JP4648305B2 - フェルラ属植物からフェルチニンを製造する方法 - Google Patents

フェルラ属植物からフェルチニンを製造する方法 Download PDF

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Publication number
JP4648305B2
JP4648305B2 JP2006504815A JP2006504815A JP4648305B2 JP 4648305 B2 JP4648305 B2 JP 4648305B2 JP 2006504815 A JP2006504815 A JP 2006504815A JP 2006504815 A JP2006504815 A JP 2006504815A JP 4648305 B2 JP4648305 B2 JP 4648305B2
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JP
Japan
Prior art keywords
fertinin
ferula
ester
extracted
jaesquekenadiol
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Expired - Fee Related
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JP2006504815A
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Japanese (ja)
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JP2006522043A5 (enExample
JP2006522043A (ja
Inventor
エジオ ボムバルデッリ、
ガブリエリ フォンターナ、
アルド クリストーニ、
エンリコ メルカッリ、
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インデナ エッセ ピ ア
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Publication of JP2006522043A5 publication Critical patent/JP2006522043A5/ja
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/86—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified hydroxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/26—All rings being cycloaliphatic the ring system containing ten carbon atoms
    • C07C2602/30—Azulenes; Hydrogenated azulenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Emergency Medicine (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Toxicology (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2006504815A 2003-04-04 2004-03-23 フェルラ属植物からフェルチニンを製造する方法 Expired - Fee Related JP4648305B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000661A ITMI20030661A1 (it) 2003-04-04 2003-04-04 Processo per la preparazione della ferutinina da piante del genere ferula
PCT/EP2004/003055 WO2004087179A1 (en) 2003-04-04 2004-03-23 A process for the preparation of ferutinine from ferula genus plants

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010106573A Division JP5409505B2 (ja) 2003-04-04 2010-05-06 フェルラ属植物からフェルチニンを製造する方法

Publications (3)

Publication Number Publication Date
JP2006522043A JP2006522043A (ja) 2006-09-28
JP2006522043A5 JP2006522043A5 (enExample) 2010-06-24
JP4648305B2 true JP4648305B2 (ja) 2011-03-09

Family

ID=33105046

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2006504815A Expired - Fee Related JP4648305B2 (ja) 2003-04-04 2004-03-23 フェルラ属植物からフェルチニンを製造する方法
JP2010106573A Expired - Fee Related JP5409505B2 (ja) 2003-04-04 2010-05-06 フェルラ属植物からフェルチニンを製造する方法

Family Applications After (1)

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JP2010106573A Expired - Fee Related JP5409505B2 (ja) 2003-04-04 2010-05-06 フェルラ属植物からフェルチニンを製造する方法

Country Status (19)

Country Link
US (4) US7371886B2 (enExample)
EP (1) EP1615651B1 (enExample)
JP (2) JP4648305B2 (enExample)
KR (2) KR101132526B1 (enExample)
CN (2) CN100518732C (enExample)
AT (1) ATE517631T1 (enExample)
AU (1) AU2004226853B2 (enExample)
BR (1) BRPI0409166B1 (enExample)
CA (2) CA2521100C (enExample)
DK (1) DK1615651T3 (enExample)
ES (1) ES2367361T3 (enExample)
IL (1) IL171230A (enExample)
IT (1) ITMI20030661A1 (enExample)
NO (1) NO333671B1 (enExample)
PL (1) PL1615651T3 (enExample)
PT (1) PT1615651E (enExample)
RU (2) RU2342153C2 (enExample)
SI (1) SI1615651T1 (enExample)
WO (1) WO2004087179A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20032286A1 (it) * 2003-11-24 2005-05-25 Indena Spa Composizioni per il trattamento di dermatiti atopiche di stati allergici cutanei e dell'acne
US8536584B2 (en) 2007-11-14 2013-09-17 Cree, Inc. High voltage wire bond free LEDS
US20100260695A1 (en) * 2009-04-09 2010-10-14 Mary Kay Inc. Combination of plant extracts to improve skin tone
EP2575973B1 (en) * 2010-05-24 2017-06-28 Indena S.p.A. Tamarind seed polysaccharide and ferula hermonis extract for use in the treatment of inflammatory diseases
EP2706995B1 (en) * 2011-05-12 2016-11-30 B.R.A.I.N. Biotechnology Research and Information Network AG Small molecule inhibitors of trpa1
US9913799B2 (en) 2014-07-11 2018-03-13 Mary Kay Inc. Cosmetic compositions and methods of their use
CN105820146A (zh) * 2015-01-08 2016-08-03 辽宁医联新药研究所 一种阿魏内酯及其提取纯化的方法
GB2570508A (en) * 2018-01-30 2019-07-31 Saeed Mohammad Sultan Alaryani Humaid Preparation for treatment of wounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1604225A (en) * 1978-05-15 1981-12-02 Skourides A A Extract of ambelferae for pharmacological use
WO1988009164A1 (fr) * 1987-05-29 1988-12-01 Institut Khimii Rastitelnykh Veschestv Akademii Na Preparation pharmaceutique a action oestrogenique
RU2090198C1 (ru) * 1991-03-12 1997-09-20 Иван Иванович Уваров Способ получения биологически активных веществ, обладающих противогрибковой активностью
DE4444238A1 (de) * 1994-12-13 1996-06-20 Beiersdorf Ag Kosmetische oder dermatologische Wirkstoffkombinationen aus Zimtsäurederivaten und Flavonglycosiden
JP4244093B2 (ja) * 2000-01-24 2009-03-25 三省製薬株式会社 美白化粧料
ATE369868T1 (de) * 2000-06-27 2007-09-15 Qualilife Pharmaceuticals Inc Zusammensetzungen und verfahren zur behandlung der weiblichen sexuellen reaktion
US6623768B1 (en) * 2002-04-16 2003-09-23 Yousry M. A. Naguib Pharmaceutically active composition extracted from Ferula hermonis and process of its extraction

Also Published As

Publication number Publication date
US8247005B2 (en) 2012-08-21
NO20054545D0 (no) 2005-10-03
CA2521100A1 (en) 2004-10-14
RU2342153C2 (ru) 2008-12-27
US7371886B2 (en) 2008-05-13
US8101215B2 (en) 2012-01-24
KR101169893B1 (ko) 2012-07-31
WO2004087179A1 (en) 2004-10-14
JP2010209099A (ja) 2010-09-24
RU2005130639A (ru) 2006-04-27
NO333671B1 (no) 2013-08-05
EP1615651B1 (en) 2011-07-27
EP1615651A1 (en) 2006-01-18
KR20110082091A (ko) 2011-07-15
SI1615651T1 (sl) 2011-11-30
HK1087618A1 (zh) 2006-10-20
JP5409505B2 (ja) 2014-02-05
ES2367361T3 (es) 2011-11-02
CA2766702A1 (en) 2004-10-14
US20120095094A1 (en) 2012-04-19
CN100518732C (zh) 2009-07-29
ATE517631T1 (de) 2011-08-15
RU2469733C2 (ru) 2012-12-20
JP2006522043A (ja) 2006-09-28
KR20060008307A (ko) 2006-01-26
CN101371818A (zh) 2009-02-25
CN1767841A (zh) 2006-05-03
BRPI0409166B1 (pt) 2015-09-01
PT1615651E (pt) 2011-09-02
RU2008122295A (ru) 2009-12-10
IL171230A (en) 2014-02-27
CA2766702C (en) 2015-09-29
US20100255125A1 (en) 2010-10-07
NO20054545L (no) 2005-10-06
CA2521100C (en) 2012-05-01
US20080248139A1 (en) 2008-10-09
ITMI20030661A1 (it) 2004-10-05
PL1615651T3 (pl) 2011-12-30
AU2004226853B2 (en) 2009-06-04
BRPI0409166A (pt) 2006-04-11
AU2004226853A1 (en) 2004-10-14
US20060275246A1 (en) 2006-12-07
KR101132526B1 (ko) 2012-04-03
DK1615651T3 (da) 2011-10-24

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