JP4135905B2 - 清涼化剤を含有するコンタクトレンズ用点眼剤 - Google Patents
清涼化剤を含有するコンタクトレンズ用点眼剤 Download PDFInfo
- Publication number
- JP4135905B2 JP4135905B2 JP2003071181A JP2003071181A JP4135905B2 JP 4135905 B2 JP4135905 B2 JP 4135905B2 JP 2003071181 A JP2003071181 A JP 2003071181A JP 2003071181 A JP2003071181 A JP 2003071181A JP 4135905 B2 JP4135905 B2 JP 4135905B2
- Authority
- JP
- Japan
- Prior art keywords
- menthol
- oxygen
- poe
- contact lenses
- surfactant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003889 eye drop Substances 0.000 title claims description 54
- 229940012356 eye drops Drugs 0.000 title claims description 25
- 239000002826 coolant Substances 0.000 title claims description 10
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- 239000004094 surface-active agent Substances 0.000 claims description 19
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 15
- 238000000034 method Methods 0.000 claims description 15
- 239000003795 chemical substances by application Substances 0.000 claims description 13
- 229940041616 menthol Drugs 0.000 claims description 13
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 12
- 229910052760 oxygen Inorganic materials 0.000 claims description 12
- 239000001301 oxygen Substances 0.000 claims description 12
- 239000000203 mixture Substances 0.000 claims description 9
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims description 8
- 229920001400 block copolymer Polymers 0.000 claims description 6
- JNYAEWCLZODPBN-JGWLITMVSA-N (2r,3r,4s)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol Chemical compound OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O JNYAEWCLZODPBN-JGWLITMVSA-N 0.000 claims description 5
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- NOOLISFMXDJSKH-AEJSXWLSSA-N (+)-menthol Chemical compound CC(C)[C@H]1CC[C@H](C)C[C@@H]1O NOOLISFMXDJSKH-AEJSXWLSSA-N 0.000 claims description 2
- NFLGAXVYCFJBMK-UHFFFAOYSA-N isomenthone Natural products CC(C)C1CCC(C)CC1=O NFLGAXVYCFJBMK-UHFFFAOYSA-N 0.000 claims description 2
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- 229930008380 camphor Natural products 0.000 claims 6
- 238000004519 manufacturing process Methods 0.000 claims 2
- ZORQXIQZAOLNGE-UHFFFAOYSA-N 1,1-difluorocyclohexane Chemical compound FC1(F)CCCCC1 ZORQXIQZAOLNGE-UHFFFAOYSA-N 0.000 claims 1
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- 230000000052 comparative effect Effects 0.000 description 7
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- 238000010998 test method Methods 0.000 description 3
- 239000002562 thickening agent Substances 0.000 description 3
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 2
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- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 2
- 206010015946 Eye irritation Diseases 0.000 description 2
- GLZPCOQZEFWAFX-UHFFFAOYSA-N Geraniol Chemical compound CC(C)=CCCC(C)=CCO GLZPCOQZEFWAFX-UHFFFAOYSA-N 0.000 description 2
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- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- 241000511976 Hoya Species 0.000 description 2
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- 239000003945 anionic surfactant Substances 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 229960003237 betaine Drugs 0.000 description 2
- 239000004359 castor oil Substances 0.000 description 2
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- 229960003260 chlorhexidine Drugs 0.000 description 2
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- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 2
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- FDCJDKXCCYFOCV-UHFFFAOYSA-N 1-hexadecoxyhexadecane Chemical compound CCCCCCCCCCCCCCCCOCCCCCCCCCCCCCCCC FDCJDKXCCYFOCV-UHFFFAOYSA-N 0.000 description 1
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- FZWBNHMXJMCXLU-UHFFFAOYSA-N 2,3,4,5-tetrahydroxy-6-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal Chemical compound OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OCC(O)C(O)C(O)C(O)C=O)O1 FZWBNHMXJMCXLU-UHFFFAOYSA-N 0.000 description 1
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 description 1
- XPALGXXLALUMLE-UHFFFAOYSA-N 2-(dimethylamino)tetradecanoic acid Chemical compound CCCCCCCCCCCCC(N(C)C)C(O)=O XPALGXXLALUMLE-UHFFFAOYSA-N 0.000 description 1
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Priority Applications (1)
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|---|---|---|---|
| JP2003071181A JP4135905B2 (ja) | 2003-03-17 | 2003-03-17 | 清涼化剤を含有するコンタクトレンズ用点眼剤 |
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| Application Number | Priority Date | Filing Date | Title |
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| JP2003071181A JP4135905B2 (ja) | 2003-03-17 | 2003-03-17 | 清涼化剤を含有するコンタクトレンズ用点眼剤 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP34903797A Division JP4274593B2 (ja) | 1997-12-18 | 1997-12-18 | 清涼化剤を含有するコンタクトレンズ用点眼剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| JP2007145209A Division JP5477798B2 (ja) | 2007-05-31 | 2007-05-31 | 清涼化剤を含有するコンタクトレンズ用点眼剤 |
Publications (3)
| Publication Number | Publication Date |
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| JP2003279906A JP2003279906A (ja) | 2003-10-02 |
| JP2003279906A5 JP2003279906A5 (https=) | 2005-03-03 |
| JP4135905B2 true JP4135905B2 (ja) | 2008-08-20 |
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| JP2003071181A Expired - Lifetime JP4135905B2 (ja) | 2003-03-17 | 2003-03-17 | 清涼化剤を含有するコンタクトレンズ用点眼剤 |
Country Status (1)
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| JP (1) | JP4135905B2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4718160B2 (ja) * | 2003-11-12 | 2011-07-06 | ロート製薬株式会社 | 眼科用組成物 |
| JP5401113B2 (ja) * | 2008-02-07 | 2014-01-29 | ロート製薬株式会社 | メントール類を含有する亜塩素酸類化合物含有水性組成物 |
| JP2013032393A (ja) * | 2012-11-09 | 2013-02-14 | Rohto Pharmaceutical Co Ltd | 清涼化剤を含有するコンタクトレンズ用点眼剤 |
| TWI607768B (zh) * | 2017-03-31 | 2017-12-11 | 晶碩光學股份有限公司 | 隱形眼鏡用組成物及隱形眼鏡的保養方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2822058B2 (ja) * | 1989-05-29 | 1998-11-05 | ゼリア新薬工業株式会社 | 安定な点眼剤 |
| JPH0816042B2 (ja) * | 1989-08-08 | 1996-02-21 | ロート製薬株式会社 | コンタクトレンズ用液剤 |
| JP3689123B2 (ja) * | 1993-10-22 | 2005-08-31 | ライオン株式会社 | ビタミンａ類可溶化水性点眼剤 |
| JP3597239B2 (ja) * | 1994-03-31 | 2004-12-02 | ライオン株式会社 | 安定な点眼剤 |
| WO1997028827A1 (fr) * | 1996-02-07 | 1997-08-14 | Rohto Pharmaceutical Co., Ltd. | Composition ophtalmique possedant une viscosite adaptee |
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2003
- 2003-03-17 JP JP2003071181A patent/JP4135905B2/ja not_active Expired - Lifetime
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| JP2003279906A (ja) | 2003-10-02 |
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