JP4121151B2 - 抗新生物薬および抗レトロウイルス薬として有用なアクリドンから誘導された化合物 - Google Patents

抗新生物薬および抗レトロウイルス薬として有用なアクリドンから誘導された化合物 Download PDF

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JP4121151B2
JP4121151B2 JP53745697A JP53745697A JP4121151B2 JP 4121151 B2 JP4121151 B2 JP 4121151B2 JP 53745697 A JP53745697 A JP 53745697A JP 53745697 A JP53745697 A JP 53745697A JP 4121151 B2 JP4121151 B2 JP 4121151B2
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Japan
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compound
compounds
hiv
cells
independently
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JP53745697A
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Japanese (ja)
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JP2000508662A (ja
JP2000508662A5 (enExample
Inventor
ミシェジャ，クリストファー・ジェイ
チョロディ，マレック・ダブリュー
ライス，ウィリアム・ジー
ターピン，ジェイムズ・エイ
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Government of the United States of America
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Government of the United States of America
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP53745697A 1996-04-12 1997-04-09 抗新生物薬および抗レトロウイルス薬として有用なアクリドンから誘導された化合物 Expired - Fee Related JP4121151B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1532696P 1996-04-12 1996-04-12
US60/015,326 1996-04-12
US3505097P 1997-01-22 1997-01-22
US60/035,050 1997-01-22
PCT/US1997/007070 WO1997038999A1 (en) 1996-04-12 1997-04-09 Acridone-derived compounds useful as antineoplastic and antiretroviral agents

Publications (3)

Publication Number Publication Date
JP2000508662A JP2000508662A (ja) 2000-07-11
JP2000508662A5 JP2000508662A5 (enExample) 2004-10-28
JP4121151B2 true JP4121151B2 (ja) 2008-07-23

Family

ID=26687242

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53745697A Expired - Fee Related JP4121151B2 (ja) 1996-04-12 1997-04-09 抗新生物薬および抗レトロウイルス薬として有用なアクリドンから誘導された化合物

Country Status (10)

Country Link
US (2) US6187775B1 (enExample)
EP (1) EP0892801B1 (enExample)
JP (1) JP4121151B2 (enExample)
AT (1) ATE211471T1 (enExample)
AU (1) AU725629B2 (enExample)
DE (1) DE69709857T2 (enExample)
DK (1) DK0892801T3 (enExample)
ES (1) ES2171260T3 (enExample)
PT (1) PT892801E (enExample)
WO (1) WO1997038999A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1293525B1 (it) * 1997-08-01 1999-03-01 Uni Degli Studi Camerino Bis-acridincarbossiammidi aventi attivita' antitumorale
WO2001066545A2 (en) * 2000-03-07 2001-09-13 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services 1,8-NAPHTHALIMIDE IMIDAZO[4,5,1-de]ACRIDONES WITH ANTI-TUMOR ACTIVITY
US7144843B2 (en) * 2001-01-31 2006-12-05 Meiji Seika Kaisha, Ltd. Pest controllers
US6670071B2 (en) * 2002-01-15 2003-12-30 Quallion Llc Electric storage battery construction and method of manufacture
CA2470365C (en) 2002-11-20 2011-05-17 Japan Tobacco Inc. 4-oxoquinoline compound and use thereof as hiv integrase inhibitor
RU2275361C3 (ru) * 2002-11-20 2021-10-01 Джапан Тобакко Инк. Соединение 4-оксохинолина и его применение в качестве ингибитора вич интегразы
US8512144B2 (en) * 2003-10-20 2013-08-20 Tipping Point Group, Llc Method and apparatus for providing secondary gaming machine functionality
MY134672A (en) 2004-05-20 2007-12-31 Japan Tobacco Inc Stable crystal of 4-oxoquinoline compound
WO2005113509A1 (en) 2004-05-20 2005-12-01 Japan Tobacco Inc. Novel 4-oxoquinoline compound and use thereof as hiv integrase inhibitor
ATE518866T1 (de) * 2004-06-30 2011-08-15 Council Scient Ind Res Über die piperazineinheit gebundene pyrroloä2,1- cüä1,4übenzodiazepin-napthalimid-konjugate und verfahren zu deren herstellung
US8377586B2 (en) * 2005-10-05 2013-02-19 California Institute Of Technology Fluoride ion electrochemical cell
US7829578B1 (en) 2005-12-12 2010-11-09 Oregon Health & Science University Aromatic ketones and uses thereof
WO2007092436A2 (en) * 2006-02-08 2007-08-16 Xanthus Pharmaceuticals, Inc. Compounds for treating inflammatory disorders, demyelinating disorders and cancers
IN2014CN00613A (enExample) 2006-03-06 2015-08-21 Japan Tobacco Inc
WO2007136858A2 (en) 2006-05-19 2007-11-29 H. Lee Moffitt Cancer Center & Research Institute Small molecule inhibitors of stat3 with anti-tumor activity
WO2008016661A2 (en) * 2006-08-02 2008-02-07 Xanthus Pharmaceuticals, Inc. Morpholino compounds for treating inflammatory and demyelinating diseases and cancers
AU2007316416A1 (en) * 2006-11-07 2008-05-15 Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Self-assembling nanoparticles composed of transmembrane peptides and their application for specific intra-tumor delivery of anti-cancer drugs
WO2008064011A1 (en) 2006-11-13 2008-05-29 The Government Of The U.S. Of America As Represented By The Department Of Veterans Affairs Acridone compounds
US8598354B2 (en) 2008-12-05 2013-12-03 University Of South Florida Compounds having antiparasitic or anti-infectious activity
PL3070078T3 (pl) * 2015-03-20 2018-02-28 Politechnika Gdańska Niesymetryczne bisakrydyny o działaniu przeciwnowotworowym i ich zastosowania

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9104548D0 (en) * 1991-03-05 1991-04-17 Cholody Wienlaw M Antineoplastic modified imidazoacridines
US5508289A (en) * 1994-03-14 1996-04-16 The United States America As Represented By The Department Of Health And Human Services Bis-acridone chemotherapeutic derivatives

Also Published As

Publication number Publication date
WO1997038999A1 (en) 1997-10-23
AU725629B2 (en) 2000-10-19
JP2000508662A (ja) 2000-07-11
ATE211471T1 (de) 2002-01-15
EP0892801A1 (en) 1999-01-27
PT892801E (pt) 2002-06-28
US20010009914A1 (en) 2001-07-26
US6541483B2 (en) 2003-04-01
AU2815797A (en) 1997-11-07
ES2171260T3 (es) 2002-09-01
DK0892801T3 (da) 2002-04-22
DE69709857D1 (de) 2002-02-28
EP0892801B1 (en) 2002-01-02
DE69709857T2 (de) 2002-08-29
US6187775B1 (en) 2001-02-13

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