JP4608217B2 - 不整脈の治療法 - Google Patents

不整脈の治療法 Download PDF

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Publication number
JP4608217B2
JP4608217B2 JP2003583420A JP2003583420A JP4608217B2 JP 4608217 B2 JP4608217 B2 JP 4608217B2 JP 2003583420 A JP2003583420 A JP 2003583420A JP 2003583420 A JP2003583420 A JP 2003583420A JP 4608217 B2 JP4608217 B2 JP 4608217B2
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JP
Japan
Prior art keywords
ranolazine
compound
isomer
formula
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2003583420A
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English (en)
Japanese (ja)
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JP2005528393A (ja
JP2005528393A5 (pt
Inventor
ルイス・ベラルディネッリ
チャールズ・アンツェレビッチ
ブレント・ブラックバーン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gilead Palo Alto Inc
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Gilead Palo Alto Inc
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Publication of JP2005528393A publication Critical patent/JP2005528393A/ja
Publication of JP2005528393A5 publication Critical patent/JP2005528393A5/ja
Application granted granted Critical
Publication of JP4608217B2 publication Critical patent/JP4608217B2/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2003583420A 2002-04-04 2003-04-04 不整脈の治療法 Expired - Fee Related JP4608217B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US37015002P 2002-04-04 2002-04-04
US40829202P 2002-09-05 2002-09-05
US42258902P 2002-10-30 2002-10-30
PCT/US2003/010434 WO2003086401A1 (en) 2002-04-04 2003-04-04 Use of ranolazine for the preparation of a medicament for the treatment of arrhythmias

Publications (3)

Publication Number Publication Date
JP2005528393A JP2005528393A (ja) 2005-09-22
JP2005528393A5 JP2005528393A5 (pt) 2006-05-11
JP4608217B2 true JP4608217B2 (ja) 2011-01-12

Family

ID=29255318

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003583420A Expired - Fee Related JP4608217B2 (ja) 2002-04-04 2003-04-04 不整脈の治療法

Country Status (20)

Country Link
US (2) US20030220344A1 (pt)
EP (3) EP1930007B1 (pt)
JP (1) JP4608217B2 (pt)
KR (2) KR20100119804A (pt)
CN (2) CN100548300C (pt)
AT (2) ATE397932T1 (pt)
AU (3) AU2003230810B2 (pt)
CA (1) CA2481192C (pt)
CY (1) CY1110400T1 (pt)
DE (2) DE60321550D1 (pt)
DK (2) DK1930007T3 (pt)
ES (2) ES2345573T3 (pt)
HK (1) HK1120390A1 (pt)
IL (1) IL197406A0 (pt)
MX (1) MXPA04009637A (pt)
NO (1) NO330953B1 (pt)
NZ (1) NZ535610A (pt)
PT (2) PT1930007E (pt)
SI (2) SI1490066T1 (pt)
WO (1) WO2003086401A1 (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10925546B2 (en) 2015-01-09 2021-02-23 Industry-Academic Cooperation Foundation Yonsei University System and method for evaluating effects of antiarrhythmic agent

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US20080233191A1 (en) * 2007-03-22 2008-09-25 Brent Blackburn Use of ranolazine for elevated brain-type natriuretic peptide
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WO2014037832A2 (en) 2012-09-06 2014-03-13 Mahesh Kandula Compositions and methods for the treatment of epilepsy and neurological diseases
WO2013167990A1 (en) 2012-05-07 2013-11-14 Mahesh Kandula Compositions and methods for the treatment of depression
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US9765020B2 (en) 2012-05-23 2017-09-19 Cellix Bio Private Limited Dichlorophenyl-imino compounds and compositions, and methods for the treatment of mucositis
CN104603097A (zh) 2012-05-23 2015-05-06 塞利克斯比奥私人有限公司 用于治疗多发性硬化症的组合物和方法
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US9434729B2 (en) 2012-05-23 2016-09-06 Cellix Bio Private Limited Compositions and methods for the treatment of periodontitis and rheumatoid arthritis
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10925546B2 (en) 2015-01-09 2021-02-23 Industry-Academic Cooperation Foundation Yonsei University System and method for evaluating effects of antiarrhythmic agent

Also Published As

Publication number Publication date
DE60332975D1 (de) 2010-07-22
AU2011202135A1 (en) 2011-05-26
NZ535610A (en) 2006-05-26
CA2481192C (en) 2012-07-03
ATE470445T1 (de) 2010-06-15
ES2345573T3 (es) 2010-09-27
EP1930007A1 (en) 2008-06-11
CY1110400T1 (el) 2015-04-29
ATE397932T1 (de) 2008-07-15
JP2005528393A (ja) 2005-09-22
CN100548300C (zh) 2009-10-14
AU2003230810A1 (en) 2003-10-27
AU2009201065A1 (en) 2009-04-09
EP2198866A1 (en) 2010-06-23
DE60321550D1 (de) 2008-07-24
CA2481192A1 (en) 2003-10-23
DK1490066T3 (da) 2008-10-13
AU2009201065B2 (en) 2011-07-21
US20030220344A1 (en) 2003-11-27
ES2304507T3 (es) 2008-10-16
KR20100119804A (ko) 2010-11-10
IL197406A0 (en) 2011-07-31
PT1490066E (pt) 2008-07-22
SI1930007T1 (sl) 2010-08-31
HK1120390A1 (en) 2009-04-03
WO2003086401A1 (en) 2003-10-23
EP1490066A1 (en) 2004-12-29
DK1930007T3 (da) 2010-08-30
CN101843619A (zh) 2010-09-29
PT1930007E (pt) 2010-08-17
NO20044783L (no) 2004-11-03
MXPA04009637A (es) 2005-07-14
US20100004255A1 (en) 2010-01-07
EP1490066B1 (en) 2008-06-11
AU2003230810B2 (en) 2009-02-26
CN1646127A (zh) 2005-07-27
EP1930007B1 (en) 2010-06-09
KR20040099395A (ko) 2004-11-26
SI1490066T1 (sl) 2008-10-31
NO330953B1 (no) 2011-08-22

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