ATE518866T1 - Über die piperazineinheit gebundene pyrroloä2,1- cüä1,4übenzodiazepin-napthalimid-konjugate und verfahren zu deren herstellung - Google Patents

Über die piperazineinheit gebundene pyrroloä2,1- cüä1,4übenzodiazepin-napthalimid-konjugate und verfahren zu deren herstellung

Info

Publication number
ATE518866T1
ATE518866T1 AT04745134T AT04745134T ATE518866T1 AT E518866 T1 ATE518866 T1 AT E518866T1 AT 04745134 T AT04745134 T AT 04745134T AT 04745134 T AT04745134 T AT 04745134T AT E518866 T1 ATE518866 T1 AT E518866T1
Authority
AT
Austria
Prior art keywords
napthalimide
pyrroloä2
cuä1
production
bonded via
Prior art date
Application number
AT04745134T
Other languages
English (en)
Inventor
A Kamal
R Rondla
G B R Khanna
Original Assignee
Council Scient Ind Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council Scient Ind Res filed Critical Council Scient Ind Res
Application granted granted Critical
Publication of ATE518866T1 publication Critical patent/ATE518866T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT04745134T 2004-06-30 2004-06-30 Über die piperazineinheit gebundene pyrroloä2,1- cüä1,4übenzodiazepin-napthalimid-konjugate und verfahren zu deren herstellung ATE518866T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2004/000191 WO2006003670A1 (en) 2004-06-30 2004-06-30 Pyrrolo[2,1-c][1,4]benzodiazepine-napthalimide conjugates linked through piperazine moiety and process for preparation thereof

Publications (1)

Publication Number Publication Date
ATE518866T1 true ATE518866T1 (de) 2011-08-15

Family

ID=34958092

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04745134T ATE518866T1 (de) 2004-06-30 2004-06-30 Über die piperazineinheit gebundene pyrroloä2,1- cüä1,4übenzodiazepin-napthalimid-konjugate und verfahren zu deren herstellung

Country Status (4)

Country Link
EP (1) EP1761537B1 (de)
JP (1) JP4638485B2 (de)
AT (1) ATE518866T1 (de)
WO (1) WO2006003670A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8288387B2 (en) * 2008-03-05 2012-10-16 Council Of Scientific & Industrial Research Napthalimide-benzimidazole hybrids as potential antitumor agents and process for the preparation thereof
EP2265613B1 (de) * 2008-03-05 2013-07-24 Council Of Scientific & Industrial Research Chinazolingebundene pyrrolo[2,1-c][1, 4]benzodiazepinhybride als potentielle antikrebsmittel und verfahren zu deren herstellung
JP2011515459A (ja) * 2008-03-26 2011-05-19 カウンシル オブ サイエンティフィック アンド インダストリアル リサーチ 抗癌剤候補としてのベンゾフェノンピペラジン結合ピロロ［２，１−ｃ］［１，４］ベンゾジアゼピンハイブリッド及びその調製方法
WO2010058414A1 (en) * 2008-11-19 2010-05-27 Council Of Scientific & Industrial Research Novel pyrroiol2,l-cu1.41benzodiazepine derivatives with dithiocarbamate side chains and process for the preparation thereof
EP2403855B1 (de) 2010-03-22 2013-05-01 Council of Scientific & Industrial Research Carbazolvernetzte pyrrolo[2,1-c][1,4]-benzodiazepinhybride als potentielle antikrebsmittel sowie verfahren zu ihrer herstellung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3707651A1 (de) * 1987-03-10 1988-09-22 Knoll Ag Bis-naphthalimide, ihre herstellung und verwendung
DE4232739A1 (de) * 1992-09-30 1994-03-31 Knoll Ag Neue asymmetrisch substituierte bis-Naphthalimide
ATE211471T1 (de) * 1996-04-12 2002-01-15 Us Gov Health & Human Serv Acridonderivate als antineoplastische-und antiretrovirale mittel
WO2001066545A2 (en) * 2000-03-07 2001-09-13 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services 1,8-NAPHTHALIMIDE IMIDAZO[4,5,1-de]ACRIDONES WITH ANTI-TUMOR ACTIVITY

Also Published As

Publication number Publication date
JP4638485B2 (ja) 2011-02-23
JP2007532692A (ja) 2007-11-15
WO2006003670A1 (en) 2006-01-12
EP1761537A1 (de) 2007-03-14
EP1761537B1 (de) 2011-08-03

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Legal Events

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