JP3989951B2 - 組み合わせ髄膜炎ワクチン - Google Patents

組み合わせ髄膜炎ワクチン Download PDF

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Publication number
JP3989951B2
JP3989951B2 JP51517596A JP51517596A JP3989951B2 JP 3989951 B2 JP3989951 B2 JP 3989951B2 JP 51517596 A JP51517596 A JP 51517596A JP 51517596 A JP51517596 A JP 51517596A JP 3989951 B2 JP3989951 B2 JP 3989951B2
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Japan
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vaccine
antibody
prp
infants
hib
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JP51517596A
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Japanese (ja)
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JPH10509701A (ja
Inventor
コスタンテ セッカリーニ，
パオロ コスタンティーノ，
サンドロ ダアスセンジ，
フランシスコ ノレッリ，
アルド ギアノッジ，
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カイロン ソチエタ ア レスポンサビリタ リミタータ
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Application filed by カイロン ソチエタ ア レスポンサビリタ リミタータ filed Critical カイロン ソチエタ ア レスポンサビリタ リミタータ
Publication of JPH10509701A publication Critical patent/JPH10509701A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/831—Drug, bio-affecting and body treating compositions involving capsular polysaccharide of bacterium, e.g. polyribosyl ribitol phosphate

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
JP51517596A 1994-11-02 1995-11-02 組み合わせ髄膜炎ワクチン Expired - Fee Related JP3989951B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9422096.9 1994-11-02
GB9422096A GB9422096D0 (en) 1994-11-02 1994-11-02 Combined meningitis vaccine
PCT/IB1995/001006 WO1996014086A1 (en) 1994-11-02 1995-11-02 Combined meningitis vaccine

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007083117A Division JP4871770B2 (ja) 1994-11-02 2007-03-27 組み合わせ髄膜炎ワクチン

Publications (2)

Publication Number Publication Date
JPH10509701A JPH10509701A (ja) 1998-09-22
JP3989951B2 true JP3989951B2 (ja) 2007-10-10

Family

ID=10763774

Family Applications (3)

Application Number Title Priority Date Filing Date
JP51517596A Expired - Fee Related JP3989951B2 (ja) 1994-11-02 1995-11-02 組み合わせ髄膜炎ワクチン
JP2007083117A Expired - Fee Related JP4871770B2 (ja) 1994-11-02 2007-03-27 組み合わせ髄膜炎ワクチン
JP2010236921A Withdrawn JP2011016850A (ja) 1994-11-02 2010-10-21 組み合わせ髄膜炎ワクチン

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2007083117A Expired - Fee Related JP4871770B2 (ja) 1994-11-02 2007-03-27 組み合わせ髄膜炎ワクチン
JP2010236921A Withdrawn JP2011016850A (ja) 1994-11-02 2010-10-21 組み合わせ髄膜炎ワクチン

Country Status (12)

Country Link
US (1) US6251401B1 (enExample)
EP (3) EP2204185A1 (enExample)
JP (3) JP3989951B2 (enExample)
AT (1) ATE246936T1 (enExample)
CA (2) CA2689871A1 (enExample)
CY (1) CY2423B1 (enExample)
DE (1) DE69531501T3 (enExample)
DK (1) DK0789587T4 (enExample)
ES (1) ES2204967T5 (enExample)
GB (1) GB9422096D0 (enExample)
PT (1) PT789587E (enExample)
WO (1) WO1996014086A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007169302A (ja) * 1994-11-02 2007-07-05 Chiron Srl 組み合わせ髄膜炎ワクチン

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69708318T3 (de) 1996-08-27 2006-11-16 Novartis Vaccines and Diagnostics, Inc., Emeryville Neisseria meningitidis serogruppe b glykokonjugate und verfahren zu deren verwendung
US6048527A (en) * 1996-08-27 2000-04-11 Chiron Corporation Antibodies that define unique Meningococcal B epitopes and vaccine compositions
AU750702B2 (en) * 1997-05-01 2002-07-25 Chiron Corporation Use of virus-like particles as adjuvants
US20040087020A1 (en) 1997-05-28 2004-05-06 Chiron S.P.A. Culture medium with yeast or soy bean extract as amino acid source and no protein complexes of animal origin
PT1849860E (pt) * 1997-05-28 2011-02-23 Novartis Vaccines & Diagnostic Processo de preparação de um factor imunogénico de corynebacterium diphtheriae utilizando um meio de cultura com extracto de levedura como fonte de aminoácidos e sem complexos proteicos de origem animal
US20070259007A1 (en) * 1999-10-19 2007-11-08 Kruzel Marian L Lactoferrin: an adjuvant for vaccines
EP2292263A3 (en) * 1999-12-02 2011-07-27 Novartis Vaccines and Diagnostics, Inc. Compositions and methods for stabilizing biological molecules upon lyophilization
EP1946769B1 (en) * 2000-06-29 2012-05-30 SmithKline Beecham Biologicals S.A. Multivalent vaccine composition with reduced dose of Haemophilus influenzae type B
GB0108364D0 (en) * 2001-04-03 2001-05-23 Glaxosmithkline Biolog Sa Vaccine composition
JP2004529643A (ja) 2001-04-17 2004-09-30 カイロン コーポレイション 機能活性抗体を誘発する髄膜炎菌性ｂエピトープの分子模倣物
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
AR045702A1 (es) 2001-10-03 2005-11-09 Chiron Corp Composiciones de adyuvantes.
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
GB0302218D0 (en) * 2003-01-30 2003-03-05 Chiron Sri Vaccine formulation & Mucosal delivery
DE60328481D1 (de) * 2002-05-14 2009-09-03 Novartis Vaccines & Diagnostic Schleimhautapplizierter impfstoff, der das adjuvanz chitosan und menigokokkenantigene enthält
US20030124139A1 (en) * 2002-11-20 2003-07-03 Irina Esikova Compositions and methods for stabilizing biological molecules upon lyophilization
DK1587537T3 (da) 2003-01-30 2012-07-16 Novartis Ag Injicerbare vacciner mod multiple meningococ-serogrupper
US7731967B2 (en) 2003-04-30 2010-06-08 Novartis Vaccines And Diagnostics, Inc. Compositions for inducing immune responses
ES2397923T3 (es) 2003-10-02 2013-03-12 Novartis Ag Vacunas líquidas para múltiples serogrupos meningocócicos
GB0500787D0 (en) * 2005-01-14 2005-02-23 Chiron Srl Integration of meningococcal conjugate vaccination
HUE045482T2 (hu) 2005-06-27 2019-12-30 Glaxosmithkline Biologicals Sa Immunogén készítmény
AR064642A1 (es) 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
IN2009KN04098A (enExample) * 2007-06-04 2015-08-28 Novartis Ag
HRP20120433T1 (en) * 2007-10-19 2012-07-31 Novartis@Ag Meningococcal vaccine formulations
AU2008335457B2 (en) 2007-12-07 2015-04-16 Glaxosmithkline Biologicals S.A. Compositions for inducing immune responses
CA2808975C (en) 2010-08-23 2018-10-30 Wyeth Llc Stable formulations of neisseria meningitidis rlp2086 antigens
KR101584871B1 (ko) 2010-09-10 2016-01-22 와이어쓰 엘엘씨 네이세리아 메닝기티디스 orf2086 항원의 비-지질화된 변이체
CA2865745C (en) 2012-03-09 2018-01-09 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
CA2903716C (en) 2013-03-08 2019-04-09 Pfizer Inc. Immunogenic fusion polypeptides
RU2662968C2 (ru) 2013-09-08 2018-07-31 Пфайзер Инк. Иммуногенная композиция против neisseria meningitidis (варианты)
KR20190049940A (ko) 2015-02-19 2019-05-09 화이자 인코포레이티드 나이세리아 메닌지티디스 조성물 및 그의 방법
SG11201906519RA (en) 2017-01-31 2019-08-27 Pfizer Neisseria meningitidis compositions and methods thereof
CA3155669A1 (en) 2019-09-27 2021-04-01 Pfizer Inc. Neisseria meningitidis compositions and methods thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4902506A (en) * 1983-07-05 1990-02-20 The University Of Rochester Immunogenic conjugates
US4451446A (en) * 1982-03-04 1984-05-29 Smithkline-Rit Process for the preparation of polysaccharide-protein complexes from bacterial capsules, obtained products and immunogenic compositions containing them
US4619828A (en) * 1982-07-06 1986-10-28 Connaught Laboratories, Inc. Polysaccharide exotoxoid conjugate vaccines
US4459286A (en) * 1983-01-31 1984-07-10 Merck & Co., Inc. Coupled H. influenzae type B vaccine
IT1187753B (it) * 1985-07-05 1987-12-23 Sclavo Spa Coniugati glicoproteici ad attivita' immunogenica trivalente
US5371197A (en) * 1991-09-24 1994-12-06 Merck & Co., Inc. Protein-dimeric polysaccharide conjugate vaccine
GB9202219D0 (en) * 1992-02-03 1992-03-18 Connaught Lab A synthetic heamophilus influenzae conjugate vaccine
IT1262896B (it) * 1992-03-06 1996-07-22 Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini.
GB9422096D0 (en) * 1994-11-02 1994-12-21 Biocine Spa Combined meningitis vaccine
US5628496A (en) 1995-06-07 1997-05-13 Avm, Inc. Pneumatic spring
US6048527A (en) * 1996-08-27 2000-04-11 Chiron Corporation Antibodies that define unique Meningococcal B epitopes and vaccine compositions

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007169302A (ja) * 1994-11-02 2007-07-05 Chiron Srl 組み合わせ髄膜炎ワクチン
JP2011016850A (ja) * 1994-11-02 2011-01-27 Chiron Srl 組み合わせ髄膜炎ワクチン

Also Published As

Publication number Publication date
JP2007169302A (ja) 2007-07-05
EP1312377A3 (en) 2004-02-04
ES2204967T5 (es) 2008-07-01
ES2204967T3 (es) 2004-05-01
DK0789587T4 (da) 2008-08-04
EP0789587B1 (en) 2003-08-13
CA2204277C (en) 2010-02-02
CY2423B1 (en) 2004-11-12
CA2689871A1 (en) 1996-05-17
WO1996014086A1 (en) 1996-05-17
DK0789587T3 (da) 2003-12-01
EP1312377A2 (en) 2003-05-21
PT789587E (pt) 2003-12-31
JPH10509701A (ja) 1998-09-22
EP0789587B2 (en) 2008-04-02
CA2204277A1 (en) 1996-05-17
EP2204185A8 (en) 2010-10-27
JP4871770B2 (ja) 2012-02-08
DE69531501T3 (de) 2008-11-13
DE69531501D1 (de) 2003-09-18
US6251401B1 (en) 2001-06-26
JP2011016850A (ja) 2011-01-27
EP0789587A1 (en) 1997-08-20
GB9422096D0 (en) 1994-12-21
DE69531501T2 (de) 2004-06-24
ATE246936T1 (de) 2003-08-15
EP2204185A1 (en) 2010-07-07

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