JP4014764B2 - Hair restorer - Google Patents

Description

【００１０】
その結果を表２に示す。
No. １＝製造例１で作成した凍結乾燥品を１％含むエタノール：プロピレングリコール：水の４：４：２の溶液
No. ２＝実施例１
No. ３＝Ａ社育毛剤
No. ４＝Ｂ社育毛剤
No. ５＝エタノール：プロピレングリコール：水の４：４：２の溶媒
【００１１】

【００１２】
（試験法２）頭髪の薄い男性２０名を対象に３か月間実施例１を朝夕２回使用してもらった。その結果を表３に示す。

となった。
【００１３】
【発明の効果】
海ぶどうの溶剤抽出物或いはこれを含む化粧料を皮膚に塗布することにより、マウス試験、人間の官能検査の何れによっても顕著な育毛効果があることが判明した。海ぶどうの抽出物は、食用として利用され、安全性については実証されており、又入手も容易である。育毛料として効果も優れ、安心して使用できる。[0001]
[Industrial application fields]
The present invention relates to a hair restorer containing an extract of sea grapes.
[0002]
[Prior art]
There are many patents and raw materials for hair restorers, but generally speaking, when natural products are raw materials, the effect is weak, and synthetic products may have side effects. The sea grapes are called the scientific name Caulerpa lentillifera J.Agardoh. It is a tropical seaweed of the family Iwataceae, consisting of leaves with many 2mm grains and stems and roots for fixing to the seabed.
[0003]
[Problems to be solved by the invention]
An object of the present invention is to find a substance having a hair-growth action from an extract of seaweed that has been demonstrated to be safe for food and the like.
[0004]
[Means for Solving the Problems]
The inventors of the present invention have tested many plants and seaweeds that have been used for other purposes such as edible foods, have demonstrated safety and are easily available, and as a result, sea grapes are very effective as hair restorers. And the present invention has been reached. Sea grapes are already on the market as food and are easy to obtain.
[0005]
That is, the present invention is a hair restorer containing a solvent extract of sea grapes. For sea grapes, in order to increase the extraction effect, it is effective to use dry sea grapes and extract with an organic solvent or water. As an organic solvent to be used, extraction is performed using a solvent such as ethanol, methanol, 1.3 butylene glycol, glycerin, propylene glycol, etc., but generally extraction with a mixture of ethanol and water is performed after extraction. Solvent removal is not necessary and is considered as the easiest method. In the case of this ethanol extract or other solvent, the solvent is removed to obtain a dry product (although the ethanol extract or ethanol may be removed as a matter of course), and other cosmetic raw materials are blended into a formulation. The blending amount of the extract varies depending on conditions such as the form of use and purpose, and the coexistence of other hair-growth raw materials, but is 0.0001 to 15% by weight, preferably 0.0005 to 5% by weight in terms of dry matter.
[0006]
【Example】
The present invention will be described more specifically with reference to the following examples. However, the present invention is not limited to the examples.
[0007]
(Production Example 1) 100 g of sea grapes (dried product) was immersed in 1000 ml of 50% ethanol aqueous solution and left for 10 days with occasional stirring. This was filtered, concentrated under reduced pressure, and lyophilized.
[0008]
(Example 1) Hair growth lotion A Vitamin E 0.5
Polyoxyethylene hydrogenated castor oil (60 EO) 1.0
Polyoxyethylene sorbitan monostearate (20E.O.) 2.5
Fragrance 0.1
B
1,3 Butylene glycol 5.0
Ethanol 60.0
Production Example 1 Extract 1.0
Purified water 29.9
The production method A is weighed and dissolved by heating while stirring. The remaining raw material of B is weighed and added to A while stirring.
[0009]
(Test method 1)
Animal experiments = C3H mice, males, 7-week old mice were preliminarily raised for 1 week and then subjected to experiments.
Breeding conditions = Feed is MF (manufactured by Oriental Yeast Co., Ltd.) and drinking water is tap water.
Test method: The left and right skins of the back of the mice were shaved with an electric clipper, then depilated with a hair removal cream, and the site was thoroughly washed with warm water and then wiped. Thereafter, a sample was applied to one side, and the other was applied with a 0.2 ml syringe without application or with a formulation excluding the evaluation substance. Application was continued twice a day (morning and evening) from the next day after hair removal.
Judgment = Visual determination of the coated part and the control part was carried out according to the criteria shown in Table 1 at appropriate intervals.

[0010]
The results are shown in Table 2.
No. 1 = A 4: 4: 2 solution of ethanol: propylene glycol: water containing 1% of the lyophilized product prepared in Production Example 1
No. 2 = Example 1
No. 3 = Company A hair restorer
No. 4 = Company B hair restorer
No. 5 = A solvent of ethanol: propylene glycol: water 4: 4: 2

[0012]
(Test Method 2) Example 1 was used twice a day in the morning and evening for 20 men with thin hair. The results are shown in Table 3.

It became.
[0013]
【The invention's effect】
By applying a solvent extract of sea grapes or a cosmetic containing the same to the skin, it has been found that both a mouse test and a human sensory test have a remarkable hair-growth effect. Sea grape extract is used for food, has proven its safety, and is easily available. It is also effective as a hair restorer and can be used with confidence.

Claims (1)

Hair restorer containing sea grape extract