ES2070154T3 - Derivados de piridoindol y procedimientos para su preparacion. - Google Patents

Derivados de piridoindol y procedimientos para su preparacion.

Info

Publication number
ES2070154T3
ES2070154T3 ES89117498T ES89117498T ES2070154T3 ES 2070154 T3 ES2070154 T3 ES 2070154T3 ES 89117498 T ES89117498 T ES 89117498T ES 89117498 T ES89117498 T ES 89117498T ES 2070154 T3 ES2070154 T3 ES 2070154T3
Authority
ES
Spain
Prior art keywords
hydrogen
preparation
piridoindol
procedures
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89117498T
Other languages
English (en)
Inventor
Masayuki Kato
Kiyotaka Ito
Hisashi Takasugi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888822646A external-priority patent/GB8822646D0/en
Priority claimed from GB898903044A external-priority patent/GB8903044D0/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2070154T3 publication Critical patent/ES2070154T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

UN COMPUESTO DE LA FORMULA: EN DONDE R1 ES HIDROGENO, ALQUILO INFERIOR O ALQUENILO INFERIOR; R2 ES HIDROGENO, ALQUILO INFERIOR O HALOGENO; R3 ES IMIDIAZOLILO O PIRIDILO, PUDIENDO TENER CADA UNO DE ELLOS POSIBLE (S) SUBSTITUYENTE (S), Y R4 ES HIDROGENO, ALQUILO INFERIOR, ALQUENILO INFERIOR O HIDROXI (INFERIOR) ALQUILO Y R5 ES HIDROGENO, HIDROXILO O ACILOXILO, O R4 Y R5 ESTAN UNIDOS FORMANDO UN ENLACE ADICIONAL, Y SALES FARMACEUTICAMENTE ACEPTABLES DE EL, PROCESOS PARA SU PREPARACION Y COMPOSICIONES FARMACEUTICAS CONTENIENDO LAS MISMASEN ASOCIACION CON LOS PORTADORES O EXCIPIENTES SUBSTANCIALMENTE NO TOXICOS Y FARMACOLOGICAMENTE ACEPTABLES.
ES89117498T 1988-09-27 1989-09-21 Derivados de piridoindol y procedimientos para su preparacion. Expired - Lifetime ES2070154T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888822646A GB8822646D0 (en) 1988-09-27 1988-09-27 Pyridoindole derivatives & processes for preparation thereof
GB898903044A GB8903044D0 (en) 1989-02-10 1989-02-10 Pyridoindole derivatives and processes for preparation thereof

Publications (1)

Publication Number Publication Date
ES2070154T3 true ES2070154T3 (es) 1995-06-01

Family

ID=26294446

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89117498T Expired - Lifetime ES2070154T3 (es) 1988-09-27 1989-09-21 Derivados de piridoindol y procedimientos para su preparacion.

Country Status (20)

Country Link
US (1) US5141945A (es)
EP (1) EP0361317B1 (es)
JP (1) JPH02117675A (es)
KR (1) KR0143999B1 (es)
CN (1) CN1024552C (es)
AT (1) ATE120743T1 (es)
AU (1) AU627221B2 (es)
CA (1) CA1338474C (es)
DE (1) DE68922053T2 (es)
DK (1) DK170168B1 (es)
ES (1) ES2070154T3 (es)
FI (1) FI92200C (es)
GR (1) GR3015713T3 (es)
HK (1) HK102096A (es)
HU (2) HU206209B (es)
IE (1) IE67350B1 (es)
IL (1) IL91756A (es)
NO (1) NO172541C (es)
PT (1) PT91795B (es)
RU (1) RU2001915C1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5290785A (en) * 1988-09-27 1994-03-01 Fujisawa Pharmaceutical Co., Ltd. Therapeutic agent for ischemic diseases
US5173493A (en) * 1988-09-27 1992-12-22 Fujisawa Pharmaceutical Company, Ltd. Pyridoindole derivatives and processes for preparation thereof
GB9214184D0 (en) * 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
CA2157671A1 (en) * 1993-03-08 1994-09-15 Kiyotaka Katsuta Medicament for treating or preventing cerebrovascular diseases
DE69525354T2 (de) * 1994-09-19 2002-08-14 Fujisawa Pharmaceutical Co Eine neuartige medizinische verwendung eines 5ht 3-antagonisten
AU7000696A (en) * 1995-09-22 1997-04-09 Fujisawa Pharmaceutical Co., Ltd. Novel processes for producing pyridoindole derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1182150B (it) * 1984-01-25 1987-09-30 Glaxo Group Ltd Composti eterociclici tetraidrocarbozolonici, procedimenti per preparli e composizioni farmaceutiche che li contengono
GB8516083D0 (en) * 1985-06-25 1985-07-31 Glaxo Group Ltd Heterocyclic compounds
GB8518743D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Heterocyclic compounds
GR871809B (en) * 1986-11-28 1988-03-07 Glaxo Group Ltd Process for the preparation of tricyclic ketones

Also Published As

Publication number Publication date
HU211139A9 (en) 1995-10-30
EP0361317B1 (en) 1995-04-05
RU2001915C1 (ru) 1993-10-30
PT91795A (pt) 1990-03-30
US5141945A (en) 1992-08-25
IE892999L (en) 1990-03-27
EP0361317A2 (en) 1990-04-04
NO172541C (no) 1993-08-04
JPH02117675A (ja) 1990-05-02
DE68922053T2 (de) 1995-08-10
EP0361317A3 (en) 1991-07-24
NO172541B (no) 1993-04-26
HU206209B (en) 1992-09-28
DK170168B1 (da) 1995-06-06
KR900004733A (ko) 1990-04-12
CN1024552C (zh) 1994-05-18
AU627221B2 (en) 1992-08-20
PT91795B (pt) 1995-05-31
IE67350B1 (en) 1996-03-20
CN1041594A (zh) 1990-04-25
DK474089A (da) 1990-03-28
FI894506A0 (fi) 1989-09-25
JPH054392B2 (es) 1993-01-19
HK102096A (en) 1996-06-21
FI894506A (fi) 1990-03-28
AU4140689A (en) 1990-04-05
FI92200B (fi) 1994-06-30
FI92200C (fi) 1994-10-10
KR0143999B1 (ko) 1998-07-15
DK474089D0 (da) 1989-09-26
HUT51623A (en) 1990-05-28
GR3015713T3 (en) 1995-07-31
IL91756A0 (en) 1990-06-10
NO893820L (no) 1990-03-28
NO893820D0 (no) 1989-09-26
DE68922053D1 (de) 1995-05-11
IL91756A (en) 1993-07-08
CA1338474C (en) 1996-07-23
ATE120743T1 (de) 1995-04-15

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