JP4288156B2 - 充填用に回転かつ注射用にプル・プッシュ形式の投薬装置 - Google Patents
充填用に回転かつ注射用にプル・プッシュ形式の投薬装置 Download PDFInfo
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- JP4288156B2 JP4288156B2 JP2003513626A JP2003513626A JP4288156B2 JP 4288156 B2 JP4288156 B2 JP 4288156B2 JP 2003513626 A JP2003513626 A JP 2003513626A JP 2003513626 A JP2003513626 A JP 2003513626A JP 4288156 B2 JP4288156 B2 JP 4288156B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2485—Ampoule holder connected to rest of syringe
- A61M2005/2488—Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3123—Details having air entrapping or venting means, e.g. purging channels in pistons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3146—Priming, e.g. purging, reducing backlash or clearance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31543—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31555—Mechanically operated dose setting member by purely axial movement of dose setting member, e.g. during setting or filling of a syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31561—Mechanically operated dose setting member using freely adjustable volume steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
- A61M5/31595—Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Description
Claims (9)
- 薬物投薬装置(20、220)であって:
ハウジング(60、250);
上記ハウジングに対して装着された流体コンテナーであって、上記コンテナーが薬物充満リザーバーを区画している、流体コンテナー;
上記流体コンテナーの先端に対して取り外し可能に装着された針アセンブリー(38)であって、上記針アセンブリーの注射針(40)が上記リザーバーと流体的に連通している、針アセンブリー;
上記リザーバーから上記注射針を通して薬剤服用量投薬のための駆動機構であって、上記駆動機構が、装置を準備完了状態からコック状態へとシフトするために、上記ハウジングに対して基端方向に手動でプル可能なプランジャー(160、360)を備えており、上記プランジャーが、装置がコック状態から準備完了状態へと戻る間に上記注射針外に薬剤を押し出すために、上記ハウジングに対して先端方向に手動で押すことができる、駆動機構;
上記注射針に上記リザーバーから薬剤をプライミングするためのプライミング機構であって、上記プライミング機構が、上記ハウジングの外側に上記ハウジングに対して手動で回転可能な駆動部分(102)を備えている、プライミング機構;および
上記プライミング機構駆動部分の手動回転を、第1方向へ、かつプライミング達成に必要なだけ、許容し、かつ、上記第1方向とは反対方向への上記プライミング機構駆動部分の手動回転を阻止する、回転制御機構(68、106、108、280)、
を包含している薬物投薬装置。 - 上記プライミング機構駆動部分が、上記プランジャーと近接し、かつ、上記プランジャーとは独立に操作可能である、請求項1の薬物投薬装置。
- 上記回転制御機構が、上記ハウジングと上記プライミング機構との間で作用するラチェット爪(288)およびラチェット歯(263)を備えている、請求項1の薬物投薬装置。
- 上記プライミング機構は、上記装置がコック状態か準備完了状態かに拘わらず、かつ、上記装置がコック状態にある場合には駆動機構により投薬される服用量を変えることなく、プライミングを達成するように構成されている、請求項1の薬物投薬装置。
- 上記プライミング機構が、ねじ部分および相対回転不能駆動ねじを包含し、
上記ねじ部分が、上記ハウジングに対して内側にあり、かつ、上記プライミング機構駆動部分に対して回転不能であり、
上記ねじ部分が、上記駆動ねじの外ねじと噛合しており、
これにより上記プライミング機構駆動部分の回転が、上記ねじ部分を回転して、上記駆動ねじを先端側へ移行させ、かつ、リザーバーから薬物を押し出す、請求項1の薬物投薬装置。 - 上記ねじ部分が、上記プライミング機構駆動部分と一体に形成されている複数の半径方向に弾性的な指を包含している、請求項5の薬物投薬装置。
- 上記駆動機構が、フォロアーおよび相対回転不能な駆動ねじを包含し、
上記プランジャーが、互いに軸方向に固定されるが相互の回転は許容されるように、上記フォロアーに連結されており、
上記フォロアーが、上記ハウジングに対して内側にあり、かつ、上記駆動ねじの外ねじに噛合する、ねじ部分を、備えている、請求項1の薬物投薬装置。 - 上記フォロアーの上記ねじ部分が、半径方向に弾性的な複数の指(146、300)を包含している、請求項7の薬物投薬装置。
- 上記流体コンテナーが、取り替えのために装置から取り外し可能な使い捨てカートリッジを包含し、かつ、更に上記駆動機構をリセットするための手段を包含しており、これによって取り替えカートリッジを用いて薬物投薬装置を再使用することができる、請求項1の薬物投薬装置。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30573301P | 2001-07-16 | 2001-07-16 | |
US35423702P | 2002-02-04 | 2002-02-04 | |
PCT/US2002/019815 WO2003008023A1 (en) | 2001-07-16 | 2002-07-15 | Medication dispensing apparatus configured for rotate to prime and pull/push to inject functionality |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009027242A Division JP4799627B2 (ja) | 2001-07-16 | 2009-02-09 | プライミング用に回転し、且つ、注射機能用に引いて/押す薬物投薬装置 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2004535255A JP2004535255A (ja) | 2004-11-25 |
JP4288156B2 true JP4288156B2 (ja) | 2009-07-01 |
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ID=26974753
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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JP2003513626A Expired - Fee Related JP4288156B2 (ja) | 2001-07-16 | 2002-07-15 | 充填用に回転かつ注射用にプル・プッシュ形式の投薬装置 |
JP2009027242A Expired - Fee Related JP4799627B2 (ja) | 2001-07-16 | 2009-02-09 | プライミング用に回転し、且つ、注射機能用に引いて/押す薬物投薬装置 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
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JP2009027242A Expired - Fee Related JP4799627B2 (ja) | 2001-07-16 | 2009-02-09 | プライミング用に回転し、且つ、注射機能用に引いて/押す薬物投薬装置 |
Country Status (9)
Country | Link |
---|---|
US (2) | US20040236285A1 (ja) |
EP (2) | EP1495777A3 (ja) |
JP (2) | JP4288156B2 (ja) |
AT (1) | ATE289834T1 (ja) |
AU (1) | AU2002345785B2 (ja) |
CA (1) | CA2448726C (ja) |
DE (1) | DE60203118T2 (ja) |
ES (1) | ES2236532T3 (ja) |
WO (1) | WO2003008023A1 (ja) |
Families Citing this family (138)
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DE10232410B4 (de) * | 2002-07-17 | 2006-12-21 | Tecpharma Licensing Ag | Verabreichungsgerät mit Dosisanzeige |
ATE502665T1 (de) * | 2003-02-04 | 2011-04-15 | Novo Nordisk As | Injektionsvorrichtung mit drehbarer dosiseinstellungsvorrichtung |
WO2004094823A2 (en) | 2003-04-23 | 2004-11-04 | Biovalve Technologies, Inc. | Hydraulically actuated pump for long duration medicament administration |
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EP1541185A1 (en) * | 2003-12-08 | 2005-06-15 | Novo Nordisk A/S | Automatic syringe with priming mechanism |
DE102004004310A1 (de) * | 2004-01-28 | 2005-08-18 | Tecpharma Licensing Ag | Injektionsgerät mit verrastbarem Dosierglied |
ME03411B (me) | 2004-03-30 | 2020-01-20 | Lilly Co Eli | Naprava za izdavanje lijeka sa blokirajućom karakterisтikom pogonjenom oprugom akтiviranom davanjem posljednje doze |
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2002
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- 2002-07-15 AT AT02744534T patent/ATE289834T1/de not_active IP Right Cessation
- 2002-07-15 JP JP2003513626A patent/JP4288156B2/ja not_active Expired - Fee Related
- 2002-07-15 WO PCT/US2002/019815 patent/WO2003008023A1/en active IP Right Grant
- 2002-07-15 ES ES02744534T patent/ES2236532T3/es not_active Expired - Lifetime
- 2002-07-15 CA CA2448726A patent/CA2448726C/en not_active Expired - Fee Related
- 2002-07-15 US US10/483,976 patent/US20040236285A1/en not_active Abandoned
- 2002-07-15 DE DE60203118T patent/DE60203118T2/de not_active Expired - Lifetime
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EP1495777A2 (en) | 2005-01-12 |
DE60203118D1 (de) | 2005-04-07 |
JP2009153985A (ja) | 2009-07-16 |
DE60203118T2 (de) | 2006-04-13 |
ES2236532T3 (es) | 2005-07-16 |
EP1495777A3 (en) | 2007-01-03 |
AU2002345785B2 (en) | 2007-11-15 |
US7704237B2 (en) | 2010-04-27 |
CA2448726C (en) | 2012-01-31 |
EP1409046A1 (en) | 2004-04-21 |
JP2004535255A (ja) | 2004-11-25 |
CA2448726A1 (en) | 2003-01-30 |
ATE289834T1 (de) | 2005-03-15 |
US20040236285A1 (en) | 2004-11-25 |
WO2003008023A1 (en) | 2003-01-30 |
EP1409046B1 (en) | 2005-03-02 |
JP4799627B2 (ja) | 2011-10-26 |
US20070142789A1 (en) | 2007-06-21 |
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