JP4874523B2 - 不正使用防止機能付きの経皮的オピオイド送給装置 - Google Patents
不正使用防止機能付きの経皮的オピオイド送給装置 Download PDFInfo
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- JP4874523B2 JP4874523B2 JP2003569151A JP2003569151A JP4874523B2 JP 4874523 B2 JP4874523 B2 JP 4874523B2 JP 2003569151 A JP2003569151 A JP 2003569151A JP 2003569151 A JP2003569151 A JP 2003569151A JP 4874523 B2 JP4874523 B2 JP 4874523B2
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- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- opioid
- delivery device
- transdermal delivery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 150000003839 salts Chemical class 0.000 claims abstract description 282
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- IYNWSQDZXMGGGI-NUEKZKHPSA-N 3-hydroxymorphinan Chemical compound C1CCC[C@H]2[C@H]3CC4=CC=C(O)C=C4[C@]21CCN3 IYNWSQDZXMGGGI-NUEKZKHPSA-N 0.000 claims description 2
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| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| ES2323127T3 (es) * | 2002-08-20 | 2009-07-07 | Euro-Celtique S.A. | Forma posologica transdermica que comprende un agente activo y una forma de sal y una forma de base libre de un antagonista. |
| US8790689B2 (en) * | 2003-04-30 | 2014-07-29 | Purdue Pharma L.P. | Tamper resistant transdermal dosage form |
| BRPI0409945A (pt) * | 2003-04-30 | 2006-04-25 | Purdue Pharma Lp | forma de dosagem resistente à alteração |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| US20070191815A1 (en) | 2004-09-13 | 2007-08-16 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery |
| US7867511B2 (en) * | 2004-01-23 | 2011-01-11 | Travanti Pharma Inc. | Abuse potential reduction in abusable substance dosage form |
| US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
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| US9056061B2 (en) | 2005-09-23 | 2015-06-16 | Alza Corporation | Transdermal nicotine salt delivery system |
| EP2308480B1 (en) | 2005-09-23 | 2014-08-13 | ALZA Corporation | High Enhancer-Loading Polyacrylate Formulation for Transdermal Applications |
| US9522188B2 (en) | 2005-12-13 | 2016-12-20 | Biodelivery Sciences International, Inc. | Abuse resistant transmucosal drug delivery device |
| GB0606124D0 (en) * | 2006-03-28 | 2006-05-03 | Reckitt Benckiser Healthcare | Buprenorphine derivatives and uses thereof |
| ES2577390T3 (es) | 2006-07-21 | 2016-07-14 | Biodelivery Sciences International, Inc. | Dispositivos de administración transmucosa con mayor captación |
| DE202006018609U1 (de) * | 2006-08-29 | 2007-05-16 | Euro-Celtique S.A. | Verwendung von Opioidformulierungen in nadellosen Vorrichtungen zur Medikamentenverabreichung |
| ES2549115T3 (es) * | 2006-09-22 | 2015-10-23 | Zynerba Pharmaceuticals, Inc. | Profármacos de buprenorfina administrables por vía transdérmica y composiciones resistentes al consumo excesivo de los mismos |
| TWI454288B (zh) | 2008-01-25 | 2014-10-01 | Gruenenthal Chemie | 藥物劑型 |
| US9700552B2 (en) | 2008-02-28 | 2017-07-11 | Syntropharma Limited | Pharmaceutical compositions for treatment of addiction |
| CA2718943A1 (en) * | 2008-03-26 | 2009-10-01 | Alltranz Inc. | Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists |
| EP2291380B1 (en) * | 2008-04-24 | 2011-09-07 | Janssen Pharmaceutica N.V. | Nalmefene prodrugs |
| TWI630208B (zh) | 2008-12-08 | 2018-07-21 | 歐陸斯迪公司 | 二氫羥戊甲嗎啡 |
| US10363251B2 (en) | 2009-07-16 | 2019-07-30 | Mallinckrodt Llc | (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof |
| BR112012001466A2 (pt) | 2009-07-22 | 2020-08-11 | Grünenthal GmbH | forma de dosagem resistente à falsificação para opioides sensíveis à oxidação, seu processo de fabricação, e embalagem |
| ES2534908T3 (es) | 2009-07-22 | 2015-04-30 | Grünenthal GmbH | Forma de dosificación de liberación controlada extruida por fusión en caliente |
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- 2003-02-19 SI SI200331243T patent/SI1476141T1/sl unknown
- 2003-02-19 DE DE60320530T patent/DE60320530T2/de not_active Expired - Lifetime
- 2003-02-19 AT AT03742830T patent/ATE392892T1/de active
- 2003-02-19 DK DK03742830T patent/DK1476141T3/da active
- 2003-02-19 ES ES03742830T patent/ES2305480T3/es not_active Expired - Lifetime
- 2003-02-19 JP JP2003569151A patent/JP4874523B2/ja not_active Expired - Fee Related
- 2003-02-19 WO PCT/US2003/004999 patent/WO2003070191A2/en not_active Ceased
- 2003-02-19 AU AU2003216321A patent/AU2003216321A1/en not_active Abandoned
- 2003-02-19 PT PT03742830T patent/PT1476141E/pt unknown
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2008
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2010
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Also Published As
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| ATE392892T1 (de) | 2008-05-15 |
| SI1476141T1 (sl) | 2008-08-31 |
| DK1476141T3 (da) | 2008-08-18 |
| JP5453151B2 (ja) | 2014-03-26 |
| JP2013237692A (ja) | 2013-11-28 |
| CY1108201T1 (el) | 2014-02-12 |
| JP2006502967A (ja) | 2006-01-26 |
| WO2003070191A3 (en) | 2004-09-10 |
| ES2305480T3 (es) | 2008-11-01 |
| JP2010189403A (ja) | 2010-09-02 |
| EP1476141B1 (en) | 2008-04-23 |
| EP1476141A2 (en) | 2004-11-17 |
| AU2003216321A8 (en) | 2003-09-09 |
| WO2003070191A8 (en) | 2004-06-10 |
| DE60320530T2 (de) | 2009-06-10 |
| AU2003216321A1 (en) | 2003-09-09 |
| US20040033253A1 (en) | 2004-02-19 |
| WO2003070191A2 (en) | 2003-08-28 |
| PT1476141E (pt) | 2008-07-03 |
| DE60320530D1 (de) | 2008-06-05 |
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