JP4763690B2 - 生化学的分析のために液滴を扱う装置、前記装置を製造する方法及びマイクロ流体分析 - Google Patents

生化学的分析のために液滴を扱う装置、前記装置を製造する方法及びマイクロ流体分析 Download PDF

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JP4763690B2
JP4763690B2 JP2007514033A JP2007514033A JP4763690B2 JP 4763690 B2 JP4763690 B2 JP 4763690B2 JP 2007514033 A JP2007514033 A JP 2007514033A JP 2007514033 A JP2007514033 A JP 2007514033A JP 4763690 B2 JP4763690 B2 JP 4763690B2
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wetting
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electrode
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JP2008502882A (ja
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ジャン−クリストフ・フーリエ
フランソワ・カロン
ピエール・タブリエ
クリスティアン・ドゥロン
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ユニベールシテ・デ・スジャンス・エ・テクノロジー・ドゥ・リル
サントル・ナショナル・ドゥ・ラ・レシェルシュ・サイエンティフィーク−セ・エン・エール・エス−
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
    • F04B19/006—Micropumps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/165—Specific details about hydrophobic, oleophobic surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0427—Electrowetting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/088—Passive control of flow resistance by specific surface properties
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F05—INDEXING SCHEMES RELATING TO ENGINES OR PUMPS IN VARIOUS SUBCLASSES OF CLASSES F01-F04
    • F05C—INDEXING SCHEME RELATING TO MATERIALS, MATERIAL PROPERTIES OR MATERIAL CHARACTERISTICS FOR MACHINES, ENGINES OR PUMPS OTHER THAN NON-POSITIVE-DISPLACEMENT MACHINES OR ENGINES
    • F05C2225/00—Synthetic polymers, e.g. plastics; Rubber
    • F05C2225/04—PTFE [PolyTetraFluorEthylene]

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Micromachines (AREA)
JP2007514033A 2004-06-04 2005-06-06 生化学的分析のために液滴を扱う装置、前記装置を製造する方法及びマイクロ流体分析 Expired - Fee Related JP4763690B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0406080A FR2871150B1 (fr) 2004-06-04 2004-06-04 Dispositif de manipulation de gouttes destine a l'analyse biochimique, procede de fabrication du dispositif, et systeme d'analyse microfluidique
FR0406080 2004-06-04
PCT/FR2005/001385 WO2006003293A2 (fr) 2004-06-04 2005-06-06 Dispositif de manipulation de gouttes destine a l'analyse biochimique, procede de fabrication du dispositif, et systeme d'analyse microfluidique

Publications (2)

Publication Number Publication Date
JP2008502882A JP2008502882A (ja) 2008-01-31
JP4763690B2 true JP4763690B2 (ja) 2011-08-31

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Country Status (9)

Country Link
US (1) US20080110753A1 (fr)
EP (1) EP1781409B1 (fr)
JP (1) JP4763690B2 (fr)
KR (1) KR101179411B1 (fr)
CN (1) CN101031362B (fr)
AT (1) ATE540756T1 (fr)
CA (1) CA2568805C (fr)
FR (1) FR2871150B1 (fr)
WO (1) WO2006003293A2 (fr)

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JP4632300B2 (ja) * 2005-02-14 2011-02-16 国立大学法人 筑波大学 送液装置
JP4893197B2 (ja) * 2006-09-28 2012-03-07 ブラザー工業株式会社 液体移送装置
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EP3181228B1 (fr) 2007-10-02 2020-07-29 Labrador Diagnostics LLC Dispositifs modulaires à utiliser sur place et leurs utilisations
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WO2012040861A1 (fr) * 2010-10-01 2012-04-05 The Governing Council Of The University Of Toronto Dispositifs microfluidiques numériques et procédés d'incorporation d'une phase solide
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JPH10267801A (ja) * 1997-03-24 1998-10-09 Advance Co Ltd 液体微粒子ハンドリング装置
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JP2004061229A (ja) * 2002-07-26 2004-02-26 Hitachi Ltd 感染症検査装置、検査方法、及び感染検査用マイクロファブリケーション
WO2004030820A2 (fr) * 2002-09-24 2004-04-15 Duke University Procedes et appareil de manipulations de gouttelettes par des techniques a base d'electromouillage
JP2006500596A (ja) * 2002-09-24 2006-01-05 デューク・ユニバーシティ エレクトロウェッティング方式の技術を用いて小滴を操作するための方法および装置
JP2005000744A (ja) * 2003-06-10 2005-01-06 Kitakyushu Foundation For The Advancement Of Industry Science & Technology マイクロ液滴輸送デバイス
JP2005257569A (ja) * 2004-03-12 2005-09-22 Kitakyushu Foundation For The Advancement Of Industry Science & Technology 電気的制御可能な微量液滴輸送デバイス
JP2008501944A (ja) * 2004-06-04 2008-01-24 ユニベールシテ・デ・スジャンス・エ・テクノロジー・ドゥ・リル 個別の液滴の形の液体試料を扱い、これによって液滴の化学的および生物学的処理を実施可能とするためのレーザ放射脱離デバイス

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CN101031362A (zh) 2007-09-05
CA2568805A1 (fr) 2006-01-12
EP1781409B1 (fr) 2012-01-11
CN101031362B (zh) 2012-01-11
EP1781409A2 (fr) 2007-05-09
CA2568805C (fr) 2012-08-28
WO2006003293A3 (fr) 2006-09-21
WO2006003293A2 (fr) 2006-01-12
ATE540756T1 (de) 2012-01-15
KR101179411B1 (ko) 2012-09-07
FR2871150A1 (fr) 2005-12-09

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