JP4086315B2 - 調節遺伝子およびその使用 - Google Patents

調節遺伝子およびその使用 Download PDF

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Publication number
JP4086315B2
JP4086315B2 JP51411097A JP51411097A JP4086315B2 JP 4086315 B2 JP4086315 B2 JP 4086315B2 JP 51411097 A JP51411097 A JP 51411097A JP 51411097 A JP51411097 A JP 51411097A JP 4086315 B2 JP4086315 B2 JP 4086315B2
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protein
sequence
fos
nucleotide
cells
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Expired - Fee Related
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JP51411097A
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Japanese (ja)
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JP2001501442A (ja
JP2001501442A5 (https=
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サルバトーレ オリビエロ，
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ユニベルシタ デグリ スチュディ ディ シエナ
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26307843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP4086315(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9519928.7A external-priority patent/GB9519928D0/en
Priority claimed from GBGB9612368.2A external-priority patent/GB9612368D0/en
Application filed by ユニベルシタ デグリ スチュディ ディ シエナ filed Critical ユニベルシタ デグリ スチュディ ディ シエナ
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Publication of JP2001501442A5 publication Critical patent/JP2001501442A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
JP51411097A 1995-09-29 1996-09-30 調節遺伝子およびその使用 Expired - Fee Related JP4086315B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9519928.7 1995-09-29
GBGB9519928.7A GB9519928D0 (en) 1995-09-29 1995-09-29 Regulated genes and uses thereof
GB9612368.2 1996-06-13
GBGB9612368.2A GB9612368D0 (en) 1996-06-13 1996-06-13 Regulated genes and uses thereof
PCT/IB1996/001113 WO1997012972A2 (en) 1995-09-29 1996-09-30 Regulated genes and uses thereof

Publications (3)

Publication Number Publication Date
JP2001501442A JP2001501442A (ja) 2001-02-06
JP2001501442A5 JP2001501442A5 (https=) 2004-09-30
JP4086315B2 true JP4086315B2 (ja) 2008-05-14

Family

ID=26307843

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51411097A Expired - Fee Related JP4086315B2 (ja) 1995-09-29 1996-09-30 調節遺伝子およびその使用

Country Status (11)

Country Link
US (1) US8383788B2 (https=)
EP (2) EP1553182B1 (https=)
JP (1) JP4086315B2 (https=)
AT (2) ATE459715T1 (https=)
AU (1) AU7142996A (https=)
CA (1) CA2230957A1 (https=)
DE (2) DE69638142D1 (https=)
ES (2) ES2341864T3 (https=)
IL (1) IL123649A0 (https=)
NO (1) NO981353D0 (https=)
WO (1) WO1997012972A2 (https=)

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US6824777B1 (en) 1992-10-09 2004-11-30 Licentia Ltd. Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy
US7423125B2 (en) 1995-08-01 2008-09-09 Vegenics Limited Antibodies to VEGF-C
ES2202469T5 (es) 1995-09-08 2011-06-06 Genentech, Inc. Proteína relacionada con el vegf.
DE69638142D1 (de) 1995-09-29 2010-04-15 Univ Siena Regulierte Gene und ihre Verwendungen
WO1998002543A1 (fr) * 1996-07-15 1998-01-22 Chugai Research Institute For Molecular Medicine, Inc. Nouveaux facteurs analogues au vegf
EP1283268A3 (en) * 1996-08-23 2004-01-02 Ludwig Institute For Cancer Research Recombinant vascular endothelial cell growth factor D (VEGF-D)
AU5439998A (en) * 1996-12-06 1998-06-29 Zymogenetics Inc. Vascular endothelial growth factor
US7125714B2 (en) 1997-02-05 2006-10-24 Licentia Ltd. Progenitor cell materials and methods
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA2315977A1 (en) * 1997-12-24 1999-07-08 Ludwig Institute For Cancer Research Expression vectors and cell lines expressing vascular endothelial growth factor d, and method of treating melanomas
DE19847422C1 (de) * 1998-10-14 2000-01-13 Forschungszentrum Juelich Gmbh Chinese-Hamster-Ovary-Zellen zur Produktion von Proteinen
DK1137773T3 (da) 1998-12-07 2008-12-08 Zymogenetics Inc Væsktfaktorhomolog ZVEGF3
WO2001012669A1 (en) * 1999-08-16 2001-02-22 Universita' Degli Studi Di Siena Vegf-d and angiogenic use thereof
AU2001239884B2 (en) 2000-02-25 2006-08-10 Vegenics Limited Materials and methods involving hybrid vascular endothelial growth factor DNAs and proteins and screening methods for modulators
US7611711B2 (en) 2001-01-17 2009-11-03 Vegenics Limited VEGFR-3 inhibitor materials and methods
CA2435503C (en) 2001-01-19 2011-02-22 Ludwig Institute For Cancer Research Flt4(vegfr-3) as a target for tumor imaging and anti-tumor therapy
CN1555488A (zh) * 2001-07-12 2004-12-15 路德维格癌症研究院 淋巴管内皮细胞物质及方法
US20030113324A1 (en) * 2001-10-01 2003-06-19 Kari Alitalo Neuropilin/VEGF-C/VEGFR-3 materials and methods
US20040214766A1 (en) * 2001-10-01 2004-10-28 Kari Alitalo VEGF-C or VEGF-D materials and methods for treatment of neuropathologies
US20040248796A1 (en) * 2003-02-04 2004-12-09 Kari Alitalo VEGF-B and PDGF modulation of stem cells
EP1635860A2 (en) * 2003-06-12 2006-03-22 Ludwig Institute For Cancer Research Use of vegf-c or vegf-d in reconstructive surgery
WO2005016963A2 (en) * 2003-06-12 2005-02-24 Ludwig Institute For Cancer Research Heparin binding veger-3 ligands
WO2005087177A2 (en) 2004-03-05 2005-09-22 Ludwig Institute For Cancer Research Chimeric anti-vegf-d antibodies and humanized anti-vegf-d antibodies and methods of using same
ITRM20050367A1 (it) * 2005-07-08 2007-01-09 Univ Siena Uso del vegf-d o di suoi frammenti funzionalmente attivi per la ricostruzione o per la riparazione ossea.
EP1919944B1 (en) 2005-08-15 2011-03-23 Vegenics Pty Ltd Modified vegf and pdgf with improved angiogenic properties
WO2008093246A2 (en) 2007-02-02 2008-08-07 Vegenics Limited Vegf receptor antagonist for treating organ transplant alloimmunity and arteriosclerosis
US8571840B2 (en) * 2007-03-28 2013-10-29 Autodesk, Inc. Constraint reduction for dynamic simulation
WO2011154308A1 (en) 2010-06-08 2011-12-15 Proyecto De Biomedicina Cima, S.L. New compositions and cell therapy methods for the treatment of cirrhosis
JP6272781B2 (ja) 2012-01-06 2018-01-31 エンボライン， インコーポレイテッド 統合された塞栓保護デバイス
RS60026B1 (sr) 2013-02-18 2020-04-30 Vegenics Pty Ltd Molekuli koji vezuju ligande i njihove upotrebe
US11578110B2 (en) 2015-08-25 2023-02-14 Histide Ag Compounds for inducing tissue formation and uses thereof
EP4541810A3 (en) * 2015-08-25 2026-03-18 Histide AG Compounds for inducing tissue regeneration and uses thereof
US10617509B2 (en) 2015-12-29 2020-04-14 Emboline, Inc. Multi-access intraprocedural embolic protection device
JP7557475B2 (ja) 2019-02-13 2024-09-27 エンボライン， インコーポレイテッド 統合された塞栓保護デバイスを伴うカテーテル

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK135983D0 (da) 1983-03-25 1983-03-25 Novo Industri As Maltogen amylaseenzymprodukt og fremgangsmade til dets fremstilling og anvendelse
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5968778A (en) * 1989-01-12 1999-10-19 Jurgen Hoppe PDGF-AB, preparation process and pharmaceuticals containing them
US5194596A (en) * 1989-07-27 1993-03-16 California Biotechnology Inc. Production of vascular endothelial cell growth factor
JP3024311B2 (ja) 1991-10-03 2000-03-21 味の素株式会社 Ｉｌ−２受容体重鎖に結合するポリペプチド
JPH05271294A (ja) 1992-01-24 1993-10-19 Japan Found Cancer Res ヒトプロヒビチンおよびそれをコードするｄｎａ
US5599559A (en) 1992-07-27 1997-02-04 Pfizer Inc. Calcium channel blocking polypeptide from agelenopsis aperta and therapeutic methods employing it
EP0751992B1 (en) * 1994-03-08 2005-11-09 Human Genome Sciences, Inc. Vascular endothelial growth factor 2
US5814464A (en) 1994-10-07 1998-09-29 Regeneron Pharma Nucleic acids encoding TIE-2 ligand-2
US6221839B1 (en) * 1994-11-14 2001-04-24 Helsinki University Licensing Ltd. Oy FIt4 ligand and methods of use
US6645933B1 (en) 1995-08-01 2003-11-11 Helsinki University Licensing Ltd. Oy Receptor ligand VEGF-C
JPH08185216A (ja) 1994-12-28 1996-07-16 Meidensha Corp 工具姿勢パラメータ設定方法及びロボット制御装置
US5928939A (en) 1995-03-01 1999-07-27 Ludwig Institute For Cancer Research Vascular endothelial growth factor-b and dna coding therefor
EP0815221B1 (en) 1995-03-02 2003-10-22 AMRAD Operations Pty.,Ltd. A novel growth factor and a genetic sequence encoding same
WO1996039421A1 (en) 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Human vascular endothelial growth factor 3
DE69638142D1 (de) 1995-09-29 2010-04-15 Univ Siena Regulierte Gene und ihre Verwendungen
WO1998002543A1 (fr) 1996-07-15 1998-01-22 Chugai Research Institute For Molecular Medicine, Inc. Nouveaux facteurs analogues au vegf
EP1283268A3 (en) * 1996-08-23 2004-01-02 Ludwig Institute For Cancer Research Recombinant vascular endothelial cell growth factor D (VEGF-D)
AU5439998A (en) 1996-12-06 1998-06-29 Zymogenetics Inc. Vascular endothelial growth factor
CN1248286A (zh) 1997-02-18 2000-03-22 路德维格癌症研究所 含有重组血管内皮生长因子b(vegf－b)dna的转基因动物及其用途
WO2000037025A2 (en) * 1998-12-21 2000-06-29 Ludwig Institute For Cancer Research Antibodies to truncated vegf-d and uses thereof
WO2001012669A1 (en) 1999-08-16 2001-02-22 Universita' Degli Studi Di Siena Vegf-d and angiogenic use thereof
NZ587143A (en) 2008-02-12 2011-07-29 Dow Agrosciences Llc Pesticidal compositions

Also Published As

Publication number Publication date
CA2230957A1 (en) 1997-04-10
ES2341864T3 (es) 2010-06-29
WO1997012972A2 (en) 1997-04-10
ATE290077T1 (de) 2005-03-15
EP0853668B2 (en) 2013-03-06
EP0853668B1 (en) 2005-03-02
WO1997012972A3 (en) 1997-06-12
ES2239338T5 (es) 2013-05-31
NO981353L (no) 1998-03-25
ES2239338T3 (es) 2005-09-16
EP1553182A3 (en) 2008-03-05
US20020123481A1 (en) 2002-09-05
DE69634412T2 (de) 2005-12-15
JP2001501442A (ja) 2001-02-06
NO981353D0 (no) 1998-03-25
DE69638142D1 (de) 2010-04-15
IL123649A0 (en) 1998-10-30
EP0853668A2 (en) 1998-07-22
EP1553182B1 (en) 2010-03-03
DE69634412D1 (de) 2005-04-07
EP1553182A2 (en) 2005-07-13
DE69634412T3 (de) 2013-07-04
US8383788B2 (en) 2013-02-26
ATE459715T1 (de) 2010-03-15
AU7142996A (en) 1997-04-28

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