JP4895476B2 - タキキニン受容体アンタゴニスト - Google Patents

タキキニン受容体アンタゴニスト Download PDF

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JP4895476B2
JP4895476B2 JP2003587787A JP2003587787A JP4895476B2 JP 4895476 B2 JP4895476 B2 JP 4895476B2 JP 2003587787 A JP2003587787 A JP 2003587787A JP 2003587787 A JP2003587787 A JP 2003587787A JP 4895476 B2 JP4895476 B2 JP 4895476B2
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Japan
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phenyl
trifluoromethyl
bis
benzyl
formula
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Japanese (ja)
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JP2005534627A (ja
JP2005534627A5 (https=
Inventor
アルバート・クゾビ・アメガジエ
ケビン・マシュー・ガーディニアー
エリック・ジェイムズ・ヘンバー
ホン・ジャン・エリック
ルイス・ニコラウス・ジュンガイム
マイケル・アラン・ロバートソン
ケネス・アレン・セイビン
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イーライ リリー アンド カンパニー
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
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    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
JP2003587787A 2002-04-26 2003-04-22 タキキニン受容体アンタゴニスト Expired - Fee Related JP4895476B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US37612102P 2002-04-26 2002-04-26
US60/376,121 2002-04-26
US44086503P 2003-01-16 2003-01-16
US60/440,865 2003-01-16
PCT/US2003/010682 WO2003091227A1 (en) 2002-04-26 2003-04-22 Tachykinin receptor antagonists

Publications (3)

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JP2005534627A JP2005534627A (ja) 2005-11-17
JP2005534627A5 JP2005534627A5 (https=) 2006-06-15
JP4895476B2 true JP4895476B2 (ja) 2012-03-14

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JP2003587787A Expired - Fee Related JP4895476B2 (ja) 2002-04-26 2003-04-22 タキキニン受容体アンタゴニスト

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US (1) US7179804B2 (https=)
EP (1) EP1501808B1 (https=)
JP (1) JP4895476B2 (https=)
CN (1) CN1313450C (https=)
AT (1) ATE399770T1 (https=)
BR (1) BR0309486A (https=)
CA (1) CA2484188C (https=)
CY (1) CY1108539T1 (https=)
DE (1) DE60321907D1 (https=)
DK (1) DK1501808T3 (https=)
ES (1) ES2307925T3 (https=)
IL (1) IL164787A0 (https=)
MX (1) MXPA04010625A (https=)
PT (1) PT1501808E (https=)
SI (1) SI1501808T1 (https=)
WO (1) WO2003091227A1 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003230829B8 (en) * 2002-04-26 2008-12-11 Eli Lilly And Company Triazole derivatives as tachykinin receptor antagonists
WO2005000821A1 (en) * 2003-06-12 2005-01-06 Eli Lilly And Company Tachykinin receptor antagonists
WO2005033079A1 (ja) * 2003-09-30 2005-04-14 Eisai Co., Ltd. ヘテロ環化合物を含有する新規な抗真菌剤
US20050241110A1 (en) * 2004-04-09 2005-11-03 Bruce Baker Ergonomic handles, especially for garden tools
US20090227799A1 (en) * 2004-08-09 2009-09-10 Kazutaka Nakamoto Novel Antimalarial Agent Containing Heterocyclic Compound
EP1864980A4 (en) 2005-03-30 2010-08-18 Eisai R&D Man Co Ltd A PYRIDINE DERIVATIVE ANTIPILIC AGENT
TW200716576A (en) * 2005-06-07 2007-05-01 Shionogi & Co Heterocyclic derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
CN101228137B (zh) * 2005-07-25 2010-09-29 弗·哈夫曼-拉罗切有限公司 被取代的三唑衍生物和它们作为神经激肽3受体拮抗剂的用途
TWI385169B (zh) * 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
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JP2005534627A (ja) 2005-11-17
AU2003224868A1 (en) 2003-11-10
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CA2484188A1 (en) 2003-11-06
SI1501808T1 (sl) 2008-10-31
US20050239776A1 (en) 2005-10-27
AU2003224868B2 (en) 2008-11-20
US7179804B2 (en) 2007-02-20
ES2307925T3 (es) 2008-12-01
DK1501808T3 (da) 2008-10-13
IL164787A0 (en) 2005-12-18
BR0309486A (pt) 2005-02-09
CN1313450C (zh) 2007-05-02
CN1649849A (zh) 2005-08-03
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WO2003091227A1 (en) 2003-11-06
ATE399770T1 (de) 2008-07-15

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