DE19952956A1 - Verfahren zur Verbindung von molekularen Substanzen - Google Patents
Verfahren zur Verbindung von molekularen SubstanzenInfo
- Publication number
- DE19952956A1 DE19952956A1 DE19952956A DE19952956A DE19952956A1 DE 19952956 A1 DE19952956 A1 DE 19952956A1 DE 19952956 A DE19952956 A DE 19952956A DE 19952956 A DE19952956 A DE 19952956A DE 19952956 A1 DE19952956 A1 DE 19952956A1
- Authority
- DE
- Germany
- Prior art keywords
- domain
- proline
- protein
- rich
- molecular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/22011—Polyomaviridae, e.g. polyoma, SV40, JC
- C12N2710/22022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Peptides Or Proteins (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19952956A DE19952956A1 (de) | 1999-11-03 | 1999-11-03 | Verfahren zur Verbindung von molekularen Substanzen |
| AU21548/01A AU2154801A (en) | 1999-11-03 | 2000-11-03 | Method for linking molecular substances |
| AT00984960T ATE326984T1 (de) | 1999-11-03 | 2000-11-03 | Verfahren zur verbindung von molekularen substanzen |
| CNB008153167A CN100357314C (zh) | 1999-11-03 | 2000-11-03 | 一种分子物质连接的方法 |
| DE50012831T DE50012831D1 (de) | 1999-11-03 | 2000-11-03 | Verfahren zur verbindung von molekularen substanzen |
| EP00984960A EP1227848B1 (de) | 1999-11-03 | 2000-11-03 | Verfahren zur verbindung von molekularen substanzen |
| JP2001535383A JP4112859B2 (ja) | 1999-11-03 | 2000-11-03 | 分子物質を結合させる方法 |
| PCT/EP2000/010873 WO2001032684A2 (de) | 1999-11-03 | 2000-11-03 | Verfahren zur verbindung von molekularen substanzen basierend auf der affinität der prolinreichen aminosäure-sequenzen und proteindomänem vom typ ww |
| US11/446,587 US7807782B2 (en) | 1999-11-03 | 2006-06-01 | Method for linking molecular substances |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19952956A DE19952956A1 (de) | 1999-11-03 | 1999-11-03 | Verfahren zur Verbindung von molekularen Substanzen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE19952956A1 true DE19952956A1 (de) | 2001-05-17 |
Family
ID=7927813
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19952956A Withdrawn DE19952956A1 (de) | 1999-11-03 | 1999-11-03 | Verfahren zur Verbindung von molekularen Substanzen |
| DE50012831T Expired - Lifetime DE50012831D1 (de) | 1999-11-03 | 2000-11-03 | Verfahren zur verbindung von molekularen substanzen |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE50012831T Expired - Lifetime DE50012831D1 (de) | 1999-11-03 | 2000-11-03 | Verfahren zur verbindung von molekularen substanzen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7807782B2 (https=) |
| EP (1) | EP1227848B1 (https=) |
| JP (1) | JP4112859B2 (https=) |
| CN (1) | CN100357314C (https=) |
| AT (1) | ATE326984T1 (https=) |
| AU (1) | AU2154801A (https=) |
| DE (2) | DE19952956A1 (https=) |
| WO (1) | WO2001032684A2 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4885476B2 (ja) * | 2004-05-21 | 2012-02-29 | 株式会社日本触媒 | タンパク質及び/又はペプチドの細胞内導入方法 |
| CA2697032C (en) | 2007-08-22 | 2021-09-14 | The Regents Of The University Of California | Activatable binding polypeptides and methods of identification and use thereof |
| US20100189651A1 (en) * | 2009-01-12 | 2010-07-29 | Cytomx Therapeutics, Llc | Modified antibody compositions, methods of making and using thereof |
| JP5861223B2 (ja) * | 2009-02-23 | 2016-02-16 | サイトムエックス セラピューティクス, インク.CytomX Therapeutics, Inc. | プロタンパク質およびその使用方法 |
| JP6236948B2 (ja) * | 2013-07-17 | 2017-11-29 | 東ソー株式会社 | 抗体精製用溶出液および当該溶出液を用いた抗体精製方法 |
| GB201409558D0 (en) | 2014-05-29 | 2014-07-16 | Ucb Biopharma Sprl | Method |
| GB201412659D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| GB201412658D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| GB201601073D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibodies |
| GB201601075D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibodies molecules |
| GB201601077D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibody molecule |
| GB201521391D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521383D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl And Ucb Celltech | Method |
| GB201521389D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Method |
| GB201521382D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521393D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| US11202841B2 (en) * | 2018-08-20 | 2021-12-21 | The Trustees Of Indiana University | Virus-enabled targeted vector for imaging |
| CN111979206B (zh) * | 2019-05-24 | 2021-08-17 | 深圳瑞德林生物技术有限公司 | 固定化融合酶及用其制备谷胱甘肽的方法 |
| CN117642413A (zh) * | 2021-08-31 | 2024-03-01 | 富士胶片株式会社 | 化合物及使用了该化合物的标记生物物质 |
| CN115951051B (zh) * | 2022-10-18 | 2024-01-12 | 北京卓诚惠生生物科技股份有限公司 | 一种高灵敏度新型冠状病毒抗原胶体金检测试剂盒及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6072039A (en) | 1991-04-19 | 2000-06-06 | Rohm And Haas Company | Hybrid polypeptide comparing a biotinylated avidin binding polypeptide fused to a polypeptide of interest |
| US6503703B1 (en) * | 1995-05-19 | 2003-01-07 | Mount Sinai School Of Medicine Of New York University | Identification and use of antiviral compounds that inhibit interaction of host cell proteins and viral proteins required for viral replication |
| US6007544A (en) * | 1996-06-14 | 1999-12-28 | Beth Israel Deaconess Medical Center | Catheter apparatus having an improved shape-memory alloy cuff and inflatable on-demand balloon for creating a bypass graft in-vivo |
| US7666221B2 (en) * | 2000-05-01 | 2010-02-23 | Endovascular Technologies, Inc. | Lock modular graft component junctions |
| US7044962B2 (en) * | 2002-06-25 | 2006-05-16 | Scimed Life Systems, Inc. | Implantable prosthesis with displaceable skirt |
-
1999
- 1999-11-03 DE DE19952956A patent/DE19952956A1/de not_active Withdrawn
-
2000
- 2000-11-03 AT AT00984960T patent/ATE326984T1/de not_active IP Right Cessation
- 2000-11-03 AU AU21548/01A patent/AU2154801A/en not_active Abandoned
- 2000-11-03 CN CNB008153167A patent/CN100357314C/zh not_active Expired - Fee Related
- 2000-11-03 JP JP2001535383A patent/JP4112859B2/ja not_active Expired - Fee Related
- 2000-11-03 EP EP00984960A patent/EP1227848B1/de not_active Expired - Lifetime
- 2000-11-03 WO PCT/EP2000/010873 patent/WO2001032684A2/de not_active Ceased
- 2000-11-03 DE DE50012831T patent/DE50012831D1/de not_active Expired - Lifetime
-
2006
- 2006-06-01 US US11/446,587 patent/US7807782B2/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| J. of Virology, Apr. 1999, S. 2921-2929. NATO ASI Series Vol. H 102, 1997, S. 45-48 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100357314C (zh) | 2007-12-26 |
| WO2001032684A2 (de) | 2001-05-10 |
| DE50012831D1 (de) | 2006-06-29 |
| JP4112859B2 (ja) | 2008-07-02 |
| AU2154801A (en) | 2001-05-14 |
| EP1227848B1 (de) | 2006-05-24 |
| US20060252130A1 (en) | 2006-11-09 |
| US7807782B2 (en) | 2010-10-05 |
| ATE326984T1 (de) | 2006-06-15 |
| CN1390140A (zh) | 2003-01-08 |
| WO2001032684A3 (de) | 2002-04-18 |
| EP1227848A2 (de) | 2002-08-07 |
| JP2003517300A (ja) | 2003-05-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1227848B1 (de) | Verfahren zur verbindung von molekularen substanzen | |
| DE69010206T2 (de) | Stabilisierte protein- oder peptidkonjugate. | |
| DE60033405T2 (de) | Chimäre polypeptide, verfahren zur herstellung und verwendung dafür | |
| DE69233068T2 (de) | Serin-reiche peptidlinker | |
| DE69633175T2 (de) | Multimere proteine | |
| EP1270725B1 (de) | Anticaline | |
| DE69309472T2 (de) | Fusionsproteine von monomeren und dimeren von antikörperfragmenten | |
| EP1675623B1 (de) | Ubiquitin oder gamma-kristallin-konjugate zur verwendung in therapie, diagnose und chromatographie | |
| EP2542567B1 (de) | Selektive anreicherung von antikörpern | |
| CN109400693A (zh) | 新型proNGF突变体及其在生产β-NGF中的用途 | |
| DE19618797C2 (de) | Vehikel zum Transport molekularer Substanz | |
| WO1996002574A1 (de) | Verfahren zur modifizierung der stabilität von antikörpern | |
| DE69033937T2 (de) | Verfahren zur Herstellung von genetischen Vektoren zur Expression vom Nerven-Wachstumsfaktor in eukaryotischen Zellen | |
| DE69025211T2 (de) | Protein-Antikrebsmittel | |
| DE4344350C2 (de) | Bakterien zur Herstellung stabiler Fusionsproteine und Verfahren zu deren Nachweis | |
| CN120399090A (zh) | 融合促溶短肽和细胞穿透肽的重组狂犬病病毒纳米抗体及在制备狂犬病防治产品中的应用 | |
| WO2012017069A1 (de) | Linkerpeptid und seine verwendung in fusionsproteinen | |
| DE19916224C1 (de) | Synthetisches biologisch aktives Molekül | |
| EP1232257B1 (de) | Modulare transportsysteme für molekulare substanzen und deren herstellung und verwendung | |
| DE60305940T2 (de) | Modifizierte therapeutische mittel | |
| EP0453456B1 (de) | Pdgf-a, pdgf-aa, pdgf-ab, herstellungsverfahren und sie enthaltende arzneimittel | |
| DE10238846A1 (de) | Aktive Fusionsproteine und Verfahren zu ihrer Herstellung | |
| AT511130A2 (de) | Polypeptidmaterial mit flexiblen Poreneigenschaften | |
| DE19735105A1 (de) | Transportsystem zur Einbringung von Proteinen in Zielzellen mit Hilfe eines Fusionsproteins, Nucleinsäurekonstrukte kodierend für die Komponenten des Transportsystems und Arzneimittel, die Komponenten des Transportsystems umfassen | |
| EP1228199B1 (de) | Verfahren zur gerichteten verpackung von molekularen substanzen in proteinhüllen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OP8 | Request for examination as to paragraph 44 patent law | ||
| 8139 | Disposal/non-payment of the annual fee |