JP4699997B2 - 脊椎インプラント - Google Patents
脊椎インプラント Download PDFInfo
- Publication number
- JP4699997B2 JP4699997B2 JP2006521937A JP2006521937A JP4699997B2 JP 4699997 B2 JP4699997 B2 JP 4699997B2 JP 2006521937 A JP2006521937 A JP 2006521937A JP 2006521937 A JP2006521937 A JP 2006521937A JP 4699997 B2 JP4699997 B2 JP 4699997B2
- Authority
- JP
- Japan
- Prior art keywords
- spinal implant
- implant
- protrusion
- protrusions
- front side
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/16—Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans
- A61B17/1662—Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans for particular parts of the body
- A61B17/1671—Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans for particular parts of the body for the spine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
- A61F2/4465—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages having a circular or kidney shaped cross-section substantially perpendicular to the axis of the spine
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
- A61F2/4611—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of spinal prostheses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/16—Bone cutting, breaking or removal means other than saws, e.g. Osteoclasts; Drills or chisels for bones; Trepans
- A61B17/1659—Surgical rasps, files, planes, or scrapers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/02—Surgical instruments, devices or methods, e.g. tourniquets for holding wounds open; Tractors
- A61B17/025—Joint distractors
- A61B2017/0256—Joint distractors for the spine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/06—Measuring instruments not otherwise provided for
- A61B2090/062—Measuring instruments not otherwise provided for penetration depth
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
- A61F2002/30059—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis differing in bone mineralization, e.g. made from both mineralized and demineralized adjacent parts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/3008—Properties of materials and coating materials radio-opaque, e.g. radio-opaque markers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
- A61F2002/3011—Cross-sections or two-dimensional shapes
- A61F2002/30112—Rounded shapes, e.g. with rounded corners
- A61F2002/30133—Rounded shapes, e.g. with rounded corners kidney-shaped or bean-shaped
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30108—Shapes
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- A61F2002/30308—Three-dimensional shapes banana-shaped
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
- A61F2002/30537—Special structural features of bone or joint prostheses not otherwise provided for adjustable
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- A61F2002/30604—Special structural features of bone or joint prostheses not otherwise provided for modular
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2002/30784—Plurality of holes
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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- A61F2002/4625—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use
- A61F2002/4627—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use with linear motion along or rotating motion about the instrument axis or the implantation direction, e.g. telescopic, along a guiding rod, screwing inside the instrument
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- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
- A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Transplantation (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Animal Behavior & Ethology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Prostheses (AREA)
Description
Claims (50)
- 脊椎インプラント(100)であって、
遠位端(124)と、
遠位端とは反対側の近位端(122)と、
遠位端と近位端との間に延在しており、少なくとも一部分が第1の椎骨と接触するように形成された上部と、
上部の反対側で遠位端と近位端との間に延在しており、少なくとも一部分が第1の椎骨に隣接する第2の椎骨と接触するように形成された底部と、
前記上部と前記底部との間に延在しており、前記脊椎インプラントの遠位端と近位端との間の第1の湾曲と、前記近位端の近傍で第1の湾曲上に位置して前記上部から前記底部に延在する第1の溝部とを有する、前方側部(116)と、
前記前方側部の反対側で前記上部と前記底部との間に延在しており、前記脊椎インプラントの前記遠位端と前記近位端との間の第2の湾曲と、前記近位端の近傍で第2の湾曲上に位置して前記上部から前記底部に延在する第2の溝部とを有する、後方側部(114)と、
脊椎インプラントを上部から底部まで貫通して延設された開口部(112)と
を備えており、
前記第1の溝部および第2の溝部(120)が前記近位端から等距離に位置しており、第1の湾曲および第2の湾曲が同じ方向を向いている、前記脊椎インプラント。 - 近位端が平らである請求項1に記載の脊椎インプラント。
- 近位端に丸みが付けられている請求項1に記載の脊椎インプラント。
- 遠位端が先細である請求項1に記載の脊椎インプラント。
- 遠位端が湾曲している請求項1に記載の脊椎インプラント。
- 上部が、第1の椎骨と接触するように構成された1つまたは複数の突出部(130、130’)を備えている請求項1に記載の脊椎インプラント。
- 上部が、第1の椎骨と接触するように構成された突出部(130、130’)を備え、また突出部のうちの少なくとも2つは高さまたは形状またはその両方が異なっている請求項1に記載の脊椎インプラント。
- 上部が、第1の椎骨と接触するように構成された突出部(130、130’)を備え、また突出部は、放射状のパターンをなしている請求項1に記載の脊椎インプラント。
- 上部が、第1の椎骨と接触するように構成された突出部(130、130’)を備え、また第1の組の隣り合う突出部の相互間における第1の間隔が、第2の組の隣り合う突出部の相互間における第2の間隔と異なっている請求項1に記載の脊椎インプラント。
- 底部が、第2の椎骨と接触するように構成された1つまたは複数の突出部を備えている請求項1に記載の脊椎インプラント。
- 底部が、第2の椎骨と接触するように構成された突出部を備え、また突出部のうちの少なくとも2つは高さまたは形状またはその両方が異なっている請求項1に記載の脊椎インプラント。
- 底部が、第2の椎骨と接触するように構成された突出部を備え、また突出部が、放射状のパターンをなしている請求項1に記載の脊椎インプラント。
- 底部が、第2の椎骨と接触するように構成された突出部を備え、また第1の組の隣り合う突出部の相互間における第1の間隔が、第2の組の隣り合う突出部の相互間における第2の間隔と異なっている請求項1に記載の脊椎インプラント。
- 前方側部の内側表面が、開口部中に延設された1つまたは複数の突出部(128’)を備え、1つまたは複数の突出部が、インプラントを強化するように構成されている請求項1に記載の脊椎インプラント。
- 後方側部の内側表面が、開口部中に延設された1つまたは複数の突出部(128)を備え、1つまたは複数の突出部が、インプラントを強化するように構成されている請求項1に記載の脊椎インプラント。
- 第1の溝部および第2の溝部が、挿入器具と係合するように構成されている請求項1に記載の脊椎インプラント。
- 遠位端が、挿入器具と係合するように構成された複数の溝部を備える請求項1に記載の脊椎インプラント。
- 前方側部または後方側部またはその両方を貫通して延設された1つまたは複数の開口部(118)をさらに備える請求項1に記載の脊椎インプラント。
- 前方側部を貫通して延設された1つまたは複数の開口部、および後方側部を貫通して延設された1つまたは複数の開口部(118)をさらに備え、前方側部開口部の少なくとも1つが、後方側部開口部の少なくとも1つと位置合せがされ、インプラントを介して骨成長をモニタすることができる請求項1に記載の脊椎インプラント。
- 脊椎インプラントが骨を含む請求項1に記載の脊椎インプラント。
- 脊椎インプラントが、ポリエーテルエーテルケトンを含む請求項1に記載の脊椎インプラント。
- 脊椎インプラントが、X線依存型材料のための1つまたは複数の開口部を備える請求項1に記載の脊椎インプラント。
- 脊椎インプラントが金属を含む請求項1に記載の脊椎インプラント。
- 脊椎インプラントがチタンを含む請求項1に記載の脊椎インプラント。
- 上部が、インプラントと骨との骨統合を促進するように処理される請求項1に記載の脊椎インプラント。
- 上部が、脊椎インプラントと骨との融合を促進するように粗くされる請求項1に記載の脊椎インプラント。
- 開口部が、パッキング材料を受け入れるように形成される請求項1に記載の脊椎インプラント。
- 開口部中に配置される、骨を含むパッキング材料をさらに備える請求項1に記載の脊椎インプラント。
- 開口部中に配置される、合成骨材料を含むパッキング材料をさらに備える請求項1に記載の脊椎インプラント。
- 脊椎インプラント(100)であって、本体を備えており、本体が、
遠位端(124)と、
遠位端とは反対側の近位端(122)と、
遠位端と近位端との間に延在しており、放射状に配置され第1の椎骨と接触するように形成された上部突出部(130、130’)を備える上部と、
上部の反対側で遠位端と近位端との間に延在しており、放射状に配置され第1の椎骨に隣接する第2の椎骨と接触するように形成された底部突出部を備える底部と、
前記本体の前記上部、前記底部、遠位端および近位端の間に延在する、湾曲した前方側部(116)と、
前記湾曲した前方側部の反対側で、前記上部、前記底部、前記遠位端および前記近位端の間にある、湾曲した後方側部(114)と、
前記本体において前記前方側部および前記後方側部上に前記上部から前記底部まで凹部を作っており、前記近位端から等距離に位置している2つの溝部(120)と、
上部から底部まで本体を貫通して延設された開口部(112)と
を備えており、
前方側部および後方側部によって形成される横断面が腎臓形である、前記脊椎インプラント。 - 前方側部近傍の上部突出部が、後方側部近傍の上部突出部より粗くなっている請求項30に記載の脊椎インプラント。
- 前方側部近傍の底部突出部が、後方側部近傍の底部突出部より粗くなっている請求項30に記載の脊椎インプラント。
- 上部突出部のうちの少なくとも2つは高さまたは形状またはその両方が異なる請求項30に記載の脊椎インプラント。
- 第1の組の隣り合う上部突出部の相互間における第1の間隔が、第2の組の隣り合う上部突出部の相互間における第2の間隔と異なっている請求項30に記載の脊椎インプラント。
- 底部突出部のうちの少なくとも2つは高さまたは形状またはその両方が異なる請求項30に記載の脊椎インプラント。
- 第1の組の隣り合う底部突出部の相互間における第1の間隔は、第2の組の隣り合う底部突出部の相互間の第2の間隔と異なっている請求項30に記載の脊椎インプラント。
- 本体の後方側部近傍の上部突出部は、本体の前方側部近傍の上部突出部より大きくなっている請求項30に記載の脊椎インプラント。
- 本体の後方側部近傍の上部突出部は、本体の前方側部近傍の上部突出部より高くなっている請求項30に記載の脊椎インプラント。
- 本体の後方側部近傍の底部突出部は、本体の前方側部近傍の底部突出部より大きくなっている請求項30に記載の脊椎インプラント。
- 本体の後方側部近傍の底部突出部は、本体の前方側部近傍の底部突出部より高くなっている請求項30に記載の脊椎インプラント。
- 脊椎インプラント(100)であって、本体を備えており、本体が、
遠位端(124)と、
遠位端とは反対側の近位端(122)と、
前記遠位端と前記近位端との間の湾曲した前方側部(116)と、
前記湾曲した前方側部の反対側で前記遠位端と前記近位端との間にある、湾曲した後方側部(114)と、
遠位端と近位端との間に延在しており、前記前方側部および前記後方側部の近傍に上部突出部(130、130’)を備え、前方側部近傍の上部突出部が後方側部近傍の上部突出部よりも細かくなっている、上部と、
上部の反対側で遠位端と近位端との間に延在する底部と、
前記本体において前記前方側部および前記後方側部上に前記上部から前記底部まで凹部を作っており、前記近位端から等距離に位置している2つの溝部(120)と、
上部から底部まで本体を貫通して延設された開口部(112)と
を備えており、
本体が腎臓形である、前記脊椎インプラント。 - 底部がさらに前記前方側部および前記後方側部の近傍に底部突出部を備え、前方側部近傍の底部突出部は、後方側部近傍の底部突出部より細かくなっている請求項41に記載の脊椎インプラント。
- 底部がさらに前記前方側部および前記後方側部の近傍に底部突出部を備え、前方側部近傍の底部突出部は、後方側部近傍の底部突出部より粗くなっている請求項41に記載の脊椎インプラント。
- 底部がさらに底部突出部を備え、前方側部近傍の底部突出部が第1の放射状パターンを含み、後方側部近傍の底部突出部が第2の放射状パターンを含む請求項41に記載の脊椎インプラント。
- 前方側部近傍の上部突出部が放射状パターンを含む請求項41に記載の脊椎インプラント。
- 後方側部近傍の上部突出部が放射状パターンを含む請求項41に記載の脊椎インプラント。
- 前方側部または後方側部または前方側部および後方側部の両方を貫通して延設された1つまたは複数の開口部(118)をさらに備える請求項41に記載の脊椎インプラント。
- 前方側部を貫通して延設された1つまたは複数の開口部、および後方側部を貫通して延設された1つまたは複数の開口部(118)をさらに備え、前方側部開口部の少なくとも1つが、後方側部開口部の少なくとも1つと位置合せされ、本体を介して骨成長をモニタすることを可能にする請求項41に記載の脊椎インプラント。
- 第1の湾曲が第2の湾曲と同じである請求項1に記載の脊椎インプラント。
- 第1の湾曲および第2の湾曲が腎臓形の横断面を形成している請求項1に記載の脊椎インプラント。
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US10/633,371 US7806932B2 (en) | 2003-08-01 | 2003-08-01 | Spinal implant |
PCT/US2004/023721 WO2005011539A2 (en) | 2003-08-01 | 2004-07-22 | Spinal implant |
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Also Published As
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EP1653892B1 (en) | 2013-04-17 |
EP1653892A2 (en) | 2006-05-10 |
WO2005011539A2 (en) | 2005-02-10 |
US7806932B2 (en) | 2010-10-05 |
AU2004261160B2 (en) | 2010-06-10 |
CA2534357A1 (en) | 2005-02-10 |
AU2004261160C1 (en) | 2010-10-14 |
CA2534357C (en) | 2012-09-18 |
JP2007501027A (ja) | 2007-01-25 |
WO2005011539A3 (en) | 2005-05-19 |
US20050027360A1 (en) | 2005-02-03 |
US8292959B2 (en) | 2012-10-23 |
AU2004261160A1 (en) | 2005-02-10 |
US20100305706A1 (en) | 2010-12-02 |
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