JP4361980B2 - サンプルの潜在的抗血液凝固能の測定法 - Google Patents
サンプルの潜在的抗血液凝固能の測定法 Download PDFInfo
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- JP4361980B2 JP4361980B2 JP31551198A JP31551198A JP4361980B2 JP 4361980 B2 JP4361980 B2 JP 4361980B2 JP 31551198 A JP31551198 A JP 31551198A JP 31551198 A JP31551198 A JP 31551198A JP 4361980 B2 JP4361980 B2 JP 4361980B2
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- thrombomodulin
- protein
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/745—Assays involving non-enzymic blood coagulation factors
- G01N2333/7452—Thrombomodulin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
- G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
- G01N2333/96461—Protein C (3.4.21.69)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Neurosurgery (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19749197A DE19749197A1 (de) | 1997-11-07 | 1997-11-07 | Verfahren zur Bestimmung des antikoagulatorischen Potentials einer Probe |
| DE19749197:9 | 1997-11-07 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPH11225796A JPH11225796A (ja) | 1999-08-24 |
| JPH11225796A5 JPH11225796A5 (enExample) | 2005-12-08 |
| JP4361980B2 true JP4361980B2 (ja) | 2009-11-11 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP31551198A Expired - Fee Related JP4361980B2 (ja) | 1997-11-07 | 1998-11-06 | サンプルの潜在的抗血液凝固能の測定法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20020019021A1 (enExample) |
| EP (1) | EP0915340B1 (enExample) |
| JP (1) | JP4361980B2 (enExample) |
| AT (1) | ATE315233T1 (enExample) |
| AU (1) | AU751525B2 (enExample) |
| CA (1) | CA2252983C (enExample) |
| DE (2) | DE19749197A1 (enExample) |
| ES (1) | ES2255121T3 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0947585T3 (da) * | 1998-03-19 | 2001-10-01 | Instrumentation Lab Spa | Forbedret in vitro-fremgangsmåde, kits og reagenser til screening for blodkoagulationsdefekter |
| WO2001098782A1 (fr) * | 2000-06-22 | 2001-12-27 | Mochida Pharmaceutical Co., Ltd | Kit de determination du pouvoir de coagulation du sang |
| US6432658B1 (en) * | 2000-09-13 | 2002-08-13 | Affinity Biologicals, Inc. | Method for measuring antithrombin activity |
| US6448024B1 (en) | 2000-10-03 | 2002-09-10 | Roche Diagnostics Corporation | Method, reagent, cartridge, and device for determining fibrinogen |
| US6743596B1 (en) | 2000-10-27 | 2004-06-01 | Biomerieux, Inc. | Method of determining global coagulability hemostatic potential |
| US6645768B1 (en) | 2000-10-27 | 2003-11-11 | Biomerieux, Inc. | Reagent and kit for determining global coagulability and hemostatic potential |
| EP1367135A1 (en) * | 2002-05-29 | 2003-12-03 | Pentapharm AG | Improved method for the assessment of thrombin formation in blood or plasma |
| WO2005031303A2 (en) * | 2003-09-22 | 2005-04-07 | University Of North Carolina At Chapel Hill | Soluble phospholipids for use in clotting factor assays |
| US20050221414A1 (en) * | 2004-03-31 | 2005-10-06 | Katalin Varadi | Kit for measuring the thrombin generation in a sample of a patient's blood or plasma |
| US7148067B2 (en) * | 2004-08-31 | 2006-12-12 | The Board Of Trustees Of The University Of Illinois | Thromboplastin reagents |
| WO2006088741A2 (en) * | 2005-02-16 | 2006-08-24 | The Board Of Trustees Of The University Of Illinois | Procoagulants based on metal-chelating lipids |
| EP1869082B1 (en) * | 2005-03-04 | 2011-04-13 | The Board Of Trustees Of The University Of Illinois | Coagulation and fibrinolytic cascades modulator |
| GB2433592A (en) * | 2005-12-23 | 2007-06-27 | Pentapharm Ag | Assay for thrombin inhibitors |
| WO2009046194A2 (en) | 2007-10-05 | 2009-04-09 | The Board Of Trustees Of The University Of Illinois | Fibrin sealant |
| WO2009061697A1 (en) | 2007-11-09 | 2009-05-14 | The Board Of Trustees Of The University Of Illinois | Anticoagulant antagonist and hemophilia procoagulant |
| JP2009198506A (ja) * | 2009-04-10 | 2009-09-03 | Shino Test Corp | 血液凝固反応抑制血漿タンパク質の活性測定方法及び活性測定試薬 |
| EP2619540B1 (en) * | 2010-09-20 | 2018-03-21 | Q-Sera Pty Ltd | Serum preparation |
| JP5818299B2 (ja) * | 2010-12-27 | 2015-11-18 | 国立大学法人名古屋大学 | 凝固因子として作用する異常トロンビンのためのトロンビン不活化動態測定方法 |
| CN103688177B (zh) * | 2011-06-17 | 2017-07-04 | 学校法人东日本学园 | 狼疮抗凝物检测用血液凝固时间的测定方法 |
| WO2014020183A1 (de) | 2012-08-03 | 2014-02-06 | Ici Immunochemical Intelligence Gmbh | In-vitro-assay zur diagnose von störungen der hämostase |
| CN104374621A (zh) * | 2014-11-03 | 2015-02-25 | 温州市倍可特医疗器械有限公司 | 用于血液采集容器的血液促凝剂及其制备方法和应用 |
| WO2016172291A1 (en) * | 2015-04-23 | 2016-10-27 | Fermi Research Alliance, Llc | Monocrystal-based microchannel plate image intensifier |
| JP7170714B2 (ja) | 2018-04-04 | 2022-11-14 | 三菱電機株式会社 | 赤外線固体撮像装置 |
| EP4269605A4 (en) * | 2020-12-28 | 2024-11-20 | Fujimori Kogyo Co., Ltd. | BLOOD COAGULATION INSPECTION PROCEDURES |
| CN115219292B (zh) * | 2022-06-09 | 2025-09-30 | 常熟常江生物技术有限公司 | 全自动血栓弹力图仪质控品及其制备方法、应用方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5221614A (en) * | 1988-03-03 | 1993-06-22 | Nippon Shoji Kabushiki Kaisha | Method and reagent for determining the biological activity of antithrombin III by measuring coagulation time |
| US5202421A (en) * | 1988-12-27 | 1993-04-13 | Mochida Pharmaceutical Co., Ltd. | Anticoagulant substance obtained from urine and process for the preparation thereof |
| US5486599A (en) * | 1989-03-29 | 1996-01-23 | The Board Of Trustees Of The Leland Stanford Junior University | Construction and use of synthetic constructs encoding syndecan |
| US6063763A (en) * | 1989-04-28 | 2000-05-16 | Schering Aktiengesellschaft | Protease-resistant thrombomodulin analogs |
| US5051357A (en) * | 1989-07-14 | 1991-09-24 | Board Of Trustees Operating Michigan State University | Method and assay using inactivation of factors Va and VIIIa by activated Protein C to diagnose thrombic disease or assay for Protein C and kit therefor |
| AU6403590A (en) * | 1989-09-25 | 1991-04-18 | Asahi Kasei Kogyo Kabushiki Kaisha | Isolated, physiologically active human thrombomodulin polypeptide |
| ES2170747T3 (es) * | 1990-08-15 | 2002-08-16 | Paion Gmbh | Analogos superiores de trombomodulina para uso farmaceutico. |
| IL100093A0 (en) * | 1990-11-30 | 1992-08-18 | Kowa Co | Thrombin-binding substance and process for preparing the same |
| US5273962A (en) * | 1990-11-30 | 1993-12-28 | Kowa Co., Ltd. | Human urinary thrombomodulin with a modified glycosaminoglycan (GAG) binding site |
| AU2870992A (en) * | 1991-10-04 | 1993-05-03 | Board Of Regents Of The University Of Nebraska, The | A soluble thrombomodulin-based one-stage assay for vitamin k-dependent coagulation-inhibiting proteins |
| SE470274B (sv) * | 1991-11-13 | 1993-12-20 | Bjoern Dahlbaeck | Användning av en in vitro-metod för diagnos av blodkoagulationssjukdomar |
| FR2689640B1 (fr) * | 1992-04-06 | 1997-08-08 | Bio Merieux | Procede pour la determination d'une activite proteine c et/ou proteine s dans un echantillon plasmatique. |
| DE4229933A1 (de) * | 1992-09-08 | 1994-03-10 | Max Planck Gesellschaft | Verfahren zur Bestimmung von Thrombose verursachenden Lupus-anticoagulant-Antikörpern |
| DE4427785A1 (de) * | 1994-08-08 | 1996-02-15 | Behringwerke Ag | Verfahren zum Nachweis von Störungen des Protein C/Protein S-Systems |
| EP0711838B2 (de) * | 1994-11-10 | 2007-06-20 | Dade Behring Marburg GmbH | Verfahren zum spezifischen Nachweis eines aktivierten Gerinnungsfaktors V mit einer erhöhten Stabilität gegenüber aktiviertem Protein C |
-
1997
- 1997-11-07 DE DE19749197A patent/DE19749197A1/de not_active Ceased
-
1998
- 1998-10-07 EP EP98118971A patent/EP0915340B1/de not_active Expired - Lifetime
- 1998-10-07 ES ES98118971T patent/ES2255121T3/es not_active Expired - Lifetime
- 1998-10-07 DE DE59813326T patent/DE59813326D1/de not_active Expired - Lifetime
- 1998-10-07 AT AT98118971T patent/ATE315233T1/de active
- 1998-11-06 US US09/187,035 patent/US20020019021A1/en not_active Abandoned
- 1998-11-06 AU AU91397/98A patent/AU751525B2/en not_active Ceased
- 1998-11-06 JP JP31551198A patent/JP4361980B2/ja not_active Expired - Fee Related
- 1998-11-06 CA CA2252983A patent/CA2252983C/en not_active Expired - Fee Related
-
2003
- 2003-04-21 US US10/419,104 patent/US20030207343A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20020019021A1 (en) | 2002-02-14 |
| EP0915340B1 (de) | 2006-01-04 |
| AU751525B2 (en) | 2002-08-22 |
| CA2252983A1 (en) | 1999-05-07 |
| JPH11225796A (ja) | 1999-08-24 |
| DE19749197A1 (de) | 1999-05-12 |
| ATE315233T1 (de) | 2006-02-15 |
| CA2252983C (en) | 2010-07-13 |
| EP0915340A1 (de) | 1999-05-12 |
| US20030207343A1 (en) | 2003-11-06 |
| ES2255121T3 (es) | 2006-06-16 |
| AU9139798A (en) | 1999-05-27 |
| DE59813326D1 (de) | 2006-03-30 |
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