JP3981417B2 - 生物試料液体を微容量に分割するための方法と装置 - Google Patents

生物試料液体を微容量に分割するための方法と装置 Download PDF

Info

Publication number
JP3981417B2
JP3981417B2 JP54272898A JP54272898A JP3981417B2 JP 3981417 B2 JP3981417 B2 JP 3981417B2 JP 54272898 A JP54272898 A JP 54272898A JP 54272898 A JP54272898 A JP 54272898A JP 3981417 B2 JP3981417 B2 JP 3981417B2
Authority
JP
Japan
Prior art keywords
zone
liquid
zones
sample
hydrophilic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP54272898A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001522242A (ja
JP2001522242A5 (enExample
Inventor
ウィリアムズ，マイケル・ジー
ハルバーソン，カート・ジェイ
クレジカレック，ゲイリー・イー
ウェイ，アイ−ピン
バーグ，ジェイムズ・ジー
ウィカート，ピーター・ディ
カルハウン，クライド・ディ
デーブ，マーク・ケイ
キウ，ジュン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Co
Original Assignee
3M Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Co filed Critical 3M Co
Publication of JP2001522242A publication Critical patent/JP2001522242A/ja
Publication of JP2001522242A5 publication Critical patent/JP2001522242A5/ja
Application granted granted Critical
Publication of JP3981417B2 publication Critical patent/JP3981417B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5088—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above confining liquids at a location by surface tension, e.g. virtual wells on plates, wires
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/04—Flat or tray type, drawers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/01—Drops
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP54272898A 1997-04-09 1997-08-08 生物試料液体を微容量に分割するための方法と装置 Expired - Lifetime JP3981417B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83839797A 1997-04-09 1997-04-09
US08/838,397 1997-04-09
PCT/US1997/014134 WO1998045406A1 (en) 1997-04-09 1997-08-08 Method and devices for partitioning biological sample liquids into microvolumes

Publications (3)

Publication Number Publication Date
JP2001522242A JP2001522242A (ja) 2001-11-13
JP2001522242A5 JP2001522242A5 (enExample) 2005-05-12
JP3981417B2 true JP3981417B2 (ja) 2007-09-26

Family

ID=25277013

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54272898A Expired - Lifetime JP3981417B2 (ja) 1997-04-09 1997-08-08 生物試料液体を微容量に分割するための方法と装置

Country Status (8)

Country Link
EP (1) EP0973863B1 (enExample)
JP (1) JP3981417B2 (enExample)
AR (1) AR012351A1 (enExample)
AU (1) AU735311B2 (enExample)
BR (1) BR9714569B1 (enExample)
CA (1) CA2286195C (enExample)
DE (1) DE69733366T2 (enExample)
WO (1) WO1998045406A1 (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391578B2 (en) 1997-04-09 2002-05-21 3M Innovative Properties Company Method and devices for partitioning biological sample liquids into microvolumes
DE19754978C2 (de) * 1997-12-11 2000-07-13 Bruker Daltonik Gmbh Probenträger für die MALDI-Massenspektrometrie nebst Verfahren zur Herstellung der Platten und zum Aufbringen der Proben
EP1714699B1 (en) * 1998-01-12 2010-08-18 Massachusetts Institute of Technology System for analyzing a plurality of samples
US6893877B2 (en) 1998-01-12 2005-05-17 Massachusetts Institute Of Technology Methods for screening substances in a microwell array
US6376619B1 (en) 1998-04-13 2002-04-23 3M Innovative Properties Company High density, miniaturized arrays and methods of manufacturing same
US6174699B1 (en) 1999-03-09 2001-01-16 3M Innovative Properties Company Disc assay device with inoculation pad and methods of use
BR0009164A (pt) 1999-03-19 2001-12-26 Genencor Int Placa de teste de múltiplos furos vazados paraseparação de alto desempenho
DE19926728B4 (de) 1999-06-11 2011-08-18 3M Espe Ag, 82229 Verwendung von Trägermaterialien und diagnostisch nutzbaren Zusatzstoffen in Abbildungsverfahren für intraorale Diagnosezwecke
US6482638B1 (en) 1999-12-09 2002-11-19 3M Innovative Properties Company Heat-relaxable substrates and arrays
DE10005600A1 (de) * 2000-02-09 2001-08-16 Bayer Ag Ultraphobes Flächengebilde mit einer Vielzahl von hydrophilen Bereichen
US20020151040A1 (en) 2000-02-18 2002-10-17 Matthew O' Keefe Apparatus and methods for parallel processing of microvolume liquid reactions
WO2001061054A2 (en) 2000-02-18 2001-08-23 Board Of Trustees Of The Leland Stanford Junior University Apparatus and methods for parallel processing of micro-volume liquid reactions
US6492133B1 (en) * 2000-05-01 2002-12-10 3M Innovative Properties Company Reflective disc assay devices, systems and methods
EP1188481A3 (en) * 2000-09-15 2002-05-15 Agfa-Gevaert A Microtiter plate having wells for combinatorial applications
US6783735B2 (en) * 2000-09-15 2004-08-31 Agfa-Gevaert Web material having wells for combinatorial applications
EP1245278A3 (en) * 2000-09-15 2003-12-10 Agfa-Gevaert A web material having microwells for combinatorial applications
DE10061195B4 (de) * 2000-12-08 2004-12-02 3M Espe Ag Verwendung von Abformmassen zur Herstellung von Behandlungsvorrichtungen
US7115232B2 (en) * 2001-07-13 2006-10-03 Hudson Gordon S Fluorescence validation microplate and method of use
DE10207616A1 (de) * 2002-02-22 2003-09-04 Sunyx Surface Nanotechnologies Ultraphober Probenträger mit funktionalen hydrophilen und/oder oleophilen Bereichen
WO2003071274A1 (de) 2002-02-22 2003-08-28 Sunyx Surface Nanotechnologies Gmbh Verwendung von ultraphoben oberflächen mit einer vielzahl hydrophiler bereiche zur analyse von proben
CA2521999A1 (en) 2002-12-20 2004-09-02 Biotrove, Inc. Assay apparatus and method using microfluidic arrays
DE10321042B4 (de) * 2003-01-17 2006-09-21 Greiner Bio-One Gmbh Biochip-Träger
US9005549B2 (en) 2003-01-17 2015-04-14 Greiner Bio-One Gmbh High throughput polymer-based microarray slide
US8007744B2 (en) 2003-01-17 2011-08-30 Greiner Bio-One Gmbh Sample container for analyses
AU2005222618A1 (en) 2004-03-12 2005-09-29 Biotrove, Inc. Nanoliter array loading
US12070731B2 (en) 2004-08-04 2024-08-27 Life Technologies Corporation Methods and systems for aligning dispensing arrays with microfluidic sample arrays
US20060105453A1 (en) 2004-09-09 2006-05-18 Brenan Colin J Coating process for microfluidic sample arrays
DE102008008256A1 (de) * 2007-10-08 2009-04-09 M2P-Labs Gmbh Mikroreaktor
JP5081854B2 (ja) * 2009-03-05 2012-11-28 三井造船株式会社 細胞分離装置、細胞分離システムおよび細胞分離方法
US20130053281A1 (en) * 2010-02-02 2013-02-28 Arash Zarrine-Afsar Fluid sampling device and method of use thereof
WO2011097677A1 (en) * 2010-02-12 2011-08-18 Monash University Printed multi-zone microzone plates
JP5921437B2 (ja) * 2010-09-14 2016-05-24 Ａｇｃテクノグラス株式会社 培養基材
JP5757515B2 (ja) * 2010-10-15 2015-07-29 学校法人立命館 撥水層を有する液滴保持ツールの製造方法
JP5853475B2 (ja) * 2011-08-04 2016-02-09 ニプロ株式会社 細胞培養シャーレ
JP2013047625A (ja) * 2011-08-29 2013-03-07 Sumitomo Bakelite Co Ltd マルチウェルプレート
DE102011082716A1 (de) * 2011-09-14 2013-03-14 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Indikatorelement mit einer von einer in kontakt zu bringenden substanz abhängigen farbgebung
DE102012112494A1 (de) * 2012-12-18 2014-07-03 Karlsruher Institut für Technologie Verfahren zum Übertragen einer Transferflüssigkeit von einer Vorlagefläche in eine Mehrzahl von diskreten Kompartimenten auf einer Zielfläche und Transferfläche zur Durchführung des Verfahrens
JP6156933B2 (ja) * 2014-01-22 2017-07-05 国立大学法人 筑波大学 細胞培養用デバイス
JP2019531730A (ja) * 2016-09-28 2019-11-07 ジェネラル オートメーション ラボ テクノロジーズ インコーポレイテッド 細菌群の関係決定及び他のハイスループット微生物学適用高分解能システム、キット、装置、並びに方法
CN108660068B (zh) * 2018-02-13 2022-04-05 臻准生物工程(山西)有限公司 生物反应芯片及其制备方法
WO2019236309A1 (en) * 2018-06-04 2019-12-12 Dupont Nutrition Biosciences Aps Method for identifying and enumerating specific bacterial populations in an unenriched liquid sample
CN116323001A (zh) 2020-10-13 2023-06-23 伯乐欧洲有限公司 应用于表征食品品质和改进食品安全性的用于靶检测的系统和方法
KR20240013103A (ko) * 2021-04-16 2024-01-30 플렉시움 인코포레이티드 조합 라이브러리용 분석 디바이스
US20250025137A1 (en) * 2021-07-09 2025-01-23 Porex Corporation Device with discrete hydrophilic porous components and method of making the same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61247965A (ja) * 1985-04-25 1986-11-05 Susumu Kogyo Kk 酵素免疫測定法
DE3631066A1 (de) * 1986-09-12 1988-04-14 Rainer Dylla Objekttraeger fuer nasse oder feuchte biologische praeparate, z. b. blut
JPS6396558A (ja) * 1986-10-13 1988-04-27 Nitto Electric Ind Co Ltd 検査プレ−ト用シ−トおよび検査プレ−ト
DE3732142C2 (de) * 1987-09-24 1995-12-21 Heraeus Instr Gmbh Verfahren zur Herstellung einer mit einer Maske versehenen Glasplatte sowie Stempelkörper zur Durchführung des Verfahrens
US5503803A (en) * 1988-03-28 1996-04-02 Conception Technologies, Inc. Miniaturized biological assembly
US5229163A (en) * 1989-12-21 1993-07-20 Hoffmann-La Roche Inc. Process for preparing a microtiter tray for immunometric determinations
JPH04265860A (ja) * 1991-02-21 1992-09-22 Sekisui Chem Co Ltd 免疫測定検査用凝集判定プレート
AU7374796A (en) * 1995-09-27 1997-04-17 Mercury Diagnostics Inc. Direct reading chemical test strip for aqueous solutions

Also Published As

Publication number Publication date
CA2286195C (en) 2006-02-14
EP0973863B1 (en) 2005-05-25
DE69733366T2 (de) 2006-01-26
BR9714569A (pt) 2000-02-15
AR012351A1 (es) 2000-10-18
BR9714569B1 (pt) 2009-05-05
AU735311B2 (en) 2001-07-05
WO1998045406A1 (en) 1998-10-15
EP0973863A1 (en) 2000-01-26
JP2001522242A (ja) 2001-11-13
DE69733366D1 (de) 2005-06-30
AU3829997A (en) 1998-10-30
CA2286195A1 (en) 1998-10-15

Similar Documents

Publication Publication Date Title
JP3981417B2 (ja) 生物試料液体を微容量に分割するための方法と装置
US6391578B2 (en) Method and devices for partitioning biological sample liquids into microvolumes
US6696286B1 (en) Method and devices for detecting and enumerating microorganisms
AU736154B2 (en) Device and methods for determination of analyte in a solution
JP4217378B2 (ja) 微生物の検知および計数の方法および器具
JP6722657B2 (ja) 試料の分割及び分析のためのデバイス及び方法
JP4488628B2 (ja) 接種パッドの付いたディスクアッセイ装置および使用方法
AU744534B2 (en) Disc assay devices and methods of use
MXPA99009030A (en) Method and devices for partitioning biological sample liquids into microvolumes
MXPA00000953A (en) Method and devices for detecting and enumerating microorganisms
MXPA00006124A (en) Disc assay devices and methods of use

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20040809

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20040809

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20061107

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20061026

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20070207

A72 Notification of change in name of applicant

Free format text: JAPANESE INTERMEDIATE CODE: A721

Effective date: 20070207

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20070326

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070507

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20070626

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20070702

R150 Certificate of patent or registration of utility model

Free format text: JAPANESE INTERMEDIATE CODE: R150

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20100706

Year of fee payment: 3

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20110706

Year of fee payment: 4

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20110706

Year of fee payment: 4

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20120706

Year of fee payment: 5

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20120706

Year of fee payment: 5

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20130706

Year of fee payment: 6

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

EXPY Cancellation because of completion of term