JP4824545B2 - 質量分析方法、及び質量分析計 - Google Patents

質量分析方法、及び質量分析計 Download PDF

Info

Publication number
JP4824545B2
JP4824545B2 JP2006508377A JP2006508377A JP4824545B2 JP 4824545 B2 JP4824545 B2 JP 4824545B2 JP 2006508377 A JP2006508377 A JP 2006508377A JP 2006508377 A JP2006508377 A JP 2006508377A JP 4824545 B2 JP4824545 B2 JP 4824545B2
Authority
JP
Japan
Prior art keywords
ions
mass
ion
trap
charge ratio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2006508377A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006526265A (ja
JP2006526265A5 (enExample
Inventor
アレクサンダー マカロフ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thermo Finnigan LLC
Original Assignee
Thermo Finnigan LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thermo Finnigan LLC filed Critical Thermo Finnigan LLC
Publication of JP2006526265A publication Critical patent/JP2006526265A/ja
Publication of JP2006526265A5 publication Critical patent/JP2006526265A5/ja
Application granted granted Critical
Publication of JP4824545B2 publication Critical patent/JP4824545B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/4245—Electrostatic ion traps
    • H01J49/425—Electrostatic ion traps with a logarithmic radial electric potential, e.g. orbitraps
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
JP2006508377A 2003-05-30 2004-05-28 質量分析方法、及び質量分析計 Expired - Fee Related JP4824545B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0312447.6 2003-05-30
GB0312447A GB2402260B (en) 2003-05-30 2003-05-30 All mass MS/MS method and apparatus
PCT/GB2004/002289 WO2004107388A2 (en) 2003-05-30 2004-05-28 All-mass ms/ms method and apparatus

Publications (3)

Publication Number Publication Date
JP2006526265A JP2006526265A (ja) 2006-11-16
JP2006526265A5 JP2006526265A5 (enExample) 2007-07-26
JP4824545B2 true JP4824545B2 (ja) 2011-11-30

Family

ID=9959050

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006508377A Expired - Fee Related JP4824545B2 (ja) 2003-05-30 2004-05-28 質量分析方法、及び質量分析計

Country Status (9)

Country Link
US (2) US7399962B2 (enExample)
EP (1) EP1629519B1 (enExample)
JP (1) JP4824545B2 (enExample)
CN (1) CN100555554C (enExample)
AT (1) ATE366992T1 (enExample)
CA (1) CA2527081C (enExample)
DE (1) DE602004007514T2 (enExample)
GB (1) GB2402260B (enExample)
WO (1) WO2004107388A2 (enExample)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020115056A1 (en) 2000-12-26 2002-08-22 Goodlett David R. Rapid and quantitative proteome analysis and related methods
GB0305796D0 (en) 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
GB2402260B (en) * 2003-05-30 2006-05-24 Thermo Finnigan Llc All mass MS/MS method and apparatus
GB0312940D0 (en) * 2003-06-05 2003-07-09 Shimadzu Res Lab Europe Ltd A method for obtaining high accuracy mass spectra using an ion trap mass analyser and a method for determining and/or reducing chemical shift in mass analysis
WO2006103448A2 (en) * 2005-03-29 2006-10-05 Thermo Finnigan Llc Improvements relating to a mass spectrometer
GB2427067B (en) * 2005-03-29 2010-02-24 Thermo Finnigan Llc Improvements relating to ion trapping
GB0511083D0 (en) * 2005-05-31 2005-07-06 Thermo Finnigan Llc Multiple ion injection in mass spectrometry
GB2434484B (en) 2005-06-03 2010-11-03 Thermo Finnigan Llc Improvements in an electrostatic trap
GB0513047D0 (en) * 2005-06-27 2005-08-03 Thermo Finnigan Llc Electronic ion trap
JP4830450B2 (ja) * 2005-11-02 2011-12-07 株式会社島津製作所 質量分析装置
GB2432712B (en) * 2005-11-23 2007-12-27 Micromass Ltd Mass spectrometer
GB0523806D0 (en) * 2005-11-23 2006-01-04 Micromass Ltd Mass spectrometer
GB0523811D0 (en) * 2005-11-23 2006-01-04 Micromass Ltd Mass stectrometer
US20080173807A1 (en) * 2006-04-11 2008-07-24 Oh-Kyu Yoon Fragmentation modulation mass spectrometry
JP4802032B2 (ja) * 2006-04-14 2011-10-26 日本電子株式会社 タンデム型質量分析装置
DE102007024858B4 (de) * 2007-04-12 2011-02-10 Bruker Daltonik Gmbh Massenspektrometer mit einer elektrostatischen Ionenfalle
DE102008024297B4 (de) * 2008-05-20 2011-03-31 Bruker Daltonik Gmbh Fragmentierung von Ionen in Kingdon-Ionenfallen
GB0809950D0 (en) 2008-05-30 2008-07-09 Thermo Fisher Scient Bremen Mass spectrometer
CN102077086B (zh) * 2008-07-03 2013-06-05 株式会社岛津制作所 质量分析装置
CN102413907B (zh) * 2009-04-13 2015-06-17 萨莫芬尼根有限责任公司 质谱仪中混合的离子布居的获取与分析
DE102009020886B4 (de) * 2009-05-12 2012-08-30 Bruker Daltonik Gmbh Einspeichern von Ionen in Kíngdon-Ionenfallen
GB2480660B (en) * 2010-05-27 2012-07-11 Thermo Fisher Scient Bremen Mass spectrometry detector system and method of detection
US9922812B2 (en) * 2010-11-26 2018-03-20 Thermo Fisher Scientific (Bremen) Gmbh Method of mass separating ions and mass separator
GB2496994B (en) * 2010-11-26 2015-05-20 Thermo Fisher Scient Bremen Method of mass separating ions and mass separator
GB2544920B (en) 2011-05-12 2018-02-07 Thermo Fisher Scient (Bremen) Gmbh Electrostatic ion trapping with shielding conductor
GB2495068B (en) 2011-05-12 2017-05-10 Thermo Fisher Scient (Bremen) Gmbh Mass analyser
GB201118279D0 (en) * 2011-10-21 2011-12-07 Shimadzu Corp Mass analyser, mass spectrometer and associated methods
DE102012200211A1 (de) * 2012-01-09 2013-07-11 Carl Zeiss Nts Gmbh Vorrichtung und Verfahren zur Oberflächenbearbeitung eines Substrates
CN103367094B (zh) * 2012-03-31 2016-12-14 株式会社岛津制作所 离子阱分析器以及离子阱质谱分析方法
US8796619B1 (en) * 2013-06-11 2014-08-05 Science And Engineering Services, Llc Electrostatic orbital trap mass spectrometer
CN104538278B (zh) * 2014-12-16 2017-01-04 中国科学院长春光学精密机械与物理研究所 一种离子迁移发生装置及其控制方法
CN110718442B (zh) 2015-01-23 2022-08-16 加州理工学院 整合的混合nems质谱测定法
DE102015208188B4 (de) * 2015-05-04 2025-05-22 Leybold Gmbh Verfahren zur massenspektrometrischen Untersuchung eines Gases
GB2549248B (en) 2016-01-12 2020-07-22 Thermo Fisher Scient Bremen Gmbh IRMS sample introduction system and method
EP3193352A1 (en) * 2016-01-14 2017-07-19 Thermo Finnigan LLC Methods for mass spectrometric based characterization of biological molecules
CN107026068A (zh) * 2016-01-29 2017-08-08 北京普析通用仪器有限责任公司 电感耦合等离子体质谱仪及碰撞反应池
US10192730B2 (en) 2016-08-30 2019-01-29 Thermo Finnigan Llc Methods for operating electrostatic trap mass analyzers
GB2559395B (en) 2017-02-03 2020-07-01 Thermo Fisher Scient Bremen Gmbh High resolution MS1 based quantification
EP3958290B1 (en) 2017-06-02 2024-09-25 Thermo Fisher Scientific (Bremen) GmbH Hybrid mass spectrometer
KR102742962B1 (ko) * 2018-11-20 2024-12-16 더 트러스티즈 오브 인디애나 유니버시티 단일 입자 질량 분석을 위한 오비트랩
CN113748487B (zh) * 2019-04-25 2024-09-03 萨默费尼根有限公司 利用谐波振荡和共振离子选择性时间概览（stori）图的电荷检测质谱法
GB2584125B (en) * 2019-05-22 2021-11-03 Thermo Fisher Scient Bremen Gmbh Dynamic control of accumulation time for chromatography mass spectrometry
CN110376272B (zh) * 2019-06-12 2022-02-08 中国科学院微电子研究所 气体分压的在线测量装置及其在线测量方法
CN114388339B (zh) * 2021-11-30 2023-08-29 宁波大学 一种静电离子阱
GB2618673B (en) 2022-05-09 2024-11-06 Thermo Fisher Scient Bremen Gmbh Charge detection for ion accumulation control
CN116206944A (zh) * 2023-04-21 2023-06-02 暨南大学 一种静电场轨道阱、畸变场调节装置以及调节方法
WO2024245675A1 (en) 2023-05-26 2024-12-05 Thermo Fisher Scientific (Bremen) Gmbh Method of operating a mass spectrometer including an ion trap

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11502665A (ja) * 1995-03-31 1999-03-02 エイチデー、テクノロジーズ、リミテッド 質量分析計
JP2005500646A (ja) * 2001-03-23 2005-01-06 サーモ フィニガン リミテッド ライアビリティ カンパニー 質量分析の方法及び装置

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2363364A1 (fr) * 1976-09-07 1978-03-31 Thomson Csf Procede de separation isotopique et installation pour sa mise en oeuvre
FR2376511A1 (fr) * 1976-12-31 1978-07-28 Cameca Spectrometre de masse a balayage ultra-rapide
JPH01213950A (ja) * 1988-02-23 1989-08-28 Jeol Ltd 質量分析装置及びそれを用いたｍｓ／ｍｓ装置
JP2523781B2 (ja) * 1988-04-28 1996-08-14 日本電子株式会社 飛行時間型／偏向二重収束型切換質量分析装置
US4978852A (en) * 1988-09-08 1990-12-18 Cornell Research Foundation, Inc. Hadamard transform measurement of MSN Fourier-transform mass spectra
DE19501835C2 (de) * 1995-01-21 1998-07-02 Bruker Franzen Analytik Gmbh Verfahren zur Anregung der Schwingungen von Ionen in Ionenfallen mit Frequenzgemischen
US5734162A (en) * 1996-04-30 1998-03-31 Hewlett Packard Company Method and apparatus for selectively trapping ions into a quadrupole trap
US5905258A (en) * 1997-06-02 1999-05-18 Advanced Research & Techology Institute Hybrid ion mobility and mass spectrometer
GB0107380D0 (en) 2001-03-23 2001-05-16 Thermo Masslab Ltd Mass spectrometry method and apparatus
JP3653504B2 (ja) * 2002-02-12 2005-05-25 株式会社日立ハイテクノロジーズ イオントラップ型質量分析装置
US7049580B2 (en) * 2002-04-05 2006-05-23 Mds Inc. Fragmentation of ions by resonant excitation in a high order multipole field, low pressure ion trap
US6888130B1 (en) * 2002-05-30 2005-05-03 Marc Gonin Electrostatic ion trap mass spectrometers
GB2402260B (en) * 2003-05-30 2006-05-24 Thermo Finnigan Llc All mass MS/MS method and apparatus
JP4223937B2 (ja) * 2003-12-16 2009-02-12 株式会社日立ハイテクノロジーズ 質量分析装置
US6956217B2 (en) * 2004-02-10 2005-10-18 Archimedes Operating, Llc Mass separator with controlled input
JP4275545B2 (ja) * 2004-02-17 2009-06-10 株式会社日立ハイテクノロジーズ 質量分析装置
EP1749307A4 (en) * 2004-05-24 2010-09-22 Mds Inc Dba Mds Sciex SYSTEM AND METHOD FOR MOUNTING IONS
US7439520B2 (en) * 2005-01-24 2008-10-21 Applied Biosystems Inc. Ion optics systems
US7351960B2 (en) * 2005-05-16 2008-04-01 Thermo Finnigan Llc Enhanced ion desolvation for an ion mobility spectrometry device
GB2434484B (en) * 2005-06-03 2010-11-03 Thermo Finnigan Llc Improvements in an electrostatic trap

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11502665A (ja) * 1995-03-31 1999-03-02 エイチデー、テクノロジーズ、リミテッド 質量分析計
JP2005500646A (ja) * 2001-03-23 2005-01-06 サーモ フィニガン リミテッド ライアビリティ カンパニー 質量分析の方法及び装置

Also Published As

Publication number Publication date
WO2004107388A2 (en) 2004-12-09
GB2402260A (en) 2004-12-01
DE602004007514D1 (de) 2007-08-23
CN100555554C (zh) 2009-10-28
EP1629519B1 (en) 2007-07-11
EP1629519A2 (en) 2006-03-01
DE602004007514T2 (de) 2008-03-06
JP2006526265A (ja) 2006-11-16
US20080258053A1 (en) 2008-10-23
GB0312447D0 (en) 2003-07-09
US7728290B2 (en) 2010-06-01
US7399962B2 (en) 2008-07-15
US20070023629A1 (en) 2007-02-01
ATE366992T1 (de) 2007-08-15
CN1799119A (zh) 2006-07-05
WO2004107388A3 (en) 2005-04-07
CA2527081C (en) 2009-12-22
CA2527081A1 (en) 2004-12-09
GB2402260B (en) 2006-05-24

Similar Documents

Publication Publication Date Title
JP4824545B2 (ja) 質量分析方法、及び質量分析計
JP7092798B2 (ja) 多重反射飛行時間型質量分析器および多重反射飛行時間型質量分析方法
US10593533B2 (en) Imaging mass spectrometer
CN1833300B (zh) 在离子总体中获取多个母离子的串联质谱分析数据
CN103650099B (zh) 串联质谱法的靶向分析
CN102884608B (zh) 离子阱质谱仪
US6852972B2 (en) Mass spectrometer
CN109075012B (zh) 二维msms
US20110155901A1 (en) Merged Ion Beam Tandem TOF-TOF Mass Spectrometer
CA2696513A1 (en) Tandem ion trapping arrangement
US12057303B2 (en) Optimised targeted analysis
US20070221862A1 (en) Coupled Electrostatic Ion and Electron Traps for Electron Capture Dissociation - Tandem Mass Spectrometry
CN107690691B (zh) 陷阱填充时间动态范围增强
EP3069376B1 (en) Method of isolating ions
US11031232B1 (en) Injection of ions into an ion storage device
JP2016514343A (ja) 自動放出イオントラップを用いた質量分析計における気相反応物の改善された反応監視を可能にする装置
WO2003103007A1 (en) Mass spectrometer
Lemière Mass analysers for LC-MS

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070524

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070524

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20100127

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100216

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100517

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100608

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100827

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20110816

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20110908

R150 Certificate of patent or registration of utility model

Ref document number: 4824545

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20140916

Year of fee payment: 3

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

LAPS Cancellation because of no payment of annual fees