JP4624673B2 - 化合物の経皮輸送 - Google Patents

化合物の経皮輸送 Download PDF

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Publication number
JP4624673B2
JP4624673B2 JP2003550823A JP2003550823A JP4624673B2 JP 4624673 B2 JP4624673 B2 JP 4624673B2 JP 2003550823 A JP2003550823 A JP 2003550823A JP 2003550823 A JP2003550823 A JP 2003550823A JP 4624673 B2 JP4624673 B2 JP 4624673B2
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JP
Japan
Prior art keywords
group
phosphate
chohch
coox
phosphate ester
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Expired - Fee Related
Application number
JP2003550823A
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English (en)
Japanese (ja)
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JP2005511725A (ja
JP2005511725A5 (https=
Inventor
マイケル ウエスト，サイモン
カナー，デイビッド
Original Assignee
バイタル ヘルス サイエンシズ プロプライアタリー リミティド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPR9463A external-priority patent/AUPR946301A0/en
Priority claimed from AU2002950711A external-priority patent/AU2002950711A0/en
Application filed by バイタル ヘルス サイエンシズ プロプライアタリー リミティド filed Critical バイタル ヘルス サイエンシズ プロプライアタリー リミティド
Publication of JP2005511725A publication Critical patent/JP2005511725A/ja
Publication of JP2005511725A5 publication Critical patent/JP2005511725A5/ja
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Publication of JP4624673B2 publication Critical patent/JP4624673B2/ja
Anticipated expiration legal-status Critical
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Addiction (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2003550823A 2001-12-13 2002-12-13 化合物の経皮輸送 Expired - Fee Related JP4624673B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPR9463A AUPR946301A0 (en) 2001-12-13 2001-12-13 Transdermal therapy
AU2002950711A AU2002950711A0 (en) 2002-08-09 2002-08-09 Transdermal transport of compounds
PCT/AU2002/001686 WO2003049774A1 (en) 2001-12-13 2002-12-13 Transdermal transport of compounds

Publications (3)

Publication Number Publication Date
JP2005511725A JP2005511725A (ja) 2005-04-28
JP2005511725A5 JP2005511725A5 (https=) 2010-07-22
JP4624673B2 true JP4624673B2 (ja) 2011-02-02

Family

ID=25646859

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003550823A Expired - Fee Related JP4624673B2 (ja) 2001-12-13 2002-12-13 化合物の経皮輸送

Country Status (11)

Country Link
US (1) US20050089495A1 (https=)
EP (1) EP1460995B1 (https=)
JP (1) JP4624673B2 (https=)
CN (1) CN1604772A (https=)
AT (1) ATE487456T1 (https=)
AU (1) AU2002350272B1 (https=)
BR (1) BR0215102A (https=)
CA (1) CA2466536C (https=)
DE (1) DE60238276D1 (https=)
MX (1) MXPA04005361A (https=)
WO (1) WO2003049774A1 (https=)

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WO2003011303A1 (en) 2001-07-27 2003-02-13 Vital Health Sciences Pty Ltd Dermal therapy using phosphate derivatives of electron transfer agents
CA2466536C (en) * 2001-12-13 2012-02-07 Vital Health Sciences Pty Ltd Transdermal transport of compounds
AU2002950713A0 (en) * 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
WO2004064831A1 (en) * 2003-01-17 2004-08-05 Vital Health Sciences Pty Ltd Compounds having anti-proliferative properties
AU2003901815A0 (en) * 2003-04-15 2003-05-01 Vital Health Sciences Pty Ltd Phosphate derivatives
AU2003901813A0 (en) * 2003-04-15 2003-05-01 Vital Health Sciences Pty Ltd Pharmaceutical derivatives
DK1720551T3 (da) 2004-03-03 2011-05-16 Vital Health Sciences Pty Ltd Alkaloidformuleringer
CA2575587C (en) * 2004-08-03 2014-06-17 Vital Health Sciences Pty Ltd Carrier for enteral administration
CA2599424A1 (en) * 2005-03-03 2006-09-08 Vital Health Sciences Pty Ltd Compounds having anti-cancer properties
NZ565049A (en) * 2005-06-17 2012-02-24 Vital Health Sciences Pty Ltd A carrier comprising one or more DI and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof
US20090005348A1 (en) * 2005-12-23 2009-01-01 Vital Health Sciences Pty Ltd Compounds Having Cytokine Modulating Properties
JP2007308403A (ja) * 2006-05-17 2007-11-29 Kenji Yoshida 皮膚外用剤
US8491927B2 (en) 2009-12-02 2013-07-23 Nimble Epitech, Llc Pharmaceutical composition containing a hypomethylating agent and a histone deacetylase inhibitor
NZ600773A (en) * 2009-12-23 2014-04-30 Phosphagenics Ltd A carrier for delivery of a biologically active compound
ES2999020T3 (en) 2010-02-05 2025-02-24 Phosphagenics Ltd Carrier comprising non-neutralised tocopheryl phosphate
EP2552486B1 (en) 2010-03-30 2020-08-12 Phosphagenics Limited Transdermal delivery patch
WO2011120070A1 (en) * 2010-03-30 2011-10-06 Phosphagenics Limited Transdermal delivery patch
WO2012122586A1 (en) 2011-03-15 2012-09-20 Phosphagenics Limited New composition
KR20160001419A (ko) * 2014-06-27 2016-01-06 포항공과대학교 산학협력단 양이온성 분자 수송체 및 음이온성 생리활성 물질을 포함하는 피부 투과용 조성물
CN114712308A (zh) 2015-12-09 2022-07-08 磷肌酸有限公司 药物制剂
EP3558903B1 (en) * 2016-12-21 2024-07-03 Avecho Biotechnology Limited Process for phosphorylating a complex alcohol
CN109589331B (zh) * 2019-02-19 2021-02-19 刘晓双 一种抑制术后静脉血栓形成的外用药物及其用途
US12059486B2 (en) 2021-01-13 2024-08-13 Rodan &Fields, LLC Cosmetic compositions

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ATE487456T1 (de) 2010-11-15
MXPA04005361A (es) 2004-09-27
CN1604772A (zh) 2005-04-06
JP2005511725A (ja) 2005-04-28
CA2466536C (en) 2012-02-07
BR0215102A (pt) 2004-11-03
DE60238276D1 (de) 2010-12-23
US20050089495A1 (en) 2005-04-28
AU2002350272B1 (en) 2003-06-23
WO2003049774A1 (en) 2003-06-19
EP1460995A4 (en) 2007-11-21
EP1460995A1 (en) 2004-09-29
EP1460995B1 (en) 2010-11-10

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