FI890689A - 3-alkenyl-1-azabicyklo-/3.2.0/ -hept-2-en-2-karboxylsyrafoereningar. - Google Patents
3-alkenyl-1-azabicyklo-/3.2.0/ -hept-2-en-2-karboxylsyrafoereningar. Download PDFInfo
- Publication number
- FI890689A FI890689A FI890689A FI890689A FI890689A FI 890689 A FI890689 A FI 890689A FI 890689 A FI890689 A FI 890689A FI 890689 A FI890689 A FI 890689A FI 890689 A FI890689 A FI 890689A
- Authority
- FI
- Finland
- Prior art keywords
- alkyl
- carboxylsyrafoereningar
- azabicyclo
- hept
- alkenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/14—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB888804058A GB8804058D0 (en) | 1988-02-22 | 1988-02-22 | 3-alkenyl-1-azabicyclo(3 2 0)hept-2-ene-2-carboxylic acid compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
FI890689A0 FI890689A0 (fi) | 1989-02-14 |
FI890689A true FI890689A (fi) | 1989-08-23 |
Family
ID=10632122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI890689A FI890689A (fi) | 1988-02-22 | 1989-02-14 | 3-alkenyl-1-azabicyklo-/3.2.0/ -hept-2-en-2-karboxylsyrafoereningar. |
Country Status (18)
Country | Link |
---|---|
US (2) | US4923857A (fi) |
EP (1) | EP0330108B1 (fi) |
JP (1) | JP2748500B2 (fi) |
KR (1) | KR890013020A (fi) |
CN (1) | CN1037149A (fi) |
AT (1) | ATE132150T1 (fi) |
AU (1) | AU2983889A (fi) |
DE (1) | DE68925223T2 (fi) |
DK (1) | DK66789A (fi) |
FI (1) | FI890689A (fi) |
GB (1) | GB8804058D0 (fi) |
HU (1) | HUT49612A (fi) |
IE (1) | IE890500L (fi) |
IL (1) | IL89354A0 (fi) |
NO (1) | NO890723L (fi) |
OA (1) | OA09039A (fi) |
PT (1) | PT89769B (fi) |
ZA (1) | ZA89986B (fi) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2937911A1 (de) * | 1978-09-19 | 1980-03-27 | Daikin Ind Ltd | Fluor enthaltende phenylbenzoatverbindungen, verfahren zu ihrer herstellung und ihre verwendung |
US5102877A (en) * | 1989-04-28 | 1992-04-07 | Fujisawa Pharmaceutical Co., Ltd. | 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds |
EP0430037A3 (en) * | 1989-11-21 | 1992-05-27 | Banyu Pharmaceutical Co., Ltd. | Process for producing 2-carbon-substituted carbapenem derivatives |
US5258509A (en) * | 1989-11-21 | 1993-11-02 | Banyu Pharmaceutical Co., Ltd. | Process for producing 2-carbon-substituted carbapenem derivatives |
EP0465126A3 (en) * | 1990-06-29 | 1992-03-11 | Merck & Co. Inc. | Carbapenem antibacterial agents |
JPH06503803A (ja) * | 1990-07-27 | 1994-04-28 | 藤沢薬品工業株式会社 | 1―アザビシクロ[3.2.0]ヘプト―2―エン―2―カルボン酸化合物 |
US5189158A (en) * | 1991-03-20 | 1993-02-23 | American Cyanamid Company | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them |
US5371215A (en) * | 1991-03-20 | 1994-12-06 | American Cyanamid Company | 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them |
US6005138A (en) * | 1991-09-23 | 1999-12-21 | Florida State University | Tricyclic taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them |
US6395894B2 (en) | 1998-04-16 | 2002-05-28 | Philip J. Pye | Process for the synthesis of carbapenem intermidiates, and compounds produced |
CA2328219A1 (en) * | 1998-04-16 | 1999-10-21 | Merck & Co., Inc. | Titanium catalyzed preparation of carbapenem intermediates |
AU744644B2 (en) | 1998-06-17 | 2002-02-28 | Merck & Co., Inc. | Process for the synthesis of carbapenem intermediates, and compounds produced |
US6194568B1 (en) | 1998-07-13 | 2001-02-27 | Merck & Co., Inc. | Process for synthesizing carbapenem intermediates |
KR100351660B1 (ko) * | 2000-07-14 | 2002-09-05 | 한국화학연구원 | 2-아릴에테닐 카바페넴 유도체 및 그의 제조방법 |
WO2004041771A1 (ja) * | 2002-11-05 | 2004-05-21 | Lead Chemical Co.,Ltd. | 紫外線防御化合物 |
EP2314295B1 (en) | 2005-07-29 | 2015-01-28 | Resverlogix, Inc | Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices |
MX2009008099A (es) | 2007-02-01 | 2009-12-14 | Resverlogix Corp | Compuestos para la prevencion y tratamiento de enfermedades cardiovasculares. |
KR101629356B1 (ko) | 2008-06-26 | 2016-06-13 | 리스버로직스 코퍼레이션 | 퀴나졸리논 유도체의 제조방법 |
CA2747417C (en) | 2009-01-08 | 2017-01-03 | Resverlogix Corp. | Compounds for the prevention and treatment of cardiovascular disease |
US9238640B2 (en) | 2009-03-18 | 2016-01-19 | Resverlogix Corp. | Anti-inflammatory agents |
BRPI1014956B8 (pt) | 2009-04-22 | 2021-05-25 | Resverlogix Corp | agentes anti-inflamatórios |
EA028342B1 (ru) | 2011-09-09 | 2017-11-30 | Мерк Шарп И Доум Корп. | Способы лечения пневмонии |
JP5992049B2 (ja) | 2011-11-01 | 2016-09-14 | レスバーロジックス コーポレイション | 置換されたキナゾリノンのための経口速放性製剤 |
US8809314B1 (en) | 2012-09-07 | 2014-08-19 | Cubist Pharmacueticals, Inc. | Cephalosporin compound |
US8476425B1 (en) | 2012-09-27 | 2013-07-02 | Cubist Pharmaceuticals, Inc. | Tazobactam arginine compositions |
WO2014080290A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Cyclic amines as bromodomain inhibitors |
WO2014080291A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Biaryl derivatives as bromodomain inhibitors |
WO2014096965A2 (en) | 2012-12-21 | 2014-06-26 | Rvx Therapeutics Inc. | Novel heterocyclic compounds as bromodomain inhibitors |
US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
NZ700372A (en) | 2013-03-15 | 2016-01-29 | Merck Sharp & Dohme | Ceftolozane antibiotic compositions |
US20140274997A1 (en) | 2013-03-15 | 2014-09-18 | Cubist Pharmaceuticals, Inc. | Cephalosporin pharmaceutical compositions |
EP3043797B1 (en) | 2013-09-09 | 2020-04-08 | Merck Sharp & Dohme Corp. | Treating infections with ceftolozane/tazobactam in subjects having impaired renal function |
US8906898B1 (en) | 2013-09-27 | 2014-12-09 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
JP6903585B2 (ja) | 2015-03-13 | 2021-07-14 | レスバーロジックス コーポレイション | 補体関連疾患の治療のための組成物および治療方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4543257A (en) * | 1977-10-19 | 1985-09-24 | Merck & Co., Inc. | 1-Carba-2-penem-3-carboxylic acid |
US4348320A (en) * | 1976-11-19 | 1982-09-07 | Merck & Co., Inc. | Substituted azetidiones |
DE2966497D1 (en) * | 1978-10-24 | 1984-01-26 | Merck & Co Inc | 6-, 1- and 2-substituted-1-carbapen-2-em-3-carboxylic acids, processes for the preparation of such compounds and pharmaceutical composition comprising such compounds |
US4260627A (en) * | 1978-10-24 | 1981-04-07 | Merck & Co., Inc. | 1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids |
US4465632A (en) * | 1978-10-24 | 1984-08-14 | Merck & Co., Inc. | Process for preparing 1-6-and 2-substituted-1-carba-2-penem-3-carboxylic acids |
US4267188A (en) * | 1979-08-09 | 1981-05-12 | Merck & Co., Inc. | 5-Substituted-1-carba-pen-2-em-3-carboxylic acid |
US4552873A (en) * | 1981-08-19 | 1985-11-12 | Sankyo Company Limited | Carbapenem compounds, and compositions containing them |
US4729993A (en) * | 1984-12-13 | 1988-03-08 | Merck & Co., Inc. | Carbapenems and 1-methylcarbapenems having an externally alkylated mono- or bicyclic 2-quaternary heteroarylalkyl substituent |
CA1282415C (en) * | 1985-08-31 | 1991-04-02 | Yasuhiro Kuramoto | Azetidin-2-on derivatives and process for production thereof |
-
1988
- 1988-02-22 GB GB888804058A patent/GB8804058D0/en active Pending
-
1989
- 1989-02-08 ZA ZA89986A patent/ZA89986B/xx unknown
- 1989-02-10 AU AU29838/89A patent/AU2983889A/en not_active Abandoned
- 1989-02-13 DK DK066789A patent/DK66789A/da not_active Application Discontinuation
- 1989-02-14 FI FI890689A patent/FI890689A/fi not_active Application Discontinuation
- 1989-02-16 IE IE890500A patent/IE890500L/xx unknown
- 1989-02-17 US US07/312,061 patent/US4923857A/en not_active Expired - Fee Related
- 1989-02-18 DE DE68925223T patent/DE68925223T2/de not_active Expired - Fee Related
- 1989-02-18 EP EP89102859A patent/EP0330108B1/en not_active Expired - Lifetime
- 1989-02-18 AT AT89102859T patent/ATE132150T1/de not_active IP Right Cessation
- 1989-02-21 PT PT89769A patent/PT89769B/pt not_active IP Right Cessation
- 1989-02-21 CN CN89100880A patent/CN1037149A/zh active Pending
- 1989-02-21 HU HU89839A patent/HUT49612A/hu unknown
- 1989-02-21 IL IL89354A patent/IL89354A0/xx unknown
- 1989-02-21 NO NO89890723A patent/NO890723L/no unknown
- 1989-02-21 KR KR1019890002054A patent/KR890013020A/ko not_active Application Discontinuation
- 1989-02-22 OA OA59530A patent/OA09039A/xx unknown
- 1989-02-22 JP JP1042769A patent/JP2748500B2/ja not_active Expired - Lifetime
-
1990
- 1990-01-30 US US07/472,270 patent/US5081237A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0330108B1 (en) | 1995-12-27 |
IL89354A0 (en) | 1989-09-10 |
JPH021490A (ja) | 1990-01-05 |
GB8804058D0 (en) | 1988-03-23 |
CN1037149A (zh) | 1989-11-15 |
NO890723D0 (no) | 1989-02-21 |
IE890500L (en) | 1989-08-22 |
DE68925223D1 (de) | 1996-02-08 |
DK66789A (da) | 1989-08-23 |
OA09039A (fr) | 1991-03-31 |
DK66789D0 (da) | 1989-02-13 |
AU2983889A (en) | 1989-08-24 |
KR890013020A (ko) | 1989-09-20 |
NO890723L (no) | 1989-08-23 |
US5081237A (en) | 1992-01-14 |
DE68925223T2 (de) | 1996-06-13 |
JP2748500B2 (ja) | 1998-05-06 |
EP0330108A1 (en) | 1989-08-30 |
ZA89986B (en) | 1989-10-25 |
PT89769B (pt) | 1994-03-31 |
PT89769A (pt) | 1989-10-04 |
HUT49612A (en) | 1989-10-30 |
FI890689A0 (fi) | 1989-02-14 |
US4923857A (en) | 1990-05-08 |
ATE132150T1 (de) | 1996-01-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed |
Owner name: FUJISAWA PHARMACEUTICAL CO., LTD. |