JP4112859B2 - 分子物質を結合させる方法 - Google Patents

分子物質を結合させる方法 Download PDF

Info

Publication number
JP4112859B2
JP4112859B2 JP2001535383A JP2001535383A JP4112859B2 JP 4112859 B2 JP4112859 B2 JP 4112859B2 JP 2001535383 A JP2001535383 A JP 2001535383A JP 2001535383 A JP2001535383 A JP 2001535383A JP 4112859 B2 JP4112859 B2 JP 4112859B2
Authority
JP
Japan
Prior art keywords
domain
protein
proline
rich
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2001535383A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003517300A5 (https=
JP2003517300A (ja
Inventor
ベーム、ゲラルト
シュミット、ウルリッヒ
パルティエール、クリストフ
ギュンター、コンスタンツェ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ACGT Progenomics AG
Original Assignee
ACGT Progenomics AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ACGT Progenomics AG filed Critical ACGT Progenomics AG
Publication of JP2003517300A publication Critical patent/JP2003517300A/ja
Publication of JP2003517300A5 publication Critical patent/JP2003517300A5/ja
Application granted granted Critical
Publication of JP4112859B2 publication Critical patent/JP4112859B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6901Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1075General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/22011Polyomaviridae, e.g. polyoma, SV40, JC
    • C12N2710/22022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2001535383A 1999-11-03 2000-11-03 分子物質を結合させる方法 Expired - Fee Related JP4112859B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19952956A DE19952956A1 (de) 1999-11-03 1999-11-03 Verfahren zur Verbindung von molekularen Substanzen
DE19952956.6 1999-11-03
PCT/EP2000/010873 WO2001032684A2 (de) 1999-11-03 2000-11-03 Verfahren zur verbindung von molekularen substanzen basierend auf der affinität der prolinreichen aminosäure-sequenzen und proteindomänem vom typ ww

Publications (3)

Publication Number Publication Date
JP2003517300A JP2003517300A (ja) 2003-05-27
JP2003517300A5 JP2003517300A5 (https=) 2006-01-05
JP4112859B2 true JP4112859B2 (ja) 2008-07-02

Family

ID=7927813

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001535383A Expired - Fee Related JP4112859B2 (ja) 1999-11-03 2000-11-03 分子物質を結合させる方法

Country Status (8)

Country Link
US (1) US7807782B2 (https=)
EP (1) EP1227848B1 (https=)
JP (1) JP4112859B2 (https=)
CN (1) CN100357314C (https=)
AT (1) ATE326984T1 (https=)
AU (1) AU2154801A (https=)
DE (2) DE19952956A1 (https=)
WO (1) WO2001032684A2 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4885476B2 (ja) * 2004-05-21 2012-02-29 株式会社日本触媒 タンパク質及び/又はペプチドの細胞内導入方法
CA2697032C (en) 2007-08-22 2021-09-14 The Regents Of The University Of California Activatable binding polypeptides and methods of identification and use thereof
US20100189651A1 (en) * 2009-01-12 2010-07-29 Cytomx Therapeutics, Llc Modified antibody compositions, methods of making and using thereof
JP5861223B2 (ja) * 2009-02-23 2016-02-16 サイトムエックス セラピューティクス, インク.CytomX Therapeutics, Inc. プロタンパク質およびその使用方法
JP6236948B2 (ja) * 2013-07-17 2017-11-29 東ソー株式会社 抗体精製用溶出液および当該溶出液を用いた抗体精製方法
GB201409558D0 (en) 2014-05-29 2014-07-16 Ucb Biopharma Sprl Method
GB201412659D0 (en) 2014-07-16 2014-08-27 Ucb Biopharma Sprl Molecules
GB201412658D0 (en) 2014-07-16 2014-08-27 Ucb Biopharma Sprl Molecules
GB201601073D0 (en) 2016-01-20 2016-03-02 Ucb Biopharma Sprl Antibodies
GB201601075D0 (en) 2016-01-20 2016-03-02 Ucb Biopharma Sprl Antibodies molecules
GB201601077D0 (en) 2016-01-20 2016-03-02 Ucb Biopharma Sprl Antibody molecule
GB201521391D0 (en) 2015-12-03 2016-01-20 Ucb Biopharma Sprl Antibodies
GB201521383D0 (en) 2015-12-03 2016-01-20 Ucb Biopharma Sprl And Ucb Celltech Method
GB201521389D0 (en) 2015-12-03 2016-01-20 Ucb Biopharma Sprl Method
GB201521382D0 (en) 2015-12-03 2016-01-20 Ucb Biopharma Sprl Antibodies
GB201521393D0 (en) 2015-12-03 2016-01-20 Ucb Biopharma Sprl Antibodies
US11202841B2 (en) * 2018-08-20 2021-12-21 The Trustees Of Indiana University Virus-enabled targeted vector for imaging
CN111979206B (zh) * 2019-05-24 2021-08-17 深圳瑞德林生物技术有限公司 固定化融合酶及用其制备谷胱甘肽的方法
CN117642413A (zh) * 2021-08-31 2024-03-01 富士胶片株式会社 化合物及使用了该化合物的标记生物物质
CN115951051B (zh) * 2022-10-18 2024-01-12 北京卓诚惠生生物科技股份有限公司 一种高灵敏度新型冠状病毒抗原胶体金检测试剂盒及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6072039A (en) 1991-04-19 2000-06-06 Rohm And Haas Company Hybrid polypeptide comparing a biotinylated avidin binding polypeptide fused to a polypeptide of interest
US6503703B1 (en) * 1995-05-19 2003-01-07 Mount Sinai School Of Medicine Of New York University Identification and use of antiviral compounds that inhibit interaction of host cell proteins and viral proteins required for viral replication
US6007544A (en) * 1996-06-14 1999-12-28 Beth Israel Deaconess Medical Center Catheter apparatus having an improved shape-memory alloy cuff and inflatable on-demand balloon for creating a bypass graft in-vivo
US7666221B2 (en) * 2000-05-01 2010-02-23 Endovascular Technologies, Inc. Lock modular graft component junctions
US7044962B2 (en) * 2002-06-25 2006-05-16 Scimed Life Systems, Inc. Implantable prosthesis with displaceable skirt

Also Published As

Publication number Publication date
CN100357314C (zh) 2007-12-26
WO2001032684A2 (de) 2001-05-10
DE50012831D1 (de) 2006-06-29
AU2154801A (en) 2001-05-14
DE19952956A1 (de) 2001-05-17
EP1227848B1 (de) 2006-05-24
US20060252130A1 (en) 2006-11-09
US7807782B2 (en) 2010-10-05
ATE326984T1 (de) 2006-06-15
CN1390140A (zh) 2003-01-08
WO2001032684A3 (de) 2002-04-18
EP1227848A2 (de) 2002-08-07
JP2003517300A (ja) 2003-05-27

Similar Documents

Publication Publication Date Title
JP4112859B2 (ja) 分子物質を結合させる方法
JP3280376B2 (ja) 多価抗原結合性蛋白質
ES2280231T3 (es) Polipeptidos quimericos, metodo para la produccion y usos de los mismos.
JP5014988B2 (ja) 発現増強ポリペプチド
CN101084237B (zh) 用于治疗、诊断和色谱层析的泛蛋白或γ晶体缀合物
AU2011333665B2 (en) Designed repeat proteins binding to serum albumin
US20140274759A1 (en) Modification of polypeptides
Gleiter et al. Coupling of antibodies via protein Z on modified polyoma virus‐like particles
JP6865584B2 (ja) 化合物の共有結合性コンジュゲーションのためのmTG基質
JP2008506659A5 (https=)
KR20150023957A (ko) 혈소판-유래 성장인자에 결합하는 설계된 안키린 반복 단백질
JP2014510518A (ja) Hsa関連組成物および使用方法
CN108699104B (zh) 具有转谷氨酰胺酶识别位点的fkbp结构域
JP6717725B2 (ja) 遺伝子操作した成長因子変異体
US8759488B2 (en) High stability streptavidin mutant proteins
JP2016147909A (ja) 機能性ポリペプチド
JP2001514263A (ja) ゴム弾性ペプチドを含む生体分子
JP2008530163A (ja) タンパク質およびポリペプチド多量体の分離のための活性化型ポリマーの使用
US20080139400A1 (en) Molecular display on multimeric protein scaffolds
Deci et al. Utilizing clathrin triskelions as carriers for spatially controlled multi-protein display
WO2025084336A1 (ja) Aavのキャプシドと標的受容体に同時に結合することができる分子
WO2022123240A1 (en) Purification of proteins

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20050610

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20050610

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20071016

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20080116

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20080123

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080215

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20080318

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20080410

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20110418

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20110418

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20120418

Year of fee payment: 4

LAPS Cancellation because of no payment of annual fees