JP4743673B2 - ポリアミンおよび治療におけるそれらの使用 - Google Patents
ポリアミンおよび治療におけるそれらの使用 Download PDFInfo
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- JP4743673B2 JP4743673B2 JP2000615617A JP2000615617A JP4743673B2 JP 4743673 B2 JP4743673 B2 JP 4743673B2 JP 2000615617 A JP2000615617 A JP 2000615617A JP 2000615617 A JP2000615617 A JP 2000615617A JP 4743673 B2 JP4743673 B2 JP 4743673B2
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- Prior art keywords
- polyamine
- compound
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- black
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- C—CHEMISTRY; METALLURGY
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- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/09—Diamines
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
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- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
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- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/14—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic the nitrogen atom of the amino group being further bound to hydrocarbon groups substituted by amino groups
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
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- C07C45/46—Friedel-Crafts reactions
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
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- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
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- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
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- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
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- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
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- Tropical Medicine & Parasitology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13177999P | 1999-04-30 | 1999-04-30 | |
| US60/131,779 | 1999-04-30 | ||
| PCT/US2000/011591 WO2000066587A2 (en) | 1999-04-30 | 2000-04-27 | Polyamines and their use in therapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011017302A Division JP2011084586A (ja) | 1999-04-30 | 2011-01-28 | ポリアミンおよび治療におけるそれらの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002543202A JP2002543202A (ja) | 2002-12-17 |
| JP2002543202A5 JP2002543202A5 (https=) | 2007-06-07 |
| JP4743673B2 true JP4743673B2 (ja) | 2011-08-10 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000615617A Expired - Fee Related JP4743673B2 (ja) | 1999-04-30 | 2000-04-27 | ポリアミンおよび治療におけるそれらの使用 |
| JP2011017302A Pending JP2011084586A (ja) | 1999-04-30 | 2011-01-28 | ポリアミンおよび治療におけるそれらの使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011017302A Pending JP2011084586A (ja) | 1999-04-30 | 2011-01-28 | ポリアミンおよび治療におけるそれらの使用 |
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| US7030126B2 (en) * | 2001-11-16 | 2006-04-18 | Als Therapy Development Foundation, Inc. | Use of polyamine analogs for amyotrophic lateral sclerosis |
| MXPA04005509A (es) | 2001-12-07 | 2004-12-06 | Slil Biomedical Corp | Poliaminas sustituidas con cicloalquilo para terapia de cancer y metodos de sintesis de las mismas. |
| US20050027016A1 (en) | 2002-02-07 | 2005-02-03 | Fahl Kathleen L | Polyamine compounds and compositions for use in conjection with cancer therapy |
| US6881732B2 (en) * | 2002-06-13 | 2005-04-19 | Chelator Llc | Neuroprotection and cardioprotection afforded by chelators with high affinity and specificity for cations of first transition series elements |
| WO2004002991A1 (en) | 2002-06-26 | 2004-01-08 | Cellgate, Inc. | Porphyrin-polyamine conjugates for cancer therapy |
| US20040019043A1 (en) * | 2002-07-23 | 2004-01-29 | Dimitri Coucouvanis | Thiomolybdate analogues and uses thereof |
| US7189865B2 (en) * | 2002-07-23 | 2007-03-13 | Attenuon, Llc | Thiomolybdate analogues and uses thereof |
| US20040192665A1 (en) * | 2002-08-02 | 2004-09-30 | Slil Biomedical Corporation | Conjugates of porphyrin compounds with chemotherapeutic agents |
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2000
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- 2000-04-27 IL IL14612700A patent/IL146127A0/xx unknown
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- 2000-04-27 MX MXPA01011000A patent/MXPA01011000A/es active IP Right Grant
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- 2001-10-23 IL IL146127A patent/IL146127A/en not_active IP Right Cessation
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|---|---|
| HK1040993B (en) | 2006-11-10 |
| AU2004240213A1 (en) | 2005-01-20 |
| AU2004240213B2 (en) | 2008-11-20 |
| NZ515140A (en) | 2003-07-25 |
| JP2002543202A (ja) | 2002-12-17 |
| BR0010701A (pt) | 2002-02-13 |
| US7186825B2 (en) | 2007-03-06 |
| AU4679900A (en) | 2000-11-17 |
| CA2371625C (en) | 2012-04-17 |
| DE60029944T2 (de) | 2007-04-05 |
| EP1177197A2 (en) | 2002-02-06 |
| MXPA01011000A (es) | 2003-06-30 |
| WO2000066587A2 (en) | 2000-11-09 |
| IL146127A (en) | 2011-11-30 |
| US20070161692A1 (en) | 2007-07-12 |
| EP1698629A3 (en) | 2006-11-29 |
| WO2000066587A3 (en) | 2001-01-25 |
| US6794545B1 (en) | 2004-09-21 |
| IL146127A0 (en) | 2002-07-25 |
| AU2009200547A1 (en) | 2009-03-05 |
| ES2269138T3 (es) | 2007-04-01 |
| DE60029944D1 (de) | 2006-09-21 |
| JP2011084586A (ja) | 2011-04-28 |
| CA2371625A1 (en) | 2000-11-09 |
| ATE335719T1 (de) | 2006-09-15 |
| US20040235962A1 (en) | 2004-11-25 |
| EP1698629A2 (en) | 2006-09-06 |
| EP1177197B1 (en) | 2006-08-09 |
| HK1040993A1 (en) | 2002-06-28 |
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