ATE198746T1 - Pyrimidinderivate und pharmazeutische zusammensetzungen - Google Patents
Pyrimidinderivate und pharmazeutische zusammensetzungenInfo
- Publication number
- ATE198746T1 ATE198746T1 AT95108380T AT95108380T ATE198746T1 AT E198746 T1 ATE198746 T1 AT E198746T1 AT 95108380 T AT95108380 T AT 95108380T AT 95108380 T AT95108380 T AT 95108380T AT E198746 T1 ATE198746 T1 AT E198746T1
- Authority
- AT
- Austria
- Prior art keywords
- carbon atoms
- integer
- alkyl
- nhc
- nhr
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/50—Three nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14227494 | 1994-06-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE198746T1 true ATE198746T1 (de) | 2001-02-15 |
Family
ID=15311548
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95108380T ATE198746T1 (de) | 1994-06-01 | 1995-06-01 | Pyrimidinderivate und pharmazeutische zusammensetzungen |
Country Status (6)
Country | Link |
---|---|
US (1) | US5585381A (de) |
EP (1) | EP0686631B1 (de) |
AT (1) | ATE198746T1 (de) |
AU (1) | AU679361B2 (de) |
CA (1) | CA2150609C (de) |
DE (1) | DE69519895T2 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI329105B (en) * | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
BR0313059B8 (pt) | 2002-07-29 | 2021-07-27 | Rigel Pharmaceuticals | composto, e, composição farmacêutica |
RS53109B (en) | 2003-07-30 | 2014-06-30 | Rigel Pharmaceuticals Inc. | 2,4 PIRIMIDINDIAMINE COMPOUNDS FOR USE IN TREATMENT OR PREVENTION OF AUTOIMMUNE DISEASES |
ATE540035T1 (de) * | 2004-11-24 | 2012-01-15 | Rigel Pharmaceuticals Inc | Spiro-2,4-pyrimidindiamin-verbindungen und ihre verwendungen |
US20060270694A1 (en) * | 2005-05-03 | 2006-11-30 | Rigel Pharmaceuticals, Inc. | JAK kinase inhibitors and their uses |
US9284301B2 (en) | 2010-03-25 | 2016-03-15 | Merck Sharp & Dohme Corp. | Soluble guanylate cyclase activators |
ES2564503T3 (es) | 2010-05-27 | 2016-03-23 | Merck Sharp & Dohme Corp. | Activadores de la guanilato-ciclasa soluble |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4748177A (en) * | 1984-03-26 | 1988-05-31 | Warner-Lambert Company | Guanine derivatives |
ZA875052B (en) | 1986-07-11 | 1989-03-29 | Du Pont | Angiotensin ii receptor blocking imidazoles |
US5138069A (en) | 1986-07-11 | 1992-08-11 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking imidazoles |
US5071867A (en) | 1990-02-28 | 1991-12-10 | Vanderbilt University | Treatment of chronic kidney disease with angiotensin I converting enzyme inhibitor |
DE69129611T2 (de) * | 1990-08-20 | 1998-12-17 | Eisai Co., Ltd., Tokio/Tokyo | Sulfonamid-Derivate |
IE912956A1 (en) | 1990-09-10 | 1992-03-11 | Abbott Lab | Angiotensin ii receptor antagonists |
JPH05320143A (ja) * | 1992-03-18 | 1993-12-03 | Mochida Pharmaceut Co Ltd | 新規ピリミジン誘導体 |
-
1995
- 1995-05-31 CA CA002150609A patent/CA2150609C/en not_active Expired - Fee Related
- 1995-05-31 US US08/454,629 patent/US5585381A/en not_active Expired - Fee Related
- 1995-06-01 EP EP95108380A patent/EP0686631B1/de not_active Expired - Lifetime
- 1995-06-01 AU AU20427/95A patent/AU679361B2/en not_active Ceased
- 1995-06-01 AT AT95108380T patent/ATE198746T1/de not_active IP Right Cessation
- 1995-06-01 DE DE69519895T patent/DE69519895T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69519895D1 (de) | 2001-02-22 |
EP0686631B1 (de) | 2001-01-17 |
US5585381A (en) | 1996-12-17 |
AU2042795A (en) | 1996-01-04 |
DE69519895T2 (de) | 2001-06-13 |
EP0686631A1 (de) | 1995-12-13 |
AU679361B2 (en) | 1997-06-26 |
CA2150609A1 (en) | 1995-12-02 |
CA2150609C (en) | 1998-12-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SE8802173D0 (sv) | Pyrimidine derivatives | |
DK0565549T3 (da) | Anvendelse af 1,3-oxathiolannucleosidanaloger til fremstilling af et præparat til behandling af hepatitis B | |
ES2082780T3 (es) | Derivados de acido bisfosfonico heterociclicos. | |
FI98729B (fi) | Menetelmä farmaseuttisesti vaikuttavan puriinijohdannaisen valmistamiseksi | |
PT992509E (pt) | Novos derivados macrolidos | |
ATE198746T1 (de) | Pyrimidinderivate und pharmazeutische zusammensetzungen | |
ES2055235T3 (es) | Composicion anti-inflamatoria y/o antialergica que comprende derivados de glutation. | |
ES2068413T3 (es) | Derivados de 4-fenilftalazina. | |
DK0420121T3 (da) | Antitumormiddel | |
NO890440D0 (no) | Fremgangsmaate for fremstilling av terapeutisk aktive isokinolinderivater. | |
ES2096572T3 (es) | Nuevos derivados de glucosidos de antraciclina y procedimiento para su preparacion. | |
NO173057C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive benzanilidderivater | |
NO985202L (no) | Anti-heliobacter pylori-preparater inneholdende 1-metylcarbapenemderivater | |
DK0420224T3 (da) | Anthihepatopatisk middel | |
ES2070154T3 (es) | Derivados de piridoindol y procedimientos para su preparacion. | |
PT855398E (pt) | Derivados sasquiterpeno tendo actividade antiviral | |
DK168284A (da) | Troponderivater | |
DK1264836T3 (da) | Fremgangsmåde til fremstilling af indolopyrrolocarbaxolderivater | |
DK0952157T3 (da) | 9a, 11b-dehydroderivater af 9-oxim-3-keto-6-0-methylerythromycin | |
GR3030952T3 (en) | Salmycins, a process for their preparation and their use as a pharmaceutical. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |