex Aps Panel comprising Borrelia MHC multimers
WO2020243733A1 (en) * 2019-05-30 2020-12-03 Sakura Finetek Usa, Inc. Detection of antigens in a biological specimen using antibody reagents
CN111830250A (zh) * 2020-08-04 2020-10-27 珠海市丽拓生物科技有限公司 一种信号放大的酶标二抗的制备方法
CN111965341B (zh) * 2020-08-10 2023-04-11 武汉菲恩生物科技有限公司 一种基于葡聚糖的HRP-羊抗鼠IgG标记抗体及其制备方法
JP2023543982A (ja) * 2020-09-30 2023-10-19 アジレント・テクノロジーズ・インク 電場により支援される試料の調製
CN112834736B (zh) * 2020-12-02 2024-09-06 杭州百凌生物科技有限公司 一种检测多种抗原的病理检测试剂盒及其制备方法和应用
CN112694517B (zh) * 2020-12-02 2022-04-05 图凌(杭州)生物医药有限公司 一种人工多肽pl、其抗体及在病理检测中的应用
CN112694521B (zh) * 2020-12-02 2023-01-17 杭州百凌生物科技有限公司 一种人工多肽lh、其抗体及在病理检测中的应用
CN112592385B (zh) * 2020-12-02 2023-02-03 杭州百凌生物科技有限公司 一种人工多肽组合物、其抗体及在病理检测中的应用
CN112694520B (zh) * 2020-12-02 2023-01-17 图凌(杭州)生物医药有限公司 一种人工多肽hm、其抗体及在病理检测中的应用
JP2024509725A (ja) * 2021-02-05 2024-03-05 ベックマン コールター, インコーポレイテッド ポリマー色素-抗体コンジュゲート間の非特異的相互作用を阻止する組成物および方法
CN113391059B (zh) * 2021-06-10 2022-06-03 上海百英生物科技有限公司 一种micropolymer-HRP-纳米抗体复合物及其制备方法
CN114113605B (zh) * 2021-11-04 2022-11-11 贵州美鑫达医疗科技有限公司 用于脑瘤术中快速免疫组化的多聚酶-抗体组合
CN115554463A (zh) * 2022-03-08 2023-01-03 石河子大学 一种具有抗冻、抗菌、光热转换功能的医用凝胶敷料的制备方法
CN114354718A (zh) * 2022-03-18 2022-04-15 南京邮电大学 纳米酶在催化增强电化学发光信号及单细胞表面膜蛋白成像中的应用
CN119470882B (zh) * 2025-01-08 2025-04-11 百盛(广州)生物制品有限公司 一种用于免疫组织化学染色的酶标二抗多聚物
CN120043837A (zh) * 2025-04-23 2025-05-27 广州金域医学检验集团股份有限公司 免疫组化多重染色切片及其制备方法和应用
CN120795341B (zh) * 2025-09-10 2025-11-21 山东新生命医疗科技有限公司 一种超支化聚合物hrp及其制备方法和应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4017597A (en) * 1974-10-30 1977-04-12 Monsanto Company Unitized solid phase immunoassay kit and method
US4711955A (en) * 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
US4609707A (en) * 1983-11-10 1986-09-02 Genetic Systems Corporation Synthesis of polymers containing integral antibodies
JPS62235564A (ja) 1986-04-07 1987-10-15 Toyobo Co Ltd エリスロポエチンの免疫学的測定法
US4959306A (en) 1986-11-28 1990-09-25 Sclavo, Inc. Labeling design for a binding assay reagent
JPH02500329A (ja) 1987-05-21 1990-02-08 クリエイテイブ・バイオマリキユールズ・インコーポレーテツド ターゲット化多機能蛋白質
US5567584A (en) 1988-01-22 1996-10-22 Zymogenetics, Inc. Methods of using biologically active dimerized polypeptide fusions to detect PDGF
DE768377T1 (de) 1988-09-02 1998-01-02 Dyax Corp Herstellung und Auswahl von Rekombinantproteinen mit verschiedenen Bindestellen
ATE102631T1 (de) 1988-11-11 1994-03-15 Medical Res Council Klonierung von immunglobulin sequenzen aus den variabelen domaenen.
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
US5296347A (en) 1991-02-08 1994-03-22 Ciba Corning Diagnostics Corp. Bridge immunoassay
DK130991D0 (da) * 1991-07-04 1991-07-04 Immunodex K S Polymere konjugater
DK0594772T3 (enExample) 1991-07-04 1997-02-24 Immunodex K S
AU1449092A (en) 1992-02-24 1993-09-13 Triton Diagnostics, Inc. Bridge immunoassay
SE504798C2 (sv) 1995-06-16 1997-04-28 Ulf Landegren Immunanalys och testkit med två reagens som kan tvärbindas om de adsorberats till analyten
DE19634730A1 (de) 1996-08-28 1998-03-05 Viva Diagnostika Diagnostische Neue Kombinationspräparationen und ihre Verwendung in der Immundiagnostik und Immuntherapie
US6117631A (en) 1996-10-29 2000-09-12 Polyprobe, Inc. Detection of antigens via oligonucleotide antibody conjugates
CA2336564C (en) * 1998-07-30 2011-06-28 Amdex A/S Method for preparing water-soluble cross-linked conjugates
US6406858B1 (en) * 1998-11-27 2002-06-18 Bayer Corporation System for the reduction of interferences in immunoassays
JP2000214165A (ja) 1999-01-22 2000-08-04 Fuji Photo Film Co Ltd 均一系酵素免疫分析方法
GB0029617D0 (en) * 2000-12-05 2001-01-17 Norchip As Ligand detection method
US6727072B2 (en) * 2001-05-01 2004-04-27 Dako Corporation EGF-r detection kit
JP4193055B2 (ja) * 2001-09-19 2008-12-10 積水メディカル株式会社 発光性高分子化合物、及びそのバイオアッセイにおける利用
US20040081653A1 (en) * 2002-08-16 2004-04-29 Raitano Arthur B. Nucleic acids and corresponding proteins entitled 251P5G2 useful in treatment and detection of cancer

Also Published As

Publication number Publication date
CA2544577C (en) 2013-01-08
EP1697750B1 (en) 2013-03-20
JP2007513334A (ja) 2007-05-24
WO2005054860A1 (en) 2005-06-16
US20050208529A1 (en) 2005-09-22
CA2544577A1 (en) 2005-06-16
US8632994B2 (en) 2014-01-21
AU2004295699A1 (en) 2005-06-16
EP1697750A1 (en) 2006-09-06

Similar Documents

Publication Publication Date Title
JP4949038B2 (ja) 免疫組織化学的検出のための方法および組成物
Buchwalow et al. Immunohistochemistry: basics and methods
JP6770150B2 (ja) 免疫組織化学およびin situハイブリダーゼーションのためのポリマー担体
JP7630676B2 (ja) 抗原をカップリングさせた免疫試薬
JP5721638B2 (ja) コンジュゲート分子
RU2566714C2 (ru) Иммунохимическое определение одиночных мишеней
CN103328979B (zh) 组合的组织学染色
JP4800195B2 (ja) 免疫組織化学、免疫細胞化学および分子細胞遺伝学のための標準
US20240069034A1 (en) Proximity assays using chemical ligation and hapten transfer
CN103597089B (zh) 用于酶介导的信号放大的方法
US20190112356A1 (en) High-affinity immunopolymers
KR20200128689A (ko) Magea4 검출 방법
JP2011157363A (ja) Cyp1b1に特異的な抗体
JP5727931B2 (ja) アッセイ
US11821901B2 (en) Styryl phenols, derivatives and their use in methods of analyte detection
WO2013116537A1 (en) A method to distinguish benign from malignant oncocytic cell tissue
Sridhar Immunohistochemistry of carcinomas using monoclonal antibody, JAA-F11

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20071119

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20071119

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100209

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20100428

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20100511

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100809

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20101202

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20110302

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20110309

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110401

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110921

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20111219

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20120302

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20120307

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20150316

Year of fee payment: 3

R150 Certificate of patent or registration of utility model

Ref document number: 4949038

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313113

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

S533 Written request for registration of change of name

Free format text: JAPANESE INTERMEDIATE CODE: R313533

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

EXPY Cancellation because of completion of term