JP4400566B2 - ベンズアミド誘導体又はその塩 - Google Patents

ベンズアミド誘導体又はその塩 Download PDF

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JP4400566B2
JP4400566B2 JP2005506991A JP2005506991A JP4400566B2 JP 4400566 B2 JP4400566 B2 JP 4400566B2 JP 2005506991 A JP2005506991 A JP 2005506991A JP 2005506991 A JP2005506991 A JP 2005506991A JP 4400566 B2 JP4400566 B2 JP 4400566B2
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lower alkyl
alkylene
ring
monocyclic
group
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JPWO2004110986A1 (ja
Inventor
孝博 倉持
範夫 朝井
和弘 生貝
清二郎 赤松
博規 原田
典子 石川
昇平 白神
聡 宮本
俊博 渡辺
哲男 木曽
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Astellas Pharma Inc
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Astellas Pharma Inc
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/40—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to a carbon atom of a six-membered aromatic ring
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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