DK0906909T3 - Hydroxy- og polyhydroxyderivater af coumarin, deres fremstilling og antivirale virkning - Google Patents

Hydroxy- og polyhydroxyderivater af coumarin, deres fremstilling og antivirale virkning

Info

Publication number
DK0906909T3
DK0906909T3 DK98118508T DK98118508T DK0906909T3 DK 0906909 T3 DK0906909 T3 DK 0906909T3 DK 98118508 T DK98118508 T DK 98118508T DK 98118508 T DK98118508 T DK 98118508T DK 0906909 T3 DK0906909 T3 DK 0906909T3
Authority
DK
Denmark
Prior art keywords
coumarin
hydroxy
preparation
antiviral action
polyhydroxy derivatives
Prior art date
Application number
DK98118508T
Other languages
English (en)
Inventor
Mladen Prof Dr Trkovnik
Zrinka Ivezic
Original Assignee
Pliva Pharm & Chem Works
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Pharm & Chem Works filed Critical Pliva Pharm & Chem Works
Application granted granted Critical
Publication of DK0906909T3 publication Critical patent/DK0906909T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/44—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3
    • C07D311/46—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 unsubstituted in the carbocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/44—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/44—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3
    • C07D311/46—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 unsubstituted in the carbocyclic ring
    • C07D311/48—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 with one hydrogen atom in position 3 unsubstituted in the carbocyclic ring with two such benzopyran radicals linked together by a carbon chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/42—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4
    • C07D311/56—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms in positions 2 and 4 without hydrogen atoms in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK98118508T 1997-10-02 1998-09-30 Hydroxy- og polyhydroxyderivater af coumarin, deres fremstilling og antivirale virkning DK0906909T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HR970529A HRP970529B1 (en) 1997-10-02 1997-10-02 Novel hydroxy and polyhydroxy derivatives of cumarin, preparation thereof and antiviral action thereof

Publications (1)

Publication Number Publication Date
DK0906909T3 true DK0906909T3 (da) 2002-04-29

Family

ID=10946634

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98118508T DK0906909T3 (da) 1997-10-02 1998-09-30 Hydroxy- og polyhydroxyderivater af coumarin, deres fremstilling og antivirale virkning

Country Status (22)

Country Link
US (2) US6100409A (da)
EP (1) EP0906909B1 (da)
JP (3) JP3139996B2 (da)
CN (1) CN1101814C (da)
AT (1) ATE212625T1 (da)
AU (1) AU747394B2 (da)
BG (1) BG63543B1 (da)
CA (1) CA2246052A1 (da)
CZ (1) CZ314398A3 (da)
DE (1) DE69803642T2 (da)
DK (1) DK0906909T3 (da)
ES (1) ES2172072T3 (da)
HR (1) HRP970529B1 (da)
HU (1) HUP9802178A3 (da)
NO (1) NO984590L (da)
NZ (1) NZ332147A (da)
PL (1) PL328935A1 (da)
PT (1) PT906909E (da)
RU (1) RU2207338C2 (da)
SI (1) SI0906909T1 (da)
SK (1) SK283173B6 (da)
UA (1) UA63903C2 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP970529B1 (en) * 1997-10-02 2003-06-30 Pliva Pharm & Chem Works Novel hydroxy and polyhydroxy derivatives of cumarin, preparation thereof and antiviral action thereof
US20050075388A1 (en) * 2001-10-01 2005-04-07 Zrinka Ivezic Products of condensations of hydroxycoumarin derivatives with aromatic and aliphatic dialdehydes, their preparation and antiviral action thereof
HRP20030604A2 (en) * 2003-07-25 2005-04-30 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromenes, preparation thereof andtheir antiinflammatory action
HRP20030603A2 (en) 2003-07-25 2005-10-31 Pliva-Istra�iva�ki institut d.o.o. Substituted furochromene compounds of antiinflammatory action
DE102009029050A1 (de) * 2009-08-31 2011-03-03 Evonik Oxeno Gmbh Organophosphorverbindungen basierend auf Tetraphenol(TP)-substituierten Strukturen
JP6863067B2 (ja) * 2017-05-17 2021-04-21 Dic株式会社 δ−バレロラクトン骨格含有樹脂
CN111297851B (zh) * 2020-04-02 2021-03-23 中国农业科学院蜜蜂研究所 香豆素在蜜蜂抗病毒感染中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672607A (en) * 1993-01-29 1997-09-30 The United States Of America As Represented By The Department Of Health And Human Services Antiviral naphthoquinone compounds, compositions and uses thereof
HRP970529B1 (en) * 1997-10-02 2003-06-30 Pliva Pharm & Chem Works Novel hydroxy and polyhydroxy derivatives of cumarin, preparation thereof and antiviral action thereof

Also Published As

Publication number Publication date
ATE212625T1 (de) 2002-02-15
PT906909E (pt) 2002-07-31
RU2207338C2 (ru) 2003-06-27
HUP9802178A3 (en) 2002-05-28
EP0906909A1 (en) 1999-04-07
CN1101814C (zh) 2003-02-19
BG63543B1 (bg) 2002-04-30
JP2001089467A (ja) 2001-04-03
UA63903C2 (uk) 2004-02-16
NO984590L (no) 1999-04-06
HU9802178D0 (en) 1998-11-30
ES2172072T3 (es) 2002-09-16
AU747394B2 (en) 2002-05-16
CZ314398A3 (cs) 1999-05-12
JP2001089466A (ja) 2001-04-03
HRP970529A2 (en) 1999-06-30
SK283173B6 (sk) 2003-03-04
HUP9802178A2 (hu) 2000-05-28
BG102813A (en) 1999-07-30
DE69803642T2 (de) 2002-10-02
JP3139996B2 (ja) 2001-03-05
CN1220263A (zh) 1999-06-23
DE69803642D1 (de) 2002-03-14
SI0906909T1 (en) 2002-06-30
SK136798A3 (en) 1999-05-07
US6100409A (en) 2000-08-08
EP0906909B1 (en) 2002-01-30
CA2246052A1 (en) 1999-04-02
US6291518B1 (en) 2001-09-18
PL328935A1 (en) 1999-04-12
NZ332147A (en) 1999-05-28
JPH11158169A (ja) 1999-06-15
HRP970529B1 (en) 2003-06-30
AU8788698A (en) 1999-04-22
NO984590D0 (no) 1998-10-01

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