DE69634412D1 - Regulierte gene und ihre verwendungen - Google Patents

Regulierte gene und ihre verwendungen

Info

Publication number
DE69634412D1
DE69634412D1 DE69634412T DE69634412T DE69634412D1 DE 69634412 D1 DE69634412 D1 DE 69634412D1 DE 69634412 T DE69634412 T DE 69634412T DE 69634412 T DE69634412 T DE 69634412T DE 69634412 D1 DE69634412 D1 DE 69634412D1
Authority
DE
Germany
Prior art keywords
regulated genes
protein
therapy
mitogenic activity
purposes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69634412T
Other languages
English (en)
Other versions
DE69634412T2 (de
DE69634412T3 (de
Inventor
Salvatore Oliviero
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UNI DEGLI STUDI DI SIENA SIENA
Universita degli Studi di Siena
Original Assignee
UNI DEGLI STUDI DI SIENA SIENA
Universita degli Studi di Siena
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26307843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69634412(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9519928.7A external-priority patent/GB9519928D0/en
Priority claimed from GBGB9612368.2A external-priority patent/GB9612368D0/en
Application filed by UNI DEGLI STUDI DI SIENA SIENA, Universita degli Studi di Siena filed Critical UNI DEGLI STUDI DI SIENA SIENA
Publication of DE69634412D1 publication Critical patent/DE69634412D1/de
Publication of DE69634412T2 publication Critical patent/DE69634412T2/de
Application granted granted Critical
Publication of DE69634412T3 publication Critical patent/DE69634412T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
DE69634412T 1995-09-29 1996-09-30 Regulierte gene und ihre verwendungen Expired - Lifetime DE69634412T3 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB9519928 1995-09-29
GBGB9519928.7A GB9519928D0 (en) 1995-09-29 1995-09-29 Regulated genes and uses thereof
GB9612368 1996-06-13
GBGB9612368.2A GB9612368D0 (en) 1996-06-13 1996-06-13 Regulated genes and uses thereof
EP96932771A EP0853668B2 (de) 1995-09-29 1996-09-30 Regulierte gene und ihre verwendungen
PCT/IB1996/001113 WO1997012972A2 (en) 1995-09-29 1996-09-30 Regulated genes and uses thereof

Publications (3)

Publication Number Publication Date
DE69634412D1 true DE69634412D1 (de) 2005-04-07
DE69634412T2 DE69634412T2 (de) 2005-12-15
DE69634412T3 DE69634412T3 (de) 2013-07-04

Family

ID=26307843

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69638142T Expired - Lifetime DE69638142D1 (de) 1995-09-29 1996-09-30 Regulierte Gene und ihre Verwendungen
DE69634412T Expired - Lifetime DE69634412T3 (de) 1995-09-29 1996-09-30 Regulierte gene und ihre verwendungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69638142T Expired - Lifetime DE69638142D1 (de) 1995-09-29 1996-09-30 Regulierte Gene und ihre Verwendungen

Country Status (11)

Country Link
US (1) US8383788B2 (de)
EP (2) EP1553182B1 (de)
JP (1) JP4086315B2 (de)
AT (2) ATE459715T1 (de)
AU (1) AU7142996A (de)
CA (1) CA2230957A1 (de)
DE (2) DE69638142D1 (de)
ES (2) ES2239338T5 (de)
IL (1) IL123649A0 (de)
NO (1) NO981353L (de)
WO (1) WO1997012972A2 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6824777B1 (en) 1992-10-09 2004-11-30 Licentia Ltd. Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy
US7423125B2 (en) 1995-08-01 2008-09-09 Vegenics Limited Antibodies to VEGF-C
PT848755E (pt) 1995-09-08 2003-12-31 Genentech Inc Proteina relacionada com o vegf
ATE459715T1 (de) 1995-09-29 2010-03-15 Univ Siena Regulierte gene und ihre verwendungen
AU733322B2 (en) 1996-07-15 2001-05-10 Chugai Seiyaku Kabushiki Kaisha Novel VEGF-like factor
DK2107109T3 (da) * 1996-08-23 2012-09-24 Vegenics Pty Ltd Rekombinant vaskulær endotelcelle-vækstfaktor D (VEGF-D)
WO1998024811A2 (en) * 1996-12-06 1998-06-11 Zymogenetics, Inc. Vascular endothelial growth factor
US7125714B2 (en) 1997-02-05 2006-10-24 Licentia Ltd. Progenitor cell materials and methods
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
CN1345247A (zh) * 1997-12-24 2002-04-17 路德维格癌症研究所 表达血管内皮生长因子d的表达载体和细胞系以及治疗黑素瘤的方法
DE19847422C1 (de) * 1998-10-14 2000-01-13 Forschungszentrum Juelich Gmbh Chinese-Hamster-Ovary-Zellen zur Produktion von Proteinen
CA2354325C (en) 1998-12-07 2011-08-16 Zymogenetics, Inc. Growth factor homolog zvegf3
CA2381985A1 (en) * 1999-08-16 2001-02-22 Universita'degli Studi Di Siena Vegf-d and angiogenic use thereof
ATE377081T1 (de) 2000-02-25 2007-11-15 Ludwig Inst Cancer Res Material und verfahren die hybridvaskularendothelwachstumfaktoren dns und proteine enthalten und screeningverfahren für modulatoren
US7611711B2 (en) 2001-01-17 2009-11-03 Vegenics Limited VEGFR-3 inhibitor materials and methods
CN1494552A (zh) 2001-01-19 2004-05-05 ·��ά��֢�о�Ժ Flt4(VEGFR-3)作为靶用于肿瘤成像和抗肿瘤治疗
JP2005500045A (ja) * 2001-07-12 2005-01-06 ルードビッヒ、インスティテュート、フォー、キャンサー、リサーチ リンパ管内皮細胞材料および方法
US20040214766A1 (en) * 2001-10-01 2004-10-28 Kari Alitalo VEGF-C or VEGF-D materials and methods for treatment of neuropathologies
US20030113324A1 (en) * 2001-10-01 2003-06-19 Kari Alitalo Neuropilin/VEGF-C/VEGFR-3 materials and methods
WO2004070018A2 (en) * 2003-02-04 2004-08-19 Ludwig Institute For Cancer Research Vegf-b and pdgf modulation of stem cells
WO2005016963A2 (en) * 2003-06-12 2005-02-24 Ludwig Institute For Cancer Research Heparin binding veger-3 ligands
US20050043235A1 (en) * 2003-06-12 2005-02-24 Kari Alitalo Use of VEGF-C or VEGF-D in reconstructive surgery
US20060024302A1 (en) 2004-03-05 2006-02-02 Ludwig Institute For Cancer Research Chimeric anti-VEGF-D antibodies and humanized anti-VEGF-D antibodies and methods of using same
ITRM20050367A1 (it) * 2005-07-08 2007-01-09 Univ Siena Uso del vegf-d o di suoi frammenti funzionalmente attivi per la ricostruzione o per la riparazione ossea.
AU2006279462A1 (en) 2005-08-15 2007-02-22 Vegenics Limited Modified VEGF and PDGF with improved angiogenic properties
US9073997B2 (en) * 2007-02-02 2015-07-07 Vegenics Pty Limited Growth factor antagonists for organ transplant alloimmunity and arteriosclerosis
US8571840B2 (en) * 2007-03-28 2013-10-29 Autodesk, Inc. Constraint reduction for dynamic simulation
WO2011154308A1 (en) 2010-06-08 2011-12-15 Proyecto De Biomedicina Cima, S.L. New compositions and cell therapy methods for the treatment of cirrhosis
WO2014124487A1 (en) 2013-02-18 2014-08-21 Vegenics Pty Limited Ligand binding molecules and uses thereof
CA2995310A1 (en) 2015-08-25 2017-03-02 Histide Ag Compounds for inducing tissue formation and uses thereof
US20190016770A1 (en) * 2015-08-25 2019-01-17 Histide Ag Compounds for inducing tissue formation and uses thereof
JP2022520573A (ja) 2019-02-13 2022-03-31 エンボライン， インコーポレイテッド 統合された塞栓保護デバイスを伴うカテーテル

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK135983D0 (da) 1983-03-25 1983-03-25 Novo Industri As Maltogen amylaseenzymprodukt og fremgangsmade til dets fremstilling og anvendelse
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5968778A (en) * 1989-01-12 1999-10-19 Jurgen Hoppe PDGF-AB, preparation process and pharmaceuticals containing them
US5194596A (en) * 1989-07-27 1993-03-16 California Biotechnology Inc. Production of vascular endothelial cell growth factor
JP3024311B2 (ja) 1991-10-03 2000-03-21 味の素株式会社 Ｉｌ−２受容体重鎖に結合するポリペプチド
JPH05271294A (ja) 1992-01-24 1993-10-19 Japan Found Cancer Res ヒトプロヒビチンおよびそれをコードするｄｎａ
NZ253611A (en) 1992-07-27 1996-09-25 Pfizer Polypeptide found in the venom of the agelenopsis spider and its use as a calcium channel blocker
DE69434538T2 (de) 1994-03-08 2006-08-10 Human Genome Sciences, Inc. Vaskulärer endothelialer Wachstumsfaktor 2
US5814464A (en) 1994-10-07 1998-09-29 Regeneron Pharma Nucleic acids encoding TIE-2 ligand-2
US6645933B1 (en) 1995-08-01 2003-11-11 Helsinki University Licensing Ltd. Oy Receptor ligand VEGF-C
US6221839B1 (en) * 1994-11-14 2001-04-24 Helsinki University Licensing Ltd. Oy FIt4 ligand and methods of use
JPH08185216A (ja) 1994-12-28 1996-07-16 Meidensha Corp 工具姿勢パラメータ設定方法及びロボット制御装置
US5928939A (en) 1995-03-01 1999-07-27 Ludwig Institute For Cancer Research Vascular endothelial growth factor-b and dna coding therefor
NZ301611A (en) 1995-03-02 2000-02-28 Amrad Operations Pty Ltd a peptide having vascular endothelial growth factor like properties, nucleic acid molecule encoding it and its use
WO1996039421A1 (en) 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Human vascular endothelial growth factor 3
ATE459715T1 (de) 1995-09-29 2010-03-15 Univ Siena Regulierte gene und ihre verwendungen
AU733322B2 (en) 1996-07-15 2001-05-10 Chugai Seiyaku Kabushiki Kaisha Novel VEGF-like factor
DK2107109T3 (da) 1996-08-23 2012-09-24 Vegenics Pty Ltd Rekombinant vaskulær endotelcelle-vækstfaktor D (VEGF-D)
WO1998024811A2 (en) 1996-12-06 1998-06-11 Zymogenetics, Inc. Vascular endothelial growth factor
CA2279573A1 (en) 1997-02-18 1998-08-20 Gabriel Von Euler Transgenic animal with recombinant vascular endothelial growth factor b (vegf-b) dna and uses thereof
ES2259247T3 (es) * 1998-12-21 2006-09-16 Ludwig Institute For Cancer Research Anticuerpos frente a vegf-d truncado y sus usos.
CA2381985A1 (en) 1999-08-16 2001-02-22 Universita'degli Studi Di Siena Vegf-d and angiogenic use thereof
PL2247603T3 (pl) 2008-02-12 2017-04-28 Dow Agrosciences Llc Kompozycje szkodnikobójcze

Also Published As

Publication number Publication date
NO981353D0 (no) 1998-03-25
ES2239338T5 (es) 2013-05-31
JP4086315B2 (ja) 2008-05-14
ATE459715T1 (de) 2010-03-15
DE69634412T2 (de) 2005-12-15
EP1553182A2 (de) 2005-07-13
NO981353L (no) 1998-03-25
WO1997012972A2 (en) 1997-04-10
ES2239338T3 (es) 2005-09-16
EP0853668B1 (de) 2005-03-02
EP0853668B2 (de) 2013-03-06
DE69634412T3 (de) 2013-07-04
EP0853668A2 (de) 1998-07-22
DE69638142D1 (de) 2010-04-15
IL123649A0 (en) 1998-10-30
CA2230957A1 (en) 1997-04-10
ES2341864T3 (es) 2010-06-29
US8383788B2 (en) 2013-02-26
WO1997012972A3 (en) 1997-06-12
JP2001501442A (ja) 2001-02-06
ATE290077T1 (de) 2005-03-15
US20020123481A1 (en) 2002-09-05
AU7142996A (en) 1997-04-28
EP1553182B1 (de) 2010-03-03
EP1553182A3 (de) 2008-03-05

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Legal Events

Date Code Title Description
8363 Opposition against the patent