DE602004007514D1 - Verfahren und vorrichtung zur tandemmassenspektroskopie zum erstellen eines vollständigen spektrums für alle massen - Google Patents
Verfahren und vorrichtung zur tandemmassenspektroskopie zum erstellen eines vollständigen spektrums für alle massenInfo
- Publication number
- DE602004007514D1 DE602004007514D1 DE602004007514T DE602004007514T DE602004007514D1 DE 602004007514 D1 DE602004007514 D1 DE 602004007514D1 DE 602004007514 T DE602004007514 T DE 602004007514T DE 602004007514 T DE602004007514 T DE 602004007514T DE 602004007514 D1 DE602004007514 D1 DE 602004007514D1
- Authority
- DE
- Germany
- Prior art keywords
- ions
- trap
- mass
- charge ratio
- tandemass
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000004611 spectroscopical analysis Methods 0.000 title 1
- 238000001228 spectrum Methods 0.000 title 1
- 150000002500 ions Chemical class 0.000 abstract 8
- 239000012634 fragment Substances 0.000 abstract 3
- 239000002243 precursor Substances 0.000 abstract 3
- 230000001419 dependent effect Effects 0.000 abstract 2
- 230000005684 electric field Effects 0.000 abstract 2
- 238000010494 dissociation reaction Methods 0.000 abstract 1
- 230000005593 dissociations Effects 0.000 abstract 1
- 238000005040 ion trap Methods 0.000 abstract 1
- 238000001819 mass spectrum Methods 0.000 abstract 1
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
- H01J49/4205—Device types
- H01J49/4245—Electrostatic ion traps
- H01J49/425—Electrostatic ion traps with a logarithmic radial electric potential, e.g. orbitraps
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Electron Tubes For Measurement (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0312447 | 2003-05-30 | ||
GB0312447A GB2402260B (en) | 2003-05-30 | 2003-05-30 | All mass MS/MS method and apparatus |
PCT/GB2004/002289 WO2004107388A2 (en) | 2003-05-30 | 2004-05-28 | All-mass ms/ms method and apparatus |
Publications (2)
Publication Number | Publication Date |
---|---|
DE602004007514D1 true DE602004007514D1 (de) | 2007-08-23 |
DE602004007514T2 DE602004007514T2 (de) | 2008-03-06 |
Family
ID=9959050
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004007514T Expired - Lifetime DE602004007514T2 (de) | 2003-05-30 | 2004-05-28 | Verfahren und vorrichtung zur tandemmassenspektroskopie zum erstellen eines vollständigen spektrums für alle massen |
Country Status (9)
Country | Link |
---|---|
US (2) | US7399962B2 (de) |
EP (1) | EP1629519B1 (de) |
JP (1) | JP4824545B2 (de) |
CN (1) | CN100555554C (de) |
AT (1) | ATE366992T1 (de) |
CA (1) | CA2527081C (de) |
DE (1) | DE602004007514T2 (de) |
GB (1) | GB2402260B (de) |
WO (1) | WO2004107388A2 (de) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
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US20020115056A1 (en) | 2000-12-26 | 2002-08-22 | Goodlett David R. | Rapid and quantitative proteome analysis and related methods |
GB0305796D0 (en) | 2002-07-24 | 2003-04-16 | Micromass Ltd | Method of mass spectrometry and a mass spectrometer |
GB2402260B (en) * | 2003-05-30 | 2006-05-24 | Thermo Finnigan Llc | All mass MS/MS method and apparatus |
GB0312940D0 (en) * | 2003-06-05 | 2003-07-09 | Shimadzu Res Lab Europe Ltd | A method for obtaining high accuracy mass spectra using an ion trap mass analyser and a method for determining and/or reducing chemical shift in mass analysis |
CA2601707C (en) * | 2005-03-29 | 2012-05-15 | Thermo Finnigan Llc | Improvements relating to a mass spectrometer |
GB2427067B (en) * | 2005-03-29 | 2010-02-24 | Thermo Finnigan Llc | Improvements relating to ion trapping |
GB0511083D0 (en) * | 2005-05-31 | 2005-07-06 | Thermo Finnigan Llc | Multiple ion injection in mass spectrometry |
GB2434484B (en) * | 2005-06-03 | 2010-11-03 | Thermo Finnigan Llc | Improvements in an electrostatic trap |
GB0513047D0 (en) | 2005-06-27 | 2005-08-03 | Thermo Finnigan Llc | Electronic ion trap |
JP4830450B2 (ja) * | 2005-11-02 | 2011-12-07 | 株式会社島津製作所 | 質量分析装置 |
GB2432712B (en) * | 2005-11-23 | 2007-12-27 | Micromass Ltd | Mass spectrometer |
GB0523806D0 (en) * | 2005-11-23 | 2006-01-04 | Micromass Ltd | Mass spectrometer |
GB0523811D0 (en) * | 2005-11-23 | 2006-01-04 | Micromass Ltd | Mass stectrometer |
US20080173807A1 (en) * | 2006-04-11 | 2008-07-24 | Oh-Kyu Yoon | Fragmentation modulation mass spectrometry |
JP4802032B2 (ja) * | 2006-04-14 | 2011-10-26 | 日本電子株式会社 | タンデム型質量分析装置 |
DE102007024858B4 (de) * | 2007-04-12 | 2011-02-10 | Bruker Daltonik Gmbh | Massenspektrometer mit einer elektrostatischen Ionenfalle |
DE102008024297B4 (de) * | 2008-05-20 | 2011-03-31 | Bruker Daltonik Gmbh | Fragmentierung von Ionen in Kingdon-Ionenfallen |
GB0809950D0 (en) | 2008-05-30 | 2008-07-09 | Thermo Fisher Scient Bremen | Mass spectrometer |
JP5206790B2 (ja) * | 2008-07-03 | 2013-06-12 | 株式会社島津製作所 | 質量分析装置 |
EP2419198B1 (de) * | 2009-04-13 | 2020-01-08 | Thermo Finnigan LLC | Erfassung und analyse von gemischten ionenpopulationen in einem massenspektrometer |
DE102009020886B4 (de) * | 2009-05-12 | 2012-08-30 | Bruker Daltonik Gmbh | Einspeichern von Ionen in Kíngdon-Ionenfallen |
GB2480660B (en) * | 2010-05-27 | 2012-07-11 | Thermo Fisher Scient Bremen | Mass spectrometry detector system and method of detection |
GB2485826B (en) * | 2010-11-26 | 2015-06-17 | Thermo Fisher Scient Bremen | Method of mass separating ions and mass separator |
US9922812B2 (en) * | 2010-11-26 | 2018-03-20 | Thermo Fisher Scientific (Bremen) Gmbh | Method of mass separating ions and mass separator |
GB2495068B (en) * | 2011-05-12 | 2017-05-10 | Thermo Fisher Scient (Bremen) Gmbh | Mass analyser |
GB2502243B (en) | 2011-05-12 | 2018-01-03 | Thermo Fisher Scient (Bremen) Gmbh | Ion detection |
GB201118279D0 (en) * | 2011-10-21 | 2011-12-07 | Shimadzu Corp | Mass analyser, mass spectrometer and associated methods |
DE102012200211A1 (de) * | 2012-01-09 | 2013-07-11 | Carl Zeiss Nts Gmbh | Vorrichtung und Verfahren zur Oberflächenbearbeitung eines Substrates |
CN103367094B (zh) * | 2012-03-31 | 2016-12-14 | 株式会社岛津制作所 | 离子阱分析器以及离子阱质谱分析方法 |
US8796619B1 (en) * | 2013-06-11 | 2014-08-05 | Science And Engineering Services, Llc | Electrostatic orbital trap mass spectrometer |
CN104538278B (zh) * | 2014-12-16 | 2017-01-04 | 中国科学院长春光学精密机械与物理研究所 | 一种离子迁移发生装置及其控制方法 |
CN110718442B (zh) | 2015-01-23 | 2022-08-16 | 加州理工学院 | 整合的混合nems质谱测定法 |
DE102015208188A1 (de) * | 2015-05-04 | 2016-11-24 | Carl Zeiss Smt Gmbh | Verfahren zur massenspektrometrischen Untersuchung eines Gases und Massenspektrometer |
GB2549248B (en) | 2016-01-12 | 2020-07-22 | Thermo Fisher Scient Bremen Gmbh | IRMS sample introduction system and method |
EP3193352A1 (de) * | 2016-01-14 | 2017-07-19 | Thermo Finnigan LLC | Verfahren zur massenspektrometriebasierten charakterisierung von biologischen molekülen |
CN107026068A (zh) * | 2016-01-29 | 2017-08-08 | 北京普析通用仪器有限责任公司 | 电感耦合等离子体质谱仪及碰撞反应池 |
US10192730B2 (en) | 2016-08-30 | 2019-01-29 | Thermo Finnigan Llc | Methods for operating electrostatic trap mass analyzers |
GB2559395B (en) | 2017-02-03 | 2020-07-01 | Thermo Fisher Scient Bremen Gmbh | High resolution MS1 based quantification |
EP3410463B1 (de) | 2017-06-02 | 2021-07-28 | Thermo Fisher Scientific (Bremen) GmbH | Hybrides massenspektrometer |
EP3884510A1 (de) * | 2018-11-20 | 2021-09-29 | The Trustees of Indiana University | Orbitrap für einzelteilchen-massenspektrometrie |
US12051579B2 (en) * | 2019-04-25 | 2024-07-30 | Thermo Finnigan Llc | Charge detection mass spectrometry utilizing harmonic oscillation and selective temporal overview of resonant ion (STORI) plots |
GB2584125B (en) * | 2019-05-22 | 2021-11-03 | Thermo Fisher Scient Bremen Gmbh | Dynamic control of accumulation time for chromatography mass spectrometry |
CN110376272B (zh) * | 2019-06-12 | 2022-02-08 | 中国科学院微电子研究所 | 气体分压的在线测量装置及其在线测量方法 |
CN114388339B (zh) * | 2021-11-30 | 2023-08-29 | 宁波大学 | 一种静电离子阱 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2363364A1 (fr) * | 1976-09-07 | 1978-03-31 | Thomson Csf | Procede de separation isotopique et installation pour sa mise en oeuvre |
FR2376511A1 (fr) * | 1976-12-31 | 1978-07-28 | Cameca | Spectrometre de masse a balayage ultra-rapide |
JPH01213950A (ja) * | 1988-02-23 | 1989-08-28 | Jeol Ltd | 質量分析装置及びそれを用いたms/ms装置 |
JP2523781B2 (ja) * | 1988-04-28 | 1996-08-14 | 日本電子株式会社 | 飛行時間型/偏向二重収束型切換質量分析装置 |
US4978852A (en) * | 1988-09-08 | 1990-12-18 | Cornell Research Foundation, Inc. | Hadamard transform measurement of MSN Fourier-transform mass spectra |
DE19501835C2 (de) * | 1995-01-21 | 1998-07-02 | Bruker Franzen Analytik Gmbh | Verfahren zur Anregung der Schwingungen von Ionen in Ionenfallen mit Frequenzgemischen |
GB9506695D0 (en) * | 1995-03-31 | 1995-05-24 | Hd Technologies Limited | Improvements in or relating to a mass spectrometer |
US5734162A (en) * | 1996-04-30 | 1998-03-31 | Hewlett Packard Company | Method and apparatus for selectively trapping ions into a quadrupole trap |
GB0107380D0 (en) | 2001-03-23 | 2001-05-16 | Thermo Masslab Ltd | Mass spectrometry method and apparatus |
GB2404784B (en) * | 2001-03-23 | 2005-06-22 | Thermo Finnigan Llc | Mass spectrometry method and apparatus |
JP3653504B2 (ja) * | 2002-02-12 | 2005-05-25 | 株式会社日立ハイテクノロジーズ | イオントラップ型質量分析装置 |
US7049580B2 (en) * | 2002-04-05 | 2006-05-23 | Mds Inc. | Fragmentation of ions by resonant excitation in a high order multipole field, low pressure ion trap |
US6888130B1 (en) * | 2002-05-30 | 2005-05-03 | Marc Gonin | Electrostatic ion trap mass spectrometers |
GB2402260B (en) * | 2003-05-30 | 2006-05-24 | Thermo Finnigan Llc | All mass MS/MS method and apparatus |
JP4223937B2 (ja) * | 2003-12-16 | 2009-02-12 | 株式会社日立ハイテクノロジーズ | 質量分析装置 |
US6956217B2 (en) * | 2004-02-10 | 2005-10-18 | Archimedes Operating, Llc | Mass separator with controlled input |
JP4275545B2 (ja) * | 2004-02-17 | 2009-06-10 | 株式会社日立ハイテクノロジーズ | 質量分析装置 |
JP2008500684A (ja) * | 2004-05-24 | 2008-01-10 | エムディーエス インコーポレイテッド ドゥーイング ビジネス アズ エムディーエス サイエックス | トラップイオン用の装置および方法 |
US7439520B2 (en) * | 2005-01-24 | 2008-10-21 | Applied Biosystems Inc. | Ion optics systems |
US7351960B2 (en) * | 2005-05-16 | 2008-04-01 | Thermo Finnigan Llc | Enhanced ion desolvation for an ion mobility spectrometry device |
GB2434484B (en) * | 2005-06-03 | 2010-11-03 | Thermo Finnigan Llc | Improvements in an electrostatic trap |
-
2003
- 2003-05-30 GB GB0312447A patent/GB2402260B/en not_active Expired - Fee Related
-
2004
- 2004-05-28 WO PCT/GB2004/002289 patent/WO2004107388A2/en active IP Right Grant
- 2004-05-28 JP JP2006508377A patent/JP4824545B2/ja not_active Expired - Fee Related
- 2004-05-28 EP EP04735258A patent/EP1629519B1/de not_active Expired - Lifetime
- 2004-05-28 CA CA002527081A patent/CA2527081C/en not_active Expired - Fee Related
- 2004-05-28 CN CNB2004800148183A patent/CN100555554C/zh not_active Expired - Fee Related
- 2004-05-28 AT AT04735258T patent/ATE366992T1/de not_active IP Right Cessation
- 2004-05-28 US US10/558,184 patent/US7399962B2/en active Active
- 2004-05-28 DE DE602004007514T patent/DE602004007514T2/de not_active Expired - Lifetime
-
2008
- 2008-07-01 US US12/166,296 patent/US7728290B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP4824545B2 (ja) | 2011-11-30 |
EP1629519B1 (de) | 2007-07-11 |
US20070023629A1 (en) | 2007-02-01 |
GB0312447D0 (en) | 2003-07-09 |
CN1799119A (zh) | 2006-07-05 |
CA2527081C (en) | 2009-12-22 |
GB2402260A (en) | 2004-12-01 |
US7728290B2 (en) | 2010-06-01 |
EP1629519A2 (de) | 2006-03-01 |
CN100555554C (zh) | 2009-10-28 |
WO2004107388A2 (en) | 2004-12-09 |
DE602004007514T2 (de) | 2008-03-06 |
US7399962B2 (en) | 2008-07-15 |
WO2004107388A3 (en) | 2005-04-07 |
US20080258053A1 (en) | 2008-10-23 |
CA2527081A1 (en) | 2004-12-09 |
GB2402260B (en) | 2006-05-24 |
JP2006526265A (ja) | 2006-11-16 |
ATE366992T1 (de) | 2007-08-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |