JP4664373B2 - バイオチップをベースにした核酸結合タンパク質の試験方法 - Google Patents

バイオチップをベースにした核酸結合タンパク質の試験方法 Download PDF

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JP4664373B2
JP4664373B2 JP2007541638A JP2007541638A JP4664373B2 JP 4664373 B2 JP4664373 B2 JP 4664373B2 JP 2007541638 A JP2007541638 A JP 2007541638A JP 2007541638 A JP2007541638 A JP 2007541638A JP 4664373 B2 JP4664373 B2 JP 4664373B2
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nucleic acid
binding protein
kit
capture probe
acid capture
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JP2008520212A (ja
JP2008520212A5 (https=
Inventor
邵威
▲趙▼永超
▲孫義▼民
▲喬継▼英
魏▲華▼江
▲楊衛▼平
周玉祥
程京
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Tsinghua University
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2007541638A 2004-11-18 2004-11-23 バイオチップをベースにした核酸結合タンパク質の試験方法 Expired - Fee Related JP4664373B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNB2004100904233A CN1296492C (zh) 2004-11-18 2004-11-18 一种基于生物芯片检测能结合特异序列的核酸结合蛋白的方法
PCT/CN2004/001340 WO2006053463A1 (en) 2004-11-18 2004-11-23 A testing method of nucleic acid binding protein based on biochip

Publications (3)

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JP2008520212A JP2008520212A (ja) 2008-06-19
JP2008520212A5 JP2008520212A5 (https=) 2011-01-13
JP4664373B2 true JP4664373B2 (ja) 2011-04-06

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JP2007541638A Expired - Fee Related JP4664373B2 (ja) 2004-11-18 2004-11-23 バイオチップをベースにした核酸結合タンパク質の試験方法

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Country Link
US (1) US8680016B2 (https=)
EP (1) EP1816476B1 (https=)
JP (1) JP4664373B2 (https=)
CN (1) CN1296492C (https=)
AT (1) ATE545030T1 (https=)
AU (1) AU2004324960A1 (https=)
CA (1) CA2586408A1 (https=)
WO (1) WO2006053463A1 (https=)

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US8394590B2 (en) 2006-08-02 2013-03-12 California Institute Of Technology Capture agents and related methods and systems for detecting and/or sorting targets
AU2007281479A1 (en) 2006-08-02 2008-02-07 California Institute Of Technology Methods and systems for detecting and/or sorting targets
WO2009012340A2 (en) 2007-07-16 2009-01-22 California Institute Of Technology Microfluidic devices, methods and systems for detecting target molecules
JP2011518553A (ja) * 2008-04-09 2011-06-30 カリフォルニア インスティチュート オブ テクノロジー 標的を検出及び／又は分類する捕捉剤および関連する方法およびシステム
KR101090982B1 (ko) 2009-03-16 2011-12-08 경희대학교 산학협력단 양자점-앱타머 접합체를 이용한 생분석 방법
WO2010124157A1 (en) * 2009-04-24 2010-10-28 Ambit Biosciences Corporation Cellular assay employing detectable protein
PT3489685T (pt) 2011-11-21 2024-01-04 Zoetis Services Llc Amplificação de sinais em imunoensaios de fluxo lateral e relacionados
CN103048463A (zh) * 2012-05-02 2013-04-17 中国科学院广州生物医药与健康研究院 一种基于不同严谨度的用于检测dna结合蛋白的微孔板核酸杂交elisa方法
CN108267581A (zh) 2012-08-24 2018-07-10 耶鲁大学 用于高通量多重检测的系统、装置和方法
CN105960644B (zh) * 2013-10-22 2018-07-10 金圣千 用于生成生物分子和核酸的结合信息的标记物及其制备方法，利用上述标记物的生物分子分析方法及装置
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
CN112782140A (zh) 2014-12-03 2021-05-11 伊索普莱西斯公司 细胞分泌特征的分析和筛选
US11353448B2 (en) 2015-02-13 2022-06-07 California Institute Of Technology Methods and compositions for quantifying metabolites and proteins from single cells
EP4465021A3 (en) 2015-08-04 2025-02-26 Zoetis Services LLC Signal amplification in solution-based plasmonic specific-binding partner assays
EP3510398B1 (en) 2016-09-12 2026-02-25 Isoplexis Corporation System and methods for multiplexed analysis of cellular and other immunotherapeutics
EP4036578A1 (en) 2016-11-11 2022-08-03 Isoplexis Corporation Compositions and methods for the simultaneous genomic, transcriptomic and proteomic analysis of single cells
CN110226084A (zh) 2016-11-22 2019-09-10 伊索普莱克西斯公司 用于细胞捕获的系统、装置和方法，以及其制造方法
WO2018140953A1 (en) * 2017-01-30 2018-08-02 Abaxis, Inc. Solution-based plasmon specific-binding partner assays and metallic nanostructures
EP3963070A4 (en) * 2019-04-30 2023-02-22 Encodia, Inc. METHODS OF PREPARATION OF ANALYTES AND RELATED KITS
CN119731334A (zh) * 2022-12-28 2025-03-28 深圳华大生命科学研究院 检测组合物及蛋白捕获检测方法

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US5449603A (en) * 1989-10-24 1995-09-12 Stratagene Method for hybridizing nucleic acids using single-stranded nucleic acid binding protein
WO1993015226A1 (en) 1992-01-28 1993-08-05 President And Fellows Of Harvard College Method for nucleic acid hybridization using single-stranded dna binding protein
US20030054378A1 (en) * 1997-05-08 2003-03-20 Isao Karube Method for detecting target nucleotide sequence
US20030215821A1 (en) * 1999-04-20 2003-11-20 Kevin Gunderson Detection of nucleic acid reactions on bead arrays
EP1425579A2 (en) * 2000-08-14 2004-06-09 TransGenetics Incorporated Transcription factor target gene discovery
CA2327561A1 (en) * 2000-12-27 2002-06-27 Pierre Rousseau Methods for the screening and/or for the identification of differentially active nucleic acid binding factors of nucleic acid binding elements using dna microarray technology (dpa):dna proteomic array
US20020177218A1 (en) 2001-03-30 2002-11-28 Yu Fang Methods of detecting multiple DNA binding protein and DNA interactions in a sample, and devices, systems and kits for practicing the same
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JP3944576B2 (ja) * 2003-03-28 2007-07-11 独立行政法人産業技術総合研究所 マイクロアレイを用いたアプタマーの取得方法

Also Published As

Publication number Publication date
ATE545030T1 (de) 2012-02-15
US8680016B2 (en) 2014-03-25
AU2004324960A1 (en) 2006-05-26
CA2586408A1 (en) 2006-05-26
CN1296492C (zh) 2007-01-24
US20090018025A1 (en) 2009-01-15
EP1816476B1 (en) 2012-02-08
CN1635165A (zh) 2005-07-06
EP1816476A1 (en) 2007-08-08
JP2008520212A (ja) 2008-06-19
WO2006053463A1 (en) 2006-05-26
EP1816476A4 (en) 2008-08-20

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