JP4130535B2 - 脊椎の隣接する椎骨の間に移植するための整形外科インプラント - Google Patents

脊椎の隣接する椎骨の間に移植するための整形外科インプラント Download PDF

Info

Publication number
JP4130535B2
JP4130535B2 JP2001056570A JP2001056570A JP4130535B2 JP 4130535 B2 JP4130535 B2 JP 4130535B2 JP 2001056570 A JP2001056570 A JP 2001056570A JP 2001056570 A JP2001056570 A JP 2001056570A JP 4130535 B2 JP4130535 B2 JP 4130535B2
Authority
JP
Japan
Prior art keywords
bag
polymer
adjacent vertebrae
implantation
spine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2001056570A
Other languages
English (en)
Other versions
JP2001276099A5 (ja
JP2001276099A (ja
Inventor
シー．スタルカップ グレゴリー
ジェイ．ロジアー アントニー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of JP2001276099A publication Critical patent/JP2001276099A/ja
Publication of JP2001276099A5 publication Critical patent/JP2001276099A5/ja
Application granted granted Critical
Publication of JP4130535B2 publication Critical patent/JP4130535B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7097—Stabilisers comprising fluid filler in an implant, e.g. balloon; devices for inserting or filling such implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7097—Stabilisers comprising fluid filler in an implant, e.g. balloon; devices for inserting or filling such implants
    • A61B17/7098—Stabilisers comprising fluid filler in an implant, e.g. balloon; devices for inserting or filling such implants wherein the implant is permeable or has openings, e.g. fenestrated screw
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/441—Joints for the spine, e.g. vertebrae, spinal discs made of inflatable pockets or chambers filled with fluid, e.g. with hydrogel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • A61F2/4465—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages having a circular or kidney shaped cross-section substantially perpendicular to the axis of the spine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4601—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for introducing bone substitute, for implanting bone graft implants or for compacting them in the bone cavity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2/4611—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of spinal prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/3209—Incision instruments
    • A61B17/3211—Surgical scalpels, knives; Accessories therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/70—Spinal positioners or stabilisers ; Bone stabilisers comprising fluid filler in an implant
    • A61B17/7094—Solid vertebral fillers; devices for inserting such fillers
    • A61B17/7095—Solid vertebral fillers; devices for inserting such fillers the filler comprising unlinked macroscopic particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30721—Accessories
    • A61F2/30744—End caps, e.g. for closing an endoprosthetic cavity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442—Intervertebral or spinal discs, e.g. resilient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006—Properties of materials and coating materials
    • A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108—Shapes
    • A61F2002/3011—Cross-sections or two-dimensional shapes
    • A61F2002/30112—Rounded shapes, e.g. with rounded corners
    • A61F2002/30133—Rounded shapes, e.g. with rounded corners kidney-shaped or bean-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108—Shapes
    • A61F2002/30199—Three-dimensional shapes
    • A61F2002/302—Three-dimensional shapes toroidal, e.g. rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30581—Special structural features of bone or joint prostheses not otherwise provided for having a pocket filled with fluid, e.g. liquid
    • A61F2002/30583—Special structural features of bone or joint prostheses not otherwise provided for having a pocket filled with fluid, e.g. liquid filled with hardenable fluid, e.g. curable in-situ
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30593—Special structural features of bone or joint prostheses not otherwise provided for hollow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2002/4625—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use
    • A61F2002/4627—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use with linear motion along or rotating motion about the instrument axis or the implantation direction, e.g. telescopic, along a guiding rod, screwing inside the instrument
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2002/4635—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor using minimally invasive surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2002/465—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor using heating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0085—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof hardenable in situ, e.g. epoxy resins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004—Rounded shapes, e.g. with rounded corners
    • A61F2230/0015—Kidney-shaped, e.g. bean-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0065—Three-dimensional shapes toroidal, e.g. ring-shaped, doughnut-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00353—Bone cement, e.g. polymethylmethacrylate or PMMA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs

Landscapes

  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Prostheses (AREA)
  • Surgical Instruments (AREA)
  • Materials For Medical Uses (AREA)

Description

【０００１】
【発明の属する技術分野】
本発明は、整形外科インプラントすなわち整形外科移植装置に関し、より詳細には、脊椎固定（術）装置に関する。
【０００２】
【従来の技術】
脊椎固定術は、通常、２つの隣接する椎骨の間の椎間板を除去してそれら椎骨の間にケージを設置することによって、２つの隣接する椎骨の間を固定することを必要とする。患者は前側及び後側（胃及び背中）の両方を切開され、椎間板が２つの隣接する椎骨の間から除去されることがある。椎間板には核部（髄核）の周囲を取り囲む輪部（線維輪）が含まれている。輪部を引き裂いたり、切開したり、若しくは椎骨の間から除去したりして、さらに、より柔軟な核部を除去する。椎骨の間の椎間板が除去された場所にケージを配置し、骨粒を含んだ骨グラフト（骨移植体）をケージ内に詰め込んで隣接する椎骨の間の終板の間に延在させる。さらに、ネジがそれぞれのロッドに取り付られそれぞれの椎骨内に延びた状態で、ロッドを脊椎の後側に配置してもよい。
【０００３】
【発明が解決しようとする課題】
本発明の目的は、最小侵襲の外科手術手順で脊椎の隣接する椎骨の間に移植され得る整形外科インプラントを提供することである。
【０００４】
【課題を解決するための手段】
本発明は、椎間板の輪部によって周囲を取り囲まれている空洞内に配置され且つ中央空洞部を含んでいるバッグ（すなわち、袋）を備えた整形外科インプラントを提供する。バッグはポリマを充填され、バッグによって形成される中央空洞部は骨粒及びポリマ基質を充填される。
【０００５】
本発明は、１つの形態で、概略環状のバッグとこのバッグ内の硬化したポリマとを備えている脊椎の隣接する椎骨の間に移植するための整形外科インプラントからなる。
本発明は、他の形態で、隣接する椎骨の間の椎間板の輪部にアクセス孔を形成するステップと、輪部により周囲を取り囲まれている空洞を形成するために椎間板内の核部を除去するステップと、空洞内に概略環状のバッグを配置するステップと、バッグにポリマを充填するステップと、環状のバッグにより周囲を取り囲まれている空洞に骨粒を注入するステップと、ポリマを硬化させるステップと、を含む脊椎の隣接する椎骨を固定する方法からなる。
【０００６】
本発明の利点は、脊椎を取り囲む靱帯及び腱が適正な張力をかけられ得ることである。
他の利点は、患者が手術後すぐにインプラントに荷重を加え始めることができることである。
さらに別の利点は、インプラントを単一の後部切開部位から移植することもできれば、後部及び／又は前部切開部位から移植することもできることである。
【０００７】
【発明の実施の形態】
添付の図面に関連する本発明の実施態様の以下の説明を参照することにより、本発明の上述した特徴及び利点並びに他の特徴及び利点、それらを実施する態様がさらに明らかとなり、本発明がより深く理解されよう。
複数の図面を通して対応する参照符号は対応する部分を指している。本願に提示されている具体例は本発明の好ましい一実施態様を一形態で示しているのであり、係る具体例が如何なる形でも本発明の範囲を制限するものとして解釈されるべきではない。
【０００８】
以下で、図面を参照して、本発明の脊椎の隣接する椎骨を固定するための方法の実施態様を説明する。脊椎には複数の隣接する椎骨１０が含まれており、隣接する椎骨１０の各対は椎間板１２により分離されている。椎間板１２は幾つかの理由により損傷を受けた状態になり、したがって、隣接する椎骨の固定を必要とすることがある。
【０００９】
図１は患者の脊椎と平行な方向に見たときの脊髄の部分断面図を示している。椎間板１２は、隣接する椎骨１０の間での固定を必要とする程度まで損傷を受けているものとする。図２を参照すると、各椎骨１０は長手方向の各端部に逆側を向いている終板２４を含んでいる。各椎間板１２は一対の隣接する椎骨の間に介在し、さらに核部（髄核）２８の周囲を取り囲んでいる輪部（線維輪）２６を含んでいる。
【００１０】
メス１８や他の適宜の切開器具を用いて患者の背中１６に切開部１４を形成する。切開部１４は適宜の機器２０を用いて開いた状態に保持されてもよい。椎間板１２に対して概略示されているような角度で切開部１４を形成し、それによって、脊髄が位置している領域２２を回避する。切開部１４が形成された後に、ドリルの刃先やメスのような公知の方法によって、選択された椎間板１２の輪部２６にアクセス孔３０を形成する。切開部１４を患者の背中１６に形成することから、通常、アクセス孔３０を椎間板１２の後方側に形成する。
【００１１】
アクセス孔３０の形成後、核部２８を椎間板１２内から排出させる（図３）。核部２８を除去するために、真空管３４又は同種のものを使用することができる。核部２８の除去は、輪部２６によって周囲を取り囲まれている空洞４２を椎間板１２内に形成させる。核部２８の排出後に、空洞４２及び切開部１４から真空管３４を除去する。
【００１２】
次に、弛緩状態のときに概略環状形状を有している柔軟なバッグ４４を空洞４２内に挿入する（図４）。より詳細には、バッグ４４を折り畳んで、事前装填管４６内に挿入する。事前装填管４６は輪部２６に形成されているアクセス孔３０の内径よりも僅かに小さい外径を有する。事前装填管４６の端部４８がアクセス孔３０を貫通して空洞４２内に延びるように、内部にバッグ４４が装填されている事前装填管４６を切開部１４及びアクセス孔３０に挿入する。次に、矢印５０によって示されているように、バッグ４４を事前装填管４６から空洞４２内へ滑動させる。事前装填管４６の内径よりも僅かに小さい外径を有し事前装填管４６内に配置されているプランジャ（不図示）を利用することによる方法のような適宜の方法で、バッグ４４を事前装填管４６から駆出することが可能である。
【００１３】
空洞４２内に設置されたときに空洞４２の周囲を概略充塞するような大きさ及び形状を有しているバッグ４４が選択される（図５）。第１の充填ホース５２及び第２の充填ホース５４の各々がバッグ４４に取り付けられる（図５〜図１１）。第１のホース５２は、バッグ４４を貫通して延びており、バッグ４４によって周囲を取り囲まれている空洞４２の部分で終端している（図６）。他方、第２の充填ホース５４は、バッグ４４内に延びており、バッグ４４内で終端している。矢印５６によって示されているように、第２の充填ホース５４を通してバッグ４４内に高強度ポリマを注入する。バッグ４４のこの第１充填段階の際には、ポリマ５８を注入して、バッグ４４を膨張又は変形させることなく、予め定められた第１の量までバッグ４４に概略充填する。示されている実施態様では、バッグ４４は多孔性のものであり、ポリマ５８は生体吸収性且つ硬化性のポリマーの形態のものであり、その一部がバッグ４４を透過する。ポリマ５８は例えばポリメチルメタクリレートなどである。硬化は、熱エネルギや光エネルギやＸ線エネルギのようなエネルギの付加又は化学的触媒の添加によって行われ得る。図６に示されているバッグ４４の第１充填段階の際には、好ましくは、ポリマ５８は未硬化状態を維持している。
【００１４】
次に、矢印６２によって示されているように、第１の充填ホース５２を通してバッグ４４によって周囲を取り囲まれている空洞４２の部分内に骨粒６０の形態の骨グラフト（骨移植体）を注入する。骨代用材料を使用することもできることは了解されよう。示されている実施態様では、骨粒６０は合成骨代用物のような液体内を浮遊した状態になっている。
【００１５】
バッグ４４によって周囲を取り囲まれている空洞４２の部分が図７に示されているように概略充満されるまで、第１の充填ホース５２を通して空洞４２内に骨粒及び懸濁液が注入される。その後、骨粒６０を空洞４２内に保持して、追加でポリマ５８をバッグ４４内に注入する。予め定められた第２の量までバッグ４４内にポリマ５８を注入して、バッグ４４を膨張させる。バッグ４４は（椎間板１２に対して）軸線方向に膨張して、終板２４に接触する。さらに、バッグ４４は半径方向内向き方向に膨張して、空洞４２内において骨粒６０を半径方向に圧縮すると共に軸線方向に膨張させる。したがって、椎骨１０を取り囲む靱帯及び腱に対して、その間で骨粒６０を軸線方向に膨張させることにより、張力を再度かけることが可能となる。さらに、骨粒６０及びバッグ４４が接触する領域の概略全てが荷重支持部材を形成することから、固定領域は大きな接触面積を備えることとなる。
【００１６】
比較的早い方法で、バッグ４４内のポリマ化合物又はポリマ混合物５８並びに骨粒６０を取り囲みそれを支持しているポリマを荷重支持状態へ硬化させることもできる。例えば、ポリマ化合物又はポリマ混合物をＸ線エネルギ又は化学的触媒で硬化させることができる。したがって、最小限の侵襲（minimal evasive）であることに加えて、患者は、整形外科インプラント８内でポリマを硬化させた後に、着座、起立などを通して迅速に脊椎に荷重を付加することができる。第１の充填ホース５２及び第２の充填ホース５４は図９に示されているように整形外科インプラント８から切断され、切開部１４が適宜の閉鎖技術を用いて閉鎖される。
【００１７】
上記の説明から、本発明が最小侵襲の外科手術手順で椎間板１２内に容易に移植され得る整形外科インプラント８を提供することが分かるであろう。隣接する椎骨１０の間でバッグ内のポリマの硬化が急速に起こり、椎骨の間に荷重の伝達のための大きな表面積と骨の再成長のための安定した構造を提供する。
【００１８】
本発明が好ましい構造を有するものとして説明されたが、本発明を本開示内容の精神及び範囲内でさらに改変することができる。したがって、本願は本発明の総合的な原理を用いて本発明の任意の変化形態、用途、適用形態を網羅することを意図するものである。さらに、本願は、本発明が属する当該技術において公知のもの又は慣習的な実施の範囲となるような特許請求の範囲の限定内に入る本開示内容からの逸脱事項を網羅することを意図している。
【図面の簡単な説明】
【図１】椎骨及び椎間板の部分断面図であり、椎骨及び椎間板に対して形成された切開部の向き及び大きさを示している。
【図２】椎間板内の核部の排出を示している斜視図である。
【図３】椎間板内の環状バッグの設置を示している斜視図である。
【図４】椎間板内に設置された後の弛緩状態のバッグの斜視図である。
【図５】予め定められた第１の量までポリマを充填した際のバッグの側断面図である。
【図６】バッグによって周囲を取り囲まれた空洞内に注入された骨粒及びポリマ基質を示している側断面図である。
【図７】骨粒を注入した後に予め定められた第２の量まで充填されたバッグを示している側断面図である。
【図８】整形外科インプラントが椎間板内に移植され切開部が閉鎖された状態になっている部分断面図である。
【図９】図４〜図９に示されているバッグの斜視図である。
【図１０】図４〜図１０に示されているバッグの側断面図である。
【符号の説明】
１０…椎骨
１２…椎間板
２６…輪部
２８…核部
３０…アクセス孔
４４…バッグ
５８…ポリマ
６０…骨粒

Claims (5)

  1. 概略環状のバッグと、
    前記バッグ内に充填されたポリマと、
    前記バックを貫通して延びており、前記バックによって周囲を取り囲まれている空洞の部分で終端している第１の充填管と、
    前記ポリマを前記バッグに注入するために前記バッグと接続されている第２の充填管とを備える、脊椎の隣接する椎骨の間に移植するための整形外科インプラント。
  2. 前記ポリマが硬化可能なポリマからなる、請求項１に記載の脊椎の隣接する椎骨の間に移植するための整形外科インプラント。
  3. 前記ポリマが、熱エネルギ、光エネルギ、Ｘ線エネルギ及び化学的触媒のうちの１つにより硬化可能である、請求項２に記載の脊椎の隣接する椎骨の間に移植するための整形外科インプラント。
  4. 前記ポリマがポリメチルメタクリレートからなる、請求項３に記載の脊椎の隣接する椎骨の間に移植するための整形外科インプラント。
  5. 前記バッグが多孔性バッグからなり、前記ポリマの一部が前記バッグを透過することを許容する、請求項１に記載の脊椎の隣接する椎骨の間に移植するための整形外科インプラント。
JP2001056570A 2000-03-07 2001-03-01 脊椎の隣接する椎骨の間に移植するための整形外科インプラント Expired - Fee Related JP4130535B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/520893 2000-03-07
US09/520,893 US6332894B1 (en) 2000-03-07 2000-03-07 Polymer filled spinal fusion cage

Publications (3)

Publication Number Publication Date
JP2001276099A JP2001276099A (ja) 2001-10-09
JP2001276099A5 JP2001276099A5 (ja) 2005-07-28
JP4130535B2 true JP4130535B2 (ja) 2008-08-06

Family

ID=24074481

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001056570A Expired - Fee Related JP4130535B2 (ja) 2000-03-07 2001-03-01 脊椎の隣接する椎骨の間に移植するための整形外科インプラント

Country Status (7)

Country Link
US (1) US6332894B1 (ja)
EP (1) EP1132061B1 (ja)
JP (1) JP4130535B2 (ja)
AU (1) AU772702B2 (ja)
CA (1) CA2337593C (ja)
DE (1) DE60104918T2 (ja)
ES (1) ES2227068T3 (ja)

Families Citing this family (265)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002505592A (ja) 1996-11-15 2002-02-19 アドバンスト バイオ サーフェイシズ，インコーポレイティド 生体内原位置で組織を修復するのに用いる生体用材料システム
US8083745B2 (en) 2001-05-25 2011-12-27 Conformis, Inc. Surgical tools for arthroplasty
US7468075B2 (en) 2001-05-25 2008-12-23 Conformis, Inc. Methods and compositions for articular repair
US7618451B2 (en) 2001-05-25 2009-11-17 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools facilitating increased accuracy, speed and simplicity in performing total and partial joint arthroplasty
US7534263B2 (en) 2001-05-25 2009-05-19 Conformis, Inc. Surgical tools facilitating increased accuracy, speed and simplicity in performing joint arthroplasty
US7184814B2 (en) 1998-09-14 2007-02-27 The Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and assessing cartilage loss
JP2002532126A (ja) 1998-09-14 2002-10-02 スタンフォード ユニバーシティ 関節状態の評価及び損傷防止装置
US7239908B1 (en) 1998-09-14 2007-07-03 The Board Of Trustees Of The Leland Stanford Junior University Assessing the condition of a joint and devising treatment
AU3187000A (en) 1999-03-07 2000-09-28 Discure Ltd. Method and apparatus for computerized surgery
US7951201B2 (en) 1999-10-20 2011-05-31 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7052516B2 (en) 1999-10-20 2006-05-30 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and deformable spinal disc annulus stent
US6592625B2 (en) 1999-10-20 2003-07-15 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and spinal disc annulus stent
US7004970B2 (en) 1999-10-20 2006-02-28 Anulex Technologies, Inc. Methods and devices for spinal disc annulus reconstruction and repair
US7615076B2 (en) 1999-10-20 2009-11-10 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US8632590B2 (en) 1999-10-20 2014-01-21 Anulex Technologies, Inc. Apparatus and methods for the treatment of the intervertebral disc
US8128698B2 (en) 1999-10-20 2012-03-06 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7935147B2 (en) 1999-10-20 2011-05-03 Anulex Technologies, Inc. Method and apparatus for enhanced delivery of treatment device to the intervertebral disc annulus
US6740093B2 (en) 2000-02-28 2004-05-25 Stephen Hochschuler Method and apparatus for treating a vertebral body
US6805695B2 (en) 2000-04-04 2004-10-19 Spinalabs, Llc Devices and methods for annular repair of intervertebral discs
SE520688C2 (sv) 2000-04-11 2003-08-12 Bone Support Ab Ett injicerbart ersättningsmaterial för benmineral
US6964667B2 (en) 2000-06-23 2005-11-15 Sdgi Holdings, Inc. Formed in place fixation system with thermal acceleration
US6875212B2 (en) 2000-06-23 2005-04-05 Vertelink Corporation Curable media for implantable medical device
US6749614B2 (en) 2000-06-23 2004-06-15 Vertelink Corporation Formable orthopedic fixation system with cross linking
US6899713B2 (en) 2000-06-23 2005-05-31 Vertelink Corporation Formable orthopedic fixation system
AU2001225881A1 (en) 2000-06-23 2002-01-08 University Of Southern California Percutaneous vertebral fusion system
US20020026244A1 (en) * 2000-08-30 2002-02-28 Trieu Hai H. Intervertebral disc nucleus implants and methods
US7204851B2 (en) 2000-08-30 2007-04-17 Sdgi Holdings, Inc. Method and apparatus for delivering an intervertebral disc implant
US7503936B2 (en) * 2000-08-30 2009-03-17 Warsaw Orthopedic, Inc. Methods for forming and retaining intervertebral disc implants
AU9088801A (en) 2000-09-14 2002-03-26 Univ Leland Stanford Junior Assessing the condition of a joint and devising treatment
ES2358498T3 (es) * 2000-10-24 2011-05-11 Cryolife, Inc. Relleno bioprostético y métodos, particularmente para la formación in situ de bioprótesis de discos intervertebrales.
US7226615B2 (en) * 2000-11-07 2007-06-05 Cryolife, Inc. Expandable foam-like biomaterials and methods
NZ525999A (en) * 2000-12-15 2006-05-26 Spineology Inc Annulus-reinforcing band
US6652585B2 (en) * 2001-02-28 2003-11-25 Sdgi Holdings, Inc. Flexible spine stabilization system
US7229441B2 (en) * 2001-02-28 2007-06-12 Warsaw Orthopedic, Inc. Flexible systems for spinal stabilization and fixation
US6827743B2 (en) * 2001-02-28 2004-12-07 Sdgi Holdings, Inc. Woven orthopedic implants
US7344539B2 (en) * 2001-03-30 2008-03-18 Depuy Acromed, Inc. Intervertebral connection system
US6632235B2 (en) 2001-04-19 2003-10-14 Synthes (U.S.A.) Inflatable device and method for reducing fractures in bone and in treating the spine
US8951260B2 (en) 2001-05-25 2015-02-10 Conformis, Inc. Surgical cutting guide
US8439926B2 (en) 2001-05-25 2013-05-14 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools
CN100502808C (zh) 2001-05-25 2009-06-24 肯弗默斯股份有限公司 用于关节表面再造的组合物
FR2829689B1 (fr) * 2001-09-14 2004-06-25 Frederic Fortin Prothese de nucleus et son dispositif d'insertion ainsi que son procede de mise en place
AU2002336694A1 (en) * 2001-11-01 2003-05-12 Lawrence M. Boyd Devices and methods for the restoration of a spinal disc
WO2003037165A2 (en) * 2001-11-01 2003-05-08 Boyd Lawrence M System and method for the pretreatment of the endplates of an intervertebral disc
DE10154163A1 (de) * 2001-11-03 2003-05-22 Advanced Med Tech Vorrichtung zum Aufrichten und Stabilisieren der Wirbelsäule
CA2468908C (en) * 2001-12-05 2009-03-31 Mathys Medizinaltechnik Ag Intervertebral disk prosthesis or nucleus replacement prosthesis
SE522098C2 (sv) 2001-12-20 2004-01-13 Bone Support Ab Ett nytt benmineralsubstitut
US6793678B2 (en) 2002-06-27 2004-09-21 Depuy Acromed, Inc. Prosthetic intervertebral motion disc having dampening
BR0313499A (pt) 2002-08-15 2005-07-05 David Gerber Disco intervertebral
US7682392B2 (en) 2002-10-30 2010-03-23 Depuy Spine, Inc. Regenerative implants for stabilizing the spine and devices for attachment of said implants
EP1562524A4 (en) * 2002-11-05 2010-12-22 Spineology Inc SEMIBIOLOGICAL BRAKE REPLACEMENT SYSTEM
US6733533B1 (en) * 2002-11-19 2004-05-11 Zimmer Technology, Inc. Artificial spinal disc
AU2003295717B2 (en) * 2002-11-21 2009-10-01 Hai H. Trieu Systems and techniques for interbody spinal stabilization with expandable devices
WO2004047689A1 (en) * 2002-11-21 2004-06-10 Sdgi Holdings, Inc. Systems and techniques for intravertebral spinal stablization with expandable devices
BRPI0407142A (pt) * 2003-02-14 2006-01-10 Depuy Spine Inc Dispositivo de fusão intervertebral formado in situ
SE0300620D0 (sv) 2003-03-05 2003-03-05 Bone Support Ab A new bone substitute composition
US20040193270A1 (en) * 2003-03-31 2004-09-30 Depuyacromed, Inc. Implantable bone graft
US20040220672A1 (en) * 2003-05-03 2004-11-04 Shadduck John H. Orthopedic implants, methods of use and methods of fabrication
CN100344263C (zh) * 2003-06-02 2007-10-24 英属维京群岛商冠亚股份有限公司 一种脊椎填充装置
CN100430030C (zh) * 2003-06-20 2008-11-05 林冠谷 一种可抽解动物组织填充装置
US20040267367A1 (en) 2003-06-30 2004-12-30 Depuy Acromed, Inc Intervertebral implant with conformable endplate
PT1495730E (pt) * 2003-07-08 2007-02-28 A Spine Holding Group Corp Dispositivo de implantação para tratar uma coluna vertebral deformada ou doente
US6958077B2 (en) * 2003-07-29 2005-10-25 Loubert Suddaby Inflatable nuclear prosthesis
EP2193812A1 (en) * 2003-09-19 2010-06-09 Broockeville Corporation N.V. Use of a curable elastomer-precursor for a medical treatment
US7632294B2 (en) 2003-09-29 2009-12-15 Promethean Surgical Devices, Llc Devices and methods for spine repair
US7655010B2 (en) * 2003-09-30 2010-02-02 Depuy Spine, Inc. Vertebral fusion device and method for using same
US8052613B2 (en) 2003-10-23 2011-11-08 Trans1 Inc. Spinal nucleus extraction tool
SE0302983D0 (sv) * 2003-11-11 2003-11-11 Bone Support Ab Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed
US7837732B2 (en) 2003-11-20 2010-11-23 Warsaw Orthopedic, Inc. Intervertebral body fusion cage with keels and implantation methods
US7670377B2 (en) 2003-11-21 2010-03-02 Kyphon Sarl Laterally insertable artifical vertebral disk replacement implant with curved spacer
US7217293B2 (en) * 2003-11-21 2007-05-15 Warsaw Orthopedic, Inc. Expandable spinal implant
US20050209603A1 (en) * 2003-12-02 2005-09-22 St. Francis Medical Technologies, Inc. Method for remediation of intervertebral disks
ES2403357T3 (es) 2003-12-11 2013-05-17 Isto Technologies Inc. Sistema de cartílago particulado
US7789912B2 (en) 2004-01-08 2010-09-07 Spine Wave, Inc. Apparatus and method for injecting fluent material at a distracted tissue site
DE602005023583D1 (de) 2004-02-09 2010-10-28 Depuy Spine Inc Systeme für die wirbelsäulen-chirurgie
US8636802B2 (en) 2004-03-06 2014-01-28 DePuy Synthes Products, LLC Dynamized interspinal implant
US8945223B2 (en) * 2004-03-12 2015-02-03 Warsaw Orthopedic, Inc. In-situ formable nucleus pulposus implant with water absorption and swelling capability
US20080132899A1 (en) * 2004-05-17 2008-06-05 Shadduck John H Composite implant and method for treating bone abnormalities
US20060095138A1 (en) 2004-06-09 2006-05-04 Csaba Truckai Composites and methods for treating bone
US20050278027A1 (en) * 2004-06-11 2005-12-15 Hyde Edward R Jr Annulus fibrosus stent
SE527528C2 (sv) 2004-06-22 2006-04-04 Bone Support Ab Anordning för framställning av härdbar massa samt användning av anordningen
US7837733B2 (en) 2004-06-29 2010-11-23 Spine Wave, Inc. Percutaneous methods for injecting a curable biomaterial into an intervertebral space
US7799081B2 (en) 2004-09-14 2010-09-21 Aeolin, Llc System and method for spinal fusion
US7678116B2 (en) 2004-12-06 2010-03-16 Dfine, Inc. Bone treatment systems and methods
US7559932B2 (en) 2004-12-06 2009-07-14 Dfine, Inc. Bone treatment systems and methods
US7682378B2 (en) 2004-11-10 2010-03-23 Dfine, Inc. Bone treatment systems and methods for introducing an abrading structure to abrade bone
US7799078B2 (en) * 2004-11-12 2010-09-21 Warsaw Orthopedic, Inc. Implantable vertebral lift
US8562607B2 (en) * 2004-11-19 2013-10-22 Dfine, Inc. Bone treatment systems and methods
US7717918B2 (en) 2004-12-06 2010-05-18 Dfine, Inc. Bone treatment systems and methods
US7722620B2 (en) 2004-12-06 2010-05-25 Dfine, Inc. Bone treatment systems and methods
US8070753B2 (en) 2004-12-06 2011-12-06 Dfine, Inc. Bone treatment systems and methods
US7655046B2 (en) * 2005-01-20 2010-02-02 Warsaw Orthopedic, Inc. Expandable spinal fusion cage and associated instrumentation
US8702718B2 (en) 2005-04-29 2014-04-22 Jmea Corporation Implantation system for tissue repair
US7608108B2 (en) 2005-04-29 2009-10-27 Jmea Corporation Tissue repair system
US7632313B2 (en) 2005-04-29 2009-12-15 Jmea Corporation Disc repair system
US20060253198A1 (en) * 2005-05-03 2006-11-09 Disc Dynamics, Inc. Multi-lumen mold for intervertebral prosthesis and method of using same
US7955339B2 (en) * 2005-05-24 2011-06-07 Kyphon Sarl Low-compliance expandable medical device
US8092528B2 (en) 2005-05-27 2012-01-10 Depuy Spine, Inc. Intervertebral ligament having a helical bone fastener
WO2006130796A2 (en) 2005-06-02 2006-12-07 Zimmer Spine, Inc. Interbody fusion ring and method of using the same
US20070162135A1 (en) * 2005-06-15 2007-07-12 Jerome Segal Mechanical apparatus and method for artificial disc replacement
US7442210B2 (en) 2005-06-15 2008-10-28 Jerome Segal Mechanical apparatus and method for artificial disc replacement
US7547319B2 (en) * 2005-06-15 2009-06-16 Ouroboros Medical Mechanical apparatus and method for artificial disc replacement
US8021426B2 (en) * 2005-06-15 2011-09-20 Ouroboros Medical, Inc. Mechanical apparatus and method for artificial disc replacement
US7601172B2 (en) 2005-06-15 2009-10-13 Ouroboros Medical, Inc. Mechanical apparatus and method for artificial disc replacement
US20070055379A1 (en) * 2005-08-03 2007-03-08 Stone Corbett W Annular access devices
US7618457B2 (en) * 2005-08-10 2009-11-17 Zimmer Spine, Inc. Devices and methods for disc nucleus replacement
US8777479B2 (en) 2008-10-13 2014-07-15 Dfine, Inc. System for use in bone cement preparation and delivery
US9066769B2 (en) 2005-08-22 2015-06-30 Dfine, Inc. Bone treatment systems and methods
US8540723B2 (en) 2009-04-14 2013-09-24 Dfine, Inc. Medical system and method of use
JP5292533B2 (ja) 2005-08-26 2013-09-18 ジンマー・インコーポレイテッド インプラントおよび関節疾患の治療、置換および治療方法
US9028550B2 (en) 2005-09-26 2015-05-12 Coalign Innovations, Inc. Selectively expanding spine cage with enhanced bone graft infusion
US20070093906A1 (en) * 2005-10-26 2007-04-26 Zimmer Spine, Inc. Nucleus implant and method
US8197545B2 (en) 2005-10-27 2012-06-12 Depuy Spine, Inc. Nucleus augmentation delivery device and technique
US20070162132A1 (en) 2005-12-23 2007-07-12 Dominique Messerli Flexible elongated chain implant and method of supporting body tissue with same
US7645301B2 (en) * 2006-01-13 2010-01-12 Zimmer Spine, Inc. Devices and methods for disc replacement
US7799079B2 (en) * 2006-01-18 2010-09-21 Zimmer Spine, Inc. Vertebral fusion device and method
US20070179614A1 (en) * 2006-01-30 2007-08-02 Sdgi Holdings, Inc. Intervertebral prosthetic disc and method of installing same
EP1981409B1 (en) 2006-02-06 2017-01-11 ConforMIS, Inc. Patient selectable joint arthroplasty devices and surgical tools
US8623026B2 (en) 2006-02-06 2014-01-07 Conformis, Inc. Patient selectable joint arthroplasty devices and surgical tools incorporating anatomical relief
WO2007122608A2 (en) 2006-04-20 2007-11-01 Depuy Spine, Inc. Instrumentation kit for delivering viscous bone filler material
US7806900B2 (en) 2006-04-26 2010-10-05 Illuminoss Medical, Inc. Apparatus and methods for delivery of reinforcing materials to bone
US8348978B2 (en) 2006-04-28 2013-01-08 Warsaw Orthopedic, Inc. Interosteotic implant
US8105357B2 (en) 2006-04-28 2012-01-31 Warsaw Orthopedic, Inc. Interspinous process brace
US8252031B2 (en) 2006-04-28 2012-08-28 Warsaw Orthopedic, Inc. Molding device for an expandable interspinous process implant
US8048118B2 (en) 2006-04-28 2011-11-01 Warsaw Orthopedic, Inc. Adjustable interspinous process brace
US7846185B2 (en) 2006-04-28 2010-12-07 Warsaw Orthopedic, Inc. Expandable interspinous process implant and method of installing same
US20070276491A1 (en) * 2006-05-24 2007-11-29 Disc Dynamics, Inc. Mold assembly for intervertebral prosthesis
US8092536B2 (en) 2006-05-24 2012-01-10 Disc Dynamics, Inc. Retention structure for in situ formation of an intervertebral prosthesis
US8226722B2 (en) * 2006-06-08 2012-07-24 Francis Pflum Sac for use in spinal surgery
US10143560B2 (en) 2006-06-08 2018-12-04 Francis Pflum Sac for use in spinal surgery
US20080021457A1 (en) * 2006-07-05 2008-01-24 Warsaw Orthopedic Inc. Zygapophysial joint repair system
US20080058932A1 (en) * 2006-07-26 2008-03-06 Warsaw Orthopedic Inc. Rigidization-on-command orthopedic devices and methods
US8034110B2 (en) 2006-07-31 2011-10-11 Depuy Spine, Inc. Spinal fusion implant
US8506636B2 (en) 2006-09-08 2013-08-13 Theken Spine, Llc Offset radius lordosis
US9089437B2 (en) 2006-10-16 2015-07-28 Pioneer Surgical Technology, Inc. Fusion device, systems and methods thereof
CA2669129C (en) 2006-11-10 2014-09-16 Illuminoss Medical, Inc. Systems and methods for internal bone fixation
US7879041B2 (en) 2006-11-10 2011-02-01 Illuminoss Medical, Inc. Systems and methods for internal bone fixation
WO2008070863A2 (en) 2006-12-07 2008-06-12 Interventional Spine, Inc. Intervertebral implant
US8696679B2 (en) 2006-12-08 2014-04-15 Dfine, Inc. Bone treatment systems and methods
US20080154233A1 (en) * 2006-12-20 2008-06-26 Zimmer Orthobiologics, Inc. Apparatus for delivering a biocompatible material to a surgical site and method of using same
US8758407B2 (en) 2006-12-21 2014-06-24 Warsaw Orthopedic, Inc. Methods for positioning a load-bearing orthopedic implant device in vivo
US8480718B2 (en) 2006-12-21 2013-07-09 Warsaw Orthopedic, Inc. Curable orthopedic implant devices configured to be hardened after placement in vivo
US7771476B2 (en) * 2006-12-21 2010-08-10 Warsaw Orthopedic Inc. Curable orthopedic implant devices configured to harden after placement in vivo by application of a cure-initiating energy before insertion
US8663328B2 (en) 2006-12-21 2014-03-04 Warsaw Orthopedic, Inc. Methods for positioning a load-bearing component of an orthopedic implant device by inserting a malleable device that hardens in vivo
US7972382B2 (en) * 2006-12-26 2011-07-05 Warsaw Orthopedic, Inc. Minimally invasive spinal distraction devices and methods
US7643609B2 (en) * 2007-01-03 2010-01-05 Andrea Clay Secondary X-ray imaging technique for diagnosing a health condition
US20080249529A1 (en) * 2007-03-15 2008-10-09 Depuy Spine, Inc. Dual incision disc repair device and method
ES2438999T3 (es) 2007-04-03 2014-01-21 Dfine, Inc. Sistemas de tratamiento óseo
WO2008128075A1 (en) 2007-04-12 2008-10-23 Isto Technologies, Inc. Compositions and methods for tissue repair
WO2008137428A2 (en) 2007-04-30 2008-11-13 Dfine, Inc. Bone treatment systems and methods
US8273124B2 (en) 2007-05-17 2012-09-25 Depuy Spine, Inc. Self-distracting cage
US8900307B2 (en) 2007-06-26 2014-12-02 DePuy Synthes Products, LLC Highly lordosed fusion cage
US9597118B2 (en) 2007-07-20 2017-03-21 Dfine, Inc. Bone anchor apparatus and method
US20090088789A1 (en) * 2007-09-28 2009-04-02 O'neil Michael J Balloon With Shape Control For Spinal Procedures
US8043381B2 (en) * 2007-10-29 2011-10-25 Zimmer Spine, Inc. Minimally invasive interbody device and method
WO2009059090A1 (en) 2007-10-31 2009-05-07 Illuminoss Medical, Inc. Light source
US20090131867A1 (en) 2007-11-16 2009-05-21 Liu Y King Steerable vertebroplasty system with cavity creation element
US20090131886A1 (en) 2007-11-16 2009-05-21 Liu Y King Steerable vertebroplasty system
US9510885B2 (en) 2007-11-16 2016-12-06 Osseon Llc Steerable and curvable cavity creation system
US8403968B2 (en) 2007-12-26 2013-03-26 Illuminoss Medical, Inc. Apparatus and methods for repairing craniomaxillofacial bones using customized bone plates
US20090177206A1 (en) * 2008-01-08 2009-07-09 Zimmer Spine, Inc. Instruments, implants, and methods for fixation of vertebral compression fractures
EP2237748B1 (en) 2008-01-17 2012-09-05 Synthes GmbH An expandable intervertebral implant
US9445854B2 (en) 2008-02-01 2016-09-20 Dfine, Inc. Bone treatment systems and methods
JP5509098B2 (ja) 2008-02-28 2014-06-04 ディーエフアイエヌイー・インコーポレーテッド 骨治療システムおよび方法
US20090222097A1 (en) * 2008-02-28 2009-09-03 Warsaw Orthopedic, Inc. Nucleus implant and method of installing same
US20090240334A1 (en) * 2008-03-19 2009-09-24 Richelsoph Marc E Vertebral device for restoration of vertebral body height
AU2009228035A1 (en) * 2008-03-28 2009-10-01 Spineology Inc. Method and device for interspinous process fusion
CA2720580A1 (en) 2008-04-05 2009-10-08 Synthes Usa, Llc Expandable intervertebral implant
US9180416B2 (en) 2008-04-21 2015-11-10 Dfine, Inc. System for use in bone cement preparation and delivery
GB0813659D0 (en) 2008-07-25 2008-09-03 Smith & Nephew Fracture putty
US8163022B2 (en) 2008-10-14 2012-04-24 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
WO2010074704A1 (en) * 2008-12-22 2010-07-01 Synthes Usa, Llc Expandable vertebral body replacement device and method
CA2748751C (en) * 2008-12-31 2018-03-27 Spineology, Inc. System and method for performing percutaneous spinal interbody fusion
US9017334B2 (en) 2009-02-24 2015-04-28 Microport Orthopedics Holdings Inc. Patient specific surgical guide locator and mount
US8808303B2 (en) 2009-02-24 2014-08-19 Microport Orthopedics Holdings Inc. Orthopedic surgical guide
US8808297B2 (en) 2009-02-24 2014-08-19 Microport Orthopedics Holdings Inc. Orthopedic surgical guide
EP2410951A1 (en) * 2009-03-23 2012-02-01 Chi 2 Gel Ltd. Restorative device for intervertebral discs
US9526620B2 (en) 2009-03-30 2016-12-27 DePuy Synthes Products, Inc. Zero profile spinal fusion cage
WO2010115138A2 (en) * 2009-04-03 2010-10-07 Light Cure, Llc Devices and injectable or implantable compositions for intervertebral fusion
US8210729B2 (en) 2009-04-06 2012-07-03 Illuminoss Medical, Inc. Attachment system for light-conducting fibers
US8512338B2 (en) 2009-04-07 2013-08-20 Illuminoss Medical, Inc. Photodynamic bone stabilization systems and methods for reinforcing bone
US8636803B2 (en) 2009-04-07 2014-01-28 Spinal Stabilization Technologies, Llc Percutaneous implantable nuclear prosthesis
WO2010121147A1 (en) 2009-04-16 2010-10-21 Conformis, Inc. Patient-specific joint arthroplasty devices for ligament repair
US20100298832A1 (en) 2009-05-20 2010-11-25 Osseon Therapeutics, Inc. Steerable curvable vertebroplasty drill
AU2010328680B2 (en) 2009-08-19 2014-10-23 Illuminoss Medical, Inc. Devices and methods for bone alignment, stabilization and distraction
US8403988B2 (en) * 2009-09-11 2013-03-26 Depuy Spine, Inc. Minimally invasive intervertebral staple distraction devices
US9615933B2 (en) * 2009-09-15 2017-04-11 DePuy Synthes Products, Inc. Expandable ring intervertebral fusion device
US8211126B2 (en) 2009-09-22 2012-07-03 Jmea Corporation Tissue repair system
US9028553B2 (en) 2009-11-05 2015-05-12 DePuy Synthes Products, Inc. Self-pivoting spinal implant and associated instrumentation
US9168138B2 (en) 2009-12-09 2015-10-27 DePuy Synthes Products, Inc. Aspirating implants and method of bony regeneration
US9393129B2 (en) 2009-12-10 2016-07-19 DePuy Synthes Products, Inc. Bellows-like expandable interbody fusion cage
US8652153B2 (en) 2010-01-11 2014-02-18 Anulex Technologies, Inc. Intervertebral disc annulus repair system and bone anchor delivery tool
US9180137B2 (en) 2010-02-09 2015-11-10 Bone Support Ab Preparation of bone cement compositions
US8343224B2 (en) 2010-03-16 2013-01-01 Pinnacle Spine Group, Llc Intervertebral implants and graft delivery systems and methods
EP2563233B1 (en) 2010-04-29 2020-04-01 Dfine, Inc. System for use in treatment of vertebral fractures
US8684965B2 (en) 2010-06-21 2014-04-01 Illuminoss Medical, Inc. Photodynamic bone stabilization and drug delivery systems
US9282979B2 (en) 2010-06-24 2016-03-15 DePuy Synthes Products, Inc. Instruments and methods for non-parallel disc space preparation
US8979860B2 (en) 2010-06-24 2015-03-17 DePuy Synthes Products. LLC Enhanced cage insertion device
JP5850930B2 (ja) 2010-06-29 2016-02-03 ジンテス ゲゼルシャフト ミット ベシュレンクテル ハフツング 離反椎間インプラント
CA2804723A1 (en) 2010-07-15 2012-01-19 Nlt Spine Ltd. Surgical systems and methods for implanting deflectable implants
US9402732B2 (en) 2010-10-11 2016-08-02 DePuy Synthes Products, Inc. Expandable interspinous process spacer implant
US9179959B2 (en) 2010-12-22 2015-11-10 Illuminoss Medical, Inc. Systems and methods for treating conditions and diseases of the spine
EP2688518A4 (en) 2011-03-22 2014-08-20 Depuy Synthes Products Llc UNIVERSAL TEST METHOD FOR RIBBON IMPLANTS
CN103687645A (zh) 2011-07-19 2014-03-26 伊卢米诺斯医学有限公司 用于骨重建及稳定的装置和方法
WO2013059609A1 (en) 2011-10-19 2013-04-25 Illuminoss Medical, Inc. Systems and methods for joint stabilization
US9380932B1 (en) 2011-11-02 2016-07-05 Pinnacle Spine Group, Llc Retractor devices for minimally invasive access to the spine
US9486226B2 (en) 2012-04-18 2016-11-08 Conformis, Inc. Tibial guides, tools, and techniques for resecting the tibial plateau
EP3281609B1 (en) 2012-05-29 2019-02-27 NLT Spine Ltd. Expanding implant
US9675471B2 (en) 2012-06-11 2017-06-13 Conformis, Inc. Devices, techniques and methods for assessing joint spacing, balancing soft tissues and obtaining desired kinematics for joint implant components
US8939977B2 (en) 2012-07-10 2015-01-27 Illuminoss Medical, Inc. Systems and methods for separating bone fixation devices from introducer
US10022245B2 (en) 2012-12-17 2018-07-17 DePuy Synthes Products, Inc. Polyaxial articulating instrument
US9687281B2 (en) 2012-12-20 2017-06-27 Illuminoss Medical, Inc. Distal tip for bone fixation devices
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
WO2014117107A1 (en) 2013-01-28 2014-07-31 Cartiva, Inc. Systems and methods for orthopedic repair
US9737294B2 (en) 2013-01-28 2017-08-22 Cartiva, Inc. Method and system for orthopedic repair
PT2958603T (pt) 2013-02-20 2018-06-06 Bone Support Ab Endurecimento melhorado de substituto ósseo endurecível
US9717601B2 (en) 2013-02-28 2017-08-01 DePuy Synthes Products, Inc. Expandable intervertebral implant, system, kit and method
US9522070B2 (en) 2013-03-07 2016-12-20 Interventional Spine, Inc. Intervertebral implant
AU2014201372B2 (en) * 2013-03-13 2018-07-19 Howmedica Osteonics Corp. Selectively expanding spine cage with enhanced bone graft infusion
US9913728B2 (en) 2013-03-14 2018-03-13 Quandary Medical, Llc Spinal implants and implantation system
WO2014159739A1 (en) 2013-03-14 2014-10-02 Pinnacle Spine Group, Llc Interbody implants and graft delivery systems
US20140277467A1 (en) 2013-03-14 2014-09-18 Spinal Stabilization Technologies, Llc Prosthetic Spinal Disk Nucleus
US9295479B2 (en) 2013-03-14 2016-03-29 Spinal Stabilization Technologies, Llc Surgical device
US9603610B2 (en) 2013-03-15 2017-03-28 DePuy Synthes Products, Inc. Tools and methods for tissue removal
US10806593B2 (en) 2013-06-24 2020-10-20 DePuy Synthes Products, Inc. Cortical rim-supporting interbody device
US20140378980A1 (en) 2013-06-24 2014-12-25 Roman Lomeli Cortical Rim-Supporting Interbody Device
US10149770B2 (en) 2013-07-09 2018-12-11 Seaspine, Inc. Orthopedic implant with adjustable angle between tissue contact surfaces
WO2015063721A1 (en) 2013-10-31 2015-05-07 Nlt Spine Ltd. Adjustable implant
US9737411B2 (en) 2013-12-11 2017-08-22 Nlt Spine Ltd. Worm-gear actuated orthopedic implants and methods
WO2015198335A1 (en) 2014-06-25 2015-12-30 Nlt Spine Ltd. Expanding implant with hinged arms
EP3215069B1 (en) 2014-11-04 2023-03-08 Spinal Stabilization Technologies LLC Percutaneous implantable nuclear prosthesis
KR102464886B1 (ko) 2014-11-04 2022-11-08 스파이널 스태빌라이제이션 테크놀로지스, 엘엘씨 경피 이식형 핵 보철물
US11426290B2 (en) 2015-03-06 2022-08-30 DePuy Synthes Products, Inc. Expandable intervertebral implant, system, kit and method
US10575967B2 (en) 2015-09-01 2020-03-03 Spinal Stabilization Technologies Llc Implantable nuclear prosthesis
US11020160B2 (en) 2016-03-21 2021-06-01 Warsaw Orthopedic, Inc. Surgical injection system and method
US10285825B2 (en) * 2016-04-07 2019-05-14 Howmedica Osteonics Corp. Surgical insertion instruments
JP6995789B2 (ja) 2016-06-28 2022-01-17 イーアイティー・エマージング・インプラント・テクノロジーズ・ゲーエムベーハー 拡張可能かつ角度調節可能な椎間ケージ
CN109688980B (zh) 2016-06-28 2022-06-10 Eit 新兴移植技术股份有限公司 具有关节运动接头的可扩张和角度可调节的椎间笼
WO2018081279A1 (en) 2016-10-27 2018-05-03 Dfine, Inc. Articulating osteotome with cement delivery channel
WO2018098433A1 (en) 2016-11-28 2018-05-31 Dfine, Inc. Tumor ablation devices and related methods
US10470781B2 (en) 2016-12-09 2019-11-12 Dfine, Inc. Medical devices for treating hard tissues and related methods
US10888433B2 (en) 2016-12-14 2021-01-12 DePuy Synthes Products, Inc. Intervertebral implant inserter and related methods
WO2018129180A1 (en) 2017-01-06 2018-07-12 Dfine, Inc. Osteotome with a distal portion for simultaneous advancement and articulation
US11213402B2 (en) * 2017-01-11 2022-01-04 Loubert S. Suddaby Endoscopically implantable inflatable interbody fusion device
US10881522B2 (en) * 2017-02-09 2021-01-05 Nadi S Hibri Radially expandable annulus reinforcement prosthesis
WO2018185770A1 (en) 2017-04-05 2018-10-11 Setbone Medical Ltd. Property changing implant
US10398563B2 (en) 2017-05-08 2019-09-03 Medos International Sarl Expandable cage
US11344424B2 (en) 2017-06-14 2022-05-31 Medos International Sarl Expandable intervertebral implant and related methods
US10940016B2 (en) 2017-07-05 2021-03-09 Medos International Sarl Expandable intervertebral fusion cage
US10966843B2 (en) 2017-07-18 2021-04-06 DePuy Synthes Products, Inc. Implant inserters and related methods
US11045331B2 (en) 2017-08-14 2021-06-29 DePuy Synthes Products, Inc. Intervertebral implant inserters and related methods
CA3074834A1 (en) 2017-09-08 2019-03-14 Pioneer Surgical Technology, Inc. Intervertebral implants, instruments, and methods
EP3456297B1 (en) 2017-09-15 2023-10-04 Howmedica Osteonics Corp. Instruments for expandable interbody implants
USD907771S1 (en) 2017-10-09 2021-01-12 Pioneer Surgical Technology, Inc. Intervertebral implant
EP3813696B1 (en) 2018-06-27 2024-09-18 IlluminOss Medical, Inc. Systems for bone stabilization and fixation
JP7457712B2 (ja) 2018-09-04 2024-03-28 スパイナル スタビライゼーション テクノロジーズ リミテッド ライアビリティ カンパニー 植込み可能な髄核補綴物、キット、および関連する方法
US11446156B2 (en) 2018-10-25 2022-09-20 Medos International Sarl Expandable intervertebral implant, inserter instrument, and related methods
WO2020097339A1 (en) 2018-11-08 2020-05-14 Dfine, Inc. Tumor ablation device and related systems and methods
EP3975939A4 (en) 2019-05-29 2023-01-11 Wright Medical Technology, Inc. PREPARATION OF A THIBITAL BEAR TO RECEIVE A TIBIAL IMPLANT COMPONENT OF A REPLACEMENT ANKLE
US11986229B2 (en) 2019-09-18 2024-05-21 Merit Medical Systems, Inc. Osteotome with inflatable portion and multiwire articulation
US11426286B2 (en) 2020-03-06 2022-08-30 Eit Emerging Implant Technologies Gmbh Expandable intervertebral implant
US11376131B2 (en) * 2020-04-07 2022-07-05 Ethicon, Inc. Cortical rim-supporting interbody device and method
US11771562B2 (en) * 2021-01-28 2023-10-03 The Second Affiliated Hospital And Yuying Children's Hospital Of Wenzhou Medical University Balloon, medical device and medical procedure for discoplasty
US11850160B2 (en) 2021-03-26 2023-12-26 Medos International Sarl Expandable lordotic intervertebral fusion cage
US11752009B2 (en) 2021-04-06 2023-09-12 Medos International Sarl Expandable intervertebral fusion cage
US12090064B2 (en) 2022-03-01 2024-09-17 Medos International Sarl Stabilization members for expandable intervertebral implants, and related systems and methods

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4313434A (en) 1980-10-17 1982-02-02 David Segal Fracture fixation
GB8415265D0 (en) 1984-06-15 1984-07-18 Ici Plc Device
US4705519A (en) * 1985-02-27 1987-11-10 Hayes Separation, Inc. Repair material for use with bones
US4645503A (en) * 1985-08-27 1987-02-24 Orthomatrix Inc. Moldable bone-implant material
US4728570A (en) * 1985-10-29 1988-03-01 United States Surgical Corporation Calcium-hydroxide-treated polymeric implant matrial
US4714478A (en) 1986-01-17 1987-12-22 Fischer William B Prosthesis, method, and tool for installing same
FR2639823A1 (fr) * 1988-12-06 1990-06-08 Garcia Alain Remplacement du nucleus du disque intervertebral par un polyurethane polymerise in situ
US5037445A (en) * 1989-04-14 1991-08-06 United States Surgical Corporation Method and kit for molding surgical implants
JPH0645487B2 (ja) * 1989-05-19 1994-06-15 徳山曹達株式会社 硬化材
US5102413A (en) 1990-11-14 1992-04-07 Poddar Satish B Inflatable bone fixation device
US5192326A (en) * 1990-12-21 1993-03-09 Pfizer Hospital Products Group, Inc. Hydrogel bead intervertebral disc nucleus
CS277533B6 (en) 1990-12-29 1993-03-17 Krajicek Milan Fixed osteaosynthesis appliance
CA2070586C (en) * 1991-06-10 1995-11-28 Barry Eppley Prosthetic implant
US5423850A (en) 1993-10-01 1995-06-13 Berger; J. Lee Balloon compressor for internal fixation of bone fractures
US5480400A (en) 1993-10-01 1996-01-02 Berger; J. Lee Method and device for internal fixation of bone fractures
US5514137A (en) 1993-12-06 1996-05-07 Coutts; Richard D. Fixation of orthopedic devices
JP3333211B2 (ja) 1994-01-26 2002-10-15 レイリー，マーク・エイ 骨の治療に関する外科的方法で使用される、改良に係る拡張可能な装置
US5888220A (en) * 1994-05-06 1999-03-30 Advanced Bio Surfaces, Inc. Articulating joint repair
US5571189A (en) * 1994-05-20 1996-11-05 Kuslich; Stephen D. Expandable fabric implant for stabilizing the spinal motion segment
DE4424883A1 (de) * 1994-07-14 1996-01-18 Merck Patent Gmbh Femurprothese
US5681289A (en) 1995-08-14 1997-10-28 Medicinelodge Inc. Chemical dispensing system
JP2002505592A (ja) * 1996-11-15 2002-02-19 アドバンスト バイオ サーフェイシズ，インコーポレイティド 生体内原位置で組織を修復するのに用いる生体用材料システム
US6022376A (en) * 1997-06-06 2000-02-08 Raymedica, Inc. Percutaneous prosthetic spinal disc nucleus and method of manufacture
US5968999A (en) * 1997-10-28 1999-10-19 Charlotte-Mecklenburg Hospital Authority Bone cement compositions
US5951160A (en) 1997-11-20 1999-09-14 Biomet, Inc. Method and apparatus for packaging, mixing and delivering bone cement
US5997582A (en) 1998-05-01 1999-12-07 Weiss; James M. Hip replacement methods and apparatus

Also Published As

Publication number Publication date
US6332894B1 (en) 2001-12-25
DE60104918T2 (de) 2005-01-20
DE60104918D1 (de) 2004-09-23
AU772702B2 (en) 2004-05-06
JP2001276099A (ja) 2001-10-09
CA2337593A1 (en) 2001-09-07
EP1132061A3 (en) 2002-01-30
CA2337593C (en) 2008-08-05
EP1132061B1 (en) 2004-08-18
AU2485101A (en) 2001-09-13
ES2227068T3 (es) 2005-04-01
EP1132061A2 (en) 2001-09-12

Similar Documents

Publication Publication Date Title
JP4130535B2 (ja) 脊椎の隣接する椎骨の間に移植するための整形外科インプラント
US7507243B2 (en) Devices and method for augmenting a vertebral disc
AU2002246690B2 (en) Annulus- reinforcing band
US7198047B2 (en) Anchored anulus method
US7267690B2 (en) Interlocked modular disc nucleus prosthesis
US8231678B2 (en) Method of treating a herniated disc
AU2002246690A1 (en) Annulus- reinforcing band
JP2008521563A (ja) 脊椎間疾患処理用システム、装置及び方法
JP4891991B2 (ja) レールベースのモジュラー式円板髄核プロテーゼ
US7758649B2 (en) Reversibly deformable implant
KR100646835B1 (ko) 수핵을 충진 및 유지시키는 장치 및 방법
AU2007203365A1 (en) Annulus-reinforcing band and a method for stabilizing a spinal segment

Legal Events

Date Code Title Description
A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20041213

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20041213

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20080108

A521 Written amendment

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080324

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20080422

A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20080522

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20110530

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20110530

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20120530

Year of fee payment: 4

LAPS Cancellation because of no payment of annual fees