JP3989951B2 - 組み合わせ髄膜炎ワクチン - Google Patents

組み合わせ髄膜炎ワクチン Download PDF

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Publication number
JP3989951B2
JP3989951B2 JP51517596A JP51517596A JP3989951B2 JP 3989951 B2 JP3989951 B2 JP 3989951B2 JP 51517596 A JP51517596 A JP 51517596A JP 51517596 A JP51517596 A JP 51517596A JP 3989951 B2 JP3989951 B2 JP 3989951B2
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Japan
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vaccine
antibody
prp
infants
hib
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JP51517596A
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English (en)
Japanese (ja)
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JPH10509701A (ja
Inventor
コスタンテ セッカリーニ，
パオロ コスタンティーノ，
サンドロ ダアスセンジ，
フランシスコ ノレッリ，
アルド ギアノッジ，
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カイロン ソチエタ ア レスポンサビリタ リミタータ
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Application filed by カイロン ソチエタ ア レスポンサビリタ リミタータ filed Critical カイロン ソチエタ ア レスポンサビリタ リミタータ
Publication of JPH10509701A publication Critical patent/JPH10509701A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/831—Drug, bio-affecting and body treating compositions involving capsular polysaccharide of bacterium, e.g. polyribosyl ribitol phosphate

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
JP51517596A 1994-11-02 1995-11-02 組み合わせ髄膜炎ワクチン Expired - Fee Related JP3989951B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9422096A GB9422096D0 (en) 1994-11-02 1994-11-02 Combined meningitis vaccine
GB9422096.9 1994-11-02
PCT/IB1995/001006 WO1996014086A1 (en) 1994-11-02 1995-11-02 Combined meningitis vaccine

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007083117A Division JP4871770B2 (ja) 1994-11-02 2007-03-27 組み合わせ髄膜炎ワクチン

Publications (2)

Publication Number Publication Date
JPH10509701A JPH10509701A (ja) 1998-09-22
JP3989951B2 true JP3989951B2 (ja) 2007-10-10

Family

ID=10763774

Family Applications (3)

Application Number Title Priority Date Filing Date
JP51517596A Expired - Fee Related JP3989951B2 (ja) 1994-11-02 1995-11-02 組み合わせ髄膜炎ワクチン
JP2007083117A Expired - Fee Related JP4871770B2 (ja) 1994-11-02 2007-03-27 組み合わせ髄膜炎ワクチン
JP2010236921A Withdrawn JP2011016850A (ja) 1994-11-02 2010-10-21 組み合わせ髄膜炎ワクチン

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2007083117A Expired - Fee Related JP4871770B2 (ja) 1994-11-02 2007-03-27 組み合わせ髄膜炎ワクチン
JP2010236921A Withdrawn JP2011016850A (ja) 1994-11-02 2010-10-21 組み合わせ髄膜炎ワクチン

Country Status (12)

Country Link
US (1) US6251401B1 (enExample)
EP (3) EP1312377A3 (enExample)
JP (3) JP3989951B2 (enExample)
AT (1) ATE246936T1 (enExample)
CA (2) CA2689871A1 (enExample)
CY (1) CY2423B1 (enExample)
DE (1) DE69531501T3 (enExample)
DK (1) DK0789587T4 (enExample)
ES (1) ES2204967T5 (enExample)
GB (1) GB9422096D0 (enExample)
PT (1) PT789587E (enExample)
WO (1) WO1996014086A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007169302A (ja) * 1994-11-02 2007-07-05 Chiron Srl 組み合わせ髄膜炎ワクチン

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048527A (en) * 1996-08-27 2000-04-11 Chiron Corporation Antibodies that define unique Meningococcal B epitopes and vaccine compositions
PT939647E (pt) 1996-08-27 2002-04-29 Chiron Corp Glicpconjugados do serogrupo b de neisseria meningitidis e metodos de utilizacao dos mesmos
WO1998050071A1 (en) * 1997-05-01 1998-11-12 Chiron Corporation Use of virus-like particles as adjuvants
EP1849860B1 (en) * 1997-05-28 2010-11-17 Novartis Vaccines and Diagnostics S.r.l. Process for preparing an immunogenic factor of Corynebacterium diphtheriae using a culture medium with yeast extract as aminoacid source and no protein complexes of animal origin
US20040087020A1 (en) 1997-05-28 2004-05-06 Chiron S.P.A. Culture medium with yeast or soy bean extract as amino acid source and no protein complexes of animal origin
US20070259007A1 (en) * 1999-10-19 2007-11-08 Kruzel Marian L Lactoferrin: an adjuvant for vaccines
DK1233784T3 (da) * 1999-12-02 2008-09-01 Novartis Vaccines & Diagnostic Præparater og fremgangsmåder til stabilisering af biologiske molekyler efter lyofilisering
GB0108364D0 (en) * 2001-04-03 2001-05-23 Glaxosmithkline Biolog Sa Vaccine composition
DK1296715T4 (en) * 2000-06-29 2016-03-07 Smithkline Beecham Biolog Multivalent vaccine composition.
CN1306956C (zh) 2001-04-17 2007-03-28 希龙公司 诱导功能活性抗体的脑膜炎球菌b抗原表位的分子模拟物
GB0115176D0 (en) * 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
AR045702A1 (es) 2001-10-03 2005-11-09 Chiron Corp Composiciones de adyuvantes.
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
GB0302218D0 (en) * 2003-01-30 2003-03-05 Chiron Sri Vaccine formulation & Mucosal delivery
DE60328481D1 (de) * 2002-05-14 2009-09-03 Novartis Vaccines & Diagnostic Schleimhautapplizierter impfstoff, der das adjuvanz chitosan und menigokokkenantigene enthält
US20030124139A1 (en) * 2002-11-20 2003-07-03 Irina Esikova Compositions and methods for stabilizing biological molecules upon lyophilization
ES2461350T3 (es) 2003-01-30 2014-05-19 Novartis Ag Vacunas inyectables contra múltiples serogrupos de meningococos
US7731967B2 (en) 2003-04-30 2010-06-08 Novartis Vaccines And Diagnostics, Inc. Compositions for inducing immune responses
NZ546430A (en) 2003-10-02 2009-04-30 Novartis Vaccines & Diagnostic Liquid vaccines for multiple meningococcal serogroups
GB0500787D0 (en) * 2005-01-14 2005-02-23 Chiron Srl Integration of meningococcal conjugate vaccination
LT2351578T (lt) * 2005-06-27 2017-04-10 Glaxosmithkline Biologicals S.A. Vakcinų gavimo būdas
AR064642A1 (es) 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
JP5637848B2 (ja) * 2007-06-04 2014-12-10 ノバルティス アーゲー 髄膜炎ワクチンの製剤化
BR122016015627A2 (pt) * 2007-10-19 2018-10-30 Novartis Ag kit, composição antigênica liofilizada e método para preparação de uma composição imunogênica
EP2244695A1 (en) 2007-12-07 2010-11-03 Novartis AG Compositions for inducing immune responses
RU2580620C2 (ru) 2010-08-23 2016-04-10 ВАЙЕТ ЭлЭлСи СТАБИЛЬНЫЕ КОМПОЗИЦИИ АНТИГЕНОВ Neisseria meningitidis rLP2086
WO2012032489A1 (en) 2010-09-10 2012-03-15 Wyeth Llc Non-lipidated variants of neisseria meningitidis orf2086 antigens
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
CA2865745C (en) 2012-03-09 2018-01-09 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
US9802987B2 (en) 2013-03-08 2017-10-31 Pfizer Inc. Immunogenic fusion polypeptides
RU2662968C2 (ru) 2013-09-08 2018-07-31 Пфайзер Инк. Иммуногенная композиция против neisseria meningitidis (варианты)
AU2016221318B2 (en) 2015-02-19 2020-06-25 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
US10183070B2 (en) 2017-01-31 2019-01-22 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
EP4034157A1 (en) 2019-09-27 2022-08-03 Pfizer Inc. Neisseria meningitidis compositions and methods thereof

Family Cites Families (11)

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US4902506A (en) * 1983-07-05 1990-02-20 The University Of Rochester Immunogenic conjugates
US4451446A (en) 1982-03-04 1984-05-29 Smithkline-Rit Process for the preparation of polysaccharide-protein complexes from bacterial capsules, obtained products and immunogenic compositions containing them
US4619828A (en) * 1982-07-06 1986-10-28 Connaught Laboratories, Inc. Polysaccharide exotoxoid conjugate vaccines
US4459286A (en) * 1983-01-31 1984-07-10 Merck & Co., Inc. Coupled H. influenzae type B vaccine
IT1187753B (it) * 1985-07-05 1987-12-23 Sclavo Spa Coniugati glicoproteici ad attivita' immunogenica trivalente
US5371197A (en) * 1991-09-24 1994-12-06 Merck & Co., Inc. Protein-dimeric polysaccharide conjugate vaccine
GB9202219D0 (en) * 1992-02-03 1992-03-18 Connaught Lab A synthetic heamophilus influenzae conjugate vaccine
IT1262896B (it) * 1992-03-06 1996-07-22 Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini.
GB9422096D0 (en) * 1994-11-02 1994-12-21 Biocine Spa Combined meningitis vaccine
US5628496A (en) 1995-06-07 1997-05-13 Avm, Inc. Pneumatic spring
US6048527A (en) * 1996-08-27 2000-04-11 Chiron Corporation Antibodies that define unique Meningococcal B epitopes and vaccine compositions

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007169302A (ja) * 1994-11-02 2007-07-05 Chiron Srl 組み合わせ髄膜炎ワクチン
JP2011016850A (ja) * 1994-11-02 2011-01-27 Chiron Srl 組み合わせ髄膜炎ワクチン

Also Published As

Publication number Publication date
DE69531501D1 (de) 2003-09-18
EP0789587A1 (en) 1997-08-20
DK0789587T3 (da) 2003-12-01
EP1312377A3 (en) 2004-02-04
EP0789587B1 (en) 2003-08-13
DE69531501T3 (de) 2008-11-13
CY2423B1 (en) 2004-11-12
CA2689871A1 (en) 1996-05-17
JP2007169302A (ja) 2007-07-05
WO1996014086A1 (en) 1996-05-17
ES2204967T5 (es) 2008-07-01
US6251401B1 (en) 2001-06-26
EP0789587B2 (en) 2008-04-02
CA2204277A1 (en) 1996-05-17
EP2204185A8 (en) 2010-10-27
PT789587E (pt) 2003-12-31
ATE246936T1 (de) 2003-08-15
DE69531501T2 (de) 2004-06-24
CA2204277C (en) 2010-02-02
ES2204967T3 (es) 2004-05-01
JP2011016850A (ja) 2011-01-27
EP2204185A1 (en) 2010-07-07
GB9422096D0 (en) 1994-12-21
DK0789587T4 (da) 2008-08-04
JPH10509701A (ja) 1998-09-22
JP4871770B2 (ja) 2012-02-08
EP1312377A2 (en) 2003-05-21

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