PT892801E - Compostos derivados de acridona uteis como agentes antineoplasicos e antiretrovirais - Google Patents
Compostos derivados de acridona uteis como agentes antineoplasicos e antiretroviraisInfo
- Publication number
- PT892801E PT892801E PT97922508T PT97922508T PT892801E PT 892801 E PT892801 E PT 892801E PT 97922508 T PT97922508 T PT 97922508T PT 97922508 T PT97922508 T PT 97922508T PT 892801 E PT892801 E PT 892801E
- Authority
- PT
- Portugal
- Prior art keywords
- acridone
- utilis
- antineoplastic
- compounds
- independently
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- GDALETGZDYOOGB-UHFFFAOYSA-N Acridone Natural products C1=C(O)C=C2N(C)C3=CC=CC=C3C(=O)C2=C1O GDALETGZDYOOGB-UHFFFAOYSA-N 0.000 title abstract 2
- FZEYVTFCMJSGMP-UHFFFAOYSA-N acridone Chemical compound C1=CC=C2C(=O)C3=CC=CC=C3NC2=C1 FZEYVTFCMJSGMP-UHFFFAOYSA-N 0.000 title abstract 2
- 229940034982 antineoplastic agent Drugs 0.000 title abstract 2
- 239000002246 antineoplastic agent Substances 0.000 title abstract 2
- 230000000118 anti-neoplastic effect Effects 0.000 title 1
- 229940124522 antiretrovirals Drugs 0.000 title 1
- 239000003903 antiretrovirus agent Substances 0.000 title 1
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1532696P | 1996-04-12 | 1996-04-12 | |
| US3505097P | 1997-01-22 | 1997-01-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT892801E true PT892801E (pt) | 2002-06-28 |
Family
ID=26687242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97922508T PT892801E (pt) | 1996-04-12 | 1997-04-09 | Compostos derivados de acridona uteis como agentes antineoplasicos e antiretrovirais |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6187775B1 (pt) |
| EP (1) | EP0892801B1 (pt) |
| JP (1) | JP4121151B2 (pt) |
| AT (1) | ATE211471T1 (pt) |
| AU (1) | AU725629B2 (pt) |
| DE (1) | DE69709857T2 (pt) |
| DK (1) | DK0892801T3 (pt) |
| ES (1) | ES2171260T3 (pt) |
| PT (1) | PT892801E (pt) |
| WO (1) | WO1997038999A1 (pt) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1293525B1 (it) * | 1997-08-01 | 1999-03-01 | Uni Degli Studi Camerino | Bis-acridincarbossiammidi aventi attivita' antitumorale |
| JP2003525940A (ja) * | 2000-03-07 | 2003-09-02 | アメリカ合衆国 | 抗−腫瘍活性を有する、１，８−ナフタルイミドイミダゾ〔４，５，１−ｄｅ〕アクリドン類 |
| ES2387265T3 (es) * | 2001-01-31 | 2012-09-19 | Meiji Seika Kaisha Ltd. | Derivados de triazoquinolona como agentes para el control de plagas |
| US6670071B2 (en) * | 2002-01-15 | 2003-12-30 | Quallion Llc | Electric storage battery construction and method of manufacture |
| CZ2004764A3 (cs) | 2002-11-20 | 2005-02-16 | Japan Tobacco Inc | 4-Oxochinolinová sloučenina a její použití jako inhibitoru HIV-integrázy |
| US8512144B2 (en) * | 2003-10-20 | 2013-08-20 | Tipping Point Group, Llc | Method and apparatus for providing secondary gaming machine functionality |
| US7531554B2 (en) | 2004-05-20 | 2009-05-12 | Japan Tobacco Inc. | 4-oxoquinoline compound and use thereof as HIV integrase inhibitor |
| MY134672A (en) | 2004-05-20 | 2007-12-31 | Japan Tobacco Inc | Stable crystal of 4-oxoquinoline compound |
| WO2006003670A1 (en) * | 2004-06-30 | 2006-01-12 | Council Of Scientific And Industrial Research | Pyrrolo[2,1-c][1,4]benzodiazepine-napthalimide conjugates linked through piperazine moiety and process for preparation thereof |
| US8377586B2 (en) * | 2005-10-05 | 2013-02-19 | California Institute Of Technology | Fluoride ion electrochemical cell |
| US7829578B1 (en) | 2005-12-12 | 2010-11-09 | Oregon Health & Science University | Aromatic ketones and uses thereof |
| WO2007092436A2 (en) * | 2006-02-08 | 2007-08-16 | Xanthus Pharmaceuticals, Inc. | Compounds for treating inflammatory disorders, demyelinating disorders and cancers |
| US8383819B2 (en) | 2006-03-06 | 2013-02-26 | Japan Tobacco Inc. | Method for producing 4-oxoquinoline compound |
| WO2007136858A2 (en) | 2006-05-19 | 2007-11-29 | H. Lee Moffitt Cancer Center & Research Institute | Small molecule inhibitors of stat3 with anti-tumor activity |
| WO2008016661A2 (en) * | 2006-08-02 | 2008-02-07 | Xanthus Pharmaceuticals, Inc. | Morpholino compounds for treating inflammatory and demyelinating diseases and cancers |
| WO2008058125A2 (en) * | 2006-11-07 | 2008-05-15 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Self-assembling nanoparticles composed of transmembrane peptides and their application for specific intra-tumor delivery of anti-cancer drugs |
| WO2008064011A1 (en) | 2006-11-13 | 2008-05-29 | The Government Of The U.S. Of America As Represented By The Department Of Veterans Affairs | Acridone compounds |
| US8598354B2 (en) | 2008-12-05 | 2013-12-03 | University Of South Florida | Compounds having antiparasitic or anti-infectious activity |
| PL3070078T3 (pl) * | 2015-03-20 | 2018-02-28 | Politechnika Gdańska | Niesymetryczne bisakrydyny o działaniu przeciwnowotworowym i ich zastosowania |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9104548D0 (en) * | 1991-03-05 | 1991-04-17 | Cholody Wienlaw M | Antineoplastic modified imidazoacridines |
| US5508289A (en) * | 1994-03-14 | 1996-04-16 | The United States America As Represented By The Department Of Health And Human Services | Bis-acridone chemotherapeutic derivatives |
-
1997
- 1997-04-09 AU AU28157/97A patent/AU725629B2/en not_active Ceased
- 1997-04-09 JP JP53745697A patent/JP4121151B2/ja not_active Expired - Fee Related
- 1997-04-09 ES ES97922508T patent/ES2171260T3/es not_active Expired - Lifetime
- 1997-04-09 PT PT97922508T patent/PT892801E/pt unknown
- 1997-04-09 WO PCT/US1997/007070 patent/WO1997038999A1/en active IP Right Grant
- 1997-04-09 US US09/155,141 patent/US6187775B1/en not_active Expired - Lifetime
- 1997-04-09 AT AT97922508T patent/ATE211471T1/de active
- 1997-04-09 EP EP97922508A patent/EP0892801B1/en not_active Expired - Lifetime
- 1997-04-09 DE DE69709857T patent/DE69709857T2/de not_active Expired - Lifetime
- 1997-04-09 DK DK97922508T patent/DK0892801T3/da active
-
2001
- 2001-01-15 US US09/760,047 patent/US6541483B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK0892801T3 (da) | 2002-04-22 |
| AU725629B2 (en) | 2000-10-19 |
| DE69709857D1 (de) | 2002-02-28 |
| EP0892801A1 (en) | 1999-01-27 |
| AU2815797A (en) | 1997-11-07 |
| US6541483B2 (en) | 2003-04-01 |
| JP2000508662A (ja) | 2000-07-11 |
| DE69709857T2 (de) | 2002-08-29 |
| ATE211471T1 (de) | 2002-01-15 |
| EP0892801B1 (en) | 2002-01-02 |
| JP4121151B2 (ja) | 2008-07-23 |
| US6187775B1 (en) | 2001-02-13 |
| WO1997038999A1 (en) | 1997-10-23 |
| ES2171260T3 (es) | 2002-09-01 |
| US20010009914A1 (en) | 2001-07-26 |
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