JP4486895B2 - コンタクトレンズを清浄化するための多機能性界面活性剤の使用 - Google Patents
コンタクトレンズを清浄化するための多機能性界面活性剤の使用 Download PDFInfo
- Publication number
- JP4486895B2 JP4486895B2 JP2004563783A JP2004563783A JP4486895B2 JP 4486895 B2 JP4486895 B2 JP 4486895B2 JP 2004563783 A JP2004563783 A JP 2004563783A JP 2004563783 A JP2004563783 A JP 2004563783A JP 4486895 B2 JP4486895 B2 JP 4486895B2
- Authority
- JP
- Japan
- Prior art keywords
- composition
- lens
- poloxamine
- antimicrobial agent
- surfactant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000004094 surface-active agent Substances 0.000 title claims description 27
- 239000000203 mixture Substances 0.000 claims description 73
- 239000000243 solution Substances 0.000 claims description 49
- 238000004140 cleaning Methods 0.000 claims description 42
- 238000000034 method Methods 0.000 claims description 26
- 238000010521 absorption reaction Methods 0.000 claims description 13
- 239000003945 anionic surfactant Substances 0.000 claims description 12
- 229920001987 poloxamine Polymers 0.000 claims description 11
- 239000004599 antimicrobial Substances 0.000 claims description 10
- 150000001875 compounds Chemical class 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- OUDSFQBUEBFSPS-UHFFFAOYSA-N ethylenediaminetriacetic acid Chemical compound OC(=O)CNCCN(CC(O)=O)CC(O)=O OUDSFQBUEBFSPS-UHFFFAOYSA-N 0.000 claims description 9
- IWNZUQBLGWBHIC-UHFFFAOYSA-N 2-[carboxymethyl-[2-[carboxymethyl(dodecanoyl)amino]ethyl]amino]acetic acid Chemical compound CCCCCCCCCCCC(=O)N(CC(O)=O)CCN(CC(O)=O)CC(O)=O IWNZUQBLGWBHIC-UHFFFAOYSA-N 0.000 claims description 6
- 239000007864 aqueous solution Substances 0.000 claims description 5
- 238000011109 contamination Methods 0.000 claims description 5
- 230000000813 microbial effect Effects 0.000 claims description 5
- 239000002736 nonionic surfactant Substances 0.000 claims description 5
- 125000000217 alkyl group Chemical group 0.000 claims description 4
- 125000000129 anionic group Chemical group 0.000 claims description 4
- 125000004432 carbon atom Chemical group C* 0.000 claims description 4
- 125000003342 alkenyl group Chemical group 0.000 claims description 3
- 125000002704 decyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 3
- 125000001400 nonyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 3
- 229920000642 polymer Polymers 0.000 claims description 3
- 239000000872 buffer Substances 0.000 claims description 2
- IFYDWYVPVAMGRO-UHFFFAOYSA-N n-[3-(dimethylamino)propyl]tetradecanamide Chemical compound CCCCCCCCCCCCCC(=O)NCCCN(C)C IFYDWYVPVAMGRO-UHFFFAOYSA-N 0.000 claims description 2
- XNCOSPRUTUOJCJ-UHFFFAOYSA-N Biguanide Chemical compound NC(N)=NC(N)=N XNCOSPRUTUOJCJ-UHFFFAOYSA-N 0.000 claims 2
- 229940123208 Biguanide Drugs 0.000 claims 2
- 150000001450 anions Chemical class 0.000 claims 1
- 230000035699 permeability Effects 0.000 claims 1
- 238000009472 formulation Methods 0.000 description 28
- 102000016943 Muramidase Human genes 0.000 description 20
- 108010014251 Muramidase Proteins 0.000 description 20
- 108010062010 N-Acetylmuramoyl-L-alanine Amidase Proteins 0.000 description 20
- 229960000274 lysozyme Drugs 0.000 description 20
- 235000010335 lysozyme Nutrition 0.000 description 20
- 239000004325 lysozyme Substances 0.000 description 20
- 239000003795 chemical substances by application Substances 0.000 description 13
- 102000004169 proteins and genes Human genes 0.000 description 13
- 108090000623 proteins and genes Proteins 0.000 description 13
- 229940079593 drug Drugs 0.000 description 12
- 239000003814 drug Substances 0.000 description 12
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 11
- 238000000605 extraction Methods 0.000 description 8
- 230000000844 anti-bacterial effect Effects 0.000 description 7
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 239000011780 sodium chloride Substances 0.000 description 6
- 239000003139 biocide Substances 0.000 description 5
- 239000002738 chelating agent Substances 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 238000002156 mixing Methods 0.000 description 5
- 238000002791 soaking Methods 0.000 description 5
- 239000001509 sodium citrate Substances 0.000 description 5
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 5
- DTQVDTLACAAQTR-UHFFFAOYSA-N trifluoroacetic acid Substances OC(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-N 0.000 description 5
- 102000004190 Enzymes Human genes 0.000 description 4
- 108090000790 Enzymes Proteins 0.000 description 4
- 108091005804 Peptidases Proteins 0.000 description 4
- 102000035195 Peptidases Human genes 0.000 description 4
- 239000003242 anti bacterial agent Substances 0.000 description 4
- 230000003115 biocidal effect Effects 0.000 description 4
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 4
- 239000004327 boric acid Substances 0.000 description 4
- 239000008367 deionised water Substances 0.000 description 4
- 229910021641 deionized water Inorganic materials 0.000 description 4
- 230000008021 deposition Effects 0.000 description 4
- 239000003599 detergent Substances 0.000 description 4
- 229940088598 enzyme Drugs 0.000 description 4
- 125000001183 hydrocarbyl group Chemical group 0.000 description 4
- 150000002632 lipids Chemical class 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 239000012085 test solution Substances 0.000 description 4
- OIQXFRANQVWXJF-LIQNAMIISA-N (1s,2z,4r)-2-benzylidene-4,7,7-trimethylbicyclo[2.2.1]heptan-3-one Chemical compound O=C([C@]1(C)CC[C@H]2C1(C)C)\C2=C/C1=CC=CC=C1 OIQXFRANQVWXJF-LIQNAMIISA-N 0.000 description 3
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- 101100162013 Arabidopsis thaliana MAPDA gene Proteins 0.000 description 3
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 3
- 108700015005 N6-mAMP deaminase activity proteins Proteins 0.000 description 3
- 150000001414 amino alcohols Chemical class 0.000 description 3
- 230000000845 anti-microbial effect Effects 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 238000007598 dipping method Methods 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 238000000338 in vitro Methods 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 239000000546 pharmaceutical excipient Substances 0.000 description 3
- 239000002953 phosphate buffered saline Substances 0.000 description 3
- 229920001983 poloxamer Polymers 0.000 description 3
- 239000008213 purified water Substances 0.000 description 3
- 239000000600 sorbitol Substances 0.000 description 3
- 239000011550 stock solution Substances 0.000 description 3
- VTUFDOOSZOYXFC-UHFFFAOYSA-N 2-amino-1-(diaminomethylidene)guanidine Chemical compound NNC(=N)NC(N)=N VTUFDOOSZOYXFC-UHFFFAOYSA-N 0.000 description 2
- 229940058020 2-amino-2-methyl-1-propanol Drugs 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical group CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical compound [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical class OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 description 2
- 229920002413 Polyhexanide Polymers 0.000 description 2
- CBTVGIZVANVGBH-UHFFFAOYSA-N aminomethyl propanol Chemical compound CC(C)(N)CO CBTVGIZVANVGBH-UHFFFAOYSA-N 0.000 description 2
- 229910021538 borax Inorganic materials 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 description 2
- 239000008139 complexing agent Substances 0.000 description 2
- 230000000249 desinfective effect Effects 0.000 description 2
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 230000005284 excitation Effects 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 235000010339 sodium tetraborate Nutrition 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- BSVBQGMMJUBVOD-UHFFFAOYSA-N trisodium borate Chemical compound [Na+].[Na+].[Na+].[O-]B([O-])[O-] BSVBQGMMJUBVOD-UHFFFAOYSA-N 0.000 description 2
- BLXDDKAWAKERQV-HNNXBMFYSA-N (4s)-4-amino-5-dodecoxy-5-oxopentanoic acid Chemical compound CCCCCCCCCCCCOC(=O)[C@@H](N)CCC(O)=O BLXDDKAWAKERQV-HNNXBMFYSA-N 0.000 description 1
- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Polymers CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 description 1
- CYKJOSMQYDEJEO-UHFFFAOYSA-N 2-[(2-dodecoxy-2-oxoethyl)amino]acetic acid Chemical compound CCCCCCCCCCCCOC(=O)CNCC(O)=O CYKJOSMQYDEJEO-UHFFFAOYSA-N 0.000 description 1
- JCBPETKZIGVZRE-UHFFFAOYSA-N 2-aminobutan-1-ol Chemical compound CCC(N)CO JCBPETKZIGVZRE-UHFFFAOYSA-N 0.000 description 1
- -1 Alkyl glutamate Chemical compound 0.000 description 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-M Aminoacetate Chemical compound NCC([O-])=O DHMQDGOQFOQNFH-UHFFFAOYSA-M 0.000 description 1
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 description 1
- BTBUEUYNUDRHOZ-UHFFFAOYSA-N Borate Chemical compound [O-]B([O-])[O-] BTBUEUYNUDRHOZ-UHFFFAOYSA-N 0.000 description 1
- GRHQMTGLVVHYDS-UHFFFAOYSA-N C(C)(=O)O.C(C)(=O)O.C(C)(=O)O.C(CCCCCCCCCCC)NCCN Chemical group C(C)(=O)O.C(C)(=O)O.C(C)(=O)O.C(CCCCCCCCCCC)NCCN GRHQMTGLVVHYDS-UHFFFAOYSA-N 0.000 description 1
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
- 208000001860 Eye Infections Diseases 0.000 description 1
- 102000018697 Membrane Proteins Human genes 0.000 description 1
- 108010052285 Membrane Proteins Proteins 0.000 description 1
- BAVYZALUXZFZLV-UHFFFAOYSA-N Methylamine Chemical compound NC BAVYZALUXZFZLV-UHFFFAOYSA-N 0.000 description 1
- MNLRQHMNZILYPY-MDMHTWEWSA-N N-acetyl-alpha-D-muramic acid Chemical compound OC(=O)[C@@H](C)O[C@H]1[C@H](O)[C@@H](CO)O[C@H](O)[C@@H]1NC(C)=O MNLRQHMNZILYPY-MDMHTWEWSA-N 0.000 description 1
- OVRNDRQMDRJTHS-FMDGEEDCSA-N N-acetyl-beta-D-glucosamine Chemical group CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O OVRNDRQMDRJTHS-FMDGEEDCSA-N 0.000 description 1
- 108010019160 Pancreatin Proteins 0.000 description 1
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 description 1
- UIIMBOGNXHQVGW-DEQYMQKBSA-M Sodium bicarbonate-14C Chemical compound [Na+].O[14C]([O-])=O UIIMBOGNXHQVGW-DEQYMQKBSA-M 0.000 description 1
- 229920002359 Tetronic® Polymers 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 125000002252 acyl group Chemical group 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 229920001400 block copolymer Polymers 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 229960003260 chlorhexidine Drugs 0.000 description 1
- 229940047648 cocoamphodiacetate Drugs 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- XQRLCLUYWUNEEH-UHFFFAOYSA-N diphosphonic acid Chemical compound OP(=O)OP(O)=O XQRLCLUYWUNEEH-UHFFFAOYSA-N 0.000 description 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
- 229910000397 disodium phosphate Inorganic materials 0.000 description 1
- 235000019800 disodium phosphate Nutrition 0.000 description 1
- QKQCPXJIOJLHAL-UHFFFAOYSA-L disodium;2-[2-(carboxylatomethoxy)ethyl-[2-(dodecanoylamino)ethyl]amino]acetate Chemical compound [Na+].[Na+].CCCCCCCCCCCC(=O)NCCN(CC([O-])=O)CCOCC([O-])=O QKQCPXJIOJLHAL-UHFFFAOYSA-L 0.000 description 1
- 231100000673 dose–response relationship Toxicity 0.000 description 1
- 208000011323 eye infectious disease Diseases 0.000 description 1
- 229930195712 glutamate Natural products 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 239000002563 ionic surfactant Substances 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 229940071188 lauroamphodiacetate Drugs 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000004682 monohydrates Chemical class 0.000 description 1
- 229910000403 monosodium phosphate Inorganic materials 0.000 description 1
- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- 230000037125 natural defense Effects 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 125000004433 nitrogen atom Chemical group N* 0.000 description 1
- 229940055695 pancreatin Drugs 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 229960000502 poloxamer Drugs 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 239000006254 rheological additive Substances 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000012475 sodium chloride buffer Substances 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 235000011008 sodium phosphates Nutrition 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/02—Anionic compounds
- C11D1/04—Carboxylic acids or salts thereof
- C11D1/10—Amino carboxylic acids; Imino carboxylic acids; Fatty acid condensates thereof
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/88—Ampholytes; Electroneutral compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/0005—Other compounding ingredients characterised by their effect
- C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Detergent Compositions (AREA)
- Eyeglasses (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43616302P | 2002-12-23 | 2002-12-23 | |
| PCT/US2003/040427 WO2004058929A1 (en) | 2002-12-23 | 2003-12-17 | Use of multifunctional surface active agents to clean contact lenses |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006511837A JP2006511837A (ja) | 2006-04-06 |
| JP2006511837A5 JP2006511837A5 (https=) | 2007-01-25 |
| JP4486895B2 true JP4486895B2 (ja) | 2010-06-23 |
Family
ID=32682353
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004563783A Expired - Lifetime JP4486895B2 (ja) | 2002-12-23 | 2003-12-17 | コンタクトレンズを清浄化するための多機能性界面活性剤の使用 |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US6995123B2 (https=) |
| EP (1) | EP1576081B1 (https=) |
| JP (1) | JP4486895B2 (https=) |
| KR (1) | KR100950132B1 (https=) |
| CN (1) | CN1732255B (https=) |
| AR (1) | AR043317A1 (https=) |
| AT (1) | ATE368098T1 (https=) |
| AU (1) | AU2003301080B2 (https=) |
| BR (1) | BR0317653B1 (https=) |
| CA (1) | CA2507377C (https=) |
| CY (1) | CY1107407T1 (https=) |
| DE (1) | DE60315191T2 (https=) |
| DK (1) | DK1576081T3 (https=) |
| ES (1) | ES2287577T3 (https=) |
| MX (1) | MXPA05006850A (https=) |
| NO (1) | NO337439B1 (https=) |
| NZ (1) | NZ541289A (https=) |
| PT (1) | PT1576081E (https=) |
| TW (1) | TWI322828B (https=) |
| WO (1) | WO2004058929A1 (https=) |
| ZA (1) | ZA200503974B (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8071345B2 (en) * | 2006-03-31 | 2011-12-06 | Novozymes A/S | Stabilized subtilisin composition |
| US20070264226A1 (en) * | 2006-05-10 | 2007-11-15 | Karagoezian Hampar L | Synergistically enhanced disinfecting solutions |
| US8138156B2 (en) * | 2006-10-18 | 2012-03-20 | Bausch & Lomb Incorporated | Ophthalmic compositions containing diglycine |
| US7897553B2 (en) * | 2006-10-23 | 2011-03-01 | Bausch & Lomb Incorporated | Biguanide composition with low terminal amine |
| US8759321B2 (en) * | 2007-06-13 | 2014-06-24 | Bausch & Lomb Incorporated | Ophthalmic composition with hyaluronic acid and polymeric biguanide |
| US20110046033A1 (en) * | 2008-01-31 | 2011-02-24 | Jinzhong Zhang | Multipurpose Lens Care Solution with Benefits to Corneal Epithelial Barrier Function |
| US8119112B2 (en) | 2008-01-31 | 2012-02-21 | Bausch & Lomb Incorporated | Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid |
| US9096819B2 (en) | 2008-01-31 | 2015-08-04 | Bausch & Lomb Incorporated | Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer |
| ES2638771T3 (es) * | 2008-03-17 | 2017-10-24 | Novartis Ag | Composiciones farmacéuticas acuosas que contienen complejos de borato-poliol |
| US8629099B2 (en) * | 2008-03-25 | 2014-01-14 | Bausch & Lomb Incorporated | Ophthalmic compositions comprising a dipeptide |
| TWI489997B (zh) * | 2009-06-19 | 2015-07-01 | Alcon Res Ltd | 含有硼酸－多元醇錯合物之水性藥學組成物 |
| US20110142786A1 (en) * | 2009-09-16 | 2011-06-16 | Erning Xia | Lens care solutions functionalized alkyldimonium hydroxypropyl alkylglucosides |
| US8501200B2 (en) | 2010-04-26 | 2013-08-06 | Bausch & Lomb Incorporated | Ophthalmic compositions with biguanide and PEG-glycerol esters |
| JP5927803B2 (ja) * | 2011-08-05 | 2016-06-01 | 三浦工業株式会社 | 界面活性剤組成物 |
| US11723852B2 (en) | 2011-10-31 | 2023-08-15 | Kane Biotech Inc. | Antimicrobial-antibiofilm compositions and methods of use thereof for personal care products |
| US8664180B2 (en) | 2012-02-06 | 2014-03-04 | Bausch & Lomb Incorporated | Ophthalmic compositions containing diglycine |
| US8324171B1 (en) | 2012-02-06 | 2012-12-04 | Bausch & Lomb Incorporated | Ophthalmic compositions containing diglycine |
| JP2015509495A (ja) | 2012-02-24 | 2015-03-30 | ボシュ・アンド・ロム・インコーポレイテッドＢａｕｓｃｈ ＆ Ｌｏｍｂ Ｉｎｃｏｒｐｏｒａｔｅｄ | アルコキシル化天然ワックスを有する眼用組成物 |
| CN103893027A (zh) * | 2012-12-25 | 2014-07-02 | 青岛海芬海洋生物科技有限公司 | 一种含有海洋生物成分的沐浴液及其制备方法 |
| PL2948196T3 (pl) | 2013-01-24 | 2018-01-31 | Bausch & Lomb | Poli(azotowane/aminowane) pochodne naturalnego wosku lub jego alkoksylowana pochodna i kompozycje okulistyczne |
| JP2017519035A (ja) * | 2014-06-27 | 2017-07-13 | ケーン バイオテク インコーポレーテッド | 抗微生物性−抗バイオフィルム性組成物及び該組成物のパーソナルケア製品のための使用 |
| CN107828545A (zh) * | 2017-10-25 | 2018-03-23 | 成都纽兰晶茂商贸有限公司 | 一种电脑显示屏用清洁剂的制备方法 |
| CN114689538A (zh) * | 2020-12-30 | 2022-07-01 | 苏州三个臭皮匠生物科技有限公司 | 一种有效测量软性亲水角膜接触镜泪蛋白含量的方法 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US441042A (en) * | 1890-11-18 | Policeman s club | ||
| US3908680A (en) | 1973-10-12 | 1975-09-30 | Flow Pharma Inc | Methods for cleaning and bleaching plastic articles |
| US4013576A (en) * | 1973-11-21 | 1977-03-22 | Wesley-Jessen Inc. | Contact lens treating composition |
| US4046706A (en) | 1976-04-06 | 1977-09-06 | Flow Pharmaceuticals, Inc. | Contact lens cleaning composition |
| US4410442A (en) | 1982-01-13 | 1983-10-18 | The Procter & Gamble Company | Disinfecting solutions for hydrophilic contact lenses |
| JPS6151121A (ja) * | 1984-08-21 | 1986-03-13 | Lion Corp | コンタクトレンズ用洗浄剤 |
| US4908147A (en) | 1986-02-19 | 1990-03-13 | Ciba-Geigy Corporation | Aqueous self preserving soft contact lens solution and method |
| US5846919A (en) | 1989-01-31 | 1998-12-08 | Ciba Vision Corporation | Rapid ophthalmic disinfection solution using salt and glycol and/or lower alkanol and surfactant |
| US5298182A (en) | 1989-01-31 | 1994-03-29 | Ciba-Geigy Corporation | Rapid ophthalmic glycol/lower alkanol cleaning and disinfecting solution and method |
| GB9020594D0 (en) * | 1990-09-21 | 1990-10-31 | Procter & Gamble | Cleansing compositions |
| EP0766970A3 (en) | 1990-12-27 | 2000-02-23 | Allergan, Inc | Method and composition for disinfecting contact lenses |
| US5191081A (en) | 1991-12-12 | 1993-03-02 | W. R. Grace & Co.-Conn. | 1-cyanomethyl-4-carboxymethyl-3-ketopiperazine, salts thereof and process for their preparation |
| US5191106A (en) | 1991-12-12 | 1993-03-02 | W. R. Grace & Co.-Conn. | N,n'-diacetic acid-n'-cyanomethyl, salts thereof, and their preparation |
| US5177243A (en) | 1991-12-12 | 1993-01-05 | W. R. Grace & Co.-Conn. | N,N'-diacetic acid-N'-cyanomethyl, salts thereof, and their preparation |
| US5250728A (en) | 1991-12-12 | 1993-10-05 | Hampshire Chemical Corp. | Preparation of ethylenediaminetriacetic acid |
| US5284972A (en) | 1993-06-14 | 1994-02-08 | Hampshire Chemical Corp. | N-acyl-N,N',N'-ethylenediaminetriacetic acid derivatives and process of preparing same |
| US5405878A (en) * | 1993-06-18 | 1995-04-11 | Wilmington Partners L.P. | Contact lens solution containing cationic glycoside |
| US5631005A (en) | 1994-09-21 | 1997-05-20 | Alcon Laboratories, Inc. | Use of amidoamines in ophthalmic compositions |
| US5536452A (en) | 1993-12-07 | 1996-07-16 | Black; Robert H. | Aqueous shower rinsing composition and a method for keeping showers clean |
| US5621008A (en) | 1995-10-27 | 1997-04-15 | Avon Products, Inc. | N-acyl-ethylene-triacetic acids |
| US5858937A (en) | 1996-02-28 | 1999-01-12 | Bausch & Lomb Incorporated | Treatment of contact lenses with aqueous solution including phosphonic compounds |
| US5821215A (en) * | 1996-04-25 | 1998-10-13 | Hampshire Chemical Corp. | N-acyl ethylenediaminetriacetic acid surfactants as enzyme compatible surfactants, stabilizers and activators |
| BR9708777A (pt) | 1996-04-25 | 1999-08-03 | Hampshire Chemical Corp | Composições detergentes ultrabrandas |
| US5688981A (en) * | 1996-11-21 | 1997-11-18 | Hampshire Chemical Corp. | Ethylenediaminetriacetic acid and N-acyl ethylenediaminetriacetic acid silver chelating agents and surfactants |
| JP2001508675A (ja) * | 1996-12-13 | 2001-07-03 | アルコン ラボラトリーズ，インコーポレイテッド | 多目的組成物と、コンタクトレンズ洗浄及び殺菌系への使用方法 |
| PT948357E (pt) | 1996-12-13 | 2002-10-31 | Alcon Lab Inc | Utilizacao de amino alcoois de baixo peso molecular em composicoes oftalmicas |
| US6214596B1 (en) * | 1996-12-18 | 2001-04-10 | Alcon Laboratories, Inc. | Liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems |
| US5869441A (en) | 1997-06-05 | 1999-02-09 | Lever Brothers Company, Division Of Conopco, Inc. | Bar compositions comprising novel chelating surfactants |
| US5801139A (en) | 1997-06-05 | 1998-09-01 | Lever Brothers Company, Division Of Conopco, Inc. | Process for making bar compositions comprising novel chelating surfactants |
| ES2235373T3 (es) | 1997-10-14 | 2005-07-01 | THE PROCTER & GAMBLE COMPANY | Composiciones para limpiar superficies rigidas que comprenden tensioactivos ramificados a mitad de cadena. |
| US5993504A (en) | 1997-11-25 | 1999-11-30 | Hampshire Chemical Corp. | Plant micronutrient chelating surfactant compounds |
| ZA9811445B (en) | 1997-12-19 | 1999-08-16 | Alcon Lab Inc | Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions. |
| EP0976392A1 (en) * | 1998-07-29 | 2000-02-02 | Unilever Plc | Liquid compositions comprising antioxidants and ED3A-derived chelating surfactants as stabilizers |
| US6432893B1 (en) * | 1998-08-21 | 2002-08-13 | Senju Pharmaceutical Co., Ltd. | Method for removal of protein from contact lenses |
| US20020028754A1 (en) | 2000-07-21 | 2002-03-07 | Novozymes A/S | Antimicrobial compositions |
| US6242411B1 (en) * | 2001-01-09 | 2001-06-05 | Colgate-Palmolive Co. | Grease cutting light duty liquid detergent comprising lauryol ethylene diamine triacetate |
| JP2002272819A (ja) * | 2001-03-16 | 2002-09-24 | Tomey Corp | ソフトコンタクトレンズの処理方法 |
| US20040034042A1 (en) | 2002-08-14 | 2004-02-19 | Masao Tsuji | Preservative composition |
-
2003
- 2003-11-05 TW TW092130942A patent/TWI322828B/zh not_active IP Right Cessation
- 2003-12-17 DE DE60315191T patent/DE60315191T2/de not_active Expired - Lifetime
- 2003-12-17 ZA ZA200503974A patent/ZA200503974B/en unknown
- 2003-12-17 NZ NZ541289A patent/NZ541289A/en not_active IP Right Cessation
- 2003-12-17 DK DK03814179T patent/DK1576081T3/da active
- 2003-12-17 PT PT03814179T patent/PT1576081E/pt unknown
- 2003-12-17 BR BRPI0317653-3A patent/BR0317653B1/pt not_active IP Right Cessation
- 2003-12-17 CA CA002507377A patent/CA2507377C/en not_active Expired - Lifetime
- 2003-12-17 AU AU2003301080A patent/AU2003301080B2/en not_active Ceased
- 2003-12-17 EP EP03814179A patent/EP1576081B1/en not_active Expired - Lifetime
- 2003-12-17 KR KR1020057011883A patent/KR100950132B1/ko not_active Expired - Fee Related
- 2003-12-17 CN CN2003801073955A patent/CN1732255B/zh not_active Expired - Lifetime
- 2003-12-17 JP JP2004563783A patent/JP4486895B2/ja not_active Expired - Lifetime
- 2003-12-17 US US10/738,202 patent/US6995123B2/en not_active Expired - Lifetime
- 2003-12-17 WO PCT/US2003/040427 patent/WO2004058929A1/en not_active Ceased
- 2003-12-17 MX MXPA05006850A patent/MXPA05006850A/es active IP Right Grant
- 2003-12-17 AT AT03814179T patent/ATE368098T1/de active
- 2003-12-17 ES ES03814179T patent/ES2287577T3/es not_active Expired - Lifetime
- 2003-12-19 AR ARP030104754A patent/AR043317A1/es not_active Application Discontinuation
-
2005
- 2005-07-22 NO NO20053580A patent/NO337439B1/no not_active IP Right Cessation
- 2005-08-24 US US11/210,331 patent/US20050282715A1/en not_active Abandoned
-
2007
- 2007-08-02 CY CY20071101033T patent/CY1107407T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1576081A1 (en) | 2005-09-21 |
| BR0317653B1 (pt) | 2014-05-27 |
| TWI322828B (en) | 2010-04-01 |
| KR100950132B1 (ko) | 2010-03-30 |
| TW200427473A (en) | 2004-12-16 |
| CY1107407T1 (el) | 2012-12-19 |
| DK1576081T3 (da) | 2007-10-01 |
| CN1732255B (zh) | 2010-08-18 |
| WO2004058929A1 (en) | 2004-07-15 |
| NO20053580L (no) | 2005-07-22 |
| PT1576081E (pt) | 2007-08-10 |
| EP1576081B1 (en) | 2007-07-25 |
| CN1732255A (zh) | 2006-02-08 |
| ATE368098T1 (de) | 2007-08-15 |
| ES2287577T3 (es) | 2007-12-16 |
| AU2003301080B2 (en) | 2010-01-14 |
| MXPA05006850A (es) | 2005-08-16 |
| ZA200503974B (en) | 2006-08-30 |
| DE60315191T2 (de) | 2007-11-22 |
| US6995123B2 (en) | 2006-02-07 |
| CA2507377C (en) | 2008-02-19 |
| US20050282715A1 (en) | 2005-12-22 |
| JP2006511837A (ja) | 2006-04-06 |
| KR20050089981A (ko) | 2005-09-09 |
| AU2003301080A1 (en) | 2004-07-22 |
| CA2507377A1 (en) | 2004-07-15 |
| BR0317653A (pt) | 2005-11-29 |
| HK1075464A1 (en) | 2005-12-16 |
| AR043317A1 (es) | 2005-07-27 |
| NZ541289A (en) | 2008-05-30 |
| DE60315191D1 (de) | 2007-09-06 |
| US20040127372A1 (en) | 2004-07-01 |
| NO337439B1 (no) | 2016-04-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4486895B2 (ja) | コンタクトレンズを清浄化するための多機能性界面活性剤の使用 | |
| US4820352A (en) | Cleaning and conditioning solutions for contact lenses and methods of use | |
| EP2171025B1 (en) | Ophthalmic composition with hyaluronic acid | |
| JPS6185301A (ja) | コンタクトレンズの消毒保存用溶液 | |
| JP2001522673A (ja) | ポリクォーターニウムおよび重合ビグアニドを用いるコンタクトレンズの消毒 | |
| JP2004512904A (ja) | 防腐剤増強剤として単純糖類を含有する改良眼科用およびコンタクトレンズ用溶液 | |
| EP0909808B1 (en) | Process for cleaning and disinfecting contact lenses | |
| US4908147A (en) | Aqueous self preserving soft contact lens solution and method | |
| US20100086514A1 (en) | Contact Lens Care Solutions with a Low Molecular Weight Oligomer | |
| JP2005513546A (ja) | コンタクトレンズを処理するための組成物 | |
| JP2005513112A (ja) | 眼の中でコンタクトレンズを処置するための組成物 | |
| ES2428496T3 (es) | Composiciones oftálmicas con biguanida y ésteres de PEG-glicerol | |
| JP5068763B2 (ja) | レンズケア組成物 | |
| EP1792972A1 (en) | Use of multifuctional surface active agents to clean contact lenses | |
| HK1075464B (en) | Use of multifunctional surface active agents to clean contact lenses | |
| JP2000347141A (ja) | 含水性コンタクトレンズ用処理液 | |
| JPH11290429A (ja) | コンタクトレンズの消毒洗浄保存溶液及び消毒洗浄方法 | |
| HK1018076B (en) | Process for cleaning and disinfecting contact lenses | |
| JP2000292754A (ja) | コンタクトレンズのケア用溶液 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20061201 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20061201 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20090807 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20091106 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20091113 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20091207 |
|
| A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20091214 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20091228 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20100126 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20100224 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20100319 |
|
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20100329 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 4486895 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20130402 Year of fee payment: 3 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20130402 Year of fee payment: 3 |
|
| FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20140402 Year of fee payment: 4 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313113 Free format text: JAPANESE INTERMEDIATE CODE: R313111 |
|
| S531 | Written request for registration of change of domicile |
Free format text: JAPANESE INTERMEDIATE CODE: R313531 |
|
| S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313111 Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
| S531 | Written request for registration of change of domicile |
Free format text: JAPANESE INTERMEDIATE CODE: R313531 |
|
| R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
| S111 | Request for change of ownership or part of ownership |
Free format text: JAPANESE INTERMEDIATE CODE: R313111 Free format text: JAPANESE INTERMEDIATE CODE: R313113 |
|
| S531 | Written request for registration of change of domicile |
Free format text: JAPANESE INTERMEDIATE CODE: R313531 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| EXPY | Cancellation because of completion of term |