WO2000028027A3 - Corticosteroid synthesis-associated genes - Google Patents

Corticosteroid synthesis-associated genes Download PDF

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Publication number
WO2000028027A3
WO2000028027A3 PCT/US1999/025457 US9925457W WO0028027A3 WO 2000028027 A3 WO2000028027 A3 WO 2000028027A3 US 9925457 W US9925457 W US 9925457W WO 0028027 A3 WO0028027 A3 WO 0028027A3
Authority
WO
WIPO (PCT)
Prior art keywords
associated genes
corticosteroid synthesis
genes
synthesis
provides
Prior art date
Application number
PCT/US1999/025457
Other languages
French (fr)
Other versions
WO2000028027A2 (en
Inventor
Michael G Walker
Wayne Volkmuth
Tod M Klingler
Original Assignee
Incyte Pharma Inc
Michael G Walker
Wayne Volkmuth
Tod M Klingler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Michael G Walker, Wayne Volkmuth, Tod M Klingler filed Critical Incyte Pharma Inc
Priority to CA002349761A priority Critical patent/CA2349761A1/en
Priority to JP2000581194A priority patent/JP2002529086A/en
Priority to AU14578/00A priority patent/AU1457800A/en
Priority to EP99971852A priority patent/EP1124958A2/en
Publication of WO2000028027A2 publication Critical patent/WO2000028027A2/en
Publication of WO2000028027A3 publication Critical patent/WO2000028027A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The invention provides novel corticosteroid synthesis-associated genes and polypeptides encoded by those genes. The invention also provides expression vectors, host cells, antibodies, antisense molecules and ribozymes. The invention also provides methods for diagnosing, treating or preventing diseases associated with the altered expression of corticosteroid synthesis-associated genes.
PCT/US1999/025457 1998-11-06 1999-10-28 Corticosteroid synthesis-associated genes WO2000028027A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002349761A CA2349761A1 (en) 1998-11-06 1999-10-28 Corticosteroid synthesis-associated genes
JP2000581194A JP2002529086A (en) 1998-11-06 1999-10-28 Corticosteroid synthesis related genes
AU14578/00A AU1457800A (en) 1998-11-06 1999-10-28 Corticosteroid synthesis-associated genes
EP99971852A EP1124958A2 (en) 1998-11-06 1999-10-28 Corticosteroid synthesis-associated genes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15526998P 1998-11-06 1998-11-06
US60/155,269 1998-11-06

Publications (2)

Publication Number Publication Date
WO2000028027A2 WO2000028027A2 (en) 2000-05-18
WO2000028027A3 true WO2000028027A3 (en) 2000-11-30

Family

ID=22554737

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/025457 WO2000028027A2 (en) 1998-11-06 1999-10-28 Corticosteroid synthesis-associated genes

Country Status (5)

Country Link
EP (1) EP1124958A2 (en)
JP (1) JP2002529086A (en)
AU (1) AU1457800A (en)
CA (1) CA2349761A1 (en)
WO (1) WO2000028027A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1368472A2 (en) * 2001-02-09 2003-12-10 Incyte Genomics, Inc. Molecules for disease detection and treatment

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994029434A1 (en) * 1993-06-09 1994-12-22 The Regents Of The University Of California Cholesterol disposal fusion enzymes
WO1998039446A2 (en) * 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 70 human secreted proteins

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994029434A1 (en) * 1993-06-09 1994-12-22 The Regents Of The University Of California Cholesterol disposal fusion enzymes
WO1998039446A2 (en) * 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 70 human secreted proteins

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL EBI, Hinxton, UK; 14 December 1996 (1996-12-14), HILLIER, L. ET AL.: "The WashU-Merck EST Project", XP002137348 *
DATABASE EMBL EBI, Hinxton, UK; 18 August 1998 (1998-08-18), NCI-CGAP, XP002137347 *

Also Published As

Publication number Publication date
AU1457800A (en) 2000-05-29
CA2349761A1 (en) 2000-05-18
JP2002529086A (en) 2002-09-10
EP1124958A2 (en) 2001-08-22
WO2000028027A2 (en) 2000-05-18

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