ES2171260T3 - Compuestos derivados de acridona utiles como agentes antineoplasicos y antirretroviricos. - Google Patents

Compuestos derivados de acridona utiles como agentes antineoplasicos y antirretroviricos.

Info

Publication number
ES2171260T3
ES2171260T3 ES97922508T ES97922508T ES2171260T3 ES 2171260 T3 ES2171260 T3 ES 2171260T3 ES 97922508 T ES97922508 T ES 97922508T ES 97922508 T ES97922508 T ES 97922508T ES 2171260 T3 ES2171260 T3 ES 2171260T3
Authority
ES
Spain
Prior art keywords
useful
agents
acridona
independently
compounds derived
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97922508T
Other languages
English (en)
Spanish (es)
Inventor
Christopher J Michejda
Marek W Cholody
William G Rice
James A Turpin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Application granted granted Critical
Publication of ES2171260T3 publication Critical patent/ES2171260T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES97922508T 1996-04-12 1997-04-09 Compuestos derivados de acridona utiles como agentes antineoplasicos y antirretroviricos. Expired - Lifetime ES2171260T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1532696P 1996-04-12 1996-04-12
US3505097P 1997-01-22 1997-01-22

Publications (1)

Publication Number Publication Date
ES2171260T3 true ES2171260T3 (es) 2002-09-01

Family

ID=26687242

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97922508T Expired - Lifetime ES2171260T3 (es) 1996-04-12 1997-04-09 Compuestos derivados de acridona utiles como agentes antineoplasicos y antirretroviricos.

Country Status (10)

Country Link
US (2) US6187775B1 (enExample)
EP (1) EP0892801B1 (enExample)
JP (1) JP4121151B2 (enExample)
AT (1) ATE211471T1 (enExample)
AU (1) AU725629B2 (enExample)
DE (1) DE69709857T2 (enExample)
DK (1) DK0892801T3 (enExample)
ES (1) ES2171260T3 (enExample)
PT (1) PT892801E (enExample)
WO (1) WO1997038999A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1293525B1 (it) * 1997-08-01 1999-03-01 Uni Degli Studi Camerino Bis-acridincarbossiammidi aventi attivita' antitumorale
WO2001066545A2 (en) * 2000-03-07 2001-09-13 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services 1,8-NAPHTHALIMIDE IMIDAZO[4,5,1-de]ACRIDONES WITH ANTI-TUMOR ACTIVITY
US7144843B2 (en) * 2001-01-31 2006-12-05 Meiji Seika Kaisha, Ltd. Pest controllers
US6670071B2 (en) * 2002-01-15 2003-12-30 Quallion Llc Electric storage battery construction and method of manufacture
CA2470365C (en) 2002-11-20 2011-05-17 Japan Tobacco Inc. 4-oxoquinoline compound and use thereof as hiv integrase inhibitor
RU2275361C3 (ru) * 2002-11-20 2021-10-01 Джапан Тобакко Инк. Соединение 4-оксохинолина и его применение в качестве ингибитора вич интегразы
US8512144B2 (en) * 2003-10-20 2013-08-20 Tipping Point Group, Llc Method and apparatus for providing secondary gaming machine functionality
MY134672A (en) 2004-05-20 2007-12-31 Japan Tobacco Inc Stable crystal of 4-oxoquinoline compound
WO2005113509A1 (en) 2004-05-20 2005-12-01 Japan Tobacco Inc. Novel 4-oxoquinoline compound and use thereof as hiv integrase inhibitor
ATE518866T1 (de) * 2004-06-30 2011-08-15 Council Scient Ind Res Über die piperazineinheit gebundene pyrroloä2,1- cüä1,4übenzodiazepin-napthalimid-konjugate und verfahren zu deren herstellung
US8377586B2 (en) * 2005-10-05 2013-02-19 California Institute Of Technology Fluoride ion electrochemical cell
US7829578B1 (en) 2005-12-12 2010-11-09 Oregon Health & Science University Aromatic ketones and uses thereof
WO2007092436A2 (en) * 2006-02-08 2007-08-16 Xanthus Pharmaceuticals, Inc. Compounds for treating inflammatory disorders, demyelinating disorders and cancers
IN2014CN00613A (enExample) 2006-03-06 2015-08-21 Japan Tobacco Inc
WO2007136858A2 (en) 2006-05-19 2007-11-29 H. Lee Moffitt Cancer Center & Research Institute Small molecule inhibitors of stat3 with anti-tumor activity
WO2008016661A2 (en) * 2006-08-02 2008-02-07 Xanthus Pharmaceuticals, Inc. Morpholino compounds for treating inflammatory and demyelinating diseases and cancers
AU2007316416A1 (en) * 2006-11-07 2008-05-15 Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Self-assembling nanoparticles composed of transmembrane peptides and their application for specific intra-tumor delivery of anti-cancer drugs
WO2008064011A1 (en) 2006-11-13 2008-05-29 The Government Of The U.S. Of America As Represented By The Department Of Veterans Affairs Acridone compounds
US8598354B2 (en) 2008-12-05 2013-12-03 University Of South Florida Compounds having antiparasitic or anti-infectious activity
PL3070078T3 (pl) * 2015-03-20 2018-02-28 Politechnika Gdańska Niesymetryczne bisakrydyny o działaniu przeciwnowotworowym i ich zastosowania

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9104548D0 (en) * 1991-03-05 1991-04-17 Cholody Wienlaw M Antineoplastic modified imidazoacridines
US5508289A (en) * 1994-03-14 1996-04-16 The United States America As Represented By The Department Of Health And Human Services Bis-acridone chemotherapeutic derivatives

Also Published As

Publication number Publication date
WO1997038999A1 (en) 1997-10-23
AU725629B2 (en) 2000-10-19
JP2000508662A (ja) 2000-07-11
ATE211471T1 (de) 2002-01-15
EP0892801A1 (en) 1999-01-27
PT892801E (pt) 2002-06-28
US20010009914A1 (en) 2001-07-26
US6541483B2 (en) 2003-04-01
AU2815797A (en) 1997-11-07
DK0892801T3 (da) 2002-04-22
DE69709857D1 (de) 2002-02-28
EP0892801B1 (en) 2002-01-02
DE69709857T2 (de) 2002-08-29
US6187775B1 (en) 2001-02-13
JP4121151B2 (ja) 2008-07-23

Similar Documents

Publication Publication Date Title
ES2171260T3 (es) Compuestos derivados de acridona utiles como agentes antineoplasicos y antirretroviricos.
MX9403380A (es) Inhibidores de proteasa de vih utiles para el tratamiento de sida.
SV1995000048A (es) Compuestos ariltios
CY1108578T1 (el) Φαρμακευτικες συνθεσεις (κιτ) περιλαμβανοντας ενωσεις διϋδροπυριδινονης και εναν ανοσορυθμιστικο (ή εναν αντιφλεγμονωδη) παραγοντα και οι χρησεις αυτων
PA8588501A1 (es) Derivados antivirales de nucleósidos
ES2149267T3 (es) Carbonilos ciclicos substituidos y derivados de los mismos utiles como inhibidores de la proteasa retroviral.
ES2152252T3 (es) Indolocarbazolimidas y su empleo.
GT200000014A (es) Derivados de quinolin - 2 - ona sustituidos con heteroarilo utiles como agentes anticancerigenos.
FI20001231A7 (fi) 2-Deoksi-2,3-didehydro-N-asetyylineuramiinihapon johdannaisia ja niiden analogeja ja niiden käyttö antiviraalisina aineina
EA200500723A1 (ru) Соединения бензофурана, композиции и способы лечения и профилактики инфекций, вызванных вирусом гепатита c, и связанных с ним заболеваний
MX2024011695A (es) Compuestos de carbamoilpiridona triciclicos en puente y usos de estos
DK1124842T3 (da) Betulinsyrederivater anvendelige til behandling af neuroektodermale tumorer
CY1111567T1 (el) Ενδιαμεσα διβενζο (b,f) αζεπινης
BR9708114A (pt) Análogos xantona para o tratamento de doenças infecciosas.
PA8471001A1 (es) Mesilato de n-(3-etinilfenilamino)-6,7-bis(2-metoxietoxi)-4-quinazolinamina anhidro y monohidratado
NO20024486D0 (no) Forbedret behandling av neovaskularisering
DE69624813D1 (de) Robustaflavon und dessen derivate als antivirales mittel
CY1106444T1 (el) 17b-νιτρο-11β-αρυλοστepοειδη και παραγωγα αυτων ως ορμονικοι αγωνιστες ή ανταγωνιστες
ES2103577T3 (es) Compuestos antiviricos de naftoquinona, composiciones que los contienen y utilizaciones de estos compuestos.
DE69534361D1 (de) Therapeutische Quassinoid-Zubereitungen mit antineoplastischer, antiviraler und herbistatischer Wirkung
ATE124050T1 (de) Chirale 2-(phosphonomethoxy)propyl-guanine als antivirale agentien.
ES2101778T3 (es) Procedimiento para la obtencion de amino-benzodioxoles y -benzodioxanos y nuevos productos intermedios.
ATE139442T1 (de) Neue verwendung von linomide (r)
BR9905353A (pt) Compostos de indanilideno
ES2080193T3 (es) Anticuerpos monoclonales contra la gp120 de vih.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 892801

Country of ref document: ES